International Journal of Pharmaceutics-X
·
2026
·
IF 7.9
Xiaofang Wang,Jun Chen,Tingyi Guo,Huisheng Yao,Nan Li,Zhenggang Li,Jia Li
Diabetic wounds are characterized by excessive oxidative stress, persistent inflammation, and impaired tissue regeneration, which collectively hinder normal wound healing. Here, we developed a near-infrared (NIR)-responsive sodium alginate hydrogel incorporating nano‑iron sulfide (nFeS) through mild gelation mediated by calcium carbonate and glucono-δ-lactone. The resulting SA-nFeS hydrogel exhibited a porous structure, favorable rheological properties, hydrogen peroxide-responsive degradation, radical-scavenging activity, and good cytocompatibility. NIR irradiation accelerated the release of Fe from the hydrogel, increasing the cumulative release from approximately 35.5% to 75.4% over 48 h. In cells exposed to oxidative stress, the NIR-treated SA-nFeS hydrogel markedly reduced intracellular reactive oxygen species and promoted Nrf2 nuclear translocation, accompanied by decreased Keap1 expression and increased expression of the downstream antioxidant proteins HO-1, SOD1, SOD2, and GPX4. Furthermore, the hydrogel suppressed pro-inflammatory macrophage markers and cytokines while increasing the expression of CD206, Arg-1, and IL-10, indicating a shift toward a pro-healing macrophage phenotype. In a streptozotocin-induced diabetic full-thickness wound model, SA-nFeS combined with NIR irradiation achieved approximately 93% wound-area reduction by Day 14 and promoted re-epithelialization, granulation tissue formation, and collagen deposition. No obvious histopathological abnormalities were observed in the major organs. Collectively, these findings demonstrate that the NIR-responsive SA-nFeS hydrogel promotes diabetic wound repair by activating endogenous antioxidant defense and modulating the inflammatory microenvironment, providing a promising therapeutic platform for chronic wound management. Download: Download high-res image (253KB) Download: Download full-size image
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高影响因子
JOURNAL OF POWER SOURCES
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2024
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IF 8.1
Dan Yuan,Shungang Wan,Yong Xiao,Lei Sun
This study involves the construction of an “inside-out” electronic network channel with in-situ formation of biogenic FeS (bio-FeS) nanoparticles in cells of Shewanella oneidensis MR-1 ( S . oneidensis MR-1) and a coating of conductive polypyrrole (PPy) on the outer surface of entire cells. The microbial fuel cell driven by bio-FeS and PPy co-modified S . oneidensis MR-1 (FeS/PPy@MR-1) has a maximum power density 3.6 times higher than that of the native strain. Electrochemical analysis demonstrates that the modifications of bio-FeS and PPy markedly enhance the direct electron transfer and c -type cytochrome-bound flavin-mediated single-electron reaction pathways and expand the electron output flux. The electron-donating ability of FeS/PPy@MR-1 is 7 times greater than that of the native strain. Bio-FeS and PPy can mediate novel intra/extracellular transmembrane electron transport pathways independent of the traditional respiratory chain, bridge spatially discrete redox environments, and optimize electron transfer pathways to intracellular to extracellular transfer electrons rapidly and maximally. These findings provide insights into conductive nanomaterial-mediated intra/extracellular transmembrane electron transfer, which is critical for the environment and bioenergy fields.
研究领域:
环境科学
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生物能源
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微生物学
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COMPOSITES PART B-ENGINEERING
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2022
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IF 11.322
Jujun Yuan,Meiqi Mu,Xijun Xu,Yunfei Gan,Haishan He,Xianke Zhang,Xiaokang Li,Fanguang Kuang,Haixia Li,Jun Liu
The three-dimensional (3D) FeS@N doped Carbon (NC) nanosheets are successfully synthesized using a simple sol-gel method followed by a solid sulfidation process. As SIBs anode, the 3D FeS@NC nanosheets exhibit a maintainable capacity (254 mAh g −1 at 1.5 A g −1 upon 1100 cycles) and outstanding rate behaviour. As PIBs anode, the 3D FeS@NC nanosheets also exhibit a maintainable capacity (120 mAh g −1 at 1 A g −1 upon 1100 cycles) and outstanding rate behaviour. The excellent electrochemical performance can be attributed to the distinctive 3D porous FeS@NC nanosheets, which can inhibit the aggregation and pulverization of FeS, enhance electronic/ionic conductivity, firmly immobilize the dissolved polysulfides , and provide a larger contact area between active materials and electrolytes. Moreover, the N-doped carbon framework can also provide substantial active sites for Na + (K + ) storage. Our synthesizing strategy can be potentially utilized for fabricating other 3D metal sulfide@C composites for SIB (PIB) anodes.
