BIOSENSORS & BIOELECTRONICS
·
2024
·
IF 10.7
Anni Cui,Lihua Dong,Yiting Hou,Xin Mu,Yu Sun,Huan Wang,Xiahua Zhong,Guiye Shan
Sensitive detection and effective inactivation of bacteria are essential in preventing foodborne bacterial infection that poses a significant threat to human health. Herein, a near-infrared (NIR)-driven multifunctional photoelectrochemical (PEC) biosensor was constructed for detection and inactivation of S. aureus . Based on the covalent bonding between amine and carboxyl groups, carboxyl-functionalized SA31 aptamer was immobilized on the PDA/MnO 2 photoelectrode. In the presence of S. aureus , SA31 aptamer can specifically capture S. aureus , causing the decrease of photocurrent signal owing to steric hindrance effect. Leveraging photocurrent-off signal, there existed a satisfied linear relationship between the photocurrent variation and the logarithm of S. aureus concentration, achieving a wide linear range from 10 to 10 7 CFU/mL with a low detection limit of 2.0 CFU/mL. Notably, PDA/MnO 2 with peroxidase-like activity facilitated the catalytic oxidation of S. aureus with assistance of hydrogen peroxide (H 2 O 2 ) to cause the inactivation of S. aureus . Desorption of inactivated S. aureus from the photoelectrode led to a recovery of photocurrent signal, enabling a "signal on" switch. Simultaneously, the excellent photothermal performance of the PDA/MnO 2 converted light energy into heat energy under the irradiation of NIR light (808 nm, 1.5 W/cm 2 ), triggering the synergistic antibacterial effect against S. aureus (97.36%). This work provides a novel strategy for fabricating the detection and inactivation of bacteria in practical applications.
研究领域:
生物传感技术
·
微生物学
·
食品安全
·
医学工程
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产品关联
DOI
PubMed
高影响因子
FUEL
·
2022
·
IF 8.035
Yewen Zhang,Huiling Du,Jie Lu,Zhuo Li,Tong Lu,Yuxuan Hu,Yitian Ma
Ga 2 O 3 is widely used as anode material for lithium-ion batteries owing to its high theoretical capacity. However, Ga 2 O 3 has the disadvantages of limited electronic conductivity and severe volume expansion, which seriously restrict its application. Therefore, the Ga 2 O 3 nanospheres were coated with carbon using dopamine hydrochloride as the carbon source, which could self-polymerize along the surface of the Ga 2 O 3 particles, forming a uniform carbon coating layer, resulting in superior overall electrochemical performance. Moreover, this particular pomegranate-like morphology and carbon-coating treatment not only shorten the ion transmission path and improve the cycle stability but also provide abundant lithium-ion storage space inside the particle, which improves the pseudocapacitive storage characteristics. High capacitive contribution ratios were obtained for Ga 2 O 3 @PDA-C at different scan rates; these ratios were found to be much higher than those for Ga 2 O 3 electrode at different scan rates; the pseudocapacitance of Ga 2 O 3 @PDA-C increased to 69% and the more enormous capacitance contribution indicates its high capacity. Under the synergistic effect of multiple effects, the Ga 2 O 3 @PDA-C composite electrode exhibited excellent performance, with an initial capacity of 1863.9 mAh/g and maintained 1059.7 mAh/g after 100 cycles.
研究领域:
材料科学
·
电化学
·
能源存储
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产品关联
DOI
高影响因子
MICROPOROUS AND MESOPOROUS MATERIALS
·
2023
·
IF 5.2
Zefen Wang,Siyuan Liu,Qian Zhou,Pengru Liu,Dankui Liao,Ping Lan,Bo Peng,Xiongdiao Lan
Immobilized angiotensin converting enzyme (ACE) utilizes specific interaction between ACE and ACE inhibitors to screen drugs for hypertension therapy, but traditional immobilized ACE is insufficient to achieve satisfactory effect for the poor immobilization efficiency and stability. In this work, mesoporous ZIF-8 (mZIF-8) coated with polydopamine (PDA) was developed as an enzyme-immobilization platform for the first time. Molecular docking was used to study the mechanism of ACE induced mZIF-8 synthesis. The immobilized enzyme ACE@mZIF-8/PDA were shown to possess mesoporous structures with ACE encapsulation efficiency of ∼90%. Compared with the free enzyme, ACE@mZIF-8/PDA exhibited enhanced tolerance to temperature, pH, unfolding and proteolytic agents, with excellent reusability (maintained 82.29% ± 4.11% of initial activity after being reused 10 times) and storage stability (retaining 93.12% ± 3.271% residual activity after 30 days). Molecular docking research conformed ACE induced the triggered nucleation of MOFs via binding with MOFs precursors. Moreover, ACE@mZIF-8/PDA was used as high-performance adsorbent for enrichment of ACE inhibitory peptides. The noncompetitive inhibitory peptide GF-6 and competitive inhibitory peptide VPP could be captured synchronously, which avoided the loss of active substances. These results indicated that the ACE@mZIF-8/PDA provides an evolutionary platform for rapid screening of inhibitory peptides.
