Diverse reactivity to hypochlorite and copper ions based on a novel Schiff base derived from vitamin B6 cofactor

A new Schiff base receptor (2-amino-3-(((3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)amino)maleonitrile ( GAL )) has been synthesized and such diaminomaleonitrile-based molecular framework is observed to be water soluble . GAL possesses both colorimetric and “off-on” fluorescent response in the presence of ClO − . The response time has been controlled within 6 min. The limit of detection (LOD) has been calculated to be 47.5 nM. The addition of Cu 2+ can only induce clear color evolution from pale to deep yellow (LOD: 0.22 μM) and no fluorescence changes are found. Moreover, its reliability and practicality are verified via the determination of ClO − in spiked samples of tap water and pond water. The exploration of bioactive vitamin B6 cofactor as a sensing platform will open a new way for multiple target recognition in competitive mediums.