ANALYTICA CHIMICA ACTA
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2023
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IF 6.2
Dandan Song,Xiaoyue Xu,Xingge Huang,Guoqiang Li,Xiaotong Wang,Yisong Zhao,Faming Gao
Heteroatom doped graphdiyne (GDY) has been demonstrated to be an effective strategy for achieving outstanding electrochemical properties, including improved electrocatalytic activity , tunable electronic properties and high electronic conductivity, by producing numerous heteroatomic defects as well as active sites. Extensive efforts have been devoted to the issue of single element doping of GDY. Introducing two or more kinds of heteroatoms into GDY materials may create a synergic effect between the co-dopants, thus generating superior electrochemical performance. Nevertheless, little research on multiple elements co-doped GDY, especially in the application of constructing electrochemical biosensor . Herein, nitrogen and fluoride co-doped GDY (N–F-GDY) has been synthesized and employed to combine with NiCo 2 O 4 –Co 3 O 4 hollow multishelled nanocages to establish an ultrasensitive electrochemical biosensor for the assay of pesticide residue . The as-prepared electrochemical biosensor possesses a wide linear range of 0.448 pM–44.8 nM for monocrotophos detection and a low detection limit of 0.0166 fM (S/N = 3).
研究领域:
材料科学与工程
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环境科学
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分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MATERIALS & DESIGN
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2023
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IF 8.4
Hao Wang,Xinyu Xu,Xiaohan Mei,Dapeng Zeng,Boda Ying,Zehao Yu,Shibo Liu,Ruiyan Li,Yanguo Qin
Bone implants that promote osseointegration and have antimicrobial capabilities are necessary to ensure optimal long-term functionality of implants. In this study, a porous composite osteogenic scaffold was prepared using a twin-screw extruder and a fused deposition modeling three-dimensional (3D) printer. A polydopamine (PDA) coating was used to load graphdiyne oxide (GDYO) on the surface of the 3D printed polyetherimide-tricalcium phosphate (PEI-TCP) osteogenic scaffold through π–π double-bond interactions. The resulting P-T-GDYO composite scaffold was characterized, and its mechanical properties, ability to promote osteogenic differentiation, and light-responsive antibacterial activity were evaluated. When the scaffold was doped with 10 wt% β-TCP, its mechanical properties remained in the range of those of cancellous bone. In terms of osteogenic differentiation, the P-T-GDYO composite scaffold promoted adhesion and osteogenic differentiation of MC3T3-E1 cells, as well as effectively promoting endogenous bone regeneration of rabbit femoral condyle bone defects in osteogenesis experiments in vivo . In a mouse subcutaneous infection model, after near-infrared light irradiation, P-T-GDYO showed an antibacterial rate of 90.18 % against Staphylococcus aureus , while maintaining good tissue–organ compatibility. This study represents an important development in GDYO-based photothermal antibacterial materials in the field of orthopedics and expands its application in the biomedical field.
研究领域:
生物材料学
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骨科医学
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组织工程学
✓ 已验证
产品关联
DOI
高影响因子
Advanced Fiber Materials
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2025
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IF 21.3
Pei Yanchun,Wu Xueyan,Ren Zhichao,Lv Yan,Xue Rui,Guo Jixi,Jia Dianzeng
Electrospun fiber membranes enable oil–water emulsion separation via tunable morphology and chemistry, yet most face an efficiency–permeability trade-off where enhancing one compromises the other. Herein, optimized membranes (C-NFO@GDY) are synthesized with a uniform honeycomb nanostructure of graphdiyne (GDY) on flexible coal-based preoxidized fibers (C-NFO) through the Glaser‒Hay coupling reaction. The honeycomb nanostructure of GDY effectively disperses external stress on the C-NFO fibers, increasing the tensile strength from 2.8 to 3.2 MPa. In addition, the nanostructure enhances hydration layer formation kinetics, achieving superhydrophilicity (0°) and underwater superoleophobicity (> 150°) of the membrane. When tested against three surfactant-stabilized emulsions (cetyltrimethylammonium bromide (CTAB), sodium dodecyl sulfate (SDS), and polyoxyethylene sorbitan monooleate (Tween 80)), the membranes demonstrated separation fluxes of 2936 L/(m 2 h), 2149 L/(m 2 h), and 1855 L/(m 2 h), and the corresponding separation efficiencies were 99.6%, 96.6%, and 93.1%. For CTAB-stabilized emulsions, the C-NFO@GDY membrane (zeta potential: − 65.2 mV) exhibits strong electrostatic attraction with cationic surfactants, achieving a high flux of 2936 L/(m 2 h) and a separation efficiency of 99.6%, surpassing those of recently reported MXene and PANI composites under identical conditions. Overall, the synergy between honeycomb nanostructure and electronegativity of GDY overcomes the flux–efficiency trade-off, offering new ideas for the preparation of oil–water separation membranes. Graphical
研究领域:
材料科学
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环境工程
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2024
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IF 8.1
Xu Kong,Kai Wang,Zhiliang Jin
More efficient hydrogen production can be achieved by rationally designing heterojunction photocatalysts and constructing interactions between photocatalysts. Herein, The CoP/Cu 3 P (Co–Cu–P) nanocubes were designed using Prussian blue analogue (PBA) as a template through the calcination phosphating method. The novel crystalline-amorphous Co–Cu–P/GDY p-n heterostructures photocatalyst was prepared by a stir-assisted low-temperature water bath method. Under visible light irradiation, the hydrogen evolution efficiency of the Co–Cu–P/GDY-3 heterostructures reached 4790.0 μmol g −1 h −1 , surpassing that of GDY (523.9 μmol g −1 h −1 ) and Co–Cu–P (2458.5 μmol g −1 h −1 ). The remarkable hydrogen evolution activity of the composite catalyst can be attributed to the presence of p-n heterojunction, while the crystalline-amorphous structure promotes efficient interfacial charge transfer. Additionally, the rough and porous nature of the Co–Cu–P/GDY heterostructures surface facilitates mass transfer and hydrogen diffusion during photocatalysis. The charge transfer pathway of the p-n heterojunction was confirmed through various characterizations, including photoluminescence spectroscopy (PL), ultraviolet photoelectron spectroscopy (UPS), valence band X-ray photoelectron spectroscopy (VB-XPS), density functional theory (DFT) calculations, and other relevant techniques. This study offers a fresh perspective on designing PBA derivatives with graphdiyne (GDY) to construct heterostructure photocatalysts for enhanced photocatalytic performance.
