DYES AND PIGMENTS
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2025
·
IF 4.2
Xin Lin,Fang-Fang Shen,Ren-Jie Song
In this study, two novel fluorescent probes, H 1 /G and H 2 /G, were constructed using two alkyl-substituted cucurbit[6]urils (CB[6]s), H 1 and H 2 , and a cationic dye guest, G. The G molecules were encapsulated within the cavities of CB[6] hosts, forming 1:1 host–guest complexes. While free G molecules exhibited negligible fluorescence in solution, the inclusion complexes demonstrated a strong fluorescence signal (618 nm). The detection limits for glutamic acid (Glu) recognition by the two probes were as low as 2.98 × 10 −7 M and 4.20 × 10 −7 M, respectively. Notably, although the two modified CB[6]s differed by only a single substituent, their resulting probes demonstrated different degrees of amino acid recognition ability. The H 2 /G probe was capable of recognizing both Glu and lysine (Lys), while the H 1 /G probe detected only Glu. By employing structurally modified CB[6]s as hosts and constructing CB[6]-based fluorescent probes capable of selectively recognizing non-aromatic amino acids, this study paves the way for the biological applications of CB[6]-based supramolecular host–guest systems.
研究领域:
超分子化学
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分析化学
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生物有机化学
·
荧光传感
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产品关联
DOI
高影响因子
Inorganic Chemistry Frontiers
·
2017
·Vol. 5
·期 2
·438-445
·
IF 4.036
Qilong Gao,Jun Chen,Qiang Li,Ji Zhang,Zhao Zhai,Shantao Zhang,Ranbo Yu,Xianran Xing
Photo-Fenton catalysis with high-efficiency is required for the resolution of environmental pollution. Here, the Prussian blue analogue BiFe(CN)6·4H2O with a narrow bandgap (1.63 eV) shows excellent visible light catalysis to decompose organic dyes and tetracycline. The microrod and nanoplate morphologies were successfully synthesized by simple precipitation with different additives. The nanoplates of BiFe(CN)6·4H2O show excellent phono-Fenton catalytic activity meaning that RhB can be decomposed within 6 min in the presence of H2O2. BiFe(CN)6·4H2O exhibits a layered structure, which consists of FeC6 and BiN6 coordination polyhedra. The zero field cooling indicated that BiFe(CN)6·4H2O has an antiferromagnetic order at low temperatures. Furthermore, the stability of the BiFe(CN)6·4H2O catalyst is very good, which has been investigated by various characterizations. The mechanism of the excellent catalysis is related to the crucial role of H2O2, which inhibits the recombination of the electron–hole pair and drives the photo-Fenton reaction. Therefore, to treat the wastewater by photo-Fenton catalysis, the present component of BiFe(CN)6·4H2O is a promising catalyst candidate.
研究领域:
环境科学
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材料科学
·
化学
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DOI
高影响因子
CARBOHYDRATE RESEARCH
·
2017
·
IF 2.096
Louis Patrick Conway,Fang Fang Liu,Qian Li,Josef Voglmeir
Galactokinases are a class of enzymes which belong to the GHMP (galactokinase, homoserine kinase, mevalonate kinase , and phosphomevalonate kinase) superfamily and catalyse the phosphorylation of galactose in the first step of the Leloir pathway . Here we report the discovery of three enzymes from Shewanella woodyi which have been classified as galactokinases based on sequence similarity. However, each of these enzymes show little to no significant activity towards galactose and instead exhibit a strong preference for glucose. Furthermore, in contrast to the usual galactose-1-phosphate product of the galactokinase-catalysed reaction, these enzymes produce glucose-6-phosphate. This radical change in enzyme functionality is postulated to be linked to the mutation of a glycine residue which is conserved in all other sequenced galactokinases.
