Magnetically Modified Porous β-Cyclodextrin Polymers for Dispersive Solid-Phase Extraction High-Performance Liquid Chromatography Analysis of Sudan Dyes

Two types of magnetically modified porous β-cyclodextrin polymers (PCDPs) were successfully synthesized. The first type, named MPCDPs(C), was fabricated by co-precipitating PCDPs with Fe 3 O 4 , resulting in a Brunauer–Emmett–Teller (BET) surface area of 106.68 m 2  g −1 . The second type, named MPCDPs(M), was fabricated by grafting PCDPs onto the surface of magnetic microspheres, resulting in a BET surface area of 34.63 m 2  g −1 . Both MPCDPs were found to enable effective extraction and separation of Sudan dyes from foodstuffs and environmental water. Coupled with high-performance liquid chromatography, the limits of detection for Sudan dyes were in the range of 0.013–0.054 ng mL −1 with MPCDPs(C), and 0.028–0.039 ng mL −1 with MPCDPs(M). Recoveries were between 85.8 and 102.8% for spiked food samples and 88.3 and 103.2% for spiked water samples, suggesting that the developed methods are promising for accurate quantification of Sudan dyes at trace levels in foodstuffs and environmental water.