Foods
·
2025
·Vol. 14
·期 14
·2421
·
IF 5.1
Mengqiong Yang,Guangming Mei,Daoxiang Huang,Xiaojun Zhang,Pengfei He,Si Chen
A sensitive method was developed for detecting diazepam residues in aquatic products using magnetic dispersive solid-phase extraction (MDSPE) coupled with ultra-performance liquid chromatography–tandem mass spectrometry (UPLC-MS/MS). Samples extracted with 1% ammonia–acetonitrile were purified using synthesized Fe3O4@SiO2-PSA nanoparticles via MDSPE before UPLC-MS/MS analysis. Separation was performed on a C18column with gradient elution using 0.1% formic acid–2 mM ammonium acetate/methanol. Detection employed positive electrospray ionization (ESI+) in multiple reaction monitoring (MRM) mode. Characterization confirmed Fe3O4@SiO2-PSA’s mesoporous structure with excellent adsorption capacity and magnetic properties. The method showed good linearity (0.1–10 μg/L,r> 0.99) with an LOD and LOQ of 0.20 μg/kg and 0.50 μg/kg, respectively. Recoveries at 0.5–15.0 µg/kg spiking levels were 74.9–109% (RSDs 1.24–11.6%). This approach provides rapid, accurate, and high-precision analysis of diazepam in aquatic products, meeting regulatory requirements.
研究领域:
分析化学
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食品安全
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材料科学
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产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2025
·Vol. 15
·期 11
·8111-8120
·
IF 4.6
Hao Zhang,Weihao Ma,Chunyu Qiang,Jiayuan Nie,Ling Ma,Yawei Zhang,Ke Wang
In our research, an emerging magnetic covalent organic framework (Fe3O4@SiO2–BD–DADB-COF) was formulated through Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), etc. Several parameters affecting the extraction process were refined. Accordingly, a novel method of determining 15 macrolides (MALs) in honey and water was established through the Fe3O4@SiO2–BD–DADB-COF as a magnetic solid-phase extraction (MSPE) adsorbent and ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). In consequence, the standard curves for the 15 MALs exhibited an exceptional linearity from 0.1 to 200 μg L−1, and the correlation coefficients (R2) varied from 0.9990 to 0.9999. The recoveries fell between 70.01% and 115.56%, with the relative standard deviations (RSDs) being below 9.93% (n = 5). The detection limits reached 0.001–0.075 μg L−1 with the quantification limits being 0.004–0.228 μg L−1. Ultimately, the method was excellently applied to the analysis of MALs in honey and water.
研究领域:
分析化学
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环境科学
·
食品科学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
·
2021
·
IF 4.291
Ao Li,Linbei Xie,Sijie Zhou,Min Zhang,Yi Ding,Ping Wang
In this study, the magnetic core-shell nanomaterial Fe 3 O 4 /SiO 2 /N-TiO 2 /Ag/AgCl (FSNT/Ag/AgCl) that efficiently degraded methyl orange (MO) was produced. The dosages of tetrabutyl titanate (TBOT), urea and AgNO 3 were optimized by response surface methodology (RSM). Scanning electron microscope (SEM), transmission electron microscope (TEM), X-ray photoelectron spectroscopy analysis (XPS), energy dispersive spectrometer (EDS), X-ray diffractometer (XRD), fourier transform infrared spectrometer (FT-IR), and UV–vis diffuse reflectance spectrum (UV–vis DRS) were used to characterize the nanomaterial. The particle size of FSNT/Ag/AgCl was 91.98 nm, and it presented a core-shell structure with Fe 3 O 4 as the core, SiO 2 and N-TiO 2 wrapped in Fe 3 O 4 , and Ag/AgCl deposited on the outermost layer. Performance and mechanism research experiments showed that under the optimized conditions of 1 g/L FSNT/Ag/AgCl, pH = 9, temperature of 35℃ and initial MO concentration of 10 mg/L, about 90 % of MO was degraded in 20 min. The mineralization rate was 35.2 % within 120 min. Holes (h + ) and superoxide anions (·O 2 − ) were the main active substances in the whole photocatalytic degradation. FSNT/Ag/AgCl could be recovered by magnet. After 5 repeated experiments, the degradation rate of MO within 100 min still reached 88.5 %. This work provides a recyclable core-shell nanomaterial for faster degradation of dye wastewater.