研究领域:
生物化学
·
微生物学
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产品关联
DOI
PubMed
高影响因子
OPTICAL MATERIALS
·
2022
·
IF 3.754
Tian Zhang,Zhiwen Gan,Shujun Zhen,Yongmei Hu,Xiaoli Hu
Due to the well-known side effects on human health caused by 6-Mercaptopurine (6-MP), it is necessary to develop a simple to operate method for determination of 6-MP. In this work, a simple and easy ratiometric fluorescence probe was fabricated based on two kind of quantum dots with different emission. The probe was composed of blue emission carbon dots (CDs) and yellow emission Zn-doped CdTe quantum dots (ZnCdTe QDs) capped with GSH. The fluorescence intensity of ZnCdTe QDs could be selectively quenched by 6-MP based on fluorescence resonance energy transfer (FRET). At the same time, the fluorescence intensity of CDs basically stayed constant, and the fluorescence intensity ratio ( F 445 / F 565 ) showed a linear response to the concentration of 6-MP. The designed probe of ZnCdTe QDs/CDs displayed a wide and comparable detection range from 1.0 to 100.0 μmol L −1 , and the detection limit reached 0.46 μmol L −1 . Furthermore, the method has been realized for monitoring the concentration of 6-MP in human serum samples.
研究领域:
分析化学
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生物医学
·
材料科学
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DOI
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
·
2017
·
IF 1.753
Kai Chen,Jing Xu,Sheng-Chao Qiu,Yuan Wang,Min-Dong Chen,Yun-Qian Zhang,Xin Xiao,Zhu Tao
We investigated the interactions in an inverted cucurbit[6]uril ( i Q[6]) with a series of 1, ω -alkyldimins and their supramolecular assemblies in the presence of the tetrachlorozincate anion ([ZnCl 4 ] 2− ) structure directing agent . i Q[6] forms an outer surface interaction with [ZnCl 4 ] 2− to form different i Q[6]/[ZnCl 4 ] 2− -based supramolecular assemblies with different length 1,ω-alkyldimins. Interestingly, most 1,ω-alkyldimins were not visible in crystals structures in the presence of concentrated HCl. The porous i Q[6]/[ZnCl 4 ] 2− -based supramolecular assemblies could be used as materials for adsorbing volatile compounds .
研究领域:
化学
·
材料科学
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产品关联
DOI
高影响因子
MICROCHIMICA ACTA
·
2017
·Vol. 185
·期 1
·1-6
·
IF 4.58
Liu Xing-Pei,Xie Xing-Li,Wei Yu-Ping,Mao Chang-jie,Chen Jing-Shuai,Niu He-Lin,Song Ji-Ming,Jin Bao-Kang
A film of perovskite-type LaFeO 3 nanoparticles (NPs) was deposited on fluorine-doped tin oxide (FTO) conducting glass via dipping-lifting and calcination. Scanning electron microscopy shows that the NPs are evenly distributed on the surface of the glass. The modified glass was further coated with antibody against human interleukin 6 (IL-6) to result in a photoelectrochemical immunosensor for IL-6. The well-established photoelectrochemical immunoassay has a linear current response in the range of 0.1 pg·mL −1 to 0.1 μg·mL −1 and a detection limit as low as 33 fg·mL −1 . Schematic of a novel photoelectochemical immunoassay for the measurement of IL-6 based on perovskite-type LaFeO3 nanoparticles. The immunoassay had a higher sensitivity and may also be applied to other bioanalysis and environment monitoring.
