Facile synthesis of highly ordered mesoporous Fe3O4 with ultrasensitive detection of dopamine

Dopamine (DA) detection is significant for the prevention of unfavorable neuronal illness. However, the detection of DA with low concentration still face tremendous challenges. In this study, highly ordered mesoporous Fe 3 O 4 materials were synthesized as a biosensor by using mesoporous silica KIT-6 with different aging temperature as hard template. The ordered mesoporous Fe 3 O 4 with high surface area modified glassy carbon electrode shows the high sensitivity for detecting DA. Fe 3 O 4 -40 mesoporous material modified electrode has the highest catalytic activity to DA with a sensitivity of 0.053 nA nM −1 and a detection limit of 0.8 nM (S/N = 3). The results indicating that the mesoporous Fe 3 O 4 material modified electrode exhibits high sensitivity to determine DA at low levels, which can be used for DA real-time monitoring in neutral biological media.