Electrochemical and bio-sensing platform based on a novel 3D Cu nano-flowers/layered MoS2 composite

A novel 3D nano-flower-like Cu/multi-layer molybdenum disulfide composite (CuNFs/MoS 2 ) modified glassy carbon electrode (GCE) has been successfully constructed. It was a highly sensitive and selective non-enzymatic hydrogen peroxide (H 2 O 2 ) and glucose biosensor . The morphology of the obtained CuNFs-MoS 2 nano-particles was investigated with the use of a scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD) and energy dispersive X-ray spectroscopy (EDS). The physicochemical properties of the modified electrode were characterized at each of the construction stages with the use of an electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV) techniques. The new sensor combined the advantages of MoS 2 and CuNFs , and exhibited high electro-catalytic activity toward H 2 O 2 and glucose. Quantitative analysis of H 2 O 2 and glucose was carried out with the use of the amperometric i – t method. Linear ranges were obtained between 0.04–1.88   μM and 1.88–35.6   μM for H 2 O 2 and 1–20   μM and 20–70   μM for glucose, and their corresponding limits of detection (LOD) were 0.021   μM and 0.32   μM. This novel sensor was successfully applied for the quantitative analysis of H 2 O 2 in tap water and glucose in human serum samples.