Y-doped TiO2 coating with superior bioactivity and antibacterial property prepared via plasma electrolytic oxidation

To improve the bioactivity and antibacterial properties of implant materials. In this study, the biomedical titanium alloy (Ti-6Al-4V) was covered by yttrium doped titanium dioxide (Y-TiO 2 ) coating via a plasma electrolytic oxidation (PEO) method. By changing the concentration of yttrium acetate in the electrolyte, Y-TiO 2 coating with different mass ratios of yttrium were obtained. The structure morphology and chemical composition of the Y-TiO 2 coating were systematically characterized. The results indicated that the porous and micro-nanostructured Y-TiO 2 coatings were constructed by the pores smaller than 4 μm. Definitely yttrium was not only distributed on the surface but also embedded in the coating. Yttrium mainly existed in form of Y 2 O 3 and Y 3+ state in prepared TiO 2 coating. Element release profiles confirmed that yttrium release slowly from Y-TiO 2 for 32 days. Cell culture tests demonstrated that Y-TiO 2 coating exhibited good biocompatibility on osteoblastic precursor cells and fibroblasts cells with increasing doping concentration of yttrium. Bacteriostasis experiments revealed that Y-TiO 2 coating possess excellent antibacterial property against Staphylococcus aureus ( S. aureus ) and Escherichia coli ( E. coli ). Thus, the prepared Y-TiO 2 coating with outstanding biocompatibility and antibacterial capacity provided a preferred strategy for the repair and reconstruction of bone tissues in dentistry and orthopedics.