ChemistrySelect
·
2023
·Vol. 8
·期 34
·e202301948
·
IF 2.1
Hai-Bo Wu,Xian-Tai Zhou,Xiao-Wu Zhou,Yan-Xiong Fang
Graphical Benzoic acid has been proved to be an efficient catalyst for the ring-opening polymerization of ϵ-caprolactone under mild conditions. A monomer-activated ring-opening polymerization mechanism mediated by benzoic acid was proposed. It is expected to realize the one-step preparing of poly (ϵ-caprolactone) through the direct aerobic oxidation of cyclohexanone. The development of a feasible industrial method for poly(ϵ-caprolactone) (PCL) preparation is great of significant and challenging. The bulk ring-opening polymerization of ϵ-caprolactone (ϵ-CL) using various organic acid catalysts and benzyl alcohol (BnOH) as the initiator was developed. Benzoic acid (BA) has been proved to be an efficient catalyst for the ROP of ϵ-CL under mild conditions. The conversion of ϵ-CL to PCL was 84.7 % under the optimized reaction conditions, with number-average molecular weight ( M n ) and dispersity (PDI) of 7700 g/mol and 1.25, respectively. Moreover, a monomer-activated ring-opening polymerization mechanism mediated by benzoic acid was proposed. Overall, this work is expected to provide a feasible industrial method for the preparation of PCL using benzoic acid as organocatalyst.
研究领域:
高分子化学
·
有机催化
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Chemistry B
·
2025
·
IF 5.7
Zi Fu,Yan Zhou,Ziyi Liu,Zhe Chen,Qiang Fu,Shiqun Lin,Rongping Dai,Huade Zheng
Pathological myopia, characterized by excessive axial elongation, posterior staphyloma (PS) and retinal-choroidal degeneration underlies sight-threatening conditions such as myopic traction maculopathy (MTM) and macular atrophy. Macular buckling (MB) surgery has demonstrated significant efficacy in managing MTM-associated pathologies, including macular schisis, macular holes, and macular retinal detachment. However, its widespread clinical adoption remains limited due to suboptimal material properties and geometrical design constraints of existing buckling devices. Advancements in imaging modalities-such as spectral-domain optical coherence tomography (SD-OCT), swept-source OCT (SS-OCT), ultrawidefield fundus imaging, and three-dimensional magnetic resonance imaging (3D-MRI)-have substantially enhanced the understanding and evaluation of MTM biomechanics. The future development of MB may lie in identifying superior biomaterials and creating customized buckling devices tailored to individual ocular morphology. Here, we developed a photo-curable polycaprolactone (PCL)-based non-isocyanate polyurethane acrylate (NIPUA) resin (PCL-NIPUA) for one-piece J-shaped 3D-printed MB devices. Structural characterization via Nuclear Magnetic Resonance (NMR), Fourier Transform Infrared Spectroscopy (FTIR), and Mass Spectrometry (MS) confirmed successful synthesis. Photocuring kinetics under 465 nm visible light achieved an optimal storage modulus within 82 s, coupled with minimal curing shrinkage (7.2%). By tuning flexible PCL segments, the material exhibited a tensile strength of 25 MPa and elongation at break of 32%, balancing strength and elasticity. The resin demonstrated environmental stability (water contact angle: 72°; water absorption: 8.8%; thermal decomposition: 420°C) and exceptional biocompatibility (hemolysis rate <0.5%; cell viability >97%). Liquid crystal display (LCD) 3D printing produced cost-effective MB devices that provided stable scleral indentation in rabbit models, with few complications, and no pathological structural changes in the optic nerve and retina，showing good biocompatibility and safety. This work establishes PCL-NIPUA as a synergistic platform combining green chemistry, rapid photocuring, mechanical adaptability, and biosafety, offering a clinically translatable solution for customized 3D-printed implants in MB surgery.
