NEW JOURNAL OF CHEMISTRY
·
2023
·Vol. 47
·期 43
·20157-20170
·
IF 3.3
Xiaojun Dai,Yan Cheng,Tingting Liu,Lingjuan Mao,Ruihua Kang,Qiang Wei,Yasong Zhou
In the process of petroleum refining, realizing the production and utilization of chemical raw materials is the common goal pursued by the petrochemical industry at present. The integration of the refining and chemical industry can not only produce clean fuel, but also meet the demand of the chemical industry for raw materials. In this study, Y zeolites with controllable crystal size and particle size were successfully prepared by simply adjusting the composition of the directing agent. Through a series of characterization, the effects of the composition change of the directing agent on the physicochemical properties of Y zeolites were investigated. Corresponding NiWS supported catalysts were prepared by using synthesized Y zeolites as supports. Taking naphthalene as the model reactant, the effects of crystal size and particle size of Y zeolites on the catalytic performance of the catalyst and on the hydrocracking of naphthalene to C6–C8 products were investigated. The results show that the preparation of small crystal Y zeolites can be realized by simply adjusting the composition of the directing agent, and the corresponding catalyst can realize the efficient production of chemical raw materials. This is expected to provide a simple, economical, feasible, and effective idea for the petrochemical industry to realize the goal of refining and chemical integration.
研究领域:
石油化学工程
·
催化材料科学
✓ 已验证
DOI
高影响因子
FUEL
·
2025
·
IF 7.5
Fan Shao,Fengzhi Guo,Tianyu Bai,Zhen Xu,Han Yang,Wenbo Kang,Yasong Zhou,Wenbin Huang,Gang Wang,Qiang Wei
The inherent diffusion constraints imposed by narrow micropores and elongated channels in Y zeolites severely limit jet fuel selectivity during Fischer-Tropsch wax hydrocracking. Advanced supports were synthesized via seed-directed crystallization (nano-Y-0P zeolite) and PDDA (polydiallydimethyl ammonium chloride)-mediated assembly (hierarchical nano-Y-xP zeolites, x = 0.1, 0.3, 0.6, 0.9). This dual-strategy synergistically addresses diffusion constraints in conventional Y-zeolite by optimizing nano structure of active sites and improving interfacial mass transfer (i.e., nano-crystal size and hierarchical porosity). Intelligent Gravimetric Analysis (IGA) directly validates hierarchical porosity and nanocrystalline advantages. Y-0.6P zeolite with optimal mesoporosity (0.75 cm 3 /g vs. 0.25 cm 3 /g in conventional Y-zeolite) and minimal crystallite size (131 nm vs. 1258 nm in conventional Y-zeolite) achieves intrinsic diffusion enhancement—the 5.36-fold higher diffusion rate than conventional S-Y zeolite. Zeolite crystallite size and hierarchical porosity critically govern metal–acid functionality balance by modulating acid site density (589.7 μmol/g vs. 812.4 μmol/g in conventional Y zeolite) and optimizing metal dispersion (40.5 %, vs. 18.26 % in conventional Y-zeolite). Pt/(Y-0.6P+ASA) catalyst achieves peak performance with 35.04 % C 9 –C 17 yield and 47.35 % selectivity in n-docosane hydrocracking. Notably, Fischer-Tropsch wax hydrocracking yields 26.83 % jet fuel (49.88 % selectivity) with ideal bell-shaped distribution. This work demonstrates Y-0.6P-supported catalyst has industrial potential for aviation fuel production from Fischer-Tropsch wax upgrading.
研究领域:
催化化学
·
能源化工
·
材料科学
·
石油炼制
·
绿色能源
✓ 已验证
DOI
高影响因子
CORROSION SCIENCE
·
2024
·
IF 7.4
Keda Xiao,Yi Zeng,Xiang Xiong,Jinrun Hu,Shiyan Chen,Tianyou Li
Si-B-Mo-Y modified SiC/SiC composites were prepared by reactive melt infiltration (RMI) process to study their high-temperature water-oxygen corrosion resistance, and to compare them with SiC/SiC composites prepared by RMI using Si. The results show that the corrosion rates of the modified composites are only 1/9, 1/10 and 1/3 of those of the comparison samples at 1200°C, 1300°C and 1400°C, respectively, which is attributed to the higher densification of the modified composites. More importantly, the modified composites were able to form borosilicates, which effectively healed the oxide film defects; meanwhile, yttrium silicate inhibited the reaction between borosilicates and water vapor.
