SEPARATION AND PURIFICATION TECHNOLOGY
·
2019
·
IF 5.107
Yi Zhao,Han Wang
Three kinds of chemically modified silica were prepared to adsorb NO by surface modifying with vinyltriethoxysilane, acrylic acid and acryl amide respectively, and characterized by N 2 adsorption experiments, Fourier transform infrared spectroscopy, scanning electron microscopy and thermo-gravity analysis. The results showed that COOH and CONH 2 in the monomers had been grafted on the silica surface, and the pore volumes of S 1 , S 2 and S 3 decreased and exhibited the mesoporous structure; all the modified adsorbents could maintain steady under 300 °C. NO adsorption experiments were also carried out and the results suggested that the silica modified with acryl amide had the best NO adsorption capacity due to the relative large surface area and the stronger hydrogen bonds between NO molecules and the functional groups. The adsorbed NO molecules could be well desorbed by purging with N 2 so that the adsorbents could be recycled and NO resource also had the chance to be reused.
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高影响因子
ENERGY & FUELS
·
2024
·
IF 5.2
Yuwen Deng,Jijun Guo,Zaili Xiong,Wang Li,Changyang Wang,Meirong Zeng,Zhongyue Zhou,Long Zhao,Jiuzhong Yang,Wenhao Yuan,Fei Qi
The oxidation of pure n-butanal and the n-butanal/NO mixture was investigated in an atmospheric jet-stirred reactor at stoichiometric conditions and over the temperature range of 425–925 K. Mole fraction profiles of characteristic intermediates, like nitrogenous, carbonyl, and hydrocarbon intermediates were obtained using synchrotron vacuum ultraviolet photoionization mass spectrometry (SVUV–PIMS) via molecular beam sampling. A previous reported kinetic model of n-butanal oxidation was improved and a submechanism interpreting n-butanal/NOx interaction kinetics was developed and validated against experimental measurements. Results show that NO addition results in a featured temperature dependence of n-butanal reactivity similar to that of hydrocarbon fuels, i.e., inhibiting reactivity at low temperatures while promoting at intermediate temperatures. However, the presence of the n-butanal carbonyl group introduces distinct kinetic effects on this system compared to previously reported hydrocarbon/NO systems. Model analysis suggests a pronounced interaction between NO and the n-butanal carbonyl group, particularly at low temperatures where NO notably accelerates the removal of the carbonyl group, yielding large amounts of propyl radicals. This interaction results in the suppression of peroxy radical chemistry on the alkyl chain and chain-branching reactions of the propyl radical, thus decreasing the low-temperature reactivity of n-butanal. At intermediate temperatures, the influence of the carbonyl group on reactivity is not as pronounced and the increased reactivity primarily depends upon the impact of NOx on the active radical pool. For example, NOx-related chemistry accelerated the formation of OH radicals, thus facilitating fuel decomposition and the further conversion of CO to CO2. Besides, NO addition significantly affects the speciation of several products, such as methane, ethane, and formaldehyde, which was correlated to the additional competitive pathways introduced by NOx.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Jingye Zhao,Ping Li,Qi Zhang,Zhilu Ye,Yijing Wang,Jingyu Tian,Zhe Xu,Niancai Peng,Hui Ren,Xiaohui Zhang
The concentration of nitric oxide (NO) in exhaled breath is linked to respiratory diseases, requiring precise detection. Traditional two-dimensional (2D) carbon-based materials used in chemiresistive gas sensors suffer from high detection limits due to a lack of functional sites, while metal oxide sensors are limited by poor selectivity and high operating temperatures, restricting their development. Recently, metal–organic frameworks (MOFs) have emerged as an effective material for NO monitoring due to their superior selectivity; however, their inherent insulating properties hinder practical use. In this study, we synthesized Ni, Co-MOF-74-Carbon Nanotube (CNT) heterostructured nanoflowers, leveraging their bimetallic active sites and large specific surface area to enhance NO adsorption. This composite material, integrated with breathable nanofibrous membranes through physical deposition, exhibits high selection to NO, achieving a linear response range of 30 to 1000 ppb at room temperature and a limit of detection (LOD) of 18.6 ppb. This sensor can accurately detect NO levels in the exhaled breath of both healthy and diseased individuals, confirming its potential for respiratory disease diagnosis. Additionally, we developed a portable device integrating the Ni, Co-MOF-74-CNT-polyacrylonitrile (PAN) membrane, a microcontroller unit (MCU), and a Bluetooth module for real-time NO detection. The systematic design and successful validation of this portable gas sensor pave the way for future home-based real-time monitoring of airway inflammation.