研究领域:
眼科
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生物材料
·
组织工程
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转化医学
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生物医学工程
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眼底病学
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高分子医学材料
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2024
·
IF 8.2
Binghai Lv,Zhenyan Zhang,Bingfeng Chen,Siqi Yu,Minglong Song,Yitian Yu,Tao Lu,Liwei Sun,Haifeng Qian
The application of pesticides increases crop yields but affects the structure and function of the soil microbial community. Halogens are common functional modification groups in chemical compounds, and innovative pesticides have been developed on the basis of these groups. However, the effects of different halogen substituents on soil microorganisms remain unclear. This study investigated the effects of three pyrethroid pesticides (deltamethrin, cypermethrin, and cyfluthrin) on the soil microbiota. Our results revealed that all these pesticides significantly reduced the stability of the bacterial communities and decreased bacterial diversity at high concentrations. Compared with deltamethrin (Br − ) and cypermethrin (Cl − ), low concentrations (0.5 mg/kg) of cyfluthrin (F − ) increased soil bacterial diversity by 23.14 % and increased the potential for nitrogen fixation by 2.00 % and nitrification by 3.39 %, thus making it a relatively eco-friendly option. Our findings provide new insights into the potential ecological effects of halogenated pyrethroid pesticides on soil ecosystems .
研究领域:
环境科学
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微生物学
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土壤学
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生态毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
·
2021
·Vol. 37
·期 12
·1-12
·
IF 3.312
Zhao Zhenzhen,Liu Chao,Xu Qianqian,Ahmad Shahbaz,Zhang Haiyang,Pang Yu,Aikemu Abudumukeyiti,Liu Yang,Yan Hai
A promising bacterial strain for biodegrading dibutyl phthalate (DBP) was successfully isolated from activated sludge and characterized as a potential novel Microbacterium sp. USTB-Y based on 16S rRNA sequence analysis and whole genome average nucleotide identity (ANI). Initial DBP of 50 mg/L could be completely biodegraded by USTB-Y both in mineral salt medium and in DBP artificially contaminated soil within 12 h at the optimal culture conditions of pH 7.5 and 30 ℃, which indicates that USTB-Y has a strong ability in DBP biodegradation. Phthalic acid (PA) was identified as the end-product of DBP biodegraded by USTB-Y using GC/MS. The draft genome of USTB-Y was sequenced by Illumina NovaSeq and 29 and 188 genes encoding for putative esterase/carboxylesterase and hydrolase/alpha/beta hydrolase were annotated based on NR (non redundant protein sequence database) analysis, respectively. Gene3781 and gene3780 from strain USTB-Y showed 100% identity with dpeH and mpeH from Microbacterium sp. PAE-1. But no phthalate catabolic gene ( pht ) cluster was found in the genome of strain USTB-Y. The results in the present study are valuable for obtaining a more holistic understanding on diverse genetic mechanisms of PAEs biodegrading Microbacterium sp. strains.
研究领域:
环境微生物学
·
基因组学
✓ 已验证
DOI
PubMed
高影响因子
MACROMOLECULAR RESEARCH
·
2017
·Vol. 25
·期 11
·1070-1075
·
IF 1.405
Wu Dan,Lv Yin,Guo Rui,Li Jiahui,Habadati Aerman,Lu Bowen,Wang Heyun,Wei Zhong
To evaluate the effects of different alcohols (primary, secondary, and two different tertiary alcohols) as initiators on the structure of polycaprolactone (PCL) in ring-opening polymerization (ROP), four experiments were conducted in toluene with tin(II) 2-ethylhexanoate (Sn(Oct) 2 ) as the catalyst. The kinetics of ε -caprolactone ( ε -CL) ROP at different temperatures and monomer concentrations were studied with n -butanol as the initiator and Sn(Oct) 2 as the catalyst. The kinetic plot of ln(M 0 /M t ) vs. time ( t ) seems a linear, which indicates that the propagation rate is in the first order with respect to monomer concentration. When the reaction temperature increased, the reaction rate and the final relative maximum monomer conversions also increased. The molecular weight of PCL initially increased and then decreased as monomer conversion increased. This behavior can be attributed to the high viscosity of the system, which affected monomer diffusion and polymer chain propagation. In addition, prolonging reaction time caused inter-/intramolecular transesterification. However, when monomer concentration decreased, the reaction rate decreased. The actual activation energy of Sn(Oct) 2 -catalyzed ROP of ε -CL in toluene was -75 kJ/mol.
