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Cu-catalyzed decarboxylative iodination of aryl carboxylic acids with NaI: A practical entry to aryl iodides under aerobic conditions

Journal 2018 · IF 2.125 · 59(51): 4458-4461 · 发表于 2018 年 11 月 13 日
作者: Zhengjiang Fu,Yongqing Jiang,Ligao Jiang,Zhaojie Li,Shengmei Guo,Hu Cai
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摘要

A simple and practical Cu-catalyzed decarboxylative iodination has been well established under aerobic condition, which provides a useful method to synthesize aryl iodides in moderate to good yields with the use of (hetero)aryl carboxylic acids and NaI as starting materials. Thiabendazole has been prepared via a three-step procedure to show synthetic practicability of the protocol.