Micro & Nano Letters
·
2018
·Vol. 13
·期 10
·1386-1389
·
IF 0.841
Chenhao Zhao,Jiangshui Luo,Zhibiao Hu
Seeking for the porous carbon with suitable structure and morphology has been a key to improve the lithium storage performance of carbon/selenium composite. In this work, the hierarchical porous N,O Co-doped carbon has been prepared by an initial hydrothermal carbonisation and subsequent activation route using the chitosan as raw material. The carbon obtained at 600°C possessing primary micropores and surface macropores presents high specific surface area (809. 3 m 2 g −1 ) and low porous size, and the selenium with amorphous structure is uniformly encapsulated into the micropores of this carbon to form carbon/selenium composite. As the cathode materials of lithium ion battery, this composite delivers a discharge capacity of 446.9 mAh g −1 at rate of 0.24 C after 100 cycles. At a high rate of 4.8 C, this composite still shows a stable discharge capacity of 342.8 mAh g −1 . These results suggest that this composite may be promising for practical applications for lithium-selenium battery.
研究领域:
材料科学
·
电化学
·
能源存储
·
纳米材料
·
功能碳材料
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2018
·
IF 3.909
Lizeng Cheng,Liang Chen,Qiongqiong Yang,Yuanfeng Wang,Xinlin Wei
Selenium (Se)-containing polysaccharide, a Se-conjugate macromolecule, generally exhibited higher antitumor activity than its regular polysaccharide. Previously, we extracted Se-containing tea polysaccharides (Se-TPS) from Se-enriched tea, and explored its structure and antioxidant activity. In this study, we investigated antitumor activity of Se-TPS on sarcoma 180 (S-180), and compared with its regular polysaccharides TPS and dietary supplement Se-yeast. In vitro antitumor activity of Se-TPS was evaluated by MTT and LDH assays, and the results indicated that Se-TPS can significantly inhibit the proliferation of S-180 in dose-dependent manner (R 2 = 0.97, p < 0.0001). In S-180 cancer xenograft model in Kunming mice, Se-TPS oral administration at three doses of 50, 100 and 200 mg/kg body weight daily for 13 days resulted in significant tumor regression. At the same dose, Se-TPS exhibited significantly higher antitumor activity than TPS and Se-yeast. Importantly, Se-TPS can significantly increase the spleen and thymus indices of tumor-bearing mice, suggesting the safety and immunomodulatory activity of Se-TPS. Therefore, Se-TPS may be a desirable antitumor agent for therapeutic and immunomodulatory applications.
研究领域:
药理学
·
肿瘤学
·
免疫学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ELECTROCHIMICA ACTA
·
2026
·
IF 5.8
Yue Hao,Jingshun Liu,Zhihui Xu,Cheng Yang,ChongBo Tian,Jiafeng Cao,Xuelei Li,Aruuhan Bayaguud
A binder-free VSe-CuO@NiCo-Se electrode with selenium-rich vacancy (VSe) and hierarchical nanoarrays is constructed. • The interconnected hierarchical nanoarray structure effectively alleviate volume expansion and facilitate rapid electron/ion transport. • Se vacancies significantly enhances the electrical conductivity and creates abundant redox active sites of electrode material. • The series connection of two VSe-CuO@NiCo-Se//AC devices successfully addresses high-voltage application requirements. Sluggish kinetics and poor cycling stability of battery-type electrode materials are two major bottlenecks that limit the large-scale application of supercapacitors (SCs) in energy storage systems. To address these challenges, we designed and constructed a binder-free V Se -CuO@NiCo-Se electrode with hierarchical selenium-vacancy (V Se ) nanoarrays directly grown on a highly conductive copper foam (CF) substrate. Systematic characterizations combined with theoretical calculations reveal that the three-dimensional porous CF structure serves dual functions as both a current collector and a Cu source, which not only alleviates the agglomeration of electrode materials and but also eliminates the degradation of electrochemical performance caused by insulating binders and additives. Moreover, the interconnected hierarchical nanoarray structure effectively alleviate volume expansion during charge-discharge processes while facilitating rapid electron/ion transport. Most notably, the introduction of Se vacancies significantly enhances the electrical conductivity and creates abundant redox active sites of electrode material. As anticipated, the V Se -CuO@NiCo-Se electrode displays