Coatings
·
2020
·Vol. 10
·期 5
·499
·
IF 2.436
Panjie Guo,Fen Wang,Tongtong Duo,Zhihong Xiao,Airong Xu,Rukuan Liu,Chaohui Jiang
With the rapid exhaustion of fossil resources, and environmental pollution relative to the use of fossil-based products, developing eco-friendly products using biomass and/or biodegradable resources is becoming increasingly conspicuous. In this study, ecofriendly and biodegradable composite membranes containing varying MC/PLA (methylcellulose/polylactic acid) mass ratios were prepared. The properties and structures of the MC/PLA membranes were studied by mechanical testing,13C NMR techniques, X-ray diffraction (XRD), thermogravimetric analysis (TGA), and hot compression. The MC/PLA membranes displayed markedly improved tensile strength and elongation at the MC/PLA mass ratio range of 99:1 to 9:1. The tensile strength and elongation of the MC/PLA (97:3) membrane was found to be the optimum, at 30% and 35% higher than the neat MC, respectively. It was also found that hot compression could improve the tensile strength and elongation of the membranes. At the same time, the membranes showed enough good thermal stability. In addition, the effect of MC/PLA mass ratio on morphologies of the membranes were studied by microscopy technique.Keywords:methylcellulose;polylactic acid;composite membrane;recyclability;improved properties
研究领域:
材料科学
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环境科学
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DOI
高影响因子
POLYMER BULLETIN
·
2017
·Vol. 75
·期 2
·533-546
·
IF 1.43
Hu Xueyan,Su Tingting,Li Ping,Wang Zhanyong
This study used benzoyl peroxide (BPO) as a cross-linking agent to modify the blends of poly(butylene succinate) (PBS) and poly(lactic acid) (PLA). The PBS/PLA blends with a ratio of 20/80 and added 1% BPO was chosen because of its favorable properties. The compatibility of PBS/PLA was improved after adding BPO. The addition of BPO also improved the crystallization and promoted the complete decomposition of PBS/PLA, respectively. The blends with BPO was degraded by proteinase K. The degradation rate of the blends reached 67% after 96 h degradation. The PLA was not degraded completely because of the crosslink between PBS and PLA.
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高影响因子
FOOD CONTROL
·
2016
·
IF 3.388
Haiyan Gao,Xiangjun Fang,Hangjun Chen,Yanhong Qin,Feifei Xu,Tony Z. Jin
Antimicrobial polylactic acid (PLA) films releasing allyl isothiocyanate (AIT) vapor were developed. The physicochemical properties and water vapor and gas permeability characteristics of the films were investigated, and the antimicrobial properties in vapor phase in food application were evaluated. The results reveal that the resultant antimicrobial (AM) PLA films had less strength, less stiffness and more flexibility, a lower O 2 and CO 2 transmission rate, and a higher UV absorption rate than the pure PLA films. Avrami’s equation showed the best fit with experimental release data (R 2 > 0.91) and indicated the release kinetics of AIT from the AM PLA film could be a combined mechanism of diffusion and first-order model. AM film treatment (4 × 8 cm film in 1 L box) significantly (p < 0.05) inhibited total aerobic bacterial growth in fresh pak choi stored at 4 and 10 °C for 15 days. The AM film treated pak choi had less color change and chlorophyll loss than the control samples during storage. The AM PLA film has the potential to be utilized for extending the shelf-life of various perishable food products.
研究领域:
食品科学
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材料科学
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DOI
高影响因子
Small
·
2024
·
IF 13
Shihao Zhang,Lei Huang,Mengxuan Bian,Lan Xiao,Dong Zhou,Ziwei Tao,Zheng Zhao,Jian Zhang,Li-Bo Jiang,Yulin Li
The use of membrane-based guided bone regeneration techniques has great potential for single-stage reconstruction of critical-sized bone defects. Here, a multifunctional bone regeneration membrane combining flexible elasticity, electrical stimulation (ES) and osteoinductive activity is developed by in situ doping of MXene 2D nanomaterials with conductive functionality and β -TCP particles into a Poly(lactic acid-carbonate (PDT) composite nano-absorbable membrane (P/T/MXene) via electrostatic spinning technique. The composite membrane has good feasibility due to its temperature sensitivity, elastic memory capacity, coordinated degradation profile and easy preparation process. In vitro experiments showed the P/T/MXene membrane effectively promoted the recruitment and osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) under ES and enhanced the angiogenic capacity of endothelial cells, which synergistically promoted bone regeneration through neovascularization. In addition, an in vivo rat model of cranial bone defects further confirmed the bone regeneration efficacy of the P/T/MXene membrane. In conclusion, the developed P/T/MXene membrane can effectively promote bone regeneration through their synergistic multifunctional effects, suggesting the membranes have great potential for guiding tissue regeneration and providing guidance for the biomaterials design.
