Development of a Pt-graphene nanocomposite-based solid-phase extraction coupled with ultra-performance liquid chromatography–tandem mass spectrometry for the determination of carbamate pesticides in fish

Abstract In the present work, a potential solid-phase extraction (SPE) material based on graphene anchored with platinum nanoparticles (Pt-Graphene) was prepared and characterized by scanning electron micrographs and transmission electron micrograph. The carbamates residues in fish were enriched by SPE filled with Pt-Graphene and detected by ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS). The proposed extraction protocol exhibited satisfactory recoveries (76.5–115.6%), low limit of quantitation values in μg kg −1 level, and good precision for the studied ten carbamates. These results demonstrated the feasibility of the proposed protocol. The developed Pt-Graphene nanoparticles showed excellent performance for extracting analytes at trace levels, indicating that it could be used as a potential SPE sorbent in food residue analysis. Graphical abstract