Construction of a sensitive electrochemical sensor based on hybrid 1 T/2H MoS2 nanoflowers anchoring on rGO nanosheets for the voltammetric determination of acetaminophen

In this work, an ultrasensitive electrochemical sensor towards quantitative detection of acetaminophen (AP) based on hybrid of metallic 1 T and semiconductive 2H phase molybdenum disulfide (1 T/2H MoS 2 ) anchored on rGO sensing platform was constructed. The XRD, FESEM, FETEM and XPS analysis indicates that nanoflowers 1 T/2H MoS 2 with walnut-like fold structure were in-situ loaded onto the surface of rGO nanosheets by the hydrothermal approach. The formation of stabilized 1 T MoS 2 is associated with the influence of GO. The electrochemical tests of CV, EIS and DPV show that the hybrid composite MoS 2 /rGO remarkably promoted the detecting performance owing to the increased conductivity of 1 T MoS 2 that can facilitate charge transfer kinetics, the great active sites on both basal and edge of planes of 1 T/2H MoS 2 and the synergic effect of 1 T/2H MoS 2 and rGO. After the test condition optimization, MoS 2 /rGO/GCE sensor has great electrocatalytic activity towards AP with wide linear range of 0.005–300 μM and low limit of detection of 1.7 nM (S/N = 3). Furthermore, the sensor shows excellent stability, repeatability, reproducibility and anti-interference performance. All results proved that the GO-assisted hydrothermal prepared hybrid 1 T/2H MoS 2 /rGO is promising material for electrochemical analysis.