研究领域:
材料科学
·
腐蚀与防护
✓ 已验证
产品关联
DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2014
·
IF 6.451
Huanshun Yin,Xinxu Wang,Yunlong Guo,Yunlei Zhou,Shiyun Ai
An effective assay method for monitoring protein kinase activity and screening inhibitors is greatly beneficial to kinase-related drug discovery, early diagnosis of diseases, and therapeutic effect evaluation. Herein, we develop a simple electrochemical method for detecting the activity of casein kinase II (CK2) based on phosphorylation against carboxypeptidase Y (CPY) digestion triggered signal amplification , where CK2 catalyzed phosphorylation event protects the substrate peptide from the digestion of CPY, maintains the repulsive force of the substrate peptide towards the redox probe, and results in a weak electrochemical signal. Whereas, without phosphorylation, the substrate peptide is digested by CPY and a strong electrochemical signal is obtained. The detection feasibility is demonstrated for the assay of CK2 activity with low detection limit of 0.047 unit/mL. Moreover, the biosensor was used for the analysis of kinase inhibition. Based on the electrochemical signal dependent inhibitor concentration, the IC 50 value of ellagic acid was estimated to be 39.77 nM. The proposed method is also successfully applied to analyze CK2 activity in cell lysates, proving the applicability in complex biological samples.
研究领域:
生物化学
·
分析化学
·
药物发现
·
疾病诊断
✓ 已验证
DOI
PubMed
高影响因子
MICROPOROUS AND MESOPOROUS MATERIALS
·
2021
·
IF 5.455
Pusheng Liu,Ying Cui,Jianyu Wang,Xiaohui Du,Haitao Zhang,Adrian Humphries,Mingjun Jia,Jihong Yu
Rare earth (RE)-exchanged zeolite Y is the major active component of fluid catalytic cracking (FCC) catalysts. Herein, a series of yttrium (Y 3+ )-exchanged zeolites Y was prepared by the ion-exchange method, and the location of Y 3+ ions in the Y 3+ -exchange zeolite NaY was determined by fitting synchrotron radiation X-ray powder diffraction (XRPD) pattern combined with the infrared spectra in the hydroxyl stretching region. In analogy to lanthanum (La 3+ )-exchanged zeolite Y, Y 3+ ions were preferentially located inside the sodalite units near the double six-membered rings (D6R's), octahedrally coordinating to three framework oxygens and to three H 2 O molecules (or OH groups) in close proximity. The substitution of Y 3+ ions for counter-ions Na + caused a noticeable shrinkage of the unit cell due mainly to the relatively small ionic radius and high charge density of Y 3+ ions. As a consequence, the Y 3+ -exchanged HY-based FCC catalyst exhibited improved steam stability, and higher selectivity for high-value products (liquefied petroleum gas and C 5 +gasoline) in n-docosane cracking compared with the La 3+ -exchanged HY-based catalyst.
研究领域:
化学工程
·
催化材料科学
✓ 已验证
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2022
·
IF 5.304
Bohong Li,Meiyu Wang,Jingjin Zhao
Ascorbic acid (AA) which can be supplemented by exogenous sources such as food and beverage, plays an important role in human health. Abnormal level of AA in human body usually leads to various diseases. A facile MnO 2 nanosheet-assisted ratiometric fluorescent sensor for AA was constructed in this work. MnO 2 nanosheet (MnO 2 NS) could not only greatly quench the fluorescence of Pyronin Y (PY) by inner filter effect (IFE) but also oxidize non-fluorescent thiamine (vitamin B 1 , VB 1 ) to blue fluorescent thiochrome (oxVB 1 ) by taking advantage of the oxidase-mimicking activity simultaneously. However, MnO 2 NS could be reduced to Mn 2+ in the presence of AA, inhibiting the IFE and oxidase-mimicking activity. According to this principle, the fluorescence intensity of oxVB 1 decreasing at 440 nm and the fluorescence of PY recovering at 560 nm. Under optimal conditions, the MnO 2 NS-PY-VB 1 system showed a wide linear range towards AA in the range of 0.25–110 µM with a low detection limit reaching 0.1 µM. Furthermore, it was also applied for sensitive detection of AA in orange juice and human serum.
研究领域:
分析化学
·
生物化学
·
传感器与执行器
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2019
·
IF 6.393
Jiaojiao Zhou,Wenjing Wang,Shuojun Li,Axiu Nie,Zhiyong Song,Mohamed F. Foda,Zhicheng Lu,Ling Zhao,Heyou Han
An innovative fluorescent and colorimetric dual-mode strategy based on Y-shaped DNA was proposed for the detection of rabies virus oligonucleotide. The cascade assembly of hairpin probes was initiated by the target, leading to the formation of Y-shaped DNA accompanied by freeing target to catalyze the next assembly process. The fluorescence recovery of the fluorophore FAM was accompanied by opening of hairpin probe. A colorimetric signal was generated by the proximity of glucose oxidase (GOx) and horseradish peroxidase (HRP), which was reflected by enhanced catalytic capability to TMB. Using this method, target DNA can be detected with a wide linear range from 0.1 to 6 nM with a detection limit of 15 pM, and from 0.5 to 60 nM with a detection limit of 60 pM for fluorescent and colorimetric readout, respectively. Moreover, the dual-mode detection strategy exhibited excellent selectivity towards the target compared with interference oligonucleotides. In addition, recoveries ranging from 96.0% to 106% with RSD values varying from 3.2% to 5.4%, and from 91.0% to 102% with RSD values varying from 3.3% to 7.1% for fluorescent and colorimetric studies, respectively, were obtained in diluted cerebrospinal fluid samples. The proposed dual-mode sensor is easy to operate with excellent detection performance. It would be superior to single mode detection and more practicable for quantitative detection of nucleic acid-related biomarkers due to the self-correction capability.
