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Highly Efficient Pd-Catalyzed Cyanation of Aryl Chlorides and Arenesulfonates with Potassium Ferrocyanide in Aqueous Media

Journal 2010 · IF 2.021 · 139(1): 56-60 · 发表于 2010 年 6 月 12 日
作者: Zhang Junli,Chen Xiaorong,Hu Tongjie,Zhang Yuan,Xu Kunling,Yu Yanpeng,Huang Jun
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摘要

Abstract A highly improved Pd-catalyzed cyanation of aryl chlorides to corresponding benzonitriles was demonstrated in aqueous media. Moreover, Pd-catalyzed cyanation of aryl tosylates and benzenesulfonates with K 4 [Fe(CN) 6 ] was developed under the similar conditions, which extended application scope of the cyanation. Graphical Abstract