elevated specific capacity of 441.6 mAh g –1 (2890.9 F g –1 ) at 3 A g –1 , excellent rate capability (94.8% capacity retention at 20 A g –1 ), and long cycling stability (82% capacity retention after 10,000 cycles). Furthermore, the V Se -CuO@NiCo-Se//AC quasi-solid-state asymmetric supercapacitor device achieves an energy density of 38.4 Wh kg –1 at 800 W kg –1 . Importantly, the series connection of dual devices successfully addresses high-voltage application requirements. The strategic integration of Se vacancies, hierarchical nanoarrays, and a binder-free structure is a highly effective approach for developing high-performance electrodes, thereby advancing the practical application of SCs in energy storage. The hierarchical CuO@NiCo-Se nanoarray electrode material with Se vacancies (V Se -CuO@NiCo-Se) shows high specific capacity, excellent rate performance, and substantial durability. In addition, a quasi-solid-state asymmetric supercapacitor (ASC) constructed with V Se -CuO@NiCo-Se functioning as the positive electrode and activated carbon (AC) serving as the negative electrode manifests outstanding cyclability (75.3% capacity retention after 5000 cycles). Download: Download high-res image (258KB) Download: Download full-size image
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DOI
高影响因子
FOOD CHEMISTRY
·
2016
·
IF 4.052
Yong Fang,Zi Xu,Yi Shi,Fei Pei,Wenjian Yang,Ning Ma,Benard Muinde Kimatu,Kunlun Liu,Weifen Qiu,Qiuhui Hu
This study aimed to investigate the protection mechanism of Se-containing protein hydrolysates (SPH) from Se-enriched rice on Pb 2+ -induced apoptosis in PC12 and RAW264.7 cells. Results showed that SPHs could alleviate Pb 2+ -induced morphological changes of apoptosis and the loss of mitochondrial transmembrane potential in both cell types. Besides this, SPHs could significantly reduce the activation of caspase-3, -8, -9 induced by Pb 2+ , reverse the Pb 2+ -induced upregulation of Bax and release of cytochrome C, and downregulate Bcl-2 in cells. HPLC-ICP-MS and SEC-HPLC assays showed that SPHs were low molecular weight peptides (229.4–534.9 Da), and the major Se species found in SPHs was SeMet. Taken together, these findings suggested that SPHs could possibly protect the cells against Pb 2+ -induced apoptosis via a caspase-dependent mitochondrial pathway, and the primary effective constituents in SPHs were SeMet and Se-containing peptides, suggesting that SPHs might be a novel potential candidate to improve the health of people with Se deficiency or in Pb-contaminated areas.
研究领域:
毒理学
·
细胞生物学
·
营养科学
✓ 已验证
DOI
PubMed
高影响因子
INORGANIC CHEMISTRY
·
2019
·
IF 4.85
Mengping He,Dongxing Kou,Wenhui Zhou,Zhengji Zhou,Yuena Meng,Sixin Wu
The earth-abundant Cu2ZnSnS4 (CZTS) quantum dots (QDs) have emerged as one potential substitute to toxic cadmium or rare indium QDs, but their application in quantum dot-sensitized solar cells (QDSSCs) is still limited by the improper particle size and the rigorous synthesis and ligand exchange conditions. Herein, we developed a one-pot hot injection method by using Tri-n-octylphosphine oxide (TOPO) as the solvent and oleylamine as the capping agent to synthesize Cu2ZnSn(S,Se)4 (CZTSSe) QDs with adjustable size and narrow size distribution. The key feature of this approach is that we can take advantage of the high-temperature nucleation, low-temperature growth, and strong reducibility of NaHB4 to prepare small-sized CZTSSe QDs without using 1-dodecanethiol (DDT) and to extend the light harvesting range through Se incorporation. After Se incorporation, it turns out that the conduction band (CB) level of CZTSSe QDs decreases, implying that the injection driving force of the electron to the CB of TiO2 films becomes weaker and a larger recombination would be induced at the TiO2/QDs/electrolyte interface. Benefiting from the broadened optoelectronic response range, the induced higher Jsc (16.80 vs 14.13 mA/cm2) finally leads to the increase of the conversion efficiency of CZTSSe QDSSC from 3.17% to 3.54% without further modification. Despite the fact that the efficiency is still far behind those of literature reported values through use of other chalcogenide sensitizers, this DDT-free approach solves the main hindrance for the application of CZTSSe QDs in QDSSCs and holds a more convenient way for ligand exchange, light absorption improvement, and particle size control.
