The preparation and characterization of electrospun gelatin nanofibers containing chitosan/eugenol-sulfobutyl-β-cyclodextrin nanoparticles

In this study, a multifunctional food packaging material (G-Eug-NPs-NF) based on gelatin nanofiber membranes (G-NF) containing eugenol nanoparticles (Eug-NPs) were prepared. The Eug-NPs were fabricated through the electrostatic self-assembly by using two ionic polysaccharides chitosan and sulfobutylether-β-cyclodextrin (SCD). Compared with G-NF, the G-Eug-NPs-NF exhibited better antioxidant capacity , which positively correlated with Eug-IC concentration, up to 84.17%. In addition, the latter had a good inhibitory effect on Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) , and was more conducive to inhibit the growth of S. aureus . At the same time, the sustained release experiment showed that the incorporation of Eug-NPs in nanofiber membranes improved the sustained release ability of G-Eug-NPs-NF. G-Eug-NPs-NF exhibits the promising application of Eug in food, medicine and other fields.