研究领域:
生物材料学
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组织工程学
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骨科医学
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产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2019
·
IF 5.107
Ailin Gao,Guangfa Zhang,Shuai Zhao,Jian Cui,Yehai Yan
Outstanding separation properties combining high water permeability and permselectivity have always been a pursuit for porous membranes, which were commonly determined by the membrane structure and surface properties. In this work, PLA membrane with unique nanoscale bicontinuous structure was fabricated by non-solvent induced phase separation (NIPS) process involving in situ crosslinking of glycidyl methacrylate (GMA) monomers in polylactic acid (PLA) casting solution. Afterwards, systematic approaches were carried out to characterize the regulating functions of the in situ formed polymerized GMA (PGMA) on the morphology, pore shape, pore size, porosity, wettability , water flux and solutes rejection of developed PLA membranes. With the addition of GMA monomers, novel bicontinuous interconnected PLA membranes with narrowly distributed nanoscale pores were obtained. These generated PLA membranes presented higher water flux and better selective rejection to various dextran molecular owing to their larger effective pore size and narrower pore size distribution . This study provides an innovative strategy to overcome the trade-off issue when membranes are used for water treatment.
研究领域:
材料科学
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环境工程
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DOI
高影响因子
Journal of Materials Chemistry B
·
2014
·Vol. 3
·期 2
·316-322
·
IF 0
Wen-Xing Gu,Mingran Zhu,Nan Song,Xiaoxu Du,Ying-Wei Yang,Hui Gao
A series of linear and star-shaped amphiphilic polyethylene glycol block polylactide (PEG-b-PLA) and β-cyclodextrin (CD) conjugated PEG-b-PLA (PEG-b-PLA-CD) copolymers were synthesized. Bovine serum albumin (BSA) aqueous solution was emulsified in the copolymer organic solutions to fabricate reverse micelles (RMs), and was then further transferred into ethyl oleate (EO), a pharmaceutically acceptable vehicle, by the RMs. As identified by 1H NMR, the RMs were formed with a hydrophilic core of PEG and CD, covered with a hydrophobic corona of PLA moiety, and were spherical in shape, as observed by a scan electronic microscope. Compared with the PEG-b-PLA RMs, the PEG-b-PLA-CD RMs presented higher encapsulation efficiency. The release of BSA was influenced by the copolymer composition and architecture. BSA stability in the release aqueous phase was confirmed by circular dichroism spectroscopy. The oil-based formulation fabricated from biodegradable copolymers with high drug loading showed a great potential for protein delivery.
研究领域:
生物材料
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药物递送
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产品关联
DOI
PubMed
DRUG DELIVERY
·
2016
·
IF 4.843
Chang Li,Yan Shen,Chunmeng Sun,Nihad Cheraga,Jiasheng Tu
To investigate the physicochemical properties, immunosafety and chronic toxicity of monomethoxypoly(ethylene glycol)-b-poly(lactic acid) (mPEG-PLA), a copolymer used as a carrier for paclitaxel (PTX) delivery. The H-Nuclear Magnetic Resonance (H-NMR), dynamic light scattering and fluorescence probe technique were conducted to determine the physicochemical properties of mPEG-PLA copolymer. PTX-loaded polymeric micelles were characterized regarding their particle size, entrapment efficiency (EE), drug loading (DL), in vitro drug release and hemolysis rate. The complement activation in human serum and mast cells degranulation were performed by ELISA and RBL-2H3 cell line in vitro, respectively. The chronic toxicity study was carried out on beagle dogs. The optimized PTX-loaded mPEG-PLA (40/60) micelles showed a particle size of 37 nm and EE of 98.0% with a DL of 17.0% w/w. Transmission electron microscopy (TEM) analyses showed that mPEG-PLA (40/60) micelles have spherical shape with dense core. In vitro release study showed a sustained release for 24 h, and the hemolysis study revealed that mPEG-PLA (40/60) was a safe nanocarrier for intravenous administration. mPEG-PLA (40/60) showed a lower complement activation ability compared to mPEG-PLA (50/50) and Cremophor® EL (Cr EL). Furthermore, the chronic toxicity of PTX-loaded mPEG-PLA (40/60) micelles was significantly lower than those of mPEG-PLA (50/50) and Cr EL.