研究领域:
材料科学
·
能源技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2016
·
IF 4.052
Zi Xu,Yong Fang,Yue Chen,Wenjian Yang,Ning Ma,Fei Pei,Benard Muinde Kimatu,Qiuhui Hu,Weifen Qiu
The protective capacity of Se-containing protein hydrolysates with molecular weight below 1 kDa (SPHs-3), against Pb 2+ -induced damage in PC12 and RAW264.7 cells, was investigated in this study. The cell viability, levels of reactive oxygen species (ROS), lactate dehydrogenase (LDH), superoxide dismutase (SOD), nitric oxide (NO), malondialdehyde (MDA) and glutathione (GSH) in cell were analyzed. Results showed that 100 μg/ml of SPHs-3 pretreatment could significantly increase cell viability by 24.9% and 23.0% in Pb 2+ -treated PC12 and RAW264.7 cells, respectively ( P < 0.01). The levels of ROS, NO, LDH and MDA were reduced by 32.2%, 68.2%, 79.7% and 73.7% in 100 μg/ml SPHs-3 pretreated PC12 cells, respectively ( P < 0.01). SPHs-3 pretreatment was also associated with increases of SOD activity and GSH content in cells. In conclusion, SPHs-3 could protect cells against Pb 2+ -induced cytotoxicity, suggesting that Se-enriched rice may be a feasible candidate to improve health standard of the Pb 2+ -pollution population.
研究领域:
毒理学
·
细胞生物学
·
营养科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TALANTA
·
2022
·
IF 6.556
Shan He,Wen-Le Fang,Xiao-Feng Guo,Hong Wang
Redox homeostasis is the guarantee for the normal operation of living organisms. Given its importance, monitoring dynamic changes of redox state will facilitate the study of relevant physiological and pathological processes. Herein, a two-photon fluorescent probe NA-Se with selenomorpholine as the response site has been developed for reversible detection of redox state. NA-Se exhibits outstanding analytical performance, including a rapid response to ClO − within 8 s, a detection limit as low as 13.3 nM, and at least 10 redox reversible cycles. Furthermore, NA-Se has improved water solubility and extremely low cytotoxicity, making it ideal for bioimaging. Finally, NA-Se has been successfully applied to monitor the ClO − /GSH redox cycle in living cells and zebrafish. This work may provide an effective tool for studying redox state and related diseases in vivo.
研究领域:
生物化学
·
医学影像
·
细胞生物学
✓ 已验证
产品关联
DOI
高影响因子
INORGANIC CHEMISTRY
·
2021
·
IF 5.165
Zhi-Hui Shi,Mei Yang,Wen-Dong Yao,Wenlong Liu,Sheng-Ping Guo
Two chalcogenophosphates, SnPS2.86Se0.14 (1) and SnPSe3 (2), are isostructural and crystallize in the monoclinic noncentrosymmetric space group Pn. Their three-dimensional (3D) structures are constructed by [Sn(1)Q8] hendecahedra and [Sn(2)Q8] dodecahedra by sharing Q vertices and edges, leaving cavities for isolated [P2Q6] (Q = S/Se, Se) dimers. A second-harmonic-generation (SHG) measurement indicates that 1 is phase-matchable with a response of approximately 1.2 × AgGaS2 (AGS), which is verified by the theoretical calculation result. The powder sample of 1 exhibits a high laser-induced damage threshold of 3.9 × AGS. For comparison, the known SnPS3 (3) was also synthesized and evaluated using the same method. The chemical composition–NLO performance relationship of 1–3 is also discussed. Dipole moment calculation results suggest that [SnQ8] polyhedra make the main contribution to their excellent nonlinear optical (NLO) performance.
研究领域:
材料科学
·
非线性光学
·
晶体学
✓ 已验证
DOI
高影响因子
Nanoscale Research Letters
·
2015
·Vol. 10
·期 1
·1-6
·
IF 2.779
Guo Jing,Pei Yingli,Zhou Zhengji,Zhou Wenhui,Kou Dongxing,Wu Sixin
Solution-processed approach for the deposition of Cu 2 ZnSn (S,Se) 4 (CZTSSe) absorbing layer offers a route for fabricating thin film solar cell that is appealing because of simplified and low-cost manufacturing, large-area coverage, and better compatibility with flexible substrates. In this work, we present a simple solution-based approach for simultaneously dissolving the low-cost elemental Cu, Zn, Sn, S, and Se powder, forming a homogeneous CZTSSe precursor solution in a short time. Dense and compact kesterite CZTSSe thin film with high crystallinity and uniform composition was obtained by selenizing the low-temperature annealed spin-coated precursor film. Standard CZTSSe thin film solar cell based on the selenized CZTSSe thin film was fabricated and an efficiency of 6.4 % was achieved.
