Journal of Food Measurement and Characterization
·
2024
·
IF 2.9
Huang Zhiwu,Peng Qiang,Luo Xiaomin,Bi Yongguang,Kong Fansheng,Wang Zhong,Tan Shaofan,Zhang Junyong
Protein-stabilized star anise essential oil nano-emulsion (SAEO-NE) was successfully prepared using an ultrasound-assisted method to address the intrinsic defects and enhance the bioavailability of star anise essential oil (SAEO). In this study, the polydispersity index (PDI), particle size, and zeta potential (ZP) of SAEO-NE were used as performance indicators, and the optimal preparation conditions were determined to be an emulsifier dosage of 5%, an ultrasonic power of 270 W, and an ultrasonic time of 15 min. Transmission electron microscopy (TEM) and dynamic light scattering (DLS) analyses revealed that the resulting nanoparticle exhibited a uniform spherical shape, with a particle size of 246.5 ± 1.35 nm and a ZP of -38.97 ± 0.45 mV. Rheological analyses further confirmed the favorable rheological characteristics of the nano-emulsion. Moreover, SAEO-NE demonstrated robust adaptability across varying salinities (100, 200, 300, and 400 mM) and pH levels (1, 3, 5, 7, 9). After storage at 4 °C for 5 weeks, the nano-emulsion maintained particle sizes below 300 nm, indicating excellent storage stability. In addition, the in vitro antioxidant evaluation showed that SAEO exhibited enhanced antioxidant activity after nano-emulsification.
研究领域:
食品科学
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纳米技术
·
生物学
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产品关联
DOI
高影响因子
JOURNAL OF COORDINATION CHEMISTRY
·
2021
·
IF 1.751
Na Zhang,Yuying Li,Liduo Chen,Cuiqin Li,Guoliang Mao,Jun Wang
A series of star iminopyridine ligands, containing different groups (H, CH3, Br) in the pyridine ring, have been synthesized and characterized by FT-IR, 1H NMR, and UV-vis. The corresponding nickel(II) complexes have been prepared in good yields. The nature of the Ni complexes has been established by FT-IR, UV-vis, ESI-MS, and ICP. Upon activation with methylaluminoxane (MAO), the nickel complexes were able to oligomerize ethylene to produce C4–C18 fractions at activity of up to 105 g (mol Ni h)−1. The influence of substituent, catalyst structure, solvent, co-catalyst, and reaction conditions on the catalytic activity and product selectivity was investigated. The results showed that substitution on the pyridine ring had large influence on the catalytic activity and product selectivity. The catalytic activity increased at first and then decreased with the increase of reaction temperature and Al/Ni molar ratio. However, the catalytic activity continuously increased with increasing reaction pressure. When toluene was used as solvent and MAO was used as co-catalyst, catalytic activity of 4.39 × 105 g (mol Ni h)−1 and 31.93% selectivity of higher carbon olefins (C8–C18) were obtained at 10 °C, Al/Ni molar ratio 500, and the reaction pressure 1.0 MPa.
研究领域:
有机化学
·
催化化学
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产品关联
DOI
高影响因子
JOURNAL OF SOLID STATE CHEMISTRY
·
2024
·
IF 3.2
Yunchao Ma,Shengnan Qi,Yuxin Yao,Chuanxue You,Chunbo Liu,Baixiang Ren
Covalent organic frameworks (COFs) are widely used for gaseous radioiodine capture through distinctive properties. Herein, 2D fluorinated imine COF (JLNU-316) was designed and constructed in this study. JLNU-316 exhibited large BET surface area of 596.25 mg 2 /g and pore size (2.74 and 3.78 nm), excellent thermal and chemical stability. The adsorption of iodine by JLNU-316 reached 4.08 g/g, which exceeded most of the current fluorine-containing porous iodine adsorption materials. Furthermore, the iodine adsorption capacity remains at 99 % after seven days of exposure to air conditions, and JLNU-316 maintains stable performance following ten cycles. The introduction of heteroatoms enhanced the stability of JLNU-316 and enriched the adsorption sites, thereby increasing the iodine adsorption capacity. This study guides for the design and preparation of novel iodine adsorbents.