研究领域:
药学
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毒理学
·
纳米医学
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DOI
PubMed
高影响因子
Polymers
·
2023
·Vol. 15
·期 7
·1755
·
IF 5
Junyuan Zhang,Zilong Peng,Mengjie Wang,Yinan Li,Jinyin Wu,Yifan Jiang,Chaolong Liu,Guqiang Li,Lin Xu,Hongbo Lan
The fabrication of various 3D tissue engineering tubular scaffolds with fibrous structures, to assist the human body in rapidly repairing a variety of ailments, is receiving more and more attention. Due to the inefficiency of the majority of fibrous preparation techniques, the question of how to rapidly produce the requisite three-dimensional tubular microfiber scaffold structures has become an urgent problem. In this study, an efficient polymer fiber preparation method was developed, using a high-speed airflow drive. Melt blending of polycaprolactone (PCL), polylactic acid (PLA), and tributyl citrate (TBC), was used for the printing material, to achieve the efficient preparation of tubular microfiber scaffolds with different structures. The scaffold diameter was as small as 2 mm, the wall thickness was up to 100 μm, and the fiber injection efficiency reached 15.48 g/h. By utilizing simulations to optimize the printing parameters and by adjusting the printing settings, it was possible to achieve a controlled fiber diameter in the range of 3 μm to 15 μm. In addition, plasma treatment was applied to the microfibers’ surface, to increase their wettability, and the efficiency of the hydrophilic modification was demonstrated. Furthermore, the mechanical property test demonstrated that the fibers have a tensile strength of 1.36 ± 0.16 MPa and a tensile strain of 30.8 ± 3.5%. The radial compressive strain of the tubular scaffold could reach 60% of the original scaffold’s diameter. Finally, the in vitro degradation of the fibers at various pH values was tested. The results showed that, under alkaline conditions, the surface of the fibers would be severely crushed and the rate of deterioration would increase.Keywords:airflow-field-driven;3D printing;microfiber scaffold;polycaprolactone (PCL);polylactic acid (PLA)
研究领域:
组织工程
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材料科学
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生物医学工程
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
·
2026
·
IF 4
Aili Wang,Mengqing Qi,Jiaxing Hao,Yiyang Yu,Wenge Yang,Yonghong Hu
BACKGROUND As the demand for eco-friendly food packaging rises, biodegradable electrospun fiber membranes have attracted wide attention. However, existing single-component membranes face limitations such as insufficient mechanical properties, unstable functional release, and weak antioxidant/antibacterial activity. This work innovatively created a polylactic acid (PLA)/gelatin/ethyl cellulose ternary electrospun fiber membrane (PEG) by encasing low-cost citric acid (CA) and vitamin E/hydroxypropyl-β-cyclodextrin (VE/HP-β-CD) complexes to enhance functionality and stability. RESULTS Scanning electron microscopy showed satisfactory compatibility with uniform, defect-free fibers. Fourier transform infrared spectroscopy and X-ray diffraction confirmed the successful encapsulation of VE in HP-β-CD, and interactions with the polymer matrix altered the crystalline structure. Thermal analysis revealed enhanced thermal stability, with the decomposition temperature increasing from 340 to 349 °C. As CA and VE/HP-β-CD content increased, the membrane's contact angle decreased, elastic modulus rose (from 18.3 to 60.7 MPa), and elongation at break improved (from 53.8% to 103.7%). Functional tests showed slow continuous release of VE within 200 h, 73.9% DPPH (1,1-diphenyl-2-picrylhydrazyl) scavenging, and increased antibacterial activity. Both MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) and live/dead assays showed >90% viability for PEG films. In strawberry preservation, the membrane extended its shelf life by 8 days, improving quality. CONCLUSION These results demonstrate that the combined encapsulation of CA and VE/HP-β-CD and their interactions with the matrix successfully optimized the material structure, properties, and functionality, offering a sustainable direction for developing eco-friendly, functional packaging materials. © 2026 Society of Chemical Industry.
