A gas chromatographic stationary of homochiral metal-peptide framework material and its applications

Homochiral metal-organic frameworks(HMOFs) have special properties, such as high surface area, fasci-nating structures and excellent chemical and thermal stability and they have broad application prospects. In this work, we reported the use of HMOF Co- L -GG( L -GG, dipeptide H-Gly- L -Glu) as the stationary phase for separating race-mates in gas chromatography. Co- L -GG coated fused silica capillary column(10 m×250 μm i.d.) was prepared via a dynamic coating method. Thirty racemates belonging to different classes of organic compounds were resolved in-cluding halohydrocarbons, ketones, esters, ethers, organic acids, epoxyalkanes, alcohols and sulfoxides. When com-pared with the previously reported chiral MOFs-coated capillary columns, the Co- L -GG coated column exhibited broader chiral resolution ability towards chiral compounds.