研究领域:
材料科学
·
能源技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2021
·
IF 5.316
Lanwei Li,Chengxiao Peng,Jing Chen,Zheng Ma,Yanqun Chen,Shuyao Li,Jianli Wang,Chao Wang
Phase transition will lead to abrupt change of thermoelectric material’s properties, which will have a negative influence on the application of thermoelectric device. Therefore, avoiding the phase transition of Ag 2 S is particularly important for its heat collection applications. In this work, we reported, for the first time, that Cu-Se co-alloying in Ag 2 S can suppress phase transition and improve thermoelectric properties. Specifically, different elements and compounds alloying in Ag 2 S samples were prepared, and their influences on the phase change behavior and thermoelectric performance stability of Ag 2 S are systematically studied. It is found that the free enthalpy decreases and the heat absorption peak disappears for the Cu-Se co-alloyed Ag 2 S sample. In addition, the average lattice thermal conductivity is greatly reduced, and the κ L of Ag 1.8 Cu 0.2 S 0.5 Se 0.5 is around 0.27 W m −1 K −1 from 330 K to 450 K. Therefore, a high ZT is obtained for Cu-Se co-alloyed Ag 2 S.
研究领域:
材料科学
·
凝聚态物理
·
热电材料
·
无机非金属材料
·
功能材料
✓ 已验证
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2020
·
IF 7.489
Miaomiao Yu,Feng Gao,Yunxia Hu,Lifeng Wang,PingAn Hu,Wei Feng
Multilayer indium selenide (InSe) is a good candidate for high performance electronic and optoelectronic devices. The electrical performance of InSe is effectively regulated by dielectric layers, contact electrodes and surface doping. However, as a powerful tool to tune properties of materials, alloy engineering is absent for multilayer InSe. In this letter, for the first time, we investigate the electrical property of InSe 1-x Te x alloys and optoelectronic property of InSe-InSe 0.82 Te 0.18 p-n heterojunction. The electrical transport properties of InSe 1-x Te x alloys strongly depend on the content of Te composition. With the ratio of Te/Se increasing, the n -type electron transport behavior of InSe gradually transfers to the p-type hole transport behavior of InSe 0.82 Te 0.18 . The p-n InSe-InSe 0.82 Te 0.18 heterojunction shows a rectification effect and a self-powered photodetection. The self-powered photodetector (SPPD) has a broad photodetection range from visible light (400 nm) to near-infrared (NIR) light (1000 nm). The responsivity ( R ) of SPPD is 14.1 mA/W under illuminated by NIR light (900 nm) at zero bias, which is comparable to some of the 2D heterojunctions NIR photodetectors measured with an external bias. The SPPD also shows a stable and fast response to NIR light (900 nm). This work demonstrates that the electrical transport properties of InSe 1-x Te x alloys significantly rely on the ratio of Te/Se and suggests that InSe-InSe 1-x Te x p-n heterojunction has a excellent potential for application in the self-powered optoelectronic device.
研究领域:
材料科学
·
电子工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CELL PROLIFERATION
·
2021
·Vol. 54
·期 5
·e13038
·
IF 6.831
Jia Ma,Jing Huang,Jinli Sun,Yanfeng Zhou,Xiaoyuan Ji,Daoxia Guo,Chang Liu,Jiyu Li,Jiye Zhang,Haiyun Song
Objectives Organic Selenium (Se) compounds such as L-Se-methylselenocysteine (L-SeMC/SeMC) have been employed as a class of anti-oxidant to protect normal tissues and organs from chemotherapy-induced systemic toxicity. However, their comprehensive effects on cancer cell proliferation and tumour progression remain elusive. Materials and Methods CCK-8 assays were conducted to determine the viabilities of cancer cells after exposure to SeMC, chemotherapeutics or combined treatment. Intracellular reactive oxygen species (ROS) levels and lipid peroxidation levels were assessed via fluorescence staining. The efficacy of free drugs or drug-loaded hydrogel against tumour growth was evaluated in a xenograft mouse model. Results Among tested cancer cells and normal cells, the A549 lung adenocarcinoma cells showed higher sensitivity to SeMC exposure. In addition, combined treatments with several types of chemotherapeutics induced synergistic lethality. SeMC promoted lipid peroxidation in A549 cells and thereby increased ROS generation. Significantly, the in vivo efficacy of combination therapy was largely potentiated by hydrogel-mediate drug delivery. Conclusions Our study reveals the selectivity of SeMC in the inhibition of cancer cell proliferation and develops an efficient strategy for local combination therapy.
研究领域:
肿瘤学
·
药理学
·
分子生物学
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）