Selenized Ti3C2 MXene/MOF-Derived Porous Carbon Nanocomposite for the Simultaneous Electrochemical Determination of Acetaminophen and p-Aminophenol

Se@Ti3C2/CNs nanocomposites were successfully prepared through combining Ti3C2 MXene with ZIF-8-derived nitrogen-doped carbon materials (CNs) and employing a selenization strategy. The morphology and structural information of the material were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), energy-dispersive X-ray spectroscopy (EDS) and X-ray photoelectron spectroscopy (XPS). Electrochemical investigation showed that this material exhibited outstanding electrocatalytic performance to acetaminophen (AP) and p-aminophenol (4-AP) and could detect them simultaneously in wider linear ranges of 0.10–400.00 μM and 0.10–330.00 μM respectively with detection limits of 45.7 and 46.0 nM, respectively. Analysis of water samples and artificial urine shows that the sensor based on this material provides satisfactory results for AP and 4-AP with satisfactory selectivity (current change is less than 5% of the initial value) and stability (current retains above 95% of its initial response after 10 days of storage), which offers potential applications in drug analysis and environmental monitoring.