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RNHSO2F as reliable azasulfene precursors for the construction of sulfamates

Journal 2024 · IF 2.2 · 发表于 2024 年 12 月 26 日
作者: Taijie Guo,Wei Wang,Long Xu,Jiajia Dong
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摘要

Here we report the utilization of NH-sulfamoyl fluorides (RNHSO2F) as reliable SuFEx synthons for the construction of various sulfamate esters. By using potassium fluoride as base, we are able to convert RNHSO2F to azasulfene intermediates under mild conditions and guarantee their further efficent ligation with phenols and alcohols.