Palladium catalyzed/counter ion tuned selective methylation of o-carboranes

The palladium catalyzed/counter ion tuned selective methylation of 9-amide- o -carboranes on B(4) and B(12) has been developed, and a series of o -carborane derivatives decorated with various groups have been synthesized with moderate yields. The in situ formed palladium species via counter ion exchange was proposed for the tunable B–H activation.