INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2020
·
IF 4.939
Wenyu He,Jinhui Wei,Ting Huang,Enren Zhang
For practical applications of microbial fuel cells (MFCs), 5H-dibenz [b,f] azepine-5-carboxamide (Carbamazepine, CBZ) was used as the organic precursor for the synthesis of catalysts composed of Fe–N–C complexes (named as Fe-CBZ-Cats) through a sacrificial support method. Characterizations by SEM, XPS and TEM-EDS elemental mapping show that the synthesized Fe-CBZ-Cats have porous structure and uniformly dispersed Fe/N/C complex centers which could play key roles in effective ORR . Linear scanning voltammetry (LSV) measurements show that the synthesized Fe-CBZ-Cats exhibits ORR activity comparable to commercial Pt/C catalysts under the same catalyst loading (2 mg cm −2 ). The maximum power density produced by cathode-limiting MFCs with Fe-CBZ-Cats air cathodes was 431 ± 23 μW cm −2 , higher than those in the control MFCs with Pt/C air cathodes (403 ± 13 μW cm −2 ) and activated carbon air cathodes (296 ± 24 μW cm −2 ). In addition, the toxicity tolerance of the synthesized Fe-CBZ-Cats is much higher than Pt/C.
研究领域:
环境科学
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电化学
·
生物工程
✓ 已验证
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Yuan Gao,Jing Gao,Zhibin Zhang,Yue Wu,Xiaolin Sun,Fuhua Zhao,Yuan Zhang,Depeng Song,Wenyan Si,Qing Zhao,Xun Yuan,Jianfei Wu
Sulfide solid-state electrolytes have garnered considerable attention owing to their notable ionic conductivity and mechanical properties. However, achieving an electrolyte characterized by both high ionic conductivity and a stable interface between the electrode and electrolyte remains challenging, impeding its widespread application. In this work, we present a novel sulfide solid-state electrolyte, Li3.04P0.96Zn0.04S3.92F0.08, prepared through a solid-phase reaction, and explore its usage in all-solid-state lithium sulfur batteries (ASSLSBs). The findings reveal that the Zn, F co-doped solid-state electrolyte exhibits an ionic conductivity of 1.23 × 10–3 S cm–1 and a low activation energy (Ea) of 9.8 kJ mol–1 at room temperature, illustrating the aliovalent co-doping’s facilitation of Li-ion migration. Furthermore, benefiting from the formation of a LiF-rich interfacial layer between the electrolyte and the Li metal anode, the Li/Li3.04P0.96Zn0.04S3.92F0.08/Li symmetrical cell exhibits critical current densities (CCDs) of up to 1 mA cm–2 and maintains excellent cycling stability. Finally, the assembled ASSLSBs exhibit an initial discharge capacity of 1295.7 mAh g–1 at a rate of 0.05 C and at room temperature. The cell maintains a capacity retention of 70.5% for more than 600 cycles at a high rate of 2 C, representing a substantial improvement compared to the cell with Li3PS4. This work provides a new idea for the design of solid-state electrolytes and ASSLSBs.
研究领域:
材料科学
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电化学
·
能源存储
✓ 已验证
DOI
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2017
·
IF 4.9
Mi Deng,Yongming Wu,Chao Xu,Yuanxiang Jin,Xiaoli He,Jinbao Wan,Xiaoling Yu,Hongmin Rao,Wenqing Tu
A Chinese perfluorooctane sulfonate (PFOS) substitute frequently detected in the environment, 6:2 chlorinated polyfluorinated ether sulfonate (F-53B), has a similar structure to PFOS and it is proposed to cause thyroid dysfunction. To further confirm this hypothesis, the effects of F-53B on the thyroid endocrine system and underlying mechanisms were investigated in vitro and in vivo using rat pituitary GH3 cells and developing zebrafish, respectively. In GH3 cells, F-53B enhanced cell proliferation in a dose-dependent manner, indicative of thyroid receptor agonistic activity. In zebrafish larvae, F-53B exposure induced significant developmental inhibition and increased thyroxine (T 4 ) but not 3,5,3′-triiodothyronine (T 3 ) levels accompanied by a decrease in thyroglobulin (TG) protein and transcript levels of most genes involved in the hypothalamic-pituitary-thyroid (HPT) axis. Interestingly, T 4 levels remained significantly increased while TG protein and gene transcription levels were markedly upregulated after depuration. Molecular docking studies revealed that F-53B binds to transthyretin (TTR) by forming hydrogen bonds with Lys123 and Lys115, thereby interfering with thyroid hormone homeostasis. Our collective in vitro , in vivo and in silico studies provide novel evidence that F-53B disrupts the thyroid endocrine system at environmentally relevant concentrations, which cannot be recovered after depuration. Given the persistence of F-53B in the environment, the long-term consequences of thyroid hormone disruption by this chemical warrant further investigation.