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CANADIAN JOURNAL OF CHEMICAL ENGINEERING
·
2017
·Vol. 96
·期 1
·27-32
·
IF 1.356
Haiqian Zhao,Xingcun Gao,Chenghao Liu,Zhonghua Wang,Hanbing Qi
Basic rules of NO oxidation by a Fe 2+ /H 2 O 2 /AA directional decomposition system were researched based on the technical background of flue gas NO x removal. Effects of gas-liquid interfacial area, main gas, and solution parameters on NO oxidation efficiency ( η ) were analyzed. The results showed that adequate contact area was the precondition for high η by a Fe 2+ /H 2 O 2 /AA system. η decreased with the increase in NO concentration, which illustrated that this method would be efficient in oxidizing NO at a low concentration. η tended to decrease linearly with the growth in gas flow, however, the NO oxidation rate ( v ) rose with the increase in NO concentration and gas flow. η increased with the initial concentrations of H 2 O 2 and Fe 2+ , but the amplitude decreased. Controlling the initial concentrations of H 2 O 2 and Fe 2+ to achieve reasonable synergies between generation rate and consumption rate of ·OH could weaken the invalid consumption of reactants. η increased with the increase in temperature in the range 30–60 °C, but it nearly did not change with temperature after 60 °C. This oxidation technology and the traditional wet flue gas desulphurization technology exhibited temperature synergy. Under typical pH of wet desulphurization, η and H 2 O 2 consumption rate did not change obviously.
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2025
·
IF 7.7
Tongtong Cheng,Yiqi Tang,Heping Zhang,Xingqi Song,Gongcheng Xu,Ying Zhou,Xinghui Hou
SnO 2 is an n-type wide band gap (E g = 3.6 eV) metal oxide semiconductor (MOS) that has been widely studied, due to its low cost, non-toxicity and simple preparation process, and it has become the most important sensitive material for the preparation of gas sensors. However, the SnO 2 sensor still has some defects of high operating temperature and low response, which hinders its practical application. In this work, SnO 2 /SnS composites were prepared by hydrothermally growing SnS nanoparticles on the surface of electrospun hollow SnO 2 nanotubes with high porosity. Results show that the SnO 2 /SnS gas sensor based on the heterojunction has a much higher response of 375 to 50 ppm NO at 130 ℃ than that of pure SnO 2 sensor, as well as rapid response/recovery (26 s/90 s), excellent selectivity (12 times that of H 2 S), repeatability and stability (225–250 to 20 ppm NO). Its enhanced sensing property may be attributed to the synergistic effect of the formation of homologous cations heterojunction and unique micro-structure of SnO 2 /SnS composite, which could facilitate efficient charge transfer and provide more active sites (such as vacancy, point defects) for NO adsorption and reaction. This experiment provides a new idea for the development of SnO 2 gas sensors with excellent properties, which can meet the detection of toxic and harmful gas.
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高影响因子
Materials Today Bio
·
2026
·
IF 11
Shuang Liu,Zhongming Zhao,Ziyi Wang,Xianghe Pi,Weiqin Zhao,Huiju Hu,Xinmei He,Pengcheng Che,Junjie Li,Hong Sun
Developing integrated, drug-free therapeutic platforms that simultaneously address oxidative stress, immune dysregulation, and gut microbiota dysbiosis remains a significant challenge in UC management. Although hydrogels offer localized delivery advantages, their clinical versatility is frequently hindered by a reliance on exogenous drug encapsulation. To overcome this limitation, we developed a multifunctional, ROS-responsive hydrogel (ODCAS) that functions as an inherently bioactive platform. The ODCAS network is constructed via dynamic Schiff base crosslinking between ODex and thiolated arginine chitosan, further reinforced by ROS-triggered disulfide bonds leveraging. This sophisticated architecture undergoes ROS-responsive programmed degradation, driving in situ NO generation to trigger a therapeutic cascade. Specifically, the TPA-derived thiol moieties facilitate inflammation-targeted mucoadhesion via disulfide exchange with the mucosal layer, while simultaneously providing potent, direct ROS scavenging (72.21 ± 2.47% DPPH· radical scavenging). Furthermore, the metabolic byproducts of the hydrogel network provide prebiotic support to restore microbial equilibrium. In a DSS-induced murine colitis model, oral administration of ODCAS significantly attenuated disease severity, reducing the DAI by 52.08%, downregulating pro-inflammatory cytokines, and restoring both intestinal barrier integrity and microbial homeostasis. These findings highlight the ODCAS hydrogel as a robust, ROS-responsive biomaterial platform that orchestrates disulfide-mediated anchoring and an arginine-driven NO cascade for the effective management of chronic inflammatory diseases.
