Graphene oxide doped poly(hydroxymethylated-3,4-ethylenedioxythiophene): enhanced sensitivity for electrochemical determination of rutin and ascorbic acid

A novel graphene oxide doped poly(hydroxymethylated-3,4-ethylenedioxythiophene) (PEDOT-MeOH/GO) composite film was synthesized and utilized as an efficient electrode material for simultaneous detection of rutin and ascorbic acid (AA). PEDOT-MeOH/GO films were synthesized on glassy carbon electrode (GCE) by a facile one-step electrochemical approach and were characterized by scanning electron microscopy, UV-Vis spectroscopy, FTIR spectra and electrochemical methods. Then the PEDOT-MeOH/GO/GCE was applied successfully in the simultaneous detection of rutin and AA. The results showed that the oxidation peak currents of rutin and AA obtained at the PEDOT-MeOH/GO/GCE were much higher than those at the traditional conducting polymer PEDOT/GO/GCE, PEDOT-MeOH/GCE, PEDOT/GCE and bare GCE. Under optimized conditions, the linear ranges for rutin and AA are 20 nmol/L−10 μmol/L and 8 μmol/L−1 mmol/L, respectively. The detection limit is 6 nmol/L for rutin and 2 μmol/L for AA (S/N = 3), which are lower than those of the reported electrochemical sensors.