JOURNAL OF FOOD SCIENCE
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2024
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IF 3.2
Mibin Lin,Jia Sha,Zhonghao Zhu,Penghui Ye,Kai Zhao,Kaijun Xiao
Metal–organic frameworks (MOFs) have great potential for the adsorption of minor molecular alcohols in the vapor phase. However, the drawbacks of powdered MOFs, including low recyclability and problematic separation, limit their application in fermented wine. Chitosan (CS) is a low-cost, eco-friendly, moldable matrix used in the food industry. In this study, a novel CS@ZIF-8 adsorbent with excellent microporous surface area was successfully synthesized by incorporating hydrophobic ZIF-8 into CS. The results showed that CS@ZIF-8 beads had a high adsorption affinity for methanol at a Zn 2+ /2-methylimidazole molar ratio of 1:5. The adsorption mechanism of methanol on CS@ZIF-8 beads was systematically studied by X-ray photoelectron spectroscopy, isotherms, and kinetics. The Langmuir model calculated the maximum adsorption of methanol to 56.8 mg/g. Adsorption kinetics are consistent with pseudo-second-order models. Furthermore, CS@ZIF-8 beads presented excellent recyclability for removing methanol for five consecutive cycles. It could treat 60 bed volumes of Chinese yellow wine in column filtration experiments to make the concentration below 50 mg/L. In summary, the highly efficient CS@ZIF-8 adsorbent has great potential for methanol adsorption from fermented wines. Practical Application Methanol will exhibit adverse symptoms such as weakness and headaches after it is ingested. Therefore, methanol control is an important safety factor in the production of fermented wine. The adsorption method is recognized as a widely used technique due to its high efficiency and selectivity. The CS@ZIF-8 adsorbent synthesized in this paper provides a new idea for methanol removal.
研究领域:
食品科学
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材料科学
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产品关联
DOI
PubMed
高影响因子
CURRENT CANCER DRUG TARGETS
·
2024
·Vol. 25
·期 3
·294-305
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IF 2.3
Yiping Zheng,Jianfeng Cai,Qiuhong Ji,Luanmei Liu,Kaijun Liao,Lie Dong,Jie Gao,Yinghui Huang
BackgroundLung cancer remains a major global health threat due to its complex microenvironment, particularly the role of neutrophils, which are crucial for tumor development and immune evasion mechanisms. This study aimed to delve into the impact of lung cancer cell-conditioned media on neutrophil functions and their potential implications for lung cancer progression.MethodsEmploying in vitro experimental models, this study has analyzed the effects of lung cancer cell-conditioned media on neutrophil IL-8 and IFN-γ secretion, apoptosis, PD-L1 expression, and T-cell proliferation by using techniques, such as ELISA, flow cytometry, immunofluorescence, and CFSE proliferation assay. The roles of IL-8/PD-L1 in regulating neutrophil functions were further explored using inhibitors for IL-8 and PD-L1.ResultsLung cancer cell lines were found to secrete higher levels of IL-8 compared to normal lung epithelial cells. The conditioned media from lung cancer cells significantly reduced apoptosis in neutrophils, increased PD-L1 expression, and suppressed T-cell proliferation and IFN-γ secretion. These effects were partially reversed in the presence of IL-8 inhibitors in Tumor Tissue Culture Supernatants (TTCS), while being further enhanced by IL-8. Both apoptosis and PD-L1 expression in neutrophils demonstrated dose-dependency to TTCS. Additionally, CFSE proliferation assay results further confirmed the inhibitory effect of lung cancer cell-conditioned media on T-cell proliferation.ConclusionThis study has revealed lung cancer cell-conditioned media to modulate neutrophil functions through regulating factors, such as IL-8, thereby affecting immune regulation and tumor progression in the lung cancer microenvironment.
研究领域:
肿瘤学
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免疫学
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细胞生物学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF SOLID STATE CHEMISTRY
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2021
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IF 3.498
Jiaying Pei,Zhongsheng Chen,Youqun Wang,Bo Xiao,Zhibin Zhang,Xiaohong Cao,Yunhai Liu
In this study, a 10%Fe-ZIF-8-300-PO 4 adsorbent was synthesized and its adsorption performance for U(VI) was investigated comprehensively. It was found that after a series of operations such as Fe doping, thermal activation and phosphorylation, the adsorption performance for U(VI) can be significantly improved on the basis of maintaining the skeleton characteristics of ZIF-8. The results showed that the optimal Fe-doping amount and thermal activation temperature was 10% and 300°C, respectively. The adsorption of U(VI) on 10%Fe-ZIF-8-300-PO 4 reached equilibrium within 60 min, and conformed to pseudo-second-order kinetic equation. Furthermore, a maximum saturated adsorption capacity of 691.83 mg/g was achieved. The above results demonstrated that 10%Fe-ZIF-8-300-PO 4 may be used to efficiently remove U(VI) from uranium-containing radioactive waste water.
