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A One-pot Green Synthesis of Alkylidenesuccinimides

Journal 2011 · IF 0.773 · 29(9): 1906-1910 · 发表于 2011 年 9 月 28 日
作者: Lin Yan,Wenguo Yang,Lixin Li,Yang Shen,Zhiyong Jiang
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摘要

A mild and facile Wittig reaction between N -substituted maleimides and aldehydes has been developed. Various synthetically valuable alkylidenesuccinimides were obtained from this one-pot reaction in high yields (up to 99%). The product was obtained by simple filtration and no extra purification was necessary. Ethanol, an environment-benign solvent, was found to be a suitable reaction medium.