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DALTON TRANSACTIONS
·
2021
·Vol. 50
·期 37
·13052-13058
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IF 4.39
Hui Zheng,Changhao Ding,Han-Shu Xu,Lulu Tang,Huimin Liu,Lianwei Wei,Kaibin Tang
Several FeS-derived intercalated compounds (C2H8N2)xFeS and Ax(C2H8N2)yFeS (A = Li, Na) were successfully synthesized via a novel ammonothermal method. The powder X-ray diffraction (XRD) measurements reveal that the FeS intercalated samples have the same tetragonal crystal structure as the parent FeS. After intercalation, these three as-synthesized samples do not show superconductor behavior, which is confirmed by the magnetization and the electrical resistivity measurements. (C2H8N2)xFeS exhibits paramagnetic semiconductor behavior, while the newly synthesized Ax(C2H8N2)yFeS (A = Li, Na) shows antiferromagnetic semiconductor behavior. The absence of superconductivity in these FeS-derived compounds should be closely related to the iron vacancies in the FeS layer.
研究领域:
材料科学
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固体化学
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凝聚态物理
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Journal of Materials Chemistry A
·
2018
·Vol. 6
·期 16
·7155-7161
·
IF 9.931
Mingbao Huang,Anding Xu,Huanhuan Duan,Songping Wu
To meet heavy-duty applications for LIBs, development of superior electrode materials with high-efficiency lithium-storage capability has become very crucial and urgent. Herein, a simple one-pot method has been developed for the synthesis of a reduced graphene oxide-wrapped FeS nanoflake (FeS@rGO) composite using oleylamine as a solvent, reductant, and surfactant. The as-prepared FeS@rGO composite as an anode material for LIBs showed excellent cycling ability and rate performance, i.e., reversible capacities of 887 mA h g−1 at the current density of 200 mA g−1 after 150 cycles, 662 mA h g−1 at 1.0 A g−1 after 200 cycles, and 325 mA h g−1 at 5.0 A g−1 even after 1000 cycles. These enhanced electrochemical performances can be attributed to the unique cladding structure, in which rGO can act as a protective coating to accommodate volume changes of FeS upon Li-cycling and offer a fast electron transfer channel. A two-dimensional sheet structure also facilitates Li+ ion diffusion in active electrode materials. More importantly, the enhanced extrinsic pseudocapacitance can promote the charge transfer rate and afford significant Li-storage capacity, thereby promoting the rate capability of a material at large current densities. Therefore, as a promising anode with high power density and long lifespan, this composite has shown its distinct potential and advantage for heavy-duty LIBs.
研究领域:
材料科学
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电化学
·
纳米能源材料
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储能技术
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先进电池
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CHEMOSPHERE
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2023
·
IF 8.8
Cui Shang,Youzheng Chai,Liang Peng,Jihai Shao,Hongli Huang,Anwei Chen
In-suit immobilization is one of the major strategies to remediate heavy metals contaminated soil with the effectiveness largely depends on the characteristics of the added chemical reagents/materials. In this study, chitosan stabilized FeS composite (CS–FeS) was prepared to evaluate the performance of remediating the high and toxic hexavalent chromium contaminated soil from the effectiveness and microbial response aspects. The characterization analysis confirmed the successful preparation of composite, and the introduction of chitosan successfully stabilized FeS to protect it from rapid oxidation as compared to bare FeS particles. With the addition dosage at 0.1%, about 85.6% and 81.3% of Cr(VI) was reduced in 3 d based on toxicity characteristic leaching procedure (TCLP) and CaCl 2 extraction, and the reduction efficiency increased to 96.6% and 94.8% in 7 d, respectively. The Cr(VI) was non-detected in the TCLP leachates with increase the CS-FeS composites to 0.5%. The percentages of HOAc-extractable Cr decreased from 25.17% to 6.12% accompanied with the increase in the residual Cr from 4.26% to 13.77% and improvement of soil enzyme activity under CS-FeS composites addition. Cr(VI) contamination reduced the diversity of microbial community in soil. Three dominate prokaryotic microorganisms , namely Proteobacteria , Actinobacteria and Firmicutes , were observed in Cr-contaminated soil. The addition of CS-FeS composites increased the microbial diversity especially for that in relative lower abundance. The relative abundance of Proteobacteria and Firmicute related to Cr-tolerance and reduction increased in CS-FeS composites added soils. Taking together, these results demonstrated the potential and promising of using the CS-FeS composites for Cr(VI) polluted soil remediation .