研究领域:
生物化学
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分析化学
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生物传感器
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免疫分析
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产品关联
DOI
PubMed
高影响因子
International Journal of Inflammation
·
2014
·
IF 0
Hang Yang,Haili Qi,Jingli Ren,Jing Cui,Zhenfeng Li,Helge L. Waldum,Guanglin Cui
Nuclear factor-kappaB (NF-κB)/interleukin (IL-6) pathway links chronic inflammation to colitis associated cancer (CAC). In this study, we examined the dynamic temporal changes of the NF-κB/IL-6 pathway during the procession of experimental CAC mouse model. Mice were sacrificed after induction for 14, 16, 18, and 22 weeks for the examination of tumor burden, inflammation degree, and protein level of NF-κB and IL-6 in bowel tissues. The results showed that tumor burden and inflammation severity in the bowels were gradually increased over the observed time-points. The expressions of IL-6 and NF-κB proteins were gradually increased after induction of dysplastic lesions over times. These data provide new information on the dynamic temporal changes of NF-κB/IL-6 pathway in relation to CAC development that may be relevant in the design of future investigations of therapeutic interventions to effectively target CAC processes.
研究领域:
分子生物学
·
肿瘤学
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免疫学
✓ 已验证
DOI
PubMed
POLYMER ENGINEERING AND SCIENCE
·
2017
·Vol. 57
·期 12
·1301-1310
·
IF 1.449
Xianming Zhang,Menghan Sun,Wenxing Chen
This study examines the selective dispersion of nano-SiO 2 in polystyrene (PS) and polyamide 6 (PA6) blends. With the coupling assistance of 3-methacryloylpropyl trimethoxysilane (MPS), nano-SiO 2 surfaces are grafted with PS chains of different molecular weights (SiO 2 –MPS–PS) or reactive random copolymer of styrene (St) and 3-isopropenyl-α,α′-dimethylbenzene isocyanate (TMI) to produce SiO 2 –MPS–P(St–co–TMI). The isocyanate groups of the reactive copolymer can react with the terminal group of the PA6 to form a graft copolymer, which helps in controlling the location of nano-SiO 2 between the PS and PA6 phases. Field-emission scanning electron microscopy imaging combined with the rheological method was used to investigate the location and dispersion of nano-SiO 2 , as well as the morphology of the PS/PA6 blends, at low nano-SiO 2 loading. Compared with pristine SiO 2 , the modified SiO 2 with different chain lengths adjusted the PA6 phase with refined size and narrow size distribution because of the strong interaction with both phases. The SiO 2 –MPS–PS with appropriate length is the most effective. The use of nano-SiO 2 along with the reactive compatibilizer provides synergistic effects for improving the compatibilization of PS/PA6 blends. POLYM. ENG. SCI., 57:1301–1310, 2017. © 2017 Society of Plastics Engineers
研究领域:
材料科学
·
高分子化学
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产品关联
DOI
高影响因子
RSC Advances
·
2025
·Vol. 15
·期 5
·3331-3338
·
IF 4.6
Dinghua Yu,Jianqiang Wang,Guowei Wang
Silane coupling agents play an indispensable role in improving interfacial adhesion of composite materials, but their interaction mechanism is often unclear. This article combines experiments and theoretical calculations to reveal the importance of hydrogen bonds between silane coupling agents and the matrix polyamide 6 in improving the mechanical properties of composite materials. Firstly, glycine bridged silane (GBSilane) was synthesized and the structure was confirmed by FT-IR, 1H NMR and HRMS. Secondly, with glass fiber treated using GBSilane as a filler, the mechanical properties of glass fiber/PA6 composite materials were studied. Compared with untreated glass fiber/PA6 composites, under the optimal treatment concentration of 1.5%, the tensile strength of glass fiber/PA6 composites treated with 3-aminopropyl triethoxysilane (APTES) and GBSilane increased by 41% and 67%, respectively, and the notch impact strength increased by 55% and 96.5%, respectively. Lastly, density functional theory (DFT) calculations revealed that stronger hydrogen bonds have formed between GBSilane and PA6 than APTES, which have induced the stronger PA6–GBSilane binding energy of 58.20 kJ mol−1. By comparison, the binding energy of PA6–APTES is only 30.91 kJ mol−1. These results demonstrated that the as-synthesized GBSilane could improve the mechanical properties of PA6 composites through an enhanced hydrogen bonding mechanism.
