Synthesis of Diones via Visible Light-Induced Oxidation of α-Hydroxy Ketone Derivatives

Graphical In the presence of CBrCl3 and ruthenium photocatalyst, the corresponding dione was obtained by visible light induced oxidation of α-hydroxyl ketone derivatives with the yield of 49%–95%. It has the advantages of medium to excellent yield, good functional group tolerance, and mild reaction conditions. A visible light-induced oxidation of α-hydroxy ketone derivatives is reported, which is carried out in the presence of CBrCl 3 and ruthenium photocatalyst, and the corresponding diketones are obtained in 49-95% yields. This reaction has the advantages of moderate to excellent yields, good functional group tolerance, and mild reaction condition. The free radical reaction process was confirmed by the addition of radical scavenger 2,2,6,6-tetramethylpiperidi-1-oxy (TEMPO). The fluorescence quenching experiment indicated that CBrCl 3 was participated in the oxidation quenching cycle.