Palladium catalyzed selective amination of B(7)-H for synthesis of o-carborane fused isoquinolinones

A palladium catalyzed intramolecular amination of B(7)-H for synthesis of o -carborane fused isoquinolinones has been developed. Kinds of o -carborane fused isoquinolinones decorated with active groups have been synthesized with good to excellent yields. A plausible mechanism involving palladium catalyzed electrophilic B-H activation/amination was proposed.