研究领域:
生物化学
·
分子生物学
·
分析化学
·
病毒学
✓ 已验证
产品关联
DOI
高影响因子
MATERIALS CHEMISTRY AND PHYSICS
·
2022
·
IF 4.778
Yuanming Gao,Yu Bai,Peng Zhang,Li Sun,Caiwen Liu,Hongying Dong,Qing Geng,Wei Wang,Wen Ma
In this study, the Yb–Y co-doped SrZrO 3 (SZ) coatings [SZYY-1 (Sr 1.0 (Zr 0.9 Yb 0.05 Y 0.05 )O 2.95 ), SZYY-2 (Sr 0.9 (Zr 0.9 Yb 0.05 Y 0.05 )O 2.85 ), and SZYY-3 (Sr 0.8 (Zr 0.9 Yb 0.05 Y 0.05 )O 2.75 )] were deposited by SPS (Suspension plasma spray) using the corresponding co-precipitation prepared precursors suspension. In the three as-sprayed SZYY coatings, there were some typical suspension plasma-sprayed coating structures, such as columnar crystals, vertical cracks, and micro/nanopores. The TCs (Thermal conductivities) of the three as-sprayed SZYY coatings were 1.23–1.88, 0.80–1.41, and 0.88–1.43 W/(m · K) at 100–1400 °C, respectively, which were at least 19% lower than that of the SZ coating (1.25 W/(m · K), 1000 °C). The TECs (Thermal expansion coefficients) of the three as-sprayed SZYY coatings were (7.8–8.7) × 10 −6 , (8.0–9.8) × 10 −6 , and (8.1–9.8) × 10 −6 /K, respectively (200–1360 °C). The sintering coefficients of the three as-sprayed SZYY coatings were 5.69 × 10 −6 , 4.29 × 10 −6 , and 3.84 × 10 −6 /s, respectively. The SZYY-3 coating showed the best SR (Sintering resistance), followed by the SZYY-2 coating and SZYY-1 coating. The SPS SZYY-2 coating with good phase stability, low TC (Thermal conductivity) and good SR is a promising new TBCs (Thermal barrier coatings) material. It is expected to be an alternative TBCs material for the next generation of high performance gas turbines .
研究领域:
材料科学
·
热物理
·
涂层技术
·
能源工程
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2022
·
IF 5.304
Lina Wang,Xiangbiao Zeng,Li Zhang,Ying Yu,Bixia Lin,Yumin Wang,Manli Guo,Yujuan Cao
Herein, a novel filed-free electrochemical sensor based on inverted Y-type DNA conformation was developed for the ultrasensitive determination of tetracycline (TC). In this sensor, a ferrocene was immobilized on a DNA strand near the interface and showing a signal as reference. Meanwhile, a methylene blue (MB) was modified on a DNA vertical away from the interface, presenting a little signal. When the target TC attracted the aptamer, the DNA modifying MB was released, and then exchanged another DNA near the interface via toe-hold strand displacement effect. This caused an obvious enhancement of the MB signal, and achieved a sensitive response to the TC amount. In comparison to other DNA sensors based on field-confined assembling mode, this sensor exploited the transform of self-structure to make signal response, which avoids the steric hinerance effect and achieving field-free conversion. Meanwhile, the immobile ferrocene provided a reference proportion, reducing the influence of nonspecific signal on measurement accuracy. The followed assays demonstrated when the base-pairs on the straight side were 1.5-fold to that on the hypotenuse, the strand transferring efficiency and signal response were optimal. It exhibited a linearity of 1.0 × 10 -1 –1.0 × 10 3 nM for TC with a detection limit of 28.4 pM. In practical assay, the measured result was matched to that of the contrast method. Meanwhile, the recovery rates ranged from 98.0% to 103.0% with the RSD of 1.4%∼2.5%, respectively. Indicating an expectant application prospect of the proposed sensor in antibiotic monitoring.
