已核实 DOI PubMed 相关产品: 0

Engineering a lipase B from Candida antactica with efficient perhydrolysis performance by eliminating its hydrolase activity

Journal 2017 · IF 4.259 · 7(1): 1-5 · 发表于 2017 年 3 月 20 日
作者: Wang Xu-Ping,Zhou Peng-Fei,Li Zhi-Gang,Yang Bo,Hollmann Frank,Wang Yong-Hua
阅读全文 在 PubMed 查看

摘要

A Ser105Ala mutant of the lipase B from Candida antarctica enables ‘perhydrolase-only’ reactions. At the example of the chemoenzymatic Baeyer-Villiger oxidation of cyclohexanone, we demonstrate that with this mutant selective oxidation can be achieved in deep eutectic solvent while essentially eliminating the undesired hydrolysis reaction of the product.