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One-Pot Synthesis Bodipy Nano-Precipitations for Prostate Cancer Treatment

Journal 2022 · IF 0.144 · 12(8): 1537-1541 · 发表于 2022 年 8 月 1 日
作者: Wang Jianan,Tian Chao,Cao Zhengguo
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摘要

Here in this study, we proposed a polystyrene maleic anhydride (PSMA) stabilized Bodipy nanoparticles (PB NPs) in a one-pot approach for the photodynamic therapy (PDT) of prostate cancer. The nanoparticle formed by precipitation method was then employed to treat PC-3 cells and PC-3 tumor bearing nude mice model. It was shown that this platform showed promising anticancer performance than free bodipy with reduced side effects.