研究领域:
生物化学
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材料科学
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药物开发
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产品关联
DOI
高影响因子
ACS Sustainable Chemistry & Engineering
·
2020
·
IF 7.632
Yuhui Xie,Weijie Li,Haowei Huang,Dexuan Dong,Xinya Zhang,Li Zhang,Ying Chen,Xinxin Sheng,Xiang Lu
Phase change materials with desirable light-thermal conversion ability are particularly attractive for solar energy harvesting and storage. Herein, we demonstrate that the combination of efficient light-thermal conversion, excellent thermal property, and reliability can be achieved via the construction of a novel form-stable phase change composite material, that is, Radish@PDA/PEG with a sandwich structure. A 3D porous structure derived from radish via freeze-drying is adopted as the substrate; then, self-polymerization of dopamine is initiated in the surface of Radish to produce a layer of polydopamine (PDA). Finally, polyethylene glycol (PEG) impregnation via vacuum infusion is applied to form the Radish@PDA/PEG composite. These results prove that the incorporation of interlayer PDA can not only improve the strength of the porous structure to protect the PEG from leakage, but also enhance the encapsulation capacity of PEG and light absorption ability of the composite. The preparation method is based on common biomass with green chemicals and thus provides a general way to prepare eco-friendly and biodegradable composite with promising applications in light thermal energy management.
研究领域:
材料科学
·
能源工程
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环境科学
·
可持续材料
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产品关联
DOI
高影响因子
CORROSION SCIENCE
·
2024
·
IF 7.4
Xin Yuan,Rongcao Yu,Yilin Du,Bing Lei
To evaluate the barrier properties of the composite coatings reinforced by PDA (polydopamine)-BN@ZnO nano-pigments, the correlation between electrolyte transport characteristics and different nano-pigment contents in the composite coatings was studied. The electrochemical response of composite coatings was mainly controlled by non-Faraday process. A two-layer model based on Young's impedance was established to fit the non-Faraday process of the composite coatings from the 6th day of immersion. The coating resistivity varying with electrolyte transport could be used as a key parameter to describe the barrier properties of the coatings. At the same time, the explanation that different contents of nano-pigments enhance or weaken the barrier performance of composite coatings was given, that is, the nanoconfinement effect of the polymer under the effect of nano-pigments.
研究领域:
材料科学
·
电化学
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产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Xiaotong Mu,Wenbo Han,Hongpeng Zhang,Rui Li,Chenzhao Bai,Wei Li,Yucai Xie,Yu Liu
Interfacial solar-driven water evaporation technology is considered a cost-effective strategy to mitigate the shortage of freshwater resources at present. However, the coordinated regulation of thermal and water management remains a significant challenge in the design of evaporation systems. From the practical application viewpoint, it is essential to develop an economical, expandable, and simple preparation process for high photothermal conversion capacity and super hydrophilic evaporators. Here, a novel all-in-one MXene/PDA@MF-EF solar evaporator with a porous semi-cladding structure was designed by embedding EPE foam as a base layer (named MF-EF) inside a melamine foam (MF) and coating MXene/PDA as a light-absorbent layer on the surface of MF-EF (named MXene/PDA@MF-EF). The designed MXene/PDA@MF-EF vaporizer has excellent photothermal conversion capability and water transport channel. The MXene/PDA@MF-EF evaporator exhibits an evaporation rate reaching 1.5576 kg m −2 h −1 and a photothermal conversion efficiency of 92.63 % under 1 kW m −2 irradiation. Meanwhile, it exhibits good long-term stability and salt resistance when continuously treating seawater and different concentrations of NaCl solutions. For practical application, an outdoor evaporation device was designed, and the maximum freshwater production of up to 7.170 kg m −2 was achieved under 9 h of sunlight. Hence, the MXene/PDA@MF-EF evaporator enables clean water production through the coordinated action of thermal and water management, providing a viable and stable alternative to solar water evaporation in a variety of aqueous environments. Further, it provides a solution for realizing solar-driven interfacial evaporation desalination technology for freshwater access in coastal and offshore islands.