研究领域:
材料科学
·
环境科学
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产品关联
DOI
高影响因子
Polymers
·
2019
·Vol. 11
·期 10
·1574
·
IF 3.164
Yuanjie Wang,Xinzhi Liu,Liying Liu,Hui Niu
In this work, a series of isotactic-polypropylene/atactic-polystyrene (iPP/aPS) miktoarm star copolymers, PxSy, was synthesized via an arm-first approach. Varied star macromolecule architectures were fabricated by designing the arm length and the arm numbers (x and y). These miktoarm stars were able to form micelles in selective solvent (N,N′-dimethylformamide (DMF)), in which the insolubleiPP arms formed the core and the solubleaPS arms formed the shell. The miktoarm polymers aggregated to micro-nanoscale binary structures (MNBSes) in the casting process, and their morphologies, including the MNBS shape and size, were greatly influenced by the PxSyarchitectures. The MNBSes endowed the material surface with superhydrophobic performance with a water contact angle of 157.0° and a sliding angle of 1.5°.Keywords:miktoarm star copolymer;isotactic-polypropylene;atactic-polystyrene;aggregation morphology
研究领域:
高分子化学
·
材料科学
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产品关联
DOI
PubMed
高影响因子
POLYMER BULLETIN
·
2015
·Vol. 72
·期 11
·2949-2965
·
IF 1.438
Ren Qiang,Xiang Yanli,Huang Chunyan,Li Jian,Wang Chengyi
A novel epoxy resin toughener based on star-shaped copolymer of butyl acrylate (BA) and glycidyl methacrylate (GMA) [poly (BA- co -GMA)] with low viscosity was developed. The star polymers were synthesized by initiators for continuous activator regeneration atom transfer radical polymerization (ICAR ATRP) using tri, tetra and hexa-functional initiators. The branching parameters of star poly (BA- co -GMA) were characterized by gel permeation chromatography with a laser light scattering-viscometry triple detection system. Copolymer composition and glass transition temperatures of the copolymers were analyzed by proton nuclear magnetic resonance ( 1 H-NMR) and differential scanning calorimetry (DSC), respectively. The results showed that the branching ratio decreased as the number of arms increased. The epoxide groups of the GMA units were kept intact during ICAR ATRP. Rheological, mechanical tests and dynamic mechanical analysis revealed that star poly (BA- co -GMA)/diglycidyl ether of bisphenol A (DGEBA) epoxy resin formulation exhibited better processability, higher impact resistance and thermal resistance than those of linear poly (BA- co -GMA)/DGEBA epoxy resin formulation.
研究领域:
高分子科学
·
材料科学
·
化学工程
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产品关联
DOI
高影响因子
ENVIRONMENTAL TOXICOLOGY
·
2023
·
IF 4.5
Shuang Wang,Xueyan Gu,Jianhua Ma,Zhangyu Gu,Rui Zhang,Ruifen Li,Jun Bai,Peng Li,Linyu Wei,Yixing Ye,Yan Wang,Li Zhang,Li Su,Changhao Liang
The present study was designed to investigate the role of miR-708-5p/p38 mitogen-activated protein kinase (MAPK) pathway during the mechanism of selenium nanoparticles (Nano-Se) against nickel (Ni)-induced testosterone synthesis disorder in rat Leydig cells. We conducted all procedures based on in vitro culture of rat primary Leydig cells. After treating Leydig cells with Nano-Se and NiSO 4 alone or in combination for 24 h, we determined the cell viability, reactive oxygen species (ROS) levels, testosterone production, and the protein expression of key enzymes involved in testosterone biosynthesis: steroidogenic acute regulatory (StAR) and cytochrome P450 cholesterol side chain cleavage enzyme (CYP11A1). The results indicated that Nano-Se antagonized cytotoxicity and eliminated ROS generation induced by NiSO 4 , suppressed p38 MAPK protein phosphorylation and reduced miR-708-5p expression. Importantly, we found that Nano-Se upregulated the expression of testosterone synthase and increased testosterone production in Leydig cells. Furthermore, we investigated the effects of p38 MAPK and miR-708-5p using their specific inhibitor during Nano-Se against Ni-induced testosterone synthesis disorder. The results showed that Ni-inhibited testosterone secretion was alleviated by Nano-Se co-treatment with p38 MAPK specific inhibitor SB203580 and miR-708-5p inhibitor, respectively. In conclusion, these findings suggested Nano-Se could inhibit miR-708-5p/p38 MAPK pathway, and up-regulate the key enzymes protein expression for testosterone synthesis, thereby antagonizing Ni-induced disorder of testosterone synthesis in Leydig cells.