研究领域:
环境科学
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材料科学
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产品关联
DOI
高影响因子
ADVANCED ENGINEERING MATERIALS
·
2023
·Vol. 25
·期 11
·2201710
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IF 3.6
Zihan Tian,Zhaoping Hou,Xinhe Yang,Liangliang Liu,Wanggang Zhang
Due to the wider bandgap and low electron discharge capacity, the zeolitic imidazolate framework (ZIF-8) shows low photocatalytic performance compared with conventional semiconductor materials. To enhance the photocatalytic activity of ZIF-8, the ZIF-8@AgNWs composite is synthesized via the in situ growth method using silver nanowires (AgNWs) as the photo-enhanced material. The obtained ZIF-8@AgNWs exhibit the fully encapsulated shell-core structure of ZIF-8-AgNWs. The UV−vis diffuse reflectance spectroscopy (DRS) analysis shows that the addition of AgNWs leads to a significant increase in light absorption of the ZIF-8@AgNWs composite, and the bandgap of the ZIF-8@AgNWs is 2.9 eV, with a significant decrease compared to pure ZIF-8 (4.96 eV). The ZIF-8@AgNWs-2 achieves the best photocatalytic activity for methylene blue (MB) degradation. Its degradation efficiency reaches 94%, and its apparent rate constant is 0.04371 min −1 . Herein, a novel strategy for the MOF-based photocatalytic materials with higher photocatalytic activity is provided.
研究领域:
材料科学
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环境科学
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产品关联
DOI
高影响因子
JOURNAL OF ENVIRONMENTAL MANAGEMENT
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2021
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IF 6.789
Wenpeng Li,Qingping Wang,Xiaoying Jin,Nasreen Islam Khan,Gary Owens,Zuliang Chen
Wastewater generated during mining remains a significant source of antimony pollution, because techniques to quickly and efficiently remove antimony from wastewater do not exist. In this study, zeolitic imidazolate framework-8 (ZIF-8), a specific type of Metal Organic Frameworks (MOFs), was successfully used to remove trace levels (1 mg L −1 ) of Sb(V) with a high removal efficiency when the ZIF-8 dose was 0.5 g L −1 . Scanning electron microscopy-X-ray energy dispersive spectrometry (SEM-EDS) indicated that Sb(V) was adsorbed onto the ZIF-8surface. The powder X-ray diffraction (XRD) pattern of ZIF-8 before and after adsorption of Sb(V) indicated that ZIF-8 was successfully synthesized, and remained structurally stable after Sb(V) was adsorbed. Fourier transform infrared (FTIR) and X-ray photoelectron spectroscopy (XPS) both suggested complexation of zinc on ZIF-8 with Sb(V), where removal of Sb(V) by ZIF-8 followed the Langmuir adsorption isotherm with pseudo second-order kinetics. Thus, a possible removal mechanism was proposed which involved Sb(V) complexing with the zinc hydroxyl groups on ZIF-8 (Zn–OH–Sb). Practically, ZIF-8, could remove 78.6% of Sb(V) from a mining wastewater containing 20 μg L −1 Sb(V). Furthermore, ZIF-8 could be remain active after repeated uses and could still remove and 42.3% of Sb(V) from wastewater containing 1 mg L −1 ) Sb(V) even when the ZIF-8 was reused five time. This indicated that ZIF-8 had potential for practical removal of Sb(V) from mining wastewaters.
研究领域:
环境科学
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水处理
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材料科学
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DOI
PubMed
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
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2023
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IF 13.6
Mina Liu,Lei Zhang,Rongrong Yang,Haiyang Cui,Yanan Li,Xiujuan Li,He Huang
Suspended microorganisms often experience diminished efficacy in the bioremediation of polycyclic aromatic hydrocarbons (PAHs). In this study, the potential of zeolite imidazolate framework-8 (ZIF-8) and the eco-friendly modifier citric acid (CA) was harnessed to generate a biomimetic mineralized protective shell on the surface of Bacillus subtilis ZL09-26, resulting in an enhanced capability for PAH degradation. This investigation encompassed the integrated responses of B. subtilis ZL09-26 to ZIF-8 and ZIF-8-CA at both cellular and proteomic levels. The amalgamation of ZIF-8 and CA not only stimulated the growth and bolstered the cell viability of B. subtilis ZL09-26, but also counteracted the toxic effects of phenanthrene (PHE) stress. Remarkably, the bioremediation prowess of B. subtilis ZL09-26@ZIF-8-CA surpassed that of ZL09-26@ZIF-8 and ZL09-26, achieving a PHE removal rate of 94.14% within 6 days. After undergoing five cycles, ZL09-26@ZIF-8-CA demonstrated an enduring PHE removal rate exceeding 83.31%. A complex interplay of various metabolic pathways orchestrated cellular responses, enhancing PHE transport and degradation. These pathways encompassed direct PHE biodegradation, central carbon metabolism, oxidative phosphorylation, purine metabolism, and aminoacyl-tRNA biosynthesis. This study not only extends the potential applications of biomineralized organisms but also offers alternative strategies for effective contaminant management.
