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Microwave-assisted Michael addition of 2-amino pyridine to chalcones under catalyst-free conditions

Journal 2014 · IF 1.54 · 41(8): 5809-5819 · 发表于 2014 年 5 月 30 日
作者: Zhao Bing,Jiang Lili,Liu Zhuo,Deng Qigang,Wang Liyan,Song Bo,Gao Yan
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摘要

A microwave-assisted, convenient, efficient, and catalyst-free procedure is described for the synthesis of 1,3-diphenyl-3-(pyridin-2-ylamino)propan-1-one derivatives by Michael addition of 2-aminopyridine to the chalcones. Short reaction times, simple reaction, easy of product isolation, high yields, and clean work-up are the advantages of this method.