研究领域:
材料科学
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环境科学
·
纳米技术
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
REACTIVE & FUNCTIONAL POLYMERS
·
2020
·
IF 3.333
Jiahong Wang,Min Mao,Saleem Atif,Yao Chen
The presence of widely used chelating agents such as ethylenediaminetetraacetic acid (EDTA) in aqueous solution increases the difficulty of heavy metal removal by the formation of heavy metal chelates. In this study, diethylenetriaminepentaacetic acid (DTPA)-chitosan functionalized magnetic silica (Fe 3 O 4 @SiO 2 /Cs-DTPA) was developed for the removal of Cr(III) and Cr(III)-EDTA. The obtained results from characterization confirmed that Fe 3 O 4 @SiO 2 /Cs-DTPA with the core-shell structure and superparamagnetic properties was synthesized. The maximum theoretical adsorption capacity of Cr(III) and Cr(III)-EDTA chelates on the adsorbents were 39.27 and 22.24 mg/g at 25 °C and pH 4.0, respectively. Adsorption equilibrium of Cr(III) and Cr(III)-EDTA on Fe 3 O 4 @SiO 2 /Cs-DTPA was achieved within 15 min, and the adsorption data fit the pseudo second-order model. The co-existing complex agents (EDTA) and cations (Na + , Ca 2+ , and Mg 2+ ) in the aqueous solution reduced Cr(III) adsorption by the competition with Cr(III) and Cr(III)-EDTA chelate for active groups of the adsorbent. The affinity of the Fe 3 O 4 @SiO 2 /Cs-DTPA for Cr(III) and Cr(III)-EDTA was excellent even at high salt and organic chelates concentration. The Cr(III) adsorption was attributed to surface complexation between Cr(III) and DTPA moieties of the adsorbent, while Cr(III)-EDTA as a whole was adsorbed on the adsorbent by the complexation and electrostatic interaction . Cr(III) saturated Fe 3 O 4 @SiO 2 /Cs-DTPA can be readily regenerated in acid solution and Cr(III) or Cr(III)-EDTA adsorption of regenerated adsorbent exhibits no obvious reduce.
研究领域:
环境科学
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材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
Materials
·
2013
·Vol. 6
·期 4
·1255-1269
·
IF 2.247
Ning Gan,Xiaowen Du,Yuting Cao,Futao Hu,Tianhua Li,Qianli Jiang
An ultrasensitive portable electrochemical immunosensor for human immunodeficiency virus p24 (HIV p24) antigen detection has been developed, whereby the detection sensitivity was 1000 times higher than that of the ELISA method. Firstly, a novel HRP enzyme–antibody copolymer (EV-p24 Ab2) was synthesized through an EnVision regent (EV, a dextrin amine skeleton anchoring more than 100 molecules of HRP and 15 molecules of anti IgG), then incubated in the secondary antibody of p24. Secondly, the copolymer was immobilized on the gold nanocolloids (AuNPs) to fabricate a novel signal tag (AuNPs/EV-p24 Ab2). Subsequently, a sandwich-type immunoreaction would take place between the capture probe (silicon dioxide-coated magnetic Fe3O4nanoparticles (MNPs) labeled with the primary p24 antibody (MNPs-p24 Ab1)), p24 (different concentrations) and the signal tag [AuNPs/EV-p24 Ab2)] to form the immunocomplex. Finally, the immunocomplex was absorbed on the surface of screen printed carbon electrode (SPCE) by a magnet and immersed in the o-hydroxyl phenol (HQ) and H2O2. The large amounts of HRP on the signal tag can catalyze the oxidation of HQ by H2O2, which can induce an amplified reductive current. Moreover, the capture probe could improve the accumulation ability of p24 and facilitate its separation from the substrate through the magnet. Under optimal conditions, the proposed immunoassay exhibited good sensitivity to p24 within a certain concentration range from 0.001 to 10.00 ng/mL, with a detection limit of 0.5 pg/mL (S/N = 3). The proposed method can be used for real-time and early detection of HIV-infected people.
