Silver Chloride Loaded Hollow Mesoporous Silica Particles and Their Application in the Antibacterial Coatings on Denture Base

Hollow mesoporous silica particles(HMSPs) were prepared by using polystyrene microspheres as a template and loaded with silver chloride(AgCl) to act as antibacterial agents. The HMSPs possess radially oriented pore channels and a high loading amount of AgCl. The AgCl loaded HMSPs were then dispersed in hybrid coatings with different mass ratios to fabricate antibacterial coatings. The antibacterial activities of the coatings were tested against Candida albicans (ATCC 10231) and Streptococcus mutants (ATCC 25175). The resulting antibacterial coatings exhibited high antibacterial activities, high hardness, and acceptable adhesion to the substrate.