研究领域:
环境科学
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毒理学
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内分泌学
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分子生物学
✓ 已验证
DOI
PubMed
高影响因子
BIOORGANIC CHEMISTRY
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2020
·
IF 4.831
Shiyang Zhou,Gangliang Huang
In this study, a series of novel 7 H -benzo [ c ] [1,3] dioxolo [4, 5- f ] chromen-7-one derivatives were obtained by structural modification of the lead compounds with Fissitungfine B. A total 15 compounds were designed, synthesized and evaluated as inhibitors of tumor. These target compounds have the novel chemical structures that named three six-membered rings including one lactone six-membered ring. In vitro assay, the results showed that the target compounds have a broad spectrum and strong of anti-tumor activity. Such as the target compound 4n to MCF-7 was IC 50 = 0.35 ± 0.01 μM, to A-549 was IC 50 = 0.37 ± 0.01 μM, to Hela was IC 50 = 0.56 ± 0.02 μM, to MDC-803 was IC 50 = 0.53 ± 0.02 μM and COLO-205 was IC 50 = 0.50 ± 0.02 μM in vitro . At the same time, in vivo anti-tumor activity assay results showed that the target compounds had a good inhibitory effect on tumor growth. Among them, the target compound 4n had the best anti-tumor activity, it could inhibit tumor growth well at a low dose. The target compound 4n could be used as a candidate drug for further research and development, in order to be used as early as application in the clinical treatment of tumors.
研究领域:
药物化学
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肿瘤学
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有机合成
✓ 已验证
DOI
PubMed
高影响因子
ENDOCRINE
·
2016
·Vol. 56
·期 1
·73-81
·
IF 3.279
Zhu Jing-Jie,Huang Jun-Shang,Wang Ting,Ji Jun,Hou Ai-Jun,Wang He-Yao
Adipose tissue is not only a lipid storage site, but also a well-known endocrine organ. Dysfunction of adipose tissue is associated with irregular lipid metabolism, ectopic lipid accumulation and insulin resistance. It is proposed that modulating on adipose tissue is a reasonable way to ameliorate glucose and lipid metabolism. (±)-sanggenol F (SGF, purity >98.5%) was synthesized as a racemic mixture of natural (+)-sanggenol F. In this study, SGF was found to promote adipocyte differentiation, enhance insulin sensitivity, and upregulate beneficial adipokines expression in 3T3-L1 cells. Furthermore, in vivo study showed that treatment with SGF for 4 weeks improved glucose metabolism, by decreasing fasting blood glucose and enhancing insulin sensitivity. It also improved lipid metabolism, with reduced serum lipid level and ameliorated hepatic steatosis in db/db mice. During the process of target finding, we found that SGF had multiple activities of protein tyrosine phosphatase 1B inhibition, peroxisome proliferator-activated receptor γ and peroxisome proliferator-activated receptor α agonism. These results showed the potential of SGF as a candidate for the therapy of type 2 diabetes.
研究领域:
药理学
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内分泌学
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代谢
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF CATALYSIS
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2020
·
IF 7.888
Lei Lei,Danlian Huang,Chen Zhang,Rui Deng,Sha Chen,Zhihao Li
As a member of the transition metal sulfide family, cobalt sulfides (CoS x ) are considered as highly-activity, cost-effectively, as well as stable electrocatalysts with huge potential for the application of water splitting. Combining experiments and theoretical calculations, we demonstrated that F dopants could activate the Co and S sites of CoS 2 in CoS 2 @NF composites prepared via one-step hydrothermal method and contribute to enhance the intrinsic electrical conductivity, achieving a significantly improved activity of water splitting. The improved surface wettability in F-doped CoS 2 @NF composites ensures rapid electrolyte penetration and accelerates migration of hydroxyl as well as oxygen release. Furthermore, the F-doped CoS 2 @NF composites exhibit remarkable electrocatalytic activity and excellent long-term operational stability for overall water splitting in alkaline and neutral media. Predominantly, our work could be explored to enhance and understand the catalytic properties of other transition metal sulfides, and be also expected for further progress achieved with other nonmetal element dopants.