研究领域:
生物医学工程
·
病毒学
·
分析化学
✓ 已验证
DOI
高影响因子
ACS Applied Nano Materials
·
2024
·
IF 5.3
Jia Deng,Shaoge Fu,Yifan Zhong,Ming Jiang,Tao Chen,Haili Zhao
Photonic crystal (PC) hydrogels with unique micro/nanostructures have excellent prospects in many fields, such as sensing, displays, anticounterfeiting, information encryption, and adaptive camouflage. Herein, magnetic core–shell Fe3O4/SiO2 nanoparticles with a controlled size were synthesized, followed by PC hydrogels of arbitrary structures that were fabricated via the magnetically inducing self-assembly of magnetic nanoparticles in the poly(ethylene glycol) diacrylate (PEGDA) pregel solution and a subsequent digital micromirror device (DMD)-based UV polymerization process. By controlling the size of nanoparticles and magnetic field intensity, various PC hydrogel patterns with tunable structural colors were fabricated. Combining magnetic field control with DMD-based light modulation, high-throughput preparation of structural color PC hydrogels was achieved. Furthermore, the Fe3O4/SiO2 nanoparticles were assembled into poly(2-hydroxyethyl methacrylate) (PHEMA) with solvent responsiveness. Interestingly, the obtained PC hydrogels could swell in ethanol, resulting in a change in the structural color. Meaningfully, a dual-component PC hydrogel consisting of a PEGDA pattern and a PHEMA background was fabricated, and the invisible pattern in the initial state could be displayed and hidden through cyclic exposure to ethanol and ethylene glycol. The presented strategy for constructing the PC hydrogels from Fe3O4/SiO2 nanoparticles could provide valuable insights for the development of intelligent structural color materials, which exhibit significant potential in applications such as information storage, visual sensing, and anticounterfeiting.
研究领域:
材料科学
·
纳米技术
·
光学
·
化学
·
防伪技术
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2022
·Vol. 47
·期 3
·1216-1225
·
IF 3.925
Anqi Niu,Hang Xu,Qinlin Yuan,Fengmin Wu,Xuefeng Wei
Lewis acidic ionic liquid-loaded Fe3O4@SiO2 magnetic catalytic microspheres were prepared. When coupled with persulfate, the microspheres catalytically oxidized and removed dibenzothiophene (DBT) from octane. The microspheres used for catalytic desulfurization were characterized and analyzed by SEM, TEM, FT-IR, VSM, and TG-DTA. The results indicated that the prepared catalytic desulfurization microspheres had a uniform particle size distribution, an overall diameter of 200 nm, and a core diameter of Fe3O4 of about 180 nm. The saturation magnetization of the catalytic desulfurization microspheres was 39.8 emug−1, which allowed them to be rapidly magnetically separated. The optimal experimental conditions were 1.5 g catalyst, 1.2 g PMS (20%) oxidant, 30 °C, an initial sulfur content of 500 ppm, 6.0 g octane, and 3.0 g acetonitrile. Under these conditions, the desulfurization rate reached 98.5% after 25 min, which decreased by about 10% after five recycles. GC-MS analysis indicated the oxidation product was dibenzothiophene sulfone (DBTO2). In the desulfurization mechanism, DBT was first extracted by acetonitrile. Then, in the acetonitrile phase, Co2+ catalyzed hydrogen persulfate to form active oxygen atoms that oxidized DBT and eventually formed DBTO2.
研究领域:
化学工程
·
环境科学
·
材料科学
·
分析化学
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2015
·
IF 4.321
Jie-Ping Fan,Xiao-Kang Xu,Rui Xu,Xue-Hong Zhang,Jian-Hang Zhu
In this work, the superparamagnetic Fe 3 O 4 particles prepared by the coprecipitation method were coated successively by SiO 2 , vinyl end groups and molecularly imprinted polymer (MIP) shells to afford a pomegranate-like core/shell superparamagnetic particle (Fe 3 O 4 @SiO 2 @MIP), and the MIP shell preparation conditions were optimized by multi-objective response surface methodology. In order to simultaneously enrich and separate the four taxoids (10-DAB, baccatin III, cephalomannine and paclitaxel), cephalomannine was selected as the template because of its similar chemical structure to other three taxoids and relative inexpensiveness. Especially, to avoid template leaking which may influence the accuracy of identification and quantitation of the analytes, we selected paclitaxel as the target molecular during the investigation of the adsorption property of Fe 3 O 4 @SiO 2 @MIP particles. This strategy was similar to the dummy molecular imprinting technique in which the dummy molecularly imprinted polymer was prepared by using a dummy template, structural analog of the target analyte. The as-prepared Fe 3 O 4 @SiO 2 @MIP particles were characterized by transmission electron microscopy (TEM), vibrating sample magnetometer (VSM), and Fourier transform infrared spectroscopy (FTIR). The adsorption kinetics, isotherms and reusability were also investigated. Finally, the Fe 3 O 4 @SiO 2 @MIP particles were successfully applied to simultaneously enrich and separate these four taxoids in the extract of Taxus × media ( T. × media ).