研究领域:
高分子化学
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材料科学
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有机催化
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化学反应工程
✓ 已验证
DOI
高影响因子
JOURNAL OF WUHAN UNIVERSITY OF TECHNOLOGY-MATERIALS SCIENCE EDITION
·
2018
·Vol. 33
·期 1
·233-241
·
IF 0.524
Cai Qi,Huang Jiemin,Weng Rui,Liu Shichen
In order to prepare hydrophobic waterborne polyurethane coatings with better performances, the silicon-containing waterborne polyurethane (SiWPU) with functional chain extender hydroxyethyl acrylate (HEA) was prepared first, and then a series of silicon&fluorine-containing polyurethane/acrylate (FSiPUA) emulsions were obtained with flourine containing acrylic monomer by seed emulsion polymerization, introducing micro-nano SiO 2 into FSiPUA emulsion to make the final hybrid emulsion. The properties of SiWPU, FSiPUA and SiO 2 /FSiPUA were investigated by fourier transform infrared spectra (FTIR), transmission electron microscope (TEM), Scanning Electron Microscope (SEM) and some other analytical methods. The results revealed that FSiPUA emulsion particles possessed composite core-shell structure and FSiPUA films with suitable ratio performed better than SiWPU films in hardness, water resistance and solvent resistance. The SiO 2 /FSiPUA films with micro-nano dual roughness structure showed a water contact angle of 136° with good resistance to acid and alkali.
研究领域:
材料科学
·
表面化学
✓ 已验证
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2024
·Vol. 48
·期 7
·3221-3231
·
IF 2.7
Yafei Shi,Haiyue Wang,Qiao Zhou,RongRong Zheng,Liying Guo
Six dual active site ionic liquid catalysts were prepared by using triethylenediamine-grafted 1-bromotetradecane as a cation and coordinating with different organic anions. The structures and properties of the catalysts were characterized using Fourier transform infrared spectroscopy (FT-IR), nuclear magnetic resonance (NMR) spectroscopy, and thermogravimetric analysis (TGA). The synthesis of poly(isosorbide carbonates) (PICs) via the transesterification polycondensation of dimethyl carbonate (DMC) and isosorbide (ISB) catalyzed by a cation and anion was studied. A single factor experiment was used to investigate optimal process parameters. FT-IR, NMR, TGA, and differential scanning calorimetry (DSC) were adopted to characterize the structures and properties of PICs. The results showed that under the same process parameters, the catalyst using imidazole as an anion had the best catalytic performance. Under optimal process conditions, the conversion of ISB reached 98.82%, the weight average molecular weight of the PIC reached 28 840 g mol−1, and the glass transition temperature (Tg) of the PIC was 149 °C.