研究领域:
材料科学
·
化学工程
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2018
·Vol. 135
·期 21
·46302
·
IF 1.901
Wenqi Wang,Jie Ying,Jikui Wang
In this article, a novel method has been successfully developed to prepare the anionic polyamide 6/polystyrene (APA6/PS) blends. The macroactivator P(St- co -IEM) was synthesized by the free radical polymerization of 2-isocyanatoethyl methacrylate and styrene (St), then the graft copolymer of PS and APA6 (PS- g -APA6) can be obtained by the anionic polymerization of ɛ-caprolactam activated by the macroactivator P(St- co -IEM). The X-ray diffraction analysis, differential scanning calorimetry, scanning electron microscopy analysis, contact angle measurement, water absorption measurement, molau test, thermogravimetric analysis, and mechanical properties test were performed separately to study the effects of P(St- co -IEM) on crystallinity, morphology, water resistance, thermal stability, and mechanical properties. The results indicate the synthesis of macroactivator can promote the formation of the γ-phase. Moreover, it can improve the interfacial compatibility, water resistance, thermal stability, and toughness. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018 , 135 , 46302.
研究领域:
高分子化学
·
材料科学
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产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Xiaomeng Li,Beibei Hu,Lijie Ma,Yuechan Shi,Yongshuai Jing,Zhongqiu Li,Zhiwei Li,Shiguo Sun
Growth hormone-releasing hexapeptide (GHRP-6) is a kind of stimulant, which can be illegally used in athletic performance enhancement during sports. The accurate and sensitive detection of GHRP-6 is crucial for ensuring fair competition. Electrochemical sensors achieve quantitative analysis by monitoring the changes in electrochemical signals induced by target analytes. In this study, we developed an electrochemical sensor based on voltammetry to detect GHRP-6, providing a novel and advanced analytical methodology for its detection. The GHRP-6 was used as templates, phenol as polymer monomers, and MWCNTs as signal amplification materials, to build a detection method based on molecularly imprinted electrochemistry (MIEC). The fabricated sensor displayed rapid binding kinetics due to the location of all imprinting cavities on the polymer’s surface. This method displayed a linear relationship in the concentration range of 0.1 ∼ 100 ng/mL, featuring a detection limit of 1.21 pg/mL (S/N = 3). The percent recovery of GHRP-6 was 96.0 ∼ 103.2 % with the RSD in the range of 1.49 ∼ 5.56 %. The reproducibility test of the method resulted in an RSD of 3.19 %. Compared to the normal detection method, this technique shows more reproducibility and stability in real human serum samples. This study introduces an advanced, simple, and practical detection method for GHRP-6 in clinical samples.
研究领域:
分析化学
·
生物医学工程
·
运动科学
✓ 已验证
产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2018
·
IF 4.439
Wei Tao,Juan Li
In this paper, nitrogenous bases adenine (A), guanine (G), cytosine (C), and uracil (U), were used to tailor the hydrogen-bonded network of melamine cyanurate (MCA) and were noted as A-MCA, G-MCA, C-MCA, U-MCA, respectively. The results showed that the size, morphology and thermal behavior of MCA are regulated by base due to the formation of hydrogen bonds between them. These modified MCAs were used to improve the flame retardancy of polyamide 6 (PA6) which was evaluated by using the limiting oxygen index (LOI) and the vertical burning (UL-94) test, etc. The results showed that the PA6 sample containing 9 wt% C-MCA achieves the UL-94 V-0 rating and has a LOI value of 30.7%, while the other samples with equal amounts of MCA only pass the UL-94 V-2 rating. The flame retardant mechanism was studied, and the results reveal that C-MCA with smaller size has greater contact area with PA6 which helps to catalyze the decomposition of PA6; Thus the PA6/C-MCA releases more NH 3 , CO 2 etc., and produces more droplets than others, which dilutes combustible gas and takes away heat to make the samples extinguish.
研究领域:
材料科学
·
高分子化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）