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PubMed
高影响因子
Materials Research Express
·
2018
·Vol. 5
·期 4
·045019
·
IF 1.151
Shu-Xin Yu,Jie Zheng,Xu Yan,Xiao-Xiong Wang,Guang-Di Nie,Ye-Qiang Tan,Jun Zhang,Kun-Yan Sui,Yun-Ze Long
In conventional solution electrospinning, the morphologies (e.g., spheres, beaded fibers, and fibers) of electrospun products can be controlled by solution concentration. Here, we report that the morphologies and structures of polylactic acid (PLA) via melt electrospinning also can be adjusted from microfibers to microspheres by simply increasing the spinning temperature. It was found that with temperature increasing from 200 °C to 240 °C, the average diameter of melt-electrospun PLA fibers decreased from 58.46 to 2.96 μm. Then, beaded fibers and microspheres about 14.5 μm in diameter were collected when the spinning temperature was increased to 250 °C and 260 °C. In addition, we also found that the average PLA fiber diameter decreased with increasing the applied spinning voltage, and increased with the increase of spinning distance. To explain the formation mechanism of different PLA microstructures, rheological property and infrared spectra of PLA under different spinning temperatures were also tested.
研究领域:
材料科学
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生物医学工程
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DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2022
·Vol. 57
·期 19
·8687-8700
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IF 4.682
Zhang Nan,Zhao Man,Liu Guangfa,Wang Jiaoyang,Chen Yunzhi,Zhang Zhengjian
A green modification method for effectively enhancing toughness of PLA was established. Herein, alkaline lignin (LG) was firstly alkylated with dodecane, and then grafted with lactide (LA). The alkylated lignin-lactide graft copolymer (GLG-g-LA) was obtained via ring-opening polymerization (ROP). GLG-g-LA copolymer can be utilized as a functional filler to toughen polylactic acid (PLA) packaging film. The 31 P-NMR of alkylated lignin (GLG) demonstrated that the peak of phenolic hydroxyl groups disappeared completely, while the relative peak intensity of carboxyl hydroxyl groups decreased significantly. The grafting rate of GLG-g-LA copolymer was improved more than twice times compared with lignin-lactide graft copolymer (LG-g-LA). Then LG-g-LA and GLG-g-LA copolymer were mixed with PLA to prepare different PLA composite films via casting method, respectively. Particularly, the elongation at break of PLA/GLG-g-LA2 composite film increased to 41.98%, which was more than 20 times higher than PLA. In general, PLA/GLG-g-LA composite film with toughness, excellent UV barrier, water resistance and controllable gas permeation could be used as high-performance and biodegradable materials in packaging field.
研究领域:
材料科学
·
绿色化学
·
高分子化学
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高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2018
·Vol. 29
·期 22
·19296-19307
·
IF 2.324
Qian Yi,Yao Zhengjun,Lin Haiyan,Zhou Jintang
3D printing technology has attracted more and more interest in rapid manufacturing of components with complex shapes by pre-design. In the present work, various content of Li 0.44 Zn 0.2 Fe 2.36 O 4 (LZFO) particles as reinforcement were added to polylactic acid (PLA) matrix for preparing 3D-printed composites by using fused deposition modeling (FDM). The structure and morphological characteristics were systematically examined by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), and Scanning electron microscopy (SEM). Furthermore, mechanical, thermal and microwave absorption properties of 3D-printed LZFO/PLA composites with different contents were investigated in detail. Tensile strength and Young’s modulus of the LZFO/PLA composite with 10 wt% LZFO content were remarkably improved than that of original PLA. Thermal stability of the composite with 5 wt% LZFO content was the best among the test specimens. Microwave absorption property suggested that the reflection loss (R L ) of the composite with 20 wt% LZFO can reach − 32.4 dB at 3.8 GHz and − 31.8 dB at 16.1 GHz with the thickness of 6 mm, and the effective bandwidth corresponding to R L (≤ − 10 dB) reaches 2.1 GHz (3.1–5.2 GHz) and 1.8 GHz (14–15.8 GHz). Therefore, 3D-printed LZFO/PLA composites prepared by FDM can be an incredibly promising novel 3D printable microwave absorption candidate with other comprehensive properties. Moreover, microwave absorbing materials prepared by 3D printing technology especially using FDM may become the development trend of this kind of materials in the future.
研究领域:
材料科学
·
电磁学
·
制造工程
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DOI
高影响因子
危险品化学品经营许可证（带存储）