ENDOCRINE
·
2016
·Vol. 56
·期 1
·73-81
·
IF 3.279
Zhu Jing-Jie,Huang Jun-Shang,Wang Ting,Ji Jun,Hou Ai-Jun,Wang He-Yao
Adipose tissue is not only a lipid storage site, but also a well-known endocrine organ. Dysfunction of adipose tissue is associated with irregular lipid metabolism, ectopic lipid accumulation and insulin resistance. It is proposed that modulating on adipose tissue is a reasonable way to ameliorate glucose and lipid metabolism. (±)-sanggenol F (SGF, purity >98.5%) was synthesized as a racemic mixture of natural (+)-sanggenol F. In this study, SGF was found to promote adipocyte differentiation, enhance insulin sensitivity, and upregulate beneficial adipokines expression in 3T3-L1 cells. Furthermore, in vivo study showed that treatment with SGF for 4 weeks improved glucose metabolism, by decreasing fasting blood glucose and enhancing insulin sensitivity. It also improved lipid metabolism, with reduced serum lipid level and ameliorated hepatic steatosis in db/db mice. During the process of target finding, we found that SGF had multiple activities of protein tyrosine phosphatase 1B inhibition, peroxisome proliferator-activated receptor γ and peroxisome proliferator-activated receptor α agonism. These results showed the potential of SGF as a candidate for the therapy of type 2 diabetes.
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JOURNAL OF HAZARDOUS MATERIALS
·
2015
·
IF 4.529
Bo Yang,Chaojin Jiang,Gang Yu,Qiongfang Zhuo,Shubo Deng,Jinhua Wu,Hong Zhang
The novel F-doped Ti/SnO 2 electrode prepared by SnF 4 as the single-source precursor was used for electrochemical degradation of aqueous perfluorooctanoic acid (PFOA). Higher oxidation reactivity and significantly longer service life were achieved for Ti/SnO 2 –F electrode than Ti/SnO 2 – X ( X = Cl, Br, I, or Sb) electrode, which could decomposed over 99% of PFOA (50 mL of 100 mg L −1 ) within 30-min electrolysis. The property of Ti/SnO 2 –F electrode and its electrooxidation mechanism were investigated by XRD, SEM–EDX, EIS, LSV, and interfacial resistance measurements. We propose that the similar ionic radii of F and O as well as strong electronegativity of F caused its electrochemical stability with high oxygen evolution potential (OEP) and smooth surface to generate weakly adsorbed OH. The preparation conditions of electrode were also optimized including F doping amount, calcination temperature, and dip coating times, which revealed the formation process of electrode. Additionally, the major mineralization product, F − , and low concentration of shorter chain perfluorocarboxylic acids (PFCAs) were detected in solution. So the reaction pathway of PFOA electrooxidation was proposed by intermediate analysis. These results demonstrate that Ti/SnO 2 –F electrode is promising for highly efficient treatment of PFOA in wastewater.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2013
·
IF 3.535
Yankun Jia,Zhixiong Li,Wenying Shi
The fabrication of the ordered colorimetric molecule/layered double hydroxide (LDH) ultrathin films (UTFs) by the LBL deposition technique was reported, and demonstrates their application as a colorimetric chemosensor for F − . The structural and surface morphology studies show that the UTF is continuous and uniform with stacking order in the normal direction of the substrate. The LDH nanoparticles isolate Alizarin complexone (AC) molecules from each other. The AC/LDH UTFs display a stepwise and regular growth of upon increasing deposition cycles proved by UV–vis absorption and a periodical layered structure perpendicular to the substrates with a thickness of 5.96–6.28 nm per bilayer observed by X-ray diffraction and scanning electron microscopy. Moreover, the (AC/LDH) 20 UTF displays an excellent behavior as colorimetric chemosensor for F − with a low detection limit (12.9 μM), good regeneration and reversibility , high stability (light and storage stability) as well as selectivity. In addition, the mechanism of measurement–regeneration cycle for the colorimetric chemosensor indicates F − enters/departs from the AC/LDH UTF giving rise to reversible change in chemical composition and surface morphology of the UTF. Therefore, this work provides new opportunities for fabrication and application of chromophore/LDH UTFs as colorimetric chemosensors.
