Cycloastragenol Derivatives Improve Tyrosine Metabolism, Regulate TLR4/NF‐κB/TERT Signaling Pathways, and Inhibit MPTP Induced Neuroinflammation and PD Symptoms

Cycloastragenol derivatives regulate the TLR4/NF‐κB/TERT signaling pathway and tyrosine metabolism, breaking the vicious cycle of “inflammation‐aging” and improving symptoms of Parkinson's disease. This study provides direction for the application of natural products in the development of PD drugs.