研究领域:
环境科学
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微生物学
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土壤化学
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高影响因子
Journal of Water Process Engineering
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2022
·
IF 7.34
Mengyao Han,Luxin Liang,Yazi Wang,Yuwei Deng,Qiuyue Zhang,Yuxuan Ye,Dandan Wang,Qiang Li,Fei Pan,Dongsheng Xia
The effective control of antibiotic pollution in water has become an important issue in the field of environmental protection. In this study, the composite of iron sulfide and melamine sponge (FeS@MS) was successfully synthesized by in-situ synthesis method and applied to the oxidative removal of tetracycline (TC) in the presence of peroxymonosulfate (PMS). Under optimal conditions ([FeS@MS] = 0.1 g/L and [PMS] = 0.2 mM), 95.7% of TC was degraded in 5 min. The presence of NO 3 − , SO 4 2− , and Cl − slightly inhibited TC removal, whereas HPO 4 − had a certain promotion effect in activating PMS to degrade TC. The primary reactive oxygen species (ROS), including SO 4 − , OH , 1 O 2 , and O 2 − were identified through electron paramagnetic resonance (EPR) spectroscopy and radical quenching experiments. In addition, Fe 3+ in solution could react with FeS to produce Fe 2+ , which continuously activates PMS to generate radicals for TC degradation. The presence of MS reduced the agglomeration of FeS and played a protective role in the slow release of Fe 2+ . The degradation performance was further validated in real water matrices. This study provided new insight into fabricating functional material for the remediation of antibiotic wastewater.
研究领域:
环境科学
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材料科学
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ELECTROCHIMICA ACTA
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2019
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IF 5.383
Ruizhi Zhang,Zhaoqiang Zhu,Jiahao Lin,Kefu Zhang,Nan Li,Chongjun Zhao
Non-noble-metal based catalysts for overall water splitting have attracted widespread attention. Herein, we report a Fe(II) hydrolysis reaction assisted in-situ etching and growth method for the design of Fe 2 O 3 nanoparticles-anchored ultrathin Ni(OH) 2 nanosheets composites on nickel foam (Fe 2 O 3 /Ni(OH) 2 /NF), followed by solvothermal sulfidation conversion into FeS/NiS/NF electrode. As-prepared FeS/NiS/NF electrode possesses low overpotentials of 203 mV and 144 mV to achieve a current density of 10 mA cm −2 in 1.0 M KOH for OER and HER, respectively. FeS/NiS/NF directly serves as both anode and cathode to assemble a two-electrode water electrolyzer, which only requires a voltage of 1.618 V to afford water-splitting current density of 10 mA cm −2 in 1.0 M KOH. Additionally, this water splitting device can also be driven by using photovoltaic solar panels. This work provides a new strategy to tailor the components and structure of the catalyst and thus to improve electrocatalytic performance.
研究领域:
材料科学
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电化学
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JOURNAL OF ALLOYS AND COMPOUNDS
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2022
·
IF 6.371
Wan Hui Guo,Qing Zhang,Hong Chuan Fu,Yu Xian Yang,Xiao Hui Chen,Hong Qun Luo,Nian Bing Li
The efficiency of water electrolysis is greatly hindered by complex electron-proton transfer process of oxygen evolution reaction (OER). Exploiting cost-efficient OER electrocatalytic materials to improve the performance of overall water splitting is necessary. Partial chemical etching of iron foam (IF) with glacial acetic acid, using IF as the metal source and substrate, to form vertically aligned FeS/Fe 2 O 3 heterogeneous nanosheets on the IF (FeS/Fe 2 O 3 /IF) can obtain a hierarchical electrode to meet the above requirements. The nanosheets with heterogeneous interfaces in situ grown on IF can adjust electronic structure and expose more active sites, resulting in great improvement of catalytic activity and stability. FeS/Fe 2 O 3 /IF requires a small overpotential of 266.5 mV to attain 10 mA cm −2 and its Tafel slope is 51.17 mV dec −1 . It is worth noting that FeS/Fe 2 O 3 /IF can work continuously for 50 h at high current density, which proves the strong stability during the OER process. The FeS/Fe 2 O 3 /IF has high electrocatalytic activity and stability, and can be used as a good candidate material for electrocatalytic OER in industrial manufacture.