研究领域:
分析化学
·
材料科学
·
药学
✓ 已验证
产品关联
DOI
高影响因子
BIOINORGANIC CHEMISTRY AND APPLICATIONS
·
2022
·
IF 4.724
Yuqin Yang,Junjie Miao,Zhendong Yin,Weili Hao,Hongmei Shi,Ling Ma,Tiesheng Shi
Efficient extractions of trace antibiotic residues in the environment are a key factor for accurate quantification of the residues. A new nanoporous material, namely, magnetically covalent organic polymer (MCOP, Fe3O4@SiO2-NH2-COP) was synthesized in this work and was used for magnetic solid-phase extraction (MSPE). The combination of MSPE with high-performance liquid chromatography separation together with ultraviolet detection (HPLC-UV) was established as an effective method for the determination of four sulfonamide (SA) residues in surface water surrounding a cattle farm. The synthesized magnetic material was characterized by SEM, TEM, FT-IR, magnetic properties measurement system (MPMS), and nitrogen gas porosimetry. The material possessed many attractive features, such as a unique microporous structure, a larger specific surface area (137.93 m2·g−1) than bare Fe3O4 (24.84 m2·g−1), high saturation magnetization (50.5 emu·g−1), open adsorption sites, and high stability. The influencing parameters, including pH, the used amount of MCOPs, the type of eluent, adsorption solution, and desorption time, were optimized. Under the optimized conditions, the method conferred good linearity ranges (R2 ≥ 0.9990), low detection limits (S/N = 3, LOD, 0.10–0.25 μg·L−1), and satisfactory recoveries (79.7% to 92.2%). The enrichment factor (EF) for the four SAs was 34.13–38.86. The relative standard deviations of intraday (n = 5) and of interday (n = 3) were less than 4.8% and 8.9%, respectively. The equilibria between extraction and desorption for SAs could be reached within 150 s. The proposed method was sensitive and convenient for detecting SA residues in complex environmental matrices, and the successful application of the new MCOPs as an adsorbent was demonstrated.
研究领域:
环境科学
·
分析化学
·
材料科学
·
水质
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2016
·
IF 5.886
Wenfen Zhang,Yanhao Zhang,Qiong Jiang,Wenjie Zhao,Ajuan Yu,Hong Chang,Ximei Lu,Fuwei Xie,Baoxian Ye,Shusheng Zhang
To satisfy the requirement of simultaneous extraction and characterization of diverse kinds of multitarget analytes, the preparation, characterization, and application of a novel tetraazacalix[2]arene[2]triazine (TCT) coated magnetic nanoparticle (TCT MNP) adsorbent are presented in this paper. TCT assembles two benzene rings and two triazines with nitrogen cross-bridging links, which exhibits a unique structural framework and versatile recognition features based on the multiple recognition sites. These include π electron stacking, charge transfer, hydrogen bonding, and ion-exchange. TCT MNPs acted as a dispersive SPE adsorbent showing strong interaction with and adsorption of polycyclic aromatic hydrocarbons (PAHs), nitroaromatics, and heavy metal ions. The dispersive magnetic nanoparticle solid phase extraction (d-MNSPE) strategy with the simultaneous extraction and stepwise elution (SESE) procedure was designed and optimized for the five PAHs (phenanthrene, anthracene, pyrene, chrysene, and benzo(a)pyrene), six nitroaromatics (4-nitrotoluene, 2,4-dinitrotoluene, 2,4,6-trinitrotoluene, 4-nitrophenol, 2,4-dinitrophenol, and 2,4,6-trinitrophenol), and four metal ions (Cu, Zn, Mn, Cd) in aqueous samples. Due to the high stability, desirable durability, larger saturation magnetization, reuse and distinct enrichment capacity of TCT MNPs, the d-MNSPE method with the SESE strategy provided high recovery (>90%) and good precision (relative standard deviations, RSD < 10%). Coupled with the commonly used HPLC-fluorescence detection, HPLC-UV detection, and atomic absorption spectrometry, these trace probes in tap water, river water, and lake water were determined with very low detection limits, in the range of 0.09–0.15 pg mL–1 for PAHs, 6–11 pg mL–1 for nitroaromatics, and 17–53 pg mL–1 for metal ions after being enriched by the d-MNSPE. The determination of trace PAHs in urine samples from smokers and nonsmokers was successfully carried out with this method, which implied that the versatile TCT MNPs and the robust method together represent a significant potential application in the analysis of body fluids and disease markers. Such methods for accurate quantification of trace components in water are very valuable as they fulfill an unmet need in environmental and medicinal chemistry.
