High-performance electrochemical glucose sensing enabled by Cu(TCNQ) nanorod array

It is highly attractive to construct stable enzyme-free glucose sensors based on three-dimensional direct electrochemical detection of glucose. In this paper, a copper 7,7,8,8-tetracyanoquinodimethane (Cu(TCNQ)) nanorod array on Cu foam (Cu(TCNQ) NA/CF) is proposed as an efficient catalyst for electrochemical glucose oxidation in alkaline conditions. When Cu(TCNQ) NA/CF was used as the enzyme-free sensory of glucose, the sensor showed a response time within 3 s, a wide linear detection in the range 0.001–10.0 mM, the minimum limit of detection was as low as 10 nM (S/N = 3), and it had a high sensitivity of 26 987 μA mM−1 cm−2. Moreover, this sensor also possesses long-term stability, high selectivity, reproducibility, and actual applications for fresh human serum sample analysis is also successfully accepted.