研究领域:
材料科学
·
电化学
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2026
·
IF 2.8
Yuning Yang,Qiao Yan,Yiming Zhou
Chromium (Cr) ions, as a critical pollutant in industrial wastewater, posed a persistent challenge for research aiming to realize their efficient removal alongside detoxification. Here, we presented a novel cellulose-based nanoadsorbent, PDA@CNCs/FeS, obtained via dopamine (DA) self-polymerization onto cellulose nanocrystals (CNCs) and subsequent FeS nanoparticle immobilization. Experimental results demonstrated that the adsorbent achieved a high removal capacity of 837.9 mg/g for Cr(VI) and exhibited efficient removal under mildly acidic conditions (pH 5.0), which outperformed the majority of cellulose-based adsorbents. The adsorption followed the Langmuir isotherm model and fitted well with the Pseudo-second-order kinetic. FTIR and XPS analyses confirmed the adsorption mechanism, which revealed that electrostatic attraction was involved in Cr(VI) removal, while the synergistic effect between reductive PDA and FeS on the nanoadsorbents facilitated the detoxification of toxic Cr(VI) to less harmful Cr(III). Nearly 70% of the adsorbed Cr(VI) was reduced to Cr(III), with a final ratio of 31.4%:68.6% for Cr(VI):Cr(III). Furthermore, PDA@CNCs/FeS also demonstrated excellent reusability, with over 80% of its Cr(VI) removal efficiency remaining after four adsorption–desorption cycles; these findings implied that PDA@CNCs/FeS held great promise as an adsorbent for Cr(VI) remediation in water treatment.
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APPLIED CATALYSIS B-ENVIRONMENTAL
·
2026
·
IF 19.7
Die Yuan,Kai Li,Xuebin Lu,Chaoqin Zhao,Guijian Zhang,Ping Ning,Dongdong Zhang,Xin Sun,Shuangyou Bao,Chi Wang
A dual-channel electron-donation pathway enables reductant-free Fe 2+ /Co 2+ regeneration. • Pollutants and S 2- synergistically drive reversible M(III)/M(II) redox cycling. • Co 9 S 8 /FeS/PMS achieves rapid and complete levofloxacin degradation within 10 min. A magnetic Co 9 S 8 /FeS composite derived from cobalt slag was developed for reductant-free PMS activation through a novel dual-channel electron-donation pathway involving S 2- species and levofloxacin (LEV). The catalytic performance and mechanism were investigated through degradation kinetics, reactive-species identification, X-ray absorption fine spectroscopy (XAFS), X-ray photoelectron spectroscopy (XPS) analyses, density functional theory (DFT) and life cycle assessment. The Co 9 S 8 /FeS/PMS system completely degraded LEV within 10 min (k = 0.4498 min −1 ), maintained efficient removal over pH 3.0–11.0 and after five cycles (>95%), with 1 O 2 as the dominant reactive species. DFT calculations, together with XAFS/XPS analyses, revealed that S 2− and LEV serve as dual electron donors to facilitate Fe 3+ /Co 3+ reduction, achieving nearly complete Fe/Co redox cycling and sustained PMS activation. Compared with conventional single-electron-donor Fenton-like systems, this strategy eliminates the need for external reductants and substantially reduces environmental impacts, offering a sustainable route for converting cobalt slag into recyclable catalysts for antibiotic wastewater treatment. Download: Download high-res image (176KB) Download: Download full-size image
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WATER RESEARCH
·
2025
·
IF 12.4
Zhiqiang Zuo,Yiying He,Miao Guo,Tao Liu,Min Zheng,Yanchen Liu
Ferrous-based iron salts (e.g., FeCl 2 ) have been commonly used for sulfide control in sewers, where they chemically generate ferrous sulfide (FeS) particles to remove dissolved sulfide. This study demonstrates that oxidation of FeS particles in sewer sediments can further enhance sulfide removal, likely due to the formation of hydroxyl radical (•OH) during FeS oxygenation. For the first time, an integrated kinetic model was developed to describe •OH production and consumption by FeS oxygenation in sewer environment. The model was validated against three independent sets of batch experiments, including (1) dynamics of •OH production from FeS oxygenation, (2) dynamics of •OH production from sewer sediment oxygenation, and (3) sulfide removal under various conditions. Model-based analysis identified three key sulfide chemical oxidation pathways (•OH, Fe (III), O 2 ), with the •OH pathway significantly contributing 63–97 % of sulfide oxidation in gravity sewers with surface reaeration. An empirical function ( a × C FeS b ) was further introduced to quantify the influence of FeS on sulfide oxidation rates, which can be integrated into existing sewer management models for improved control strategies. Overall, this work identifies •OH oxidation as a dominant pathway for sulfide removal in ferrous-dosed sewers, challenging the traditional view that oxygen is the primary driver of sulfide oxidation.
研究领域:
环境工程
·
化学工程
·
水处理
·
无机化学
·
建模与仿真
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PubMed
高影响因子
危险品化学品经营许可证（带存储）