Hu Wang,Cungang Xu,Xia Zhang,Dongmei Zhang,Fan Jin,Yuhua Fan
Six novel complexes, [Ni(C 36 H 34 N 2 O 10 )]·2.25CH 3 OH·0.5C 4 H 10 O ( 1 ), [Co(C 36 H 34 N 2 O 10 )] ( 2 ), [Cu(C 36 H 34 N 2 O 10 )]·2CH 3 OH ( 3 ), [Ni(C 36 H 32 N 2 O 8 Cl 2 )]·2CH 3 OH ( 4 ), [Co(C 36 H 32 N 2 O 8 Cl 2 )]·4CH 3 OH ( 5 ) and [Cu(C 36 H 32 N 2 O 8 Cl 2 )]·2CH 3 OH ( 6 ) with two sexidentate N 2 O 4 -donor bis-Schiff base ligands (C 36 H 34 N 2 O 10 = 1,2-bis(2-methoxy-6-formylphenoxy)ethane- l -tyrosine; C 36 H 32 N 2 O 8 Cl 2 = 1,2-bis(2-methoxy-6-formylphenoxy)ethane- l -4-chlorophenylalanine) have been synthesized and structurally characterized. Theoretical calculation of the six complexes was carried out by density functional theory (DFT) Becke's three-parameter hybrid (B3LYP) method employing the 6-3lG basis set, indicating that the calculation results are in accordance with experimental results. Moreover, the inhibitory activities of complexes 1 – 6 were tested in vitro against jack bean urease . At the same time, molecular docking was investigated to determine the probable binding mode. The experimental values and docking simulation exhibited that complexes 3 and 6 showed strong inhibitory activity (IC 50 = 10.36 ± 1.13, 15.63 ± 3.04 μM) compared with the positive reference acetohydroxamic acid (IC 50 = 26.99 ± 1.43 μM). Their structure-inhibitory activity relationship was further discussed from the perspective of molecular docking and theoretical calculation.
The escalating demand for cobalt in modern industry necessitates the recycling or extraction of this resource for sustainable development. Despite the abundance of lignin in nature, its utilization remains low, highlighting the need to enhance its value-added potential. This study focuses on the synthesis of quaternary ammonium lignin (QAL) and 2-ethylhexyl phosphoric acid mono-2-ethylhexyl ester (P507) as ionic liquid (QP–IL) compounds for the extraction of metal ions. A comparison of the extraction behavior of Co(II) and Ni(II) from chloride solution between QP–IL and P507 revealed varying extraction ratios under different conditions, with QP–IL demonstrating a higher cobalt extractability than P507. Furthermore, under identical conditions, QP–IL exhibited superior Co/Ni separation performance (βCo/Ni) compared to P507. Ultimately, QP–IL proved to be more effective than P507 in separating cobalt from mixed solutions.
Xiao-Yan Xin,Qing-Li Yu,Min Wang,Jing-Yu Guo,Shu-Xuan Wang,Na Qiao,Zhi-Qiang Wang,Wen-Min Wang
A novel Ni 8 cluster with the molecular formula [Ni₈(L 2− ) 8 (CH 3 OH) 2 ] ( 1 ) (H 2 L = (E)-2-((5-bromo-2-hydroxybenzylidene)amino)-6-methoxybenzoic acid) has been synthesized by one-pot condensation and coordination self-assembly and structurally characterized. X-ray diffraction analysis reveals that cluster 1 displays a linear-shaped octanuclear structure and each central Ni(II) ions in 1 adopt a distorted octahedron coordination geometry. Catalytic performance studies indicates that cluster 1 can effectively convert CO 2 with epoxides forming cyclic carbonates under mild reaction conditions. What's more, cluster 1 as heterogeneous catalyst can be reused at least five times with a negligible loss of catalytic activity.
危险品化学品经营许可证（带存储）