研究领域:
材料化学
·
高分子化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF POLYMER RESEARCH
·
2024
·Vol. 32
·期 1
·1-13
·
IF 2.6
Zhang Xian,Jiang Shuai,Guo Jianming,Xin Zhong
The stretchable, biodegradable, thermos-responsive, biocompatible and novel poly(1,3-propylene sebacate)-co-poly(glycerol sebacate) polyurethanes (PPGSU), based on poly(glycerol sebacate) (PGS) and poly(1,3-propylene sebacate) (PPS), were synthesized using simple solvent-based two-step method. The comprehensively properties of PPGSU, including the chemical structure, crystalline structure, thermal stability, mechanical performance, water absorption, degradation behavior, drug release behavior, temperature-responsive shape memory effect, as well as biocompatibility were investigated in detail. The impact of the different ratio of PPS and PGS on the properties of final PPGSU product was also studied. The introduction of PPS in the poly(glycerol sebacate urethance) (PGSU) system could increase the glass transition temperature ( T g ) and stretchability. The PPGSU polymers showed adjustable tensile strength ranging from 0.5 MPa to 1.3 MPa, as well as the degradable rate and shape memory effect. Furthermore, these elastomers exhibited promising in vitro biocompatibility with adult mouse fibroblasts L929 cells, indicative of their potential for medical applications. Additionally, the possible potential application of biodegradable PPGSU elastomers in the field of drug delivery were examined. Overall, this research offers new perspectives on the development of biomaterials with tailored properties for medical applications.
研究领域:
材料科学
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生物医学工程
·
生物材料学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2021
·Vol. 139
·期 16
·51988
·
IF 3.125
Ye-xi Zhou,Qing-xia Yuan,Shu-ling Gong
The high molecular weight polyacrylate self-emulsifying emulsion with 20% hydroxyl monomer and 50% solid content was prepared. Waterborne polyester was used to modify the acrylate resin. Besides acrylic acid (AA) and methacrylic acid (MAA), poly(ethylene glycol) methyl ether methacrylate (PEGMEMA) was also used as functional monomer to stabilize the polymerization process and improve the properties of the emulsion. The effects of the amount of waterborne polyester (WP), ammonium persulfate (APS), poly(ethylene glycol) methyl ether methacrylate (PEGMEMA), methacrylic acid (MAA)/acrylic acid (AA) monomer ratio, butyl acrylate (BA)/styrene (St) monomer ratio on the molecular weight, particle size, viscosity, storage stability, and cured film properties of the polyacrylate emulsion were investigated. The average molecular weight of the modified polyacrylate was up to about 2.5 × 10 4 g mol −1 . The emulsion remained stable after 6 months at room temperature. Transmission electron microscope (TEM) images showed that the latex particles had core-shell structure. The films cured with melamine formaldehyde (MF) resin showed excellent water resistance, adhesion, and hardness.
研究领域:
材料科学
·
高分子化学
✓ 已验证
产品关联
DOI
高影响因子
PROGRESS IN ORGANIC COATINGS
·
2020
·
IF 4.469
Yang Xu,Jing Luo,Xiaoya Liu,Ren Liu
Epoxy acrylate resins modified by polyurethane with excellent mechanical properties play a crucial role in UV-curable coatings, but the high viscosity limits their further applications in 3D printing, electronic packaging material. In this work, a series of polyurethane modified epoxy acrylate resins containing various ε-caprolactone unit content were successfully synthesized to reduce the viscosity of polyurethane modified epoxy acrylate resins. The chemical structure and molecular weight of the prepared resins were characterized by Fourier transform infrared spectroscopy (FTIR), proton nuclear magnetic resonance spectroscopy ( 1 H NMR) and gel permeation chromatography (GPC), respectively. The influences of ε-caprolactone unit on the viscosity of resins and double bond conversion of cured films were studied. The dynamic thermomechanical properties, mechanical properties, thermal stability and basic properties of UV curable coatings were also evaluated. The results show that the viscosity of resins is reduced by two orders of magnitude. As the ε-caprolactone unit content increased, the adhesive force increased from 0B to 5B according to ASTM D3359, while the glass transition temperatures (Tg) of films and pencil hardness were slightly lower than those of the conventional polyurethane modified epoxy acrylate resins. In summary the introduction of ε-caprolactone unit in the side chain enables the preparation of polyurethane modified epoxy acrylate resin with ultralow viscosity as well as a more comprehensive adhesive and impact force performance.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
