Bionic Cooling Skin for Infected Wound Healing

A bionic cooling skin with a hierarchical Janus nanofiber structure was fabricated by combining solvent welding technology with single-sided visible light-responsive metal–organic frameworks. This unique design simultaneously realized effective passive cooling (~4 °C reduction under sunlight) through high mid-infrared emissivity and on-demand antibacterial activity via photocatalytic reactive oxygen species generation. The bionic skin dressing closely mimics natural skin in mechanical properties and permeability while demonstrating superior healing performance for infected wound, with mechanistic insights supported by comprehensive gene expression analysis.