研究领域:
环境科学
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微生物学
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生物技术
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材料科学
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产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2024
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IF 13.3
Shuhui Hu,Lin-Lin Yang,Chang Yan,Yanan Xiao,Zijing Jin,Xiuhai Gan,Bo Zhang,Wenneng Wu
Environmental stimulus-responsive controlled-release nanopesticides have the ability to adapt to the specific microenvironment of pathogen outbreaks, which can improve pesticide utilization efficiency. A pH and redox dual-stimuli responsively controlled release system (ZIF-8@Hex@Fe/GA) using zeolitic imidazolate framework-8 (ZIF-8) as the support and metal-phenol complex (Fe-GA) as the capping agent was constructed to deliver hexaconazole (Hex) for management of Phomopsis sp. The ZIF-8@Hex@Fe/GA composite demonstrated a high loading capacity and effectively improved the light stability of Hex. The hydroxyl groups present in the composite facilitate its diffusion on kiwifruit leaves, improving wettability. Additionally, the large specific surface area of ZIF-8@Hex@Fe/GA provides resilience against rainwater scouring. This innovative system intelligently responds to the acidic and oxidizing conditions associated with Phomopsis sp. infections, ensuring targeted and controlled release of Hex. Bioactivity assessments revealed that ZIF-8@Hex@Fe/GA exhibited protective effects of 84.16 ± 3.37 % and 80.77 ± 2.08 % on kiwifruit fruits and leaves at a concentration of 100 mg/L, outperforming Hex emulsifiable concentrate (Hex EC) by 21.34 % and 25.39 %, respectively. The acute toxicity of ZIF-8@Hex@Fe/GA to zebrafish was reduced 9-fold compared to Hex EC. Furthermore, ZIF-8@Hex@Fe/GA showed high safety for HEK293 cells, with a cell survival rate of 81.59 ± 2.11 % after 72 h of 10 mg/L treatment, whereas the cell survival rate for Hex TC, treatment was only 1.79 ± 1.32 % after 72 h. In conclusion, ZIF-8@Hex@Fe/GA demonstrates significant potential for targeted pesticide delivery and environmental protection.
研究领域:
植物病理学
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环境科学
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材料科学
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产品关联
DOI
高影响因子
Journal of CO2 Utilization
·
2018
·
IF 5.503
Zhengfeng Huang,Peimei Dong,Yanzhao Zhang,Xiaoxiao Nie,Xiya Wang,Xiwen Zhang
A strategy of coupling a photocatalyst with a high CO 2 adsorption capacity material was proposed in order to integrate CO 2 capture and photoreduction processes into a single system. TiO 2 and ZIF-8 were selected for their high photoactivity and CO 2 adsorption capacity respectively. We employed a facile in-situ growth strategy to inlay ZIF-8 into the TiO 2 film grid. X-ray diffraction and scanning electron microscopy revealed that ZIF-8 was successfully prepared and inlaid into the TiO 2 film. X-ray photoelectron spectroscopy and photoluminescence spectra suggested that the TiO 2 and ZIF-8 were coupled by chemical bonding. The ZIF-8 decorated TiO 2 film exhibited excellent CO 2 capture capacity and showed remarkably enhanced yield for reducing CO 2 to CO and CH 4 when compared with pure TiO 2 film. The probable mechanism of the photoreduction process is also discussed.
研究领域:
材料科学
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环境科学
·
化学工程
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DOI
高影响因子
ACS Applied Nano Materials
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2022
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IF 6.14
Seojin Jung,Seokhee Chang,Na-Eun Kim,Seong-O Choi,Yoon-Jae Song,Yue Yuan,Jooyoun Kim
A feasible strategy of on-demand drug delivery for the treatment of dermal inflammation under low-pH conditions is proposed, employing zeolitic imidazolate framework-8 (ZIF-8) as a pH-responsive nanoparticle and curcumin (CCM) as a model drug. To overcome the low bioavailability of topically treated drug, a microneedle (MN) form is used to incorporate CCM and ZIF-8. Taking advantage of the fact that ZIF-8 degrades under acidic conditions, CCM is embedded in porous ZIF-8 nanoparticles such that CCM is released when ZIF-8 comes into contact with an acidic dermal fluid at the inflammation site, and this CCM-encapsulated ZIF-8 (CCMZIF) is incorporated into water-dissolvable poly(vinyl pyrrolidone) MN. The ZIF-8 shows a high loading capacity (∼40.5%) of CCM through chemical bonding and physical adsorption. From in vitro tests with both a buffered solution and porcine skin, CCM from the CCMZIF MN is released in a higher amount at pH 5.0 than at pH 7.4, demonstrating the capability of the pH-responsive release of the drug when needed at inflammatory sites. The analytical investigation conducted here reveals that an acidic environment triggers the structural degradation of ZIF-8, allowing the release of the chemically bonded CCM. Cytotoxicity and stability tests demonstrate the good biocompatibility and bioavailability of ZIF-8. This study highlights the analytical discussion of the encapsulation and release mechanism of CCM in a ZIF-8-implemented MN drug delivery platform. The results demonstrate an advanced on-demand therapeutic strategy for skin disorder treatment.