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高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2026
·
IF 5.9
Zhaoyan Ge,Fengni Liu,Ziwei Chen,Hao Liu,Jiang Yuan
A coating was constructed via LBL self-assembly to improve hemocompatibility. • The coating had an adjusted KSNO payload capacity, achieving a tunable NO release. • The coated film promoted the ECs, while suppressing the over-proliferation of SMCs. • The coated film showed antibacterial, antioxidant, and anti-inflammatory activities. • Biomacromolecular donor of NO was used as a monolayer for LBL for the first time. Nitric oxide (NO) releasing coating is promising for implantable medical devices due to the role of NO in the vascular system. In the study, a multilayered NO-releasing coating was constructed via layer-by-layer (LBL) self-assembly to improve the hemocompatibility of poly(ethylene terephthalate)(PET). A keratin-based NO donor (KSNO) was synthesized and used as a negatively-charged monolayer. Polyethyleneimine (PEI) acted as a positively-charged monolayer. The LBL coating has an adjusted KSNO payload capacity, achieving a tunable NO release in the presence of ascorbic acid (Asc). The coated PET film (n = 5) selectively promoted the proliferation of endothelial cells, while suppressing the excessive proliferation of smooth muscle cells. Furthermore, the coated film demonstrated excellent biocompatibility, along with antibacterial, antioxidant, and anti-inflammatory activities. To the best of our knowledge, it is the first time that a biomacromolecular donor of NO has been used as a monolayer for LBL self-assembly.
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Chem & Bio Engineering
·
2025
·Vol. 3
·期 2
·340-350
·
IF 0
Cui Yuehan,Li Fupeng,Du Yun,Zhu Xinchen,A Sigen,Cen Lian,Huang Kai,Zhao Ling,Yang Shengbing,Xi Zhenhao
Diabetic wound healing represents a highly prevalent
and economically
burdensome complication of diabetes mellitus. The healing is hampered
by two pathophysiological barriers: persistent bacterial biofilms
and impaired angiogenesis. While reactive oxygen species (ROS)-mediated
strategies are promising, their efficacy is limited by exogenous H 2 O 2 dependency and rapid oxidant decomposition.
In this study, we engineer a multifunctional nanoplatform (SNP/ZnO 2 @lipo), which synergizes potent antibacterial ability and
angiogenesis capacity. Its architecture features polyvinylpyrrolidone-modified
zinc peroxide (ZnO 2 ) cores with sodium nitroprusside (SNP)
adsorbed on their surface, which are further enveloped within cationic
phospholipid bilayers. In infected, mildly acidic microenvironments,
bacterial phospholipases and membrane instability destabilize the
lipid shell, thereby exposing the SNP/ZnO 2 core. The exposed
ZnO 2 and SNP then generate H 2 O 2 ,
Zn 2+ , Fe 2+ , and NO in situ .
The orchestrated ROS and reactive nitrogen species (RNS) cascade achieves
synergistic bactericidal efficacy through dual mechanisms: Fe 2+ -mediated Fenton reactions and NO-derived ·NO formation.
The continuous in situ production of oxidants overcomes
the need for exogenous H 2 O 2 . In vitro , the platform shows high biocompatibility, a strong antibacterial
capacity, and remarkable angiogenic potential. In diabetic murine
wound models, SNP/ZnO 2 @lipo accelerates wound healing through
concurrent clearing of infection and promoting neovascularization.
These data identify SNP/ZnO 2 @lipo as an intelligent wound
microenvironment-responsive nanoplatform that couples microbial eradication
with vascular regeneration, offering a promising strategy for treating
infected diabetic wounds.
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DOI
PubMed
INTERNATIONAL JOURNAL OF PHARMACEUTICS
·
2025
·
IF 5.2
Chensheng Ding,Nian Liu,Zhengwei Chen,Zhuolin Wu,Chun Mao,Ziyu Wu,Yuan Xie,Mimi Wan
Due to the particularity of melanoma location, traditional drug delivery methods face difficulties in penetrating skin tissue and specifically clearing melanoma cells. Here, we designed a hyaluronic acid microneedle drug delivery system loaded with nanomotors which can effectively penetrate the skin tissue and deliver the therapeutic components to melanoma and specifically remove melanoma cells. The loaded nanomotors were prepared by radical polymerization of methacryloyl modified L-arginine (MA) and L-tyrosine (MTyr), named as MA/MTyr nanomotor. The microneedle drug delivery system can use the rigid structure of microneedles to break through the skin barrier and deliver nanomotors to deep tissues. The MA endowed them with the ability to sensitively sense the highly expressed inducible nitric oxide synthase in the tumor microenvironment, so as to realize the effective targeting of melanoma in skin tissue and uptake by tumor cells. Subsequently, the MTyr can produce quinone-enriched intermediates that can induce cell death under the catalysis of tyrosinase that was specifically highly expressed in melanoma cells, and self-assembled to form micron scale fibers through intermolecular hydrogen bonding interactions, thereby inducing melanoma cells to swell. This process synergistically promoted melanoma cell death without occurring in normal cells. The experimental results of cell and animal models confirmed the good therapeutic effect of the nanomotor loaded microneedles, which provided a new therapeutic concept and strategy for the development of therapeutic methods specifically for melanoma.
