Integrated adsorption and peroxymonosulfate activation over magnetic Co–Mn Prussian blue analogue-derived catalyst for multiple mycotoxin detoxification

A magnetic CoMn-PBA*-based adsorption–activation system was developed for mycotoxin detoxification. • Synergistic adsorption and PMS activation enabled rapid removal of AFB₁, ZEN, and OTA. • Efficient detoxification was achieved in edible oil and grape juice while maintaining acceptable quality. • The catalyst exhibited good reusability and stable performance during repeated cycles. • Zebrafish assays demonstrated reduced toxicity of degradation products and favorable preliminary biosafety. Aflatoxin B 1 (AFB 1 ), zearalenone (ZEN), and ochratoxin A (OTA) are widespread contaminants in food systems, while existing detoxification approaches often suffer from limited efficiency and poor applicability in complex matrices. Herein, a magnetic cobalt–manganese Prussian blue analogue-derived catalyst was developed by integrating adsorption with peroxymonosulfate (PMS) activation for synergistic detoxification of multiple mycotoxins. The catalyst exhibited rapid adsorption toward AFB₁ with a removal efficiency of up to 98%, while PMS activation generated reactive species, including SO₄•⁻ and •OH, which further promoted the degradation of ZEN and OTA. As a result, efficient removal of all three mycotoxins was achieved within 30   min through the combined adsorption–oxidation process. The catalyst also maintained considerable detoxification performance after four consecutive cycles, indicating acceptable reusability. Importantly, the treated edible oils and grape juice maintained comparable quality parameters to the untreated controls, indicating minimal impact on food quality and the feasibility in complex food matrices. Zebrafish assays further indicated low acute toxicity of the catalyst and treated products under the tested conditions, providing preliminary evidence of biosafety. This study provides a promising integrated adsorption–activation strategy for efficient mycotoxin detoxification in complex food matrices. Download: Download high-res image (332KB) Download: Download full-size image