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CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Zhaorui Zhang,Jiahao Liu,Haiying Du,Xufei Zhao,Haoming Sun,Minghui Yang,Jinkui Chu
A surface functional group modulation method was used to regulate the NO 2 sensing performance of the Ti 3 C 2 T x sensor. The monolayer Ti 3 C 2 T x MXene was synthesized from Ti 3 AlC 2 (MAX phase) by hydrofluoric acid (HF) etching. Ar/O 2 hybrid plasma treatment was used to regulate the ratio of hydroxyl and fluorine functional groups (OH/ F) in the Ti 3 C 2 T x surface structure. Room-temperature (RH) NO 2 sensor based on modified Ti 3 C 2 T x was fabricated by the dip coating method. The modified Ti 3 C 2 T x sensor has a higher gas response (45.31 %) to 50 ppm NO 2 compared with the untreated Ti 3 C 2 T x sensor which shows more excellent sensitivity and linearity with the NO 2 concentration of 5–50 ppm. It is due to that the presence of the hydroxyl potential on the Ti 3 C 2 T x surface well amplifies the electronic surface activity of Ti 3 C 2 T x . Concurrently, the modified electronic structure augments the adsorption propensity of Ti 3 C 2 T x for O 2 (2.26 |eV|) and NO 2 (3.24 |eV|), thereby improving the NO 2 sensing capability of the Ti 3 C 2 T x sensor. These results demonstrate that Ti 3 C 2 T x with a high ratio of OH/ F functional groups has great potential in developing high-performance room temperature NO 2 sensors.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Shumail Farhan,Asif Hassan Raza,Long Li,Songyu Yang,Yan Wu
Comprehending the catalytic reaction implementation for heterostructure photocatalysts is crucial by scrutinizing the spatial separation and transfer process of photoexcited charges at nanoscale junctions. Herein, we fabricated the F-doped TiO 2 /ZnIn 2 S 4 -based S-scheme heterostructure using a direct liquid-assembly method. The optimum hydrogen evolution rate (HER) of ∼ 1.58 mmol g –1 h –1 was acquired for 30-F 3 T@ZIS, which was about 15 and 2 times superior to the pristine F-doped TiO 2 and ZnIn 2 S 4 , respectively. The interaction between F-doped TiO 2 and ZnIn 2 S 4 facilitated the charge transfer from ZIS to F 3 T which was confirmed through XPS. UV–vis spectroscopy and Mott–Schottky validated that F-doped TiO 2 and ZnIn 2 S 4 retain the suitable energy band alignment for the S-scheme heterostructure. In situ, KPFM and EPR analysis revealed that F-doped TiO 2 and ZnIn 2 S 4 possess a spontaneous photoelectrochemical response, and their junction significantly improves the internal electric field by separating photoexcited charge carriers. This work provides a conclusive experimental and theoretical validation for an internal electric field and charge flow direction in non-noble-metal-based heterostructure photocatalysts.
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CERAMICS INTERNATIONAL
·
2025
·
IF 5.6
Xu Zhang,Shuting Li,Jiyang Zhang,Jihong Liu,Chaoyang Huang,Jiapeng Zhu,Guixiao Jia,Shengli An
CeO 2 is a promising electrolyte for intermediate-temperature solid oxide fuel cells (IT-SOFCs). Studies have found that F-doping improves its ionic conductivity, but the underlying mechanisms remain unclear. Therefore, this study employs a DFT+U method to calculate geometrical and electronic structures and oxygen ion migrations of Gd-, Ca- and F-dopings co-doped CeO 2 . The calculated results are verified by our experiment. DFT calculations find that oxygen vacancies (V) are easily formed at next-neighboring sites near the F - ions, different with the case of Gd- and Ca-doped CeO 2 . Gd-, Ca- and F-dopings strengthen Ce-O bonds, inconstant with the result from the reported experimental hypothesis for the F-doping. The F-doping restrains the change of Ce 4+ to Ce 3+ . Migration energy barriers E m of oxygen ions are mainly affected by the migration distances and peripherally done by the oxygen vacancy cavity size and the defect association. Due to the lager oxygen vacancy cavity size and the smaller defect association in CGOF and CGOCF, the F-dopings have the smaller E m . This is contrary to the speculation of the reported experimental study based on the electronegative comparison of F and O. Our experiment finds that Ca and F co-doping significantly increases the conductivity, 3.9 times of the conductivity of Gd-doped CeO 2 . The study clarifies the nature mechanism of the ionic conductivity in doped CeO 2 , offering atomic-level insights to aid the development of high-performance CeO 2 -based electrolytes.