研究领域:
分析化学
·
环境科学
·
材料科学
·
药物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMOSPHERE
·
2023
·
IF 8.8
Zhenzhen Liu,Huiyu Zhao,Jiao Wang,Zhiwei Wang,Shanshan Di,Hao Xu,Qiang Wang,Xinquan Wang,Peipei Qi
A biosafe magnetic Fe 3 O 4 @SiO 2 @Salg (GMS) was successfully developed via a simple and economic method. Fe 3 O 4 @SiO 2 particles were selected as the magnetic core, and they directly interacted with sodium alginate, thus mitigating the use of cross-linking agents. The microstructure, properties, and formation mechanism of GMS were examined using FE-SEM, TEM, VSM, TGA , zeta potential , and FT-IR. The as-developed GMS was used as a desirable adsorbent to remove organophosphorus pesticides (OPPs) from water bodies, and the influence of different factors on the removal efficiencies of OPPs was investigated. Optimal preparation conditions were determined, and the excellent removal efficiencies of the 18 OPPs were achieved in this study (80.5%–100% for tap, river, and seawater). After the GMS was recycled eight times, the removal efficiencies of 18 OPPs were maintained at >80%. Adsorption kinetics and isotherm models showed that the adsorption process was accurately fitted with the Langmuir isotherm and pseudo-second-order models. The values of ΔG , ΔH , and ΔS were negative, indicating that the OPPs were adsorbed on the GMS spontaneously via an exothermal reaction, and chemisorption was the dominant adsorption mechanism. Overall, the as-developed GMS was biosafe as revealed by cytotoxicity experiments. GMS had good environmental security, stability, and reusability, and it exhibited excellent potential for removing OPPs from aqueous solutions without causing secondary pollution.
研究领域:
环境科学
·
材料科学
·
化学
·
纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHINESE JOURNAL OF CHEMICAL ENGINEERING
·
2021
·
IF 3.171
Dongze Ma,Ye Tian,Tiefei He,Xiaobiao Zhu
Novel magnetic nanoparticles (MNPs), Fe 3 O 4 @SiO 2 and Fe 3 O 4 @SiO 2 @PEG-(COOH) 2 , were prepared by loading different amounts of SiO 2 or/and PEG-(COOH) 2 onto Fe 3 O 4 nanoparticles, and their feasibility to be used as forward osmosis (FO) draw solutes was investigated. The characterization of the materials showed that, compared to normal Fe 3 O 4 nanoparticles, the modified MNPs exhibited enhanced dispersity and high osmotic pressure in aqueous solution. The FO experiment indicated that the synthesized draw solutes could obtain a water flux as high as 10 L∙m −2 ·h −1 with an aquaporin FO membrane. The optimal concentration of the added tetraethyl orthosilicate was 30% during the synthesis. The novel MNPs could be easily recovered from draw solutions by magnetic field, and the recovery rate of Fe 3 O 4 @SiO 2 and Fe 3 O 4 @SiO 2 @PEG-(COOH) 2 was 83.95% and 63.37%, respectively. Moreover, after 5 recycles of reuse, the water flux of Fe 3 O 4 @SiO 2 and Fe 3 O 4 @SiO 2 @PEG-(COOH) 2 as draw solutes still remained 64.36% and 85.26%, respectively. The experimental results demonstrated that the synthesized core–shell magnetic nanoparticles are promising draw solutes, and the Fe 3 O 4 @SiO 2 @PEG-(COOH) 2 was more suitable to be used as draw solute in FO process.
研究领域:
材料科学
·
环境工程
·
化学工程
·
纳米技术
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）