研究领域:
材料科学
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光催化
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能源化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
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2023
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IF 4.5
Haifeng Yao,Yahui Zhang,Yongping Dong,Mingfu Ye
Graphdiyne (GDY) is considered as another promising carbon material in biosensing field. However, the application of GDY in ECL sensing is in its infancy stage, and different roles of GDY are urgent to be discovered. In this work, strong anodic Ru(bpy) 3 2+ electrochemiluminescence (ECL) was obtained at a cucurbit[8]uril (Q[8]) modified electrode. Although GDY exhibited electrocatalytic effect on the oxidation of Ru(bpy) 3 2+ , an apparent inhibiting effect of GDY on the ECL signal was observed due to the energy transfer. An “on-off-on” mode ECL sensor was fabricated to detect pancuronium (PMD) based on the competitive host–guest interaction between ferrocene (Fc), PMD and Q[8]. Fc modified single-stranded DNA was immobilized onto the surface of GDY, which could be attached onto the electrode through the interaction between Fc and Q[8]. The quenching effect of GDY could apparently decrease ECL signal. PMD exhibited stronger combining ability with Q[8] than Fc, and could replace Fc from the cavity of Q[8], leading to the recovery of ECL signal. The variation of ECL intensity changed linearly with the PMD concentration in the range of 10 nM to 50 μM with a detection limit of 5 nM (3σ). The proposed sensor has high sensitivity, outstanding specificity and accuracy, indicating that GDY has promising potential application in ECL sensing field based on its inhibiting effect.
研究领域:
分析化学
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生物传感
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2021
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IF 13.273
Jiani Xie,Maoru Zhao,Chengyan Wang,Shuang Zhu,Wenchao Niu,Yuan Yong,Lina Zhao,Zhanjun Gu
Skin radiation damage is one of the most common illnesses in external beam radiotherapy. One of the vital reasons for the damage occurrence is the low-energy X-rays contained in treatment radiations, which are greatly absorbed by skin to cause severe skin injury. Thus, the physical prevention that shields the harmful low-energy X-rays may be an effective skin radioprotective approach. However, at present, the existing commercial skin radioprotective drugs mainly adopt a single chemical repair pathway to eliminate the intracellular toxic free radicals and usually have limited treatment outcomes. Therefore, in order to improve the therapeutic effects of radiodermatitis during radiotherapy, we attempt to design a new drug that possesses dual-mode physical prevention and chemical repair approach to enhance skin radioprotection efficacy. Herein, we for the first time design and synthesize nanosized graphdiyne-loaded sodium hyaluronate hydrogel ( [email protected] hydrogel), which possesses powerful broad-spectrum free radical scavenging activity by the nano-GDY and good low-energy X-ray attenuation ability by the hydrogel with high water content. The experimental results indicated that [email protected] hydrogel exhibits good biosafety, and can effectively decrease the low-energy X-ray-induced edema and ulcers of skin in mice, mitigate pathological lesion, reduce skin damage time and promote wound recovery.
研究领域:
放射肿瘤学
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纳米技术
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药学
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材料科学
✓ 已验证
DOI
高影响因子
ANALYTICA CHIMICA ACTA
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2022
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IF 6.911
Yang-Yang Hou,Wan-Zhen Xie,Xuecai Tan,Ke-Jing Huang,Jing Xu
A highly sensitivity self-powered biosensor is developed based on T7 exonuclease (T7 Exo) and 3D DNA walker induced rolling circle amplification (RCA) for electrochemical/colorimetric dual-mode detection of microRNA-21 (miRNA-21) with improved reliability. Taking its advantage of fascinating properties, such as high structure defects and good conductivity , graphdiyne is prepared and used to prepare high-performance enzyme biofuel cell. T7 Exo-assisted 3D DNA walker target recognition triggers RCA reaction to obtain a significantly amplified signal response. A capacitor is integrated to the enzyme biofuel cell to further amplify the electrochemical output signal of the self-powered biosensor. In detection system, glucose oxidase catalyzes glucose oxidation to produce hydrogen peroxide, and 3,3′,5,5′-tetramethylbenzidine (TMB) is then catalyzed to generate colored products, so as to achieve the colorimetric detection of the target. Analysis signals of diverse modes are recorded independently. Consequently, detection of microRNA with improved reliability and wider signal response range are achieved by electrochemical/colorimetric dual-mode with detection limits of 0.15 and 33 fM ( S/N = 3) respectively. In addition, the proposed self-powered biosensor successfully applied for the detection of miRNA-21 in human serum samples, confirming its practical applicability in clinical diagnosis. It is powerfully anticipated the proposed self-powered biosensor possesses great potential to be applied to other biomedical domains.
研究领域:
生物化学
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分子生物学
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生物医学工程
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分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）