研究领域:
药剂学
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生物材料学
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皮肤病学
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DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
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2024
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IF 2.7
Wei Li,Linghao Wang,Menghao Lin,Li Chen,Xinjuan Zeng,Lichun Dong,Cailong Zhou
Mixed matrix membranes (MMMs) have emerged as a promising solution for the treatment of dye wastewater. A key challenge in advancing MMMs is how to effectively integrate two nanofillers with distinct advantages to mitigate the limitations of single-nanofiller systems. In this study, we present a binary nanofiller strategy, utilizing metal–organic frameworks (MOFs) and covalent organic frameworks (COFs), to fabricate polyvinylidene fluoride (PVDF) based MMMs. By systematically adjusting the mass ratio of ZIF-8 MOF and TFB-BD(Me) 2 COF, the separation efficiency of membranes for dyes with different charges, capitalizing on the molecular sieving properties of MOFs and the superior compatibility of COFs was evaluated. The optimized membrane demonstrated a rejection of 91.66% for Congo red (CR), along with a water permeance of 641.9 L m −2 h −1 bar −1 . This work represents a novel attempt in the design of binary-nanofiller MMMs, offering new insights into the synergistic effects of hybrid nanofillers in membrane technology.
研究领域:
材料科学
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环境工程
✓ 已验证
产品关联
DOI
高影响因子
Materials
·
2018
·Vol. 11
·期 1
·159
·
IF 2.467
Liqing Li,Xiancheng Ma,Ruofei Chen,Chunhao Wang,Mingming Lu
Nitrogen-doped porous carbon (ZC) is prepared by modification with ammonia for increasing the specific surface area and surface polarity after carbonization of zeolite imidazole framework-8 (ZIF-8). The structure and properties of these ZCs were characterized by Transmission electron microscopy, X-ray diffraction, N2sorption, X-ray photoelectron spectroscopy and Fourier transform infrared spectroscopy. Through static adsorption tests of these carbons, the sample obtained at 600 °C was selected as an excellent adsorbent, which exhibited an excellent acetone capacity of 417.2 mg g−1(25 °C) with a very large surface area and high-level nitrogen doping (13.55%). The microporosity, surface area and N-containing groups of the materials, pyrrolic-N, pyridinic-N, and oxidized-N groups in particular, were found to be the determining factors for acetone adsorption by means of molecular simulation with density functional theory. These findings indicate that N-doped microporous carbon materials are potential promising adsorbents for acetone.
研究领域:
材料科学
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环境科学
✓ 已验证
DOI
高影响因子
DYES AND PIGMENTS
·
2022
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IF 5.122
Heng Wu,Jie Zhao,Xi Nan Yang,Dan Yang,Li Xia Chen,Carl Redshaw,Li Guo Yang,Zhu Tao,Xin Xiao
A system comprising cucurbit[8]uril (Q[8]) and a fluorescent molecule (E)-1-(2-hydroxyethyl)-4-(4-hydroxystyryl)pyridin-1-ium bromide (HPy) has been utilized to construct a fluorescent probe that is capable of detecting the pesticide tricyclazole (TC). A variety of techniques including 1 H NMR spectroscopy together with fluorescence experiments have been employed to investigate the host-guest properties of the Q[8]/HPy system in aqueous solution. Results indicate that the system forms the stable2:1 inclusion complex HPy 2 @Q[8], and that this inclusion complex imparts fluorescent quenching on HPy. The addition of a number of pesticides was found to have no obvious effect on the fluorescence, however on addition of tricycazole (TC), the fluorescence intensity underwent a dramatic enhancement. The linear relationship between the fluorescence intensity and the concentration of TC allowed for the facile detection of TC concentration in aqueous target solutions as well as in agricultural products. The detection limit was found to be 3.70 × 10 −8 mol L −1 .
研究领域:
分析化学
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环境科学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）