研究领域:
电化学
·
材料科学
·
催化
·
能源材料
✓ 已验证
产品关联
DOI
高影响因子
Food Science & Nutrition
·
2024
·
IF 3.5
Jialing Lin,Chuanhui Zeng,Xueli Li,Qin Tang,Jing Liao,Yan Jiang,Xianchun Zeng
Heterocyclic amines (HAs) are a group of mutagenic and carcinogenic compounds produced from the processing of high-protein foods, which include 2-amino-3-methylimidazo[4, 5-f]quinoline (IQ) showing the strongest carcinogenic effect. Camels are able to digest HAs in foods, which provide rich microbial resources for the study. Thus, camel rumen and intestinal microbiota were used to degrade IQ, and the dominant microorganisms and their degradation characteristics were investigated. After three generations of culture with IQ as the sole carbon source, the highest abundance in rumen and intestinal microbes was found in the Proteobacteria phylum. The strains of third generation of the rumen contents were mainly attributed to the genera Brevundimonas and Pseudomonas , and the dominant genera in intestine were Ochrobactrum , Bacillus , and Pseudomonas . Microorganisms were further isolated and purified from the third generation cultures. These 27 strains from the rumen (L1–L27) and 23 strains from the intestine (C1–C23) were obtained. Among them, four strains with the most effective degrading abilities were as follows: L6 (28.55% of IQ degrading rate) and C1 (25.19%) belonged to the genus Ochrobactrum , L15 (23.41%) belonged to the genus Pseudomonas , and C16 (20.89%) were of the genus Bacillus . This study suggested the application of abundant microbial resources from camels' digestive tract to biodegrade foodborne toxins.
研究领域:
微生物学
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环境科学
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食品科学
·
毒理学
✓ 已验证
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2024
·
IF 4.3
Wenqing Li,Jingyue Zhang,Linhan Fan,Yun Zhao,Changyan Sun,Wenjun Li,Zhidong Chang
Aniline is an organic pollutant with carcinogenicity and teratogenicity, while F - and Hg 2+ are toxic ions that are easily soluble in water. When they are released to the environment, they will pose a threat to human health. Designing a material that can simultaneously detect three types of pollutants is of great significance. In this paper, a novel rare earth metal organic framework material (Eu-MOF) with three-dimensional structure based on 1-methylimidazole-4,5-dicarboxylic acid was synthesized for the first time through solvent thermal method. It has excellent luminescent performance and can be used as a multifunctional fluorescent probe to detect aniline, F - , and Hg 2+ based on photoinduced electron transfer, energy competitive absorption, and ion exchange mechanisms, with detection limits of 1.79 × 10 -8 , 8.13 × 10 -8 , and 8.83 × 10 -7 M, respectively. It is worth noting that Eu-MOF can detect F - and Hg 2+ in real water samples, such as lake water and green tea water, with favorable recovery rates.
研究领域:
材料科学
·
环境化学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2022
·
IF 5.895
Ya Jiang,Qingqing Jiang,Daming Fan,Mingfu Wang,Yueliang Zhao
The effect of acrolein, a lipid oxidation product, on the formation of the heterocyclic aromatic amine 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) was investigated in a chemical model containing glycine, creatinine, and glucose. Acrolein addition at 0.02–0.2 mmol increased MeIQx formation, while high levels of acrolein (>0.2 mmol) did not further increase MeIQx formation. Moreover, acrolein addition decreased the residue of glycine and creatinine but increased the residue of glucose; it also increased the formation of volatile intermediates in the MeIQx-producing chemical model. Further analysis indicated that acrolein can react with glycine, creatinine, and MeIQx to eliminate them. These results revealed that acrolein was able to contribute to MeIQx formation as a consequence of the comprehensive ability of acrolein to facilitate Strecker degradation of glycine, increase the formation of volatile intermediates, and react with glycine, creatinine, and MeIQx. In addition, the oxidation of minced salmon increased the content of MeIQx in the roasted salmon patties, further supporting the potential contribution role of lipid oxidation products in the formation of MeIQx.