研究领域:
生物化学
·
分析化学
·
环境监测
✓ 已验证
产品关联
DOI
高影响因子
Materials Science & Engineering C-Materials for Biological Applications
·
2017
·
IF 4.164
Peizong Deng,Fangfang Teng,Feilong Zhou,Zhimei Song,Ning Meng,Na Liu,Runliang Feng
Ketoconazole is a hydrophobic broad-spectrum antifungal agent for skin infection therapy. In order to develop topical formulation of ketoconazole for improving its selective skin deposition and water-solubility, ketoconazole-loaded Y-shaped monomethoxy poly(ethylene glycol)-block-poly(ɛ-caprolactone) micelles were prepared through thin-film hydration method with high entrapment efficiency (96.1 ± 0.76%) and small particle (about 58.66 nm). The drug-loaded micelles showed comparative in vitro antimicrobial activity with KET cream. In e x in vivo skin deposition and permeation study, ketoconazole-loaded micelles provided skin accumulation higher than marketed ketoconazole cream without obvious permeation in the whole period. Fluorescence microscopy study and histopathological study demonstrated the copolymeric micelles' penetrating into skin in depth due to its capability of weakening the barrier function of stratum corneum. In vivo skin deposition parameters further confirmed high skin deposition of drug-loaded micelles (AUC (0-t) = 396.16 μg·h/cm 2 ) over marketed ketoconazole cream (AUC (0-t) = 250.03 μg·h/cm 2 ). Meanwhile, in vivo pharmacokinetic parameters proved that ketoconazole-loaded micelles reduced ketoconazole's distribution in blood in comparison with the cream (AUC (0-t) = 93,028.00 μg·h/L vs AUC (0-t) = 151,714.00 μg·h/L), meaning lower possibility of its systemic unwanted effects in the skin fungal infection treatment. The results suggested that the copolymeric micelles can be adopted for specific delivering ketoconazole into skin for fungal infection cure.
研究领域:
药剂学
·
皮肤病学
·
生物材料学
✓ 已验证
DOI
PubMed
高影响因子
SYNLETT
·
2023
·
IF 2
Shengyu Yu,Jiahao Liu,Zhe Wang,Terumasa Kato,Yan Liu,Keiji Maruoka
A series of soluble Y-shaped trimers of chiral phase-transfer catalysts were synthesized and utilized in the asymmetric alkylation of amino acid Schiff bases. The length of the linker between the ammonium cation of the simplified Maruoka catalyst and a phloroglucinol moiety was varied and excellent yields and enantioselectivity were observed when using the Y-shaped trimer of chiral phase-transfer catalyst with an octamethylene linker. A theoretical study of the most efficient Y-shaped trimer of chiral phase-transfer catalyst suggests the chiral ammonium center of the catalyst is more exposed and thus more available in the reaction.
研究领域:
有机化学
·
催化化学
✓ 已验证
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2020
·Vol. 45
·期 2
·705-713
·
IF 3.288
Samuthirarajan Senthilkumar,Wei Zhong,Mookan Natarajan,Chunxin Lu,Binyu Xu,Xiaoming Liu
An efficient and green protocol for aerobic oxidation of benzylic alcohols in ethanol using CuI–Y zeolite catalysts assisted by TEMPO (TEMPO = 2,2,6,6-tetramethyl-1-piperidine-N-oxyl) as the radical co-catalyst in the presence of atmospheric air under mild conditions is reported. The CuI–Y zeolite prepared via ion exchange between CuCl and HY zeolite was fully characterized by a variety of spectroscopic techniques including XRD, XPS, SEM, EDX and HRTEM. The incorporation of Cu(I) into the 3D-framework of the zeolite rendered the catalyst with good durability. The results of repetitive runs revealed that in the first three runs, there was hardly a decline in activity and a more substantial decrease in yield was observed afterwards, while the selectivity remained almost unchanged. The loss in activity was attributed to both the formation of CuO and the bleaching of copper into the liquid phase during the catalysis, of which the formation of CuO was believed to be the major contributor since the bleaching loss for each run was negligible (<2%). In this catalytic system, except TEMPO, no other additives were needed, either a base or a ligand, which was essential in some reported catalytic systems for the oxidation of alcohols. The aerobic oxidation proceeded under mild conditions (60 °C, and 18 hours) to quantitatively and selectively convert a wide range of benzylic alcohols to corresponding aldehydes, which shows great potential in developing green and environmentally benign catalysts for aerobic oxidation of alcohols. The system demonstrated excellent tolerance against electron-withdrawing groups on the phenyl ring of the alcohols and showed sensitivity to steric hindrance of the substrates, which is due to the confinement of the pores of the zeolite in which the oxidation occurred. Based on the mechanism reported in the literature for homogenous oxidation, a mechanism was analogously proposed for the aerobic oxidation of benzylic alcohols catalysed by this Cu(I)-containing zeolite catalyst.
研究领域:
化学
·
催化
·
绿色化学
·
材料科学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）