研究领域:
材料科学
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环境科学
·
能源工程
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产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2025
·
IF 2.5
Limei Yang,Ye Liu,Rongxue Wang,Linqian Hou,Yaling Yang
A K-doped carboxylated polydopamine (PDA) modification of the g-C3N4 (K-g-C3N4@PDA) nanozyme was effectively performed by one-step potassium salt-assisted thermal copolymerization and hydrothermal strategies. K-g-C3N4@PDA showed excellent peroxidase (POD)-like activity, and ferric ammonium citrate (FAC) efficiently promoted the generation of hydroxyl radicals (˙OH). Furthermore, K-g-C3N4@PDA oxidized 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) in the presence of H2O2 to produce a blue-green product, and FAC boosted the POD-like activity with an exceptional linear relationship and low detection limit (0.018 μg mL−1). Importantly, a recovery rate of 94.09–105.17% was attained when the developed method was effectively used to assess FAC in culinary salt samples using a spiking procedure.
研究领域:
纳米技术
·
分析化学
·
酶模拟物
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食品安全
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材料科学
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产品关联
DOI
高影响因子
Biomaterials Science
·
2019
·Vol. 8
·期 1
·391-404
·
IF 5.251
Guannan Zhang,Xingyu Zhang,Yongqiang Yang,Ruifang Chi,Jing Shi,Ruiqiang Hang,Xiaobo Huang,Xiaohong Yao,Paul K. Chu,Xiangyu Zhang
Prevention of bacterial infection and promotion of osseointegration are two important issues for titanium (Ti) implants in medical research. In addition, after a biofilm is formed on the surface of implants, the immune system and antibiotic therapy may fail. In this work, bio-functionalized titanium dioxide (TiO2)/molybdenum disulfide (MoS2)/polydopamine (PDA)/arginine-glycine-aspartic acid (RGD) nanorod arrays (NAs) are prepared on Ti implants to not only kill bacteria noninvasively upon co-irradiation of 660 nm visible light (VL) and 808 nm near infrared (NIR) light, but also promote the osteogenic activity simultaneously. Dual light irradiation triggers the TiO2/MoS2 NA to generate hyperthermia and reactive oxygen species (ROS) in 10 min. The synergistic effects of the generated hyperthermia and ROS increase the bacterial membrane permeability and bacteria are killed rapidly and efficiently in vitro and in vivo. The biofilm is also eradicated and RGD on the nanorods improves cell adhesion, proliferation, and osteogenic differentiation. The strategy described here for the design of bio-functionalized coatings on Ti implants has great clinical potential in orthopedics, dentistry, and other medical fields.
研究领域:
生物材料
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纳米技术
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生物医学工程
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骨科
·
牙科
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2025
·
IF 4.1
Qing Fu,Xuhuai Fu,Jinzhou Feng,Jing Wang,Jinyu Jiang,Shijia Ding,Daobin Han,Manxia Wang
Neuromyelitis optica spectrum disorder (NMOSD) is a central nervous system demyelinating disease that typically causes severe visual impairment and paralysis, and the aquaporin-4 antibodies (AQP4-IgG) serve as its specific diagnostic marker. In patients presenting with typical NMOSD symptoms, a positive AQP4-IgG result is sufficient to confirm the diagnosis. However, current clinical methods for detecting AQP4-IgG suffer from limited sensitivity, time-consuming procedures, and labor-intensive workflows, underscoring the urgent need for more efficient and reliable diagnostic approaches. To address these limitations, we report a novel electrochemical biosensor leveraging a hierarchical ZIF-67@PDA@PtCu nanozyme for ultrasensitive and rapid AQP4-IgG detection. ZIF-67@PDA@PtCu, a composite material consisting of a ZIF-67 core coated with polydopamine (PDA) and further decorated with PtCu nanoparticles, was utilized as a signal amplification component. The PtCu alloy nanoflowers demonstrated exceptional catalytic activity, which was further amplified by the sturdy ZIF-67 framework that enabled the integration of additional functional materials. In parallel, PDA enhanced the synergy between the unsaturated edge sites of the metal-organic framework and the outstanding catalytic properties of the PtCu alloy, thereby boosting the overall performance of the system. The integration of graphene oxide (GO) and gold nanoparticles (AuNPs) enhanced electrical conductivity. This configuration enabled efficient electrochemical (EC) signal generation, facilitating the detection of AQP4-IgG with high stability, a broad detection range of 0.1–80 U mL −1 , and an impressively low detection limit of 0.05 U mL −1 . Our findings offer a novel approach for the early diagnosis of NMOSD and provide valuable insights into the detection of other antibody-dependent neuroimmune disorders.