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JOURNAL OF SOLID STATE CHEMISTRY
·
2025
·
IF 3.5
Yanli Zhang,Jiale Zhao,Simeng Zeng,Zixuan Liu,Bo Wang,Fuhua Lin
In this paper, a novel Cu/F co-doping strategy is proposed to modify the electrochemical performance of Sr 2 Fe 1.5 Mo 0.5 O 6– δ (SFM) cathode for intermediate-temperature solid oxide fuel cells (IT-SOFCs). The pristine SFM, Cu-doped Sr 2 Fe 1.4 Cu 0.1 Mo 0.5 O 6− δ (SFCM) and Cu/F co-doped Sr 2 Fe 1.4 Cu 0.1 Mo 0.5 O 5.9− δ F 0.1 (SFCMF) powders were synthesized by acid-glycine combustion method, and the impacts of Cu/F co-doping on the performance of SFM cathode were investigated systematically. It's found that Cu-doped SFCM has higher oxygen vacancy content and electrical conductivity than the pristine SFM and Cu/F co-doped SFCMF cathodes. While the Coulombic force between B-sites metallic ions and oxygen ions are significantly weaken for SFCMF, enhancing the mobility of lattice oxygen. Due to the combined effects of Cu and F doping, SFCMF cathode exhibits the best electrochemical performance among all investigated samples. At 600 °C, the polarization resistant for SFCMF cathode is 1.79 Ω cm 2 , decreased by 43.71 % in contrast to the parent SFM cathode. These results indicate that Cu/F co-doping is an effective strategy to improve the electrochemical properties of perovskite cathode materials.
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MOLECULES
·
2024
·Vol. 29
·期 23
·5545
·
IF 4.2
Hui Liang,Ruijuan Li,Tongjin Liu,Rumei Li,Yuxiao Zhu,Feng Fang
Peroxymonosulfate (PMS)-based advanced oxidation processes have shown potential for the removal of organic contaminants; however, the preparation of catalysts with high degradation efficiencies and rapid reaction rates remains a challenge. In this study, we have successfully synthesized CoFe bimetallic modified corn cob-derived biochar (CoFe/BC) for the activation of PMS, achieving the rapid and efficient degradation of bisphenol F (BPF). The synthesized CoFe/BC catalyst demonstrated excellent catalytic performance, achieving over 99% removal within 3 min and exhibiting a removal rate of 90.0% after five cycles. This could be attributed to the cyclic transformation of Co and Fe, which sustained rapid PMS activation for BPF degradation, and Co0/Fe0played a significant role in the cyclic transformation. Furthermore, the electron paramagnetic resonance tests confirmed that •SO4−and •OH were the primary reactive oxygen species, while •O2−played a minor role in BPF degradation. This study highlights the high degradation efficiency, rapid reaction rate, excellent magnetic separation properties, and exceptional reusability of CoFe/BC catalysts for BPF removal, providing valuable insights for practical wastewater treatment.
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Nanomaterials
·
2026
·Vol. 16
·期 17
·1119
·
IF 4.8
Jiaqi Yang,Lisen Yuan,Yi Chen,Xiaobin Zhou,Xiaojuan Yan,Gang Zhao,Weiguang Ma
Benzene, toluene, and xylene (BTX) gases pose severe threats to public health on account of their toxic, carcinogenic properties and environmental recalcitrance. In addition, their similar molecular structures and chemical inertness complicate the practical quantification of BTX, severely hindering their high-selectivity detection. In this work, a chemiresistive sensor based on F-doped In2O3nanofibers was constructed. This strategy successfully enhanced the sensor response values toward benzene, toluene, and xylene by approximately 4.3, 4.5, and 4.2 times, respectively. Meanwhile, the limits of detection were reduced from 1, 0.5, and 0.25 ppm to 0.5, 0.25 and 0.05 ppm, respectively. The theoretical lower detection limits for benzene, toluene, and xylene are as low as 9.9 ppb, 5.7 ppb, and 2.5 ppb, respectively. Machine learning methods were further employed for the identification of BTX gases and their binary mixtures. By capturing the distinctive and reproducible patterns of feature vectors from various analytes, the optimal algorithm established decision boundaries and achieved a classification accuracy of 92.1%. Meanwhile, the reasons for the improved gas sensing performance are discussed. Furthermore, a portable wireless gas sensing module based on F-doped In2O3nanofibers was developed, which can be applied for detecting BTX.