WOOD SCIENCE AND TECHNOLOGY
·
2014
·Vol. 48
·期 6
·1241-1255
·
IF 1.873
Liu Wendi,Chen Tingting,Wen Xiaoyun,Qiu Renhui,Zhang Xincong
Bamboo fibers were mechanically extracted from raw green bamboos by crushing, rolling, and combing techniques with 1,4-butanediol as a solvent. The morphology of the bamboo fibers thus obtained was analyzed. The bamboo fibers were treated with isocyanatoethyl methacrylate (IEM) in the presence of dibutyltin dilaurate as a catalyst, to improve the interfacial adhesion between the fibers and unsaturated polyester (UPE) resins. The bamboo fibers reinforced UPE composites were prepared by hand lay-up compression molding. FTIR, XPS, and NMR analyses indicated that the IEM was covalently bonded onto the bamboo fibers via carbamate linkages. The IEM treatments significantly increased the tensile strength, flexural strength, flexural modulus, and water resistance of the resulting composites and yet decreased the impact strength of the composites. The SEM images of the tensile-fractured surfaces of the IEM-treated bamboo fibers–UPE composites revealed that the fiber treatments markedly improved the interfacial adhesion between the bamboo fibers and UPE resins.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY
·
2015
·Vol. 117
·期 8
·1171-1178
·
IF 1.812
Shangde Sun,Bingxue Hu,Fanfan Song,Yanlan Bi
Glyceryl ferulates (GMF + GDF, combination of glyceryl monoferulate and glyceryl diferulate), and feruloylated acylglycerols (FMAG + FDAG, combination of feruloylated monoacylglycerols, and feruloylated diacylglycerols) are hydrophilic and lipophilic derivatives of ferulic acid (FA), which can be used as antioxidants and UV absorbers in food and other fields. In this study, the effect of ionic liquids (ILs) and organic solvents on the enzymatic transesterification of ethyl ferulate (EF) with monostearin was investigated. The effects of reaction time, temperature, and enzyme load on EF conversion and reaction selectivity were also evaluated and optimized using response surface methodology. Among ILs tested, high EF conversion (98.4 ± 0.5%), and reaction selectivity for GMF + GDF (0.81) were obtained in [Emim]TF 2 N; and for organic solvents tested, EF conversion (72.7 ± 1.5%) and reaction selectivity (0.75) were achieved in n-hexane. Results also showed that, compared with n-hexane, [Emim]TF 2 N can improve the selective synthesis of GMF + GDF, and [Emim]TF 2 N also shows significant protection on the enzyme inactivation at high temperature (90°C). The activation energies (Ea) of hydrolysis to form GMF + GDF and transesterification to form FMAG + FDAG were 51.98 and 43.49 kJ/mol in [Emim]TF 2 N, 72.35, and 53.11 kJ/mol in n-hexane, respectively. , , and in [Emim]TF 2 N were 0.01, 0.19 mol/L, and 4.13 × 10 −4 mol/(L · min), respectively. Practical applications: In this work, FMAG + FDAG and GMF + GDF were prepared by enzymatic transesterification of EF with monostearin. During the reaction, the competitive reaction of the hydrolysis of monostearin to form hydrophilic GMF + GDF and the transesterification of monostearin and EF to form lipophilic FMAG + FDAG take place in parallel. The effect of ionic liquids (ILs) and organic solvents on the competitive reaction was investigated. Compared with organic solvent (n-hexane), IL ([Emim]TF 2 N) is apt to the formation of hydrophilic GMF + GDF; and [Emim]TF 2 N shows remarkably protective effect on the inactivation of enzyme at high temperature up to 90°C than that (65°C) of n-hexane. This study can give information about the influence of different reaction media on the enzymatic transesterification and reaction selectivity. Enzymatic transesterification of ethyl ferulate (EF) with monostearin to produce hydrophilic glyceryl monoferulate (GMF)+glyceryl diferulate (GDF) and lipophilic feruloylated monoacylglycerols (FMAG)+feruloylated diacylglycerols (FDAG) in ionic liquids or organic solvents.
研究领域:
食品科学
·
生物化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）