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PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
·
2016
·Vol. 33
·期 3
·261-265
·
IF 2.267
Shuangbing Li,Jixiao Wang,Song Zhao,Wei Cai,Zhi Wang,Shichang Wang
The spherical silica particles in narrow size distribution with different diameters of 90 nm, 200 nm, 320 nm and 400 nm were prepared by the modified Stöber method and characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM) and dynamic light scattering (DLS). The phase composition of particles was characterized by X-ray diffraction. The results indicated that each of the silica particle samples was in amorphous state. The shear thickening fluids (STFs) comprising 53 vol.% of silica particles and 47 vol.% of polyethylene glycol with molecular weight of 200 g mol −1 (PEG200) were prepared and evaluated. The influence of size and size distribution on the critical shear rate and the intensity of shear thickening were analyzed. The STFs prepared by silica nanoparticles with a diameter of 90 nm showed the giant rheological effect with the critical shear rate of 2.51 s −1 , the largest viscosity of 45,500 Pa∙s and the yield stress of 181 kPa. The experiments and the analysis results demonstrated that the suspensions prepared by nanoparticles have high intensity of shear thickening.
研究领域:
胶体化学
·
流变学
·
纳米材料科学
·
软物质物理
·
功能材料
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高影响因子
Journal of Materials Chemistry A
·
2014
·Vol. 2
·期 29
·11065-11072
·
IF 0
Qian Zhang,Ying Zhou,Fang Wang,Fan Dong,Wei Li,Haimin Li,Greta R. Patzke
Elemental photocatalysts have recently been proposed as interesting materials to be used as alternatives to conventional semiconductor compounds. In this study, we demonstrate that not only elements with semiconducting properties are photocatalytically active by introducing semimetallic bismuth for the photooxidation of NO. Black Bi films were prepared via an electrochemical deposition approach. Both density functional theory (DFT) calculations and temperature dependence electrical resistivity measurements pointed out that the obtained films exhibited semimetallic behavior. The Bi films were easily oxidized upon exposure to air. However, electrochemical reduction of the surface amorphous oxide layer led to a more than 4-fold enhancement of the photocurrent density of the Bi films. The detection of hydroxyl radicals with electron spin resonance (ESR) investigations further confirmed the photogeneration of electrons and holes. A 37.7% removal ratio of NO over Bi films was observed under UV light irradiation with no significant reduction of photocatalytic activity after five cycles. Given that the conduction and valence bands of semimetallic Bi overlap, the associated excitation processes are more complex in comparison with semiconductor photocatalysts, thereby indicating a different photocatalytic mechanism. The present study points out new directions for developing semimetallic photocatalysts.
研究领域:
材料科学
·
环境催化
·
物理化学
·
表面科学
·
无机功能材料
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2019
·
IF 3.131
Xiaohai Li,Fanyu Meng,Shule Zhang,Mingjia Zhang,Yiqing Zeng,Qin Zhong
CrO x was loaded on a different amount of polyethylene glycol modified TiO 2 (CrO x /yPEG-TiO 2 ) by impregnation method, successfully utilized in NO oxidation. The structure-property relationships of the catalysts were explored through different characterization techniques including XRD, BET, Raman, XPS, H 2 -TPR, O 2 -TPD, NO-TPD and in situ DRIFTS. The results pointed out that the polyethylene glycol modification could enhance the interaction between CrO x with TiO 2 . Among these CrO x /yPEG-TiO 2 (y = 0, 30, 50, 80) catalysts, the CrO x /50PEG-TiO 2 had the strongest interaction between CrO x with TiO 2 , which resulted in more chemical adsorption oxygen. Meanwhile, CrO x /50PEG-TiO 2 had a certain amount of Cr 6+ . It exhibited the highest catalytic activity due to the synergy between CrO x and chemical adsorption oxygen, which reached 55% at the temperature of 350 °C. Moreover, the CrO x /50PEG-TiO 2 still exhibited wide activity temperature windows of 225–425 °C and good stability.
研究领域:
催化化学
·
环境化学
·
材料科学
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高影响因子
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