研究领域:
分子生物学
·
内分泌学
·
毒理学
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DOI
PubMed
高影响因子
CHINESE JOURNAL OF POLYMER SCIENCE
·
2025
·
IF 4
Yuan Chao-Yang,Shi Lei,Ji Shang-Chao,Chen Hai-Long,Tong Xiao,Hao Zi-Ying,Pan Xiao-Da,Yin Xian-Ze,Zheng Long
Airless tires are essential for enhancing the safety, reliability, and convenience of maintenance of electric bicycles. Polyurethane (PU) is considered a promising candidate for such applications owing to its versatile properties. However, their use is limited by insufficient heat resistance and excessive dynamic heat generation under cyclic loading. In this study, star-shaped trifunctional polypropylene glycerol (PPG3) was incorporated into conventional poly(tetramethylene glycol) (PTMG) and 4,4′-methylenediphenyl diisocyanate (MDI)-based systems to construct microporous star-shaped casting polyurethanes (SCPU), with water serving as a green foaming agent. Unlike conventional small-molecule trifunctional crosslinkers that create junctions within hard segment domains, PPG3 introduces long flexible arms between the hard segments, anchoring the crosslinking points at its molecular core. The large steric hindrance of PPG3 effectively suppresses soft segment crystallization and lowers the degree of microphase separation, whereas the crosslinked network restricts chain mobility, thereby reducing dynamic heat generation. These structural features also enhance the heat resistance, yielding a softening temperature of 183 °C, which is 30.9% higher than that of polyurethane without PPG3. When applied to airless tires by casting SCPU into rubber treads, the fabricated hybrid airless tires achieved a rolling distance of over 3000 km under a load of 65 kg at 25 km/h without structural failure, satisfying practical performance requirements. This strategy offers a simple, solvent-free, and environmentally friendly process, underscoring the potential of SCPU for scalable production of high-performance airless tires.
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产品关联
DOI
高影响因子
JOURNAL OF POLYMER RESEARCH
·
2013
·Vol. 20
·期 6
·1-10
·
IF 2.019
Yang Jiaojiao,Cao Shuqin,Xin Jianyu,Chen Xingyu,Wu Wei,Li Jianshu
Layer-by-layer (LbL) systems constructed via electrostatic attraction or other forces can be used as templates in biomimetic mineralization. In this work, 21-arm star poly(acrylic acid) (star-PAA) and 21-arm star poly[2-(dimethylamino)ethyl methacrylate] (star-PDMAEMA) were successfully synthesized from a cyclodextrin core via atom transfer radical polymerization (ATRP). The star polymers were used to construct three kinds of LbL systems: negatively charged star-PAA with positively charged chitosan (CHI) as a model of unconfined space for mineralization, and positively charged star-PDMAEMA with negatively charged poly(styrene sulfonic acid) sodium salt (PSS), which had acid-etched holes or constructed within a porous polycarbonate filters, as two different models of confined space for mineralization. Different crystal forms of calcium carbonate were obtained using the three systems, so these LbL systems assembled from star polymers could be new tools for developing functional materials and investigating fundamental aspects of the mineralization process.
研究领域:
材料科学
·
仿生学
·
化学工程
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DOI
高影响因子
POLYMER
·
2017
·
IF 3.684
Pengcheng Zhang,Zhenghe Zhang,Xiaoze Jiang,Leilei Rui,Yun Gao,Weian Zhang
A biotin-functionalized amphiphilic star-shaped block copolymer , POSS-(PCL- b -PDMAEMA) 8 -biotin, with an inorganic POSS nucleus, a hydrophobic poly( ɛ -caprolactone) (PCL) middle layer, a hydrophilic poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) outer corona was synthesized for the targeting delivery and pH-responsive release of hydrophobic pheophorbide A (PPa) photosensitizers . In aqueous solution, this amphiphilic copolymer was able to form unimolecular micelles as determined by transmission electron microscopy (TEM) and dynamic light scattering (DLS). The biotin-functionalized unimolecular micelles were responsive to pH and further utilized in encapsulation and release of PPa for photodynamic therapy (PDT). The PPa release from PPa-loaded unimolecular micelles could be enhanced at acidic condition. Additionally, confocal laser scanning microscopy (CLSM) and flow cytometry results revealed that PPa-loaded tumor-targeted unimolecular micelles could boost the internalization rate in HeLa cells effectively. Moreover, PPa-loaded unimolecular micelles showed low dark toxicity and high PDT efficacy towards HeLa cells according to the 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay. Thus, PPa-loaded POSS-(PCL- b -PDMAEMA) 8 -biotin would have presented the potential application in PDT.
研究领域:
材料科学与工程
·
生物医药
·
纳米医学
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DOI
高影响因子
Polymer Chemistry
·
2013
·Vol. 5
·期 6
·1930-1937
·
IF 5.231
Dan Li,Haolong Li,Lixin Wu
A series of hybrid supramolecular star polymers (SSPs) consisting of a polyoxometalate EuW10O369− (EuW10) core and different length of polystyrene arms have been fabricated by a “core-first” method, in which the anionic EuW10 clusters were firstly encapsulated by cationic molecules with trithioester terminal groups and subsequently polystyrene arms were grafted by reversible addition–fragmentation chain-transfer (RAFT) polymerization. The SSPs exhibit structurally dependent self-assembly behaviours in solution, at the air–water interface and solid state. It was found that the SSPs with short arms form large assemblies with a diameter over 100 nm in chloroform, while those with long arms tend to be mono-dispersed. Meanwhile, the distance between the EuW10 cores of adjacent SSPs in Langmuir monolayers and casting films can be precisely adjusted by PS arms, which leads to a tunable colour purity of EuW10 luminescence. This tight structure–property relationship enables the polyoxometalate-cored SSPs to act as potential building blocks for the construction of hybrid polymer materials with controllable functions.