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ELECTROCHIMICA ACTA
·
2020
·
IF 6.215
Xiaoqing Liu,Guangshe Li,Dan Zhang,Lingshen Meng,Baoyun Li,Liping Li
Li 3 VO 4 is one of the most promising candidates for high performance lithium-ion batteries due to its high specific capacity and excellent ionic conductivity , while its practical applications are hindered, because of its inferior rate capability. Herein, we adopted an anionic doping strategy to improve electronic conductivity, cycling stability and accelerate electrochemical kinetics. A series of F − doped Li 3 VO 4 samples were synthesized by a modified sol-gel method for the first time. F − doping led to the appearance of oxygen vacancies and reduced band gap, which effectively improve electronic conductivity. Complete structural rearrangement and optimized SEI layers also occurred during cycling, beneficial for stable lifetime. As a consequence, long cycle life (cycling 1100 loops at 500 mA g −1 except for the first 5 loops at 100 mA g −1 ) and optimized rate capability (255 mA h g −1 at 1000 mA g −1 ) were achieved for 5 at% F doping, which are superior to those for undoped samples. This work demonstrates that anion doping is a feasible strategy to accelerate electrons/ions transfer and improve cycling stability of Li 3 VO 4 .
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COMPOSITES SCIENCE AND TECHNOLOGY
·
2021
·
IF 8.528
Xu Xu,Yuting Ouyang,Shaorong Lu,Hong Ruan,Yuqi Li
Triboelectric nanogenerator (TENG) with flexibility, recyclability , and high mechanical performance are highly desirable for self-powered active motion sensors. Herein, maleic anhydride and furan groups were introduced into the polyurethane and SiO 2 , respectively, to obtain furan modified SiO 2 (F–SiO 2 ) and maleic anhydride modified polyurethane (MPU). The dynamic crosslinked F–SiO 2 /MPU composites (FM) possessed the recyclability due to the Diels-Alder reaction. In addition, the mechanical properties of FM were improved due to the improvement of the interface compatibility between F–SiO 2 and MPU. Especially, at 5 wt% content (FM-5), the tensile strength and elongation at break are 7.09 MPa and 845.61%, respectively. Compared with pure MPU, it has increased by 249.26% and 176.30%, respectively. Additionally, at 3 wt% F–SiO 2 content, the short-circuit current ( Isc ), open circuit voltage ( Voc ), transferred charge ( Qsc ) and peak power density of FM-3 increased by 18.60%, 36.04%, 49.24% and 13.00%, respectively. This work offers new insights into the design and preparation of triboelectric nanogenerator for self-powered active motion sensors with flexibility, and recyclability.
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Journal of the American Chemical Society
·
2019
·
IF 14.695
Zhong-Xia Wang,Yi Zhang,Yuan-Yuan Tang,Peng-Fei Li,Ren-Gen Xiong
Antiperovskites have developed to be one kind of important functional material over the past few decades, showing abundant physical properties such as negative thermal expansion and superconductivity, etc. However, antiperovskite ferroelectrics have scarcely been discovered in inorganic ceramics. In this article, we report a new organic–inorganic hybrid antiperovskite ferroelectric [(CH3)2(F-CH2CH2)NH]3(CdCl3)(CdCl4) based on the strategy of molecular design. The replacement of one methyl in [(CH3)3NH]CdCl3 with ethyl produces the lower symmetric [(CH3)2(CH2CH3)NH]CdCl3 with nonpolar perovskite structure, while the polar hexagonal antiperovskite structure with the formula of X3BA (where X = [(CH3)2(F-CH2CH2)NH]+, B = [CdCl3]−, and A = [CdCl4]2–) was received after further fluoridation of the ethyl group. Therefore, fluoridation successfully achieves the structural transformation from perovskite to antiperovskite, as well as the significant changes in physical properties from nonferroelectric to ferroelectric. The antiperovskite [(CH3)2(F-CH2CH2)NH]3(CdCl3)(CdCl4) exhibits typical ferroelectric phase transition above room temperature (Tc = 333 K) including thermal anomalies, dielectric transitions, and second harmonic generation (SHG) responses. Moreover, lower coercive fields and easy polarization switching are observed by the measurements of hysteresis loops and ferroelectric domains. The saturated polarization (Ps) of 4.0 μC/cm2 is almost 10 times as large as those recently discovered antiperovskite molecular ferroelectrics. This finding provides a novel strategy to design and explore more antiperovskite organic–inorganic hybrid ferroelectric materials.
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