研究领域:
食品科学
·
化学
·
毒理学
✓ 已验证
DOI
高影响因子
Journal of Materials Chemistry C
·
2024
·
IF 5.7
Mingjun Zhao,Panting Wang,Chongyun Shao,Weichang Li,Danping Chen,Wei Chen
Novel transparent luminescent glass ceramics with the ability to generate the line emission of Eu2+ ions were successfully prepared. First, Eu2+-doped barium–aluminum–borate oxyfluoride glasses were prepared by high-temperature melting in a reducing atmosphere, and then transparent glass ceramics were obtained by crystallization heat treatment. Fluorescence spectroscopy showed that Eu2+ exhibited only broadband luminescence (FWHM ≈ 136 nm) of the 4f65d1 → 4f7 transition in the glasses. However, after heat treatment, a 359 nm line emission (FWHM ≈ 2.8 nm) from the 4f7 → 4f7 transition of Eu2+ appeared in the glass ceramics. To explore the mechanism of transformation of the optical transition of Eu2+ from 4f65d1 → 4f7 to 4f7 → 4f7, the glasses and glass ceramics were analyzed by fluorescence spectroscopy, X-ray diffraction (XRD), Raman spectroscopy, and electron paramagnetic resonance (EPR) spectroscopy measurements. The results showed that the alteration in the optical transition of Eu2+ was a result of the Eu2+ ions entering the Ba2+ sites with weak crystal field strength in BaAlBO3F2 (BABF) crystals from the strong crystal field strength glass phase.
研究领域:
材料科学
·
光学
✓ 已验证
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2016
·
IF 3.014
Guang-Xin Xiang,Guo-Jun Wang,Zhi-Jun Zhang,He Feng,Jing-Tai Zhao,Jiao Wang,Xin-Yuan Sun,Ri-Hua Mao,Yong Wang
The uniform 1D nano-rods of RE 3+ doped Ln 7 O 6 F 9 ( Ln = Y and Lu; RE = Pr, Sm and Eu) were synthesized through a facile two-step hydrothermal method without extra fluorine source followed by post-heat treatment. The phase formation, morphologies, as well as photoluminescence properties of the materials were investigated. The precursor composition was determined to be Ln (OH) 1.69 F 1.31 using the Fourier transform infrared spectrum (FT-IR), thermal gravimetric and differential scanning calorimetry (TG-DSC). The average lengths of Y 7 O 6 F 9 and Lu 7 O 6 F 9 were about 6.8 and 7.9 μm, respectively, with the average width of about 650 nm. It was interesting that the tip of the nano-rods exhibits a straight line and divergent umbrella shaped bifurcation for Y 7 O 6 F 9 and Lu 7 O 6 F 9 , respectively. Upon ultraviolet excitation, Pr 3+ , Sm 3+ and Eu 3+ ions in Ln 7 O 6 F 9 showed blue, orange and red emissions originating from their characteristic f-f transitions. In addition, the 4 f 1 5 d 1 → 4 f 2 band emissions (340–450 nm) as well as typical 4 f 2 → 4 f 2 line emissions (450–700 nm) of Pr 3+ were observed in Pr 3+ -doped Ln 7 O 6 F 9 . For Sm 3+ -doped Ln 7 O 6 F 9 , only the typical f - f transitions of Sm 3+ were observed with the absence of charge transfer (CT) band. However, the broad excitation bands at 255 nm attributing to the charge transfer transition of Eu 3+ (i.e. O 2− → Eu 3+ CT) were observed in Eu 3+ -doped Ln 7 O 6 F 9 .
研究领域:
材料科学
·
纳米技术
·
光学
·
化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2024
·
IF 3.8
Furong Tang,Ting Zou,Ziyi Wang,Juan Zhang
A novel fluorinated triazine-based covalent organic frameworks (F-CTFs) was designed and synthesized by using melamine and 2,3,5,6-tetrafluoroterephthalaldehydeas as organic ligands for selective pipette tip solid-phase extraction (PT-SPE) of amphiphilic fluoroquinolones (FQs). The competitive adsorption experiment and mechanism study were carried out and verified that this F-CTFs possesses favorable adsorption affinity for FQs. The abundant fluorine affinity sites endowed the F-CTFs high selectivity to FQs extraction through F-F interactions. The adsorption capacity of F-CTFs can reach up to 109.1 mg g −1 for enrofloxacin. The detailed characterization of the F-CTFs adsorbent involved the application of various techniques to examine its morphology and structure. Under optimized conditions, a method combining F-CTF-based PT-SPE with high-performance liquid chromatography (PT-SPE-HPLC) was established, which exhibited a broad linear range, excellent precision, and an impressively low limit of detection, and could be used for the determination of six FQs in milk, with LODs as low as 0.0010 μg mL −1 . The recovery rates during extraction varied between 92.1% and 111.4%, exhibiting RSDs below 6.8% at different spiked concentrations.
研究领域:
分析化学
·
食品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）