研究领域:
材料科学
·
高分子化学
·
超分子化学
·
纳米材料
·
发光材料
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DOI
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 112
·111217-111225
·
IF 3.289
Sijie Zhao,Huiru Yang,Cai Zuo,Lu Sun,Liwei Ma,Hua Wei
Star-shaped polymers are attractive as drug carriers due to the integration of relatively easy synthesis compared to the preparation of hyper-branched dendrimers and their potential ability to form unimolecular nanoparticles with enhanced stability to survive the high dilution-associated deformation and subsequently premature drug release in the body fluids and blood during circulation. Clearly, the star structure exerts a significant effect on their bioproperties and potential applications. In this study, three star-shaped amphiphilic copolymers with the same polymer compositions but different star structures were synthesized to investigate the effect of star architecture on their properties as well as potential applications as drug carriers. Three different branched alcohols, 2-(hydroxymethyl) propane-1,3-diol, pentaerythritol and dipentaerythritol with 3, 4, and 6 respective hydroxyl groups were chosen as the starting core to generate the target star-shaped amphiphilic block copolymers composed of hydrophobic poly(ε-caprolactone) (PCL) and hydrophilic poly(oligoethyleneglycol methacrylate) (POEGMA) with 3, 4, and 6 corresponding star arms by a combination of ring-opening polymerization (ROP) and atom transfer radical polymerization (ATRP). Dynamic light scattering (DLS) measurements and pyrene fluorescence probe technique confirmed the capability of the resultant star-shaped amphiphilic copolymers to form unimolecular micelles with average diameters smaller than 50 nm in an aqueous phase. A comparison of the drug loading capacity revealed that the micelles of 4-star-PCL–POEGMA (4s-PCL–POEGMA) exhibited the highest drug loading content (DLC) of all the three formulations. More importantly, in vitro doxorubicin (DOX) release study showed unique pH-mediated drug release behaviors, i.e., dramatically accelerated release at pH 6.0 but a much slower profile at pH 7.4, from these generally recognized “pH-insensitive” 4-arm star-shaped micelles. An acid-triggered degradation and an acid–base titration were performed to further reveal that such interesting pH-responsive drug release behaviors were attributed primarily to the hydrophilic corona of OEG brushes. This study is believed to provide a new insight into the structure–bioproperties relationship of star-shaped polymers, thus should be useful for the future design and development of novel star-shaped polymers for controlled drug delivery.
研究领域:
高分子药剂学
·
纳米医学
·
药物控释
·
生物材料
·
药剂学
·
肿瘤治疗
·
纳米载体
✓ 已验证
DOI
高影响因子
POLYMER
·
2017
·
IF 3.684
Shilin Zhang,Tianyang Xu,Shengchao Chai,Liying Zhang,Lixin Wu,Haolong Li
Microporous films with tunable honeycomb structures were fabricated based on the self-assembly of a series of clusto-supramolecular star polymers (CSPs) guided by breath figure templates. The CSPs consist of a hydrophilic polyoxometalate cluster core and several hydrophobic polystyrene arms that are electrostatically connected to the core, in which three Keggin-type polyoxometalate clusters [CoW 12 O 40 ] 6- , [SiW 12 O 40 ] 4- and [PW 12 O 40 ] 3- were used as the cores. The dynamic bonding character endows CSPs a rearrangeable amphiphilic conformation that facilities them to accumulate at the oil/water interface to stabilize water droplets. By precisely adjusting the arm number and arm length of CSPs, we revealed the relationship between the structure and the film-forming behavior of CSPs. Regular pores with a small diameter as low as 260 nm were obtained by optimizing the structure of CSPs. Moreover, the CSPs could act as morphological modifiers to efficiently improve the microporous regularity of polystyrene films, even at a low CSP content of 0.8 wt%. To the best of our knowledge, this is the first work using supramolecular star polymers to fabricate microporous films by the breath figure method, which not only introduces a new film-formation material, but also provides a facile way to incorporate inorganic functional components into microporous polymer films .
研究领域:
高分子科学
·
材料化学
·
纳米结构制备
·
软物质物理
·
功能材料
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）