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Synthesis of 4H-cyclopenta[c]furan-5(6H)-one derivatives

Journal 2020 · IF 2.233 · 发表于 2020 年 7 月 25 日
作者: Xianxia Tu,Haiyun Peng,Guisheng Deng
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摘要

In Ph 3 PAuCl/AgOTf/TsOH system, 2-diazo-5-alkynyl-1,7-diketo carbonyl compounds were transformed into diazo furans . Rh 2 (OAc) 4 -mediated conversion of the diazo furan derivatives into 4 H -cyclopenta[ c ]furan-5(6 H )-one derivatives was accomplished via C(sp 2 )−H insertion reaction at 4-position on the furan ring.