研究领域:
免疫学
·
神经病学
·
生物医学工程
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产品关联
DOI
高影响因子
Journal of Magnesium and Alloys
·
2025
·
IF 13.8
Xiaomeng Yu,Yuejun Ouyang,Jilan Long,Dan Xu,Guangming Liang,Zhiyuan Feng,Dongmei Pu,Qiwen Yong,Zhi-Hui Xie
Conventional nanoparticles incorporated into epoxy coatings suffer from poor compatibility and insufficient corrosion improvement, hindering their practical applications. A dual-strategy approach integrating in-situ host–guest nanoconfinement and surface self-assembly was devised to fabricate 8HQ@ZIF-8/PDA smart nanocontainers. The guest 8-hydroxyquinoline (8HQ) was encapsulated within the zeolitic imidazolate framework-8 (ZIF-8) host, leveraging nanoconfinement effects. A bioinspired polydopamine (PDA) layer was then self-assembled on the 8HQ@ZIF-8 surface through dopamine oxidative self-polymerization, resulting in a robust nanocontainer architecture. Density functional theory (DFT) calculations verify that the molecular interactions between the PDA and the ZIF-8 surface was the chemical adsorption. The resultant 8HQ@ZIF-8/PDA retained the rhombic dodecahedral morphology and crystallinity of ZIF-8, demonstrating controlled pH-responsive release behavior. When incorporated into an epoxy (EP) resin matrix on magnesium alloy, the 8HQ@ZIF-8/PDA/EP smart composite coatings exhibited outstanding interfacial compatibility and long-term stability, achieving a low-frequency impedance (| Z |₀.₀₁ Hz ) of 2.49 × 10⁷ Ω cm², a maximum phase angle of 82.8°, and a breakpoint frequency ( f b ) of 63.34 Hz after 50 days of immersion in a 3.5 wt% NaCl solution. These findings highlight the exceptional self-healing and corrosion-resistant properties of the 8HQ@ZIF-8/PDA/EP smart composite coatings, underscoring its potential for protecting magnesium alloys in aggressive environments.
研究领域:
材料科学
·
防腐蚀工程
·
表面化学
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Jinghua Li,Pengshan Guo,Shegan Gao,Jianping Wang,Ji Cheng,Wenxuan Fan,Xiaoran Liu,Xiaozhi Zhang,Kun Lei
Bacterial infection significantly hinders the wound healing process. Overuse of antibiotics has led to the rise of drug resistance in bacteria, making the development of smart medical dressings that promote wound healing without antibiotics, a critical need. In this study, Cu₂O-SnO₂-PDA (PCS) nanoenzymes with Fenton-like activity and high photothermal conversion efficiency were developed. These nanoenzymes were then incorporated into a hydrogel through cross-linking of acrylamide (AM) and N-[Tris-(hydroxymethyl)methyl] acrylamide (THMA), forming a tough, highly-adhesive, and self-healing composite hydrogel (AT/PCS) with antimicrobial properties. The AT/PCS hydrogel exhibits excellent mechanical strength and adhesion, facilitating increased oxygen levels and strong adherence to the wound site. Moreover, it effectively regulates the wound microenvironment by combining synergistic chemodynamic therapy (CDT) and photothermal therapy (PTT) for antibacterial treatment. The AT/PCS hydrogel enhances collagen deposition and expedites wound healing in a rat model, largely due to its potent antibacterial properties.
研究领域:
材料科学
·
生物医学工程
·
纳米技术
·
伤口愈合
·
抗菌治疗
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Chunqing Yang,Dongzhi Zhang,Weiwei Wang,Jun Wang,Yukun Liu,Lina Zhou,Yihong Guo,Jiahui Shao
In recent years, smart textiles and flexible wearable products have garnered significant attention in fields such as human-computer interaction, medical rehabilitation training, and motion monitoring. Flexible pressure sensors have attracted significant attention due to their excellent flexibility, stability, and multifunctional integration. Herein, a multifunctional wearable MXene/polydopamine (PDA)@cotton fabric pressure sensor was developed by modifying weft-knitted cotton fabric based on a dual hydrogen bond self-assembly strategy. The MXene/PDA@cotton fabric pressure sensor demonstrates wide linear detection range (0–146 kPa), high sensitivity (0.95 kPa–1), fast response/recovery times (16.434 and 11.952 ms), and outstanding stability after over 5000 cyclic tests. This sensor can achieve the monitoring of physiological parameters for human state detection, such as facial expression signals, abdominal respiratory signals, and joint bending signals. Furthermore, by integrating the MXene/PDA sensors into the interphalangeal and metacarpophalangeal joints of a cotton glove, combined with intelligent algorithms and the human-computer interaction system, static gesture recognition and dynamic sign language translation were successfully realized based on the smart glove. This work demonstrates the potential application of flexible pressure sensors in intelligent human-computer interaction, providing new insights for developing next-generation sign language recognition systems.
研究领域:
材料科学
·
纳米技术
·
可穿戴电子器件
·
人机交互
·
人工智能
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）