JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
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2017
·Vol. 85
·期 2
·470-479
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IF 1.575
Gao Fei,Sheng Ye,Song Yanhua,Zou Haifeng
Abstract Silica composited flower-like microspheres were synthesized by a facile sol–gel synthesis method using trivalent europium tartrate (Eu 3+ -TTA) as the template. Fourier transform infrared spectra (FT-IR) X-ray photoelectron spectroscopy (XPS), X-ray diffraction analyses (XRD), Energy-dispersive X-ray (EDS) spectroscopy, scanning electron microscopy (SEM), thermogravimetry-differential thermal analysis (TG-DTA) were employed to characterize the composition, structure, and morphology of the products. The microspheres were composed of nanosheets as petals. Size of the spherical shape varied with the amount of tetraethoxysilane (TEOS) addition. As the addition of TEOS decreased the diameters of microspheres increased, and it was proven that Eu 3+ ions existed in the form of Si–O–Eu covalent bond. Furthermore, a sol–gel templated mechanism is proposed to interpret the formation process of flower-like microspheres shape. The hollow-liked microspheres were obtained by a following calcination process. In addition, photoluminescent emission of the products was further discussed, which indicated that Eu 3+ ions exhibit characteristic luminescent emissions and their luminescent intensity after calcination is higher than that of as-synthesized sample. Graphical abstract The silica composited microspheres with flower-like shape were prepared successfully by a facile sol–gel synthesis method using trivalent europium tartrate (Eu 3+ -TTA) as a template. A sol–gel templated mechanism was proposed to interpret the formation process of flower-like shape microspheres. During this process, Eu 3+ -tartrate was supposed to form supramolecular template by self-assembly and coordinate with silica oligomer by means of intermolecular interactions. Furthermore, it was indicated that Eu 3+ exhibits strong characteristic luminescence in this system.
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ANALYTICAL CHEMISTRY
·
2025
·
IF 6.7
Shuying Li,Zhengang Han,Zhilan Wang,Yanjun Feng,Yubao Lan,Yaqi Zhao,Yuling Gao,Kainan Kang,Peiyao Du,Xiaoquan Lu
For optimal energy transfer in self-luminous lanthanide metal–organic frameworks (Ln-MOFs), the energy of the lowest triplet excited state must align with ideal energy levels. Failure to meet this condition can lead to reverse energy transfer, reducing luminous efficiency. In this study, we developed a mixed-ligand MOF, Eu-TCPP-BOP, which exists as an ECL self-enhancing luminophore. We used SPECM to study the role of boron ligands as a bridge for electron transport in improving the ECL performance of Eu-TCPP. The ligands H4TCPP and 5-BOP act as electron donor and shuttle, facilitating electron transport during the synthesis of Eu-TCPP-BOP and promoting energy transfer to the excited state of the acceptor Ln3+, thus enhancing overall energy transfer in Ln-MOF. The results indicate that the introduction of boron ligands enhances the ECL intensity of Eu-TCPP by a factor of 1.4 under voltage excitation. As an ECL sensing platform, it demonstrates high sensitivity and selectivity for the detection of catechol, with a concentration range of 1∼70 μM and a detection limit of 0.35 μM.
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-9
·
IF 15.7
Niu Xinyi,Li Yang,Lu Haolin,Wang Zhaoyu,Zhang Yunxin,Shao Tianyin,Wang Hebin,Gull Sehrish,Sun Bing,Zhang Hao-Li,Chen Yongsheng,Wang Kai,Du Yaping,Long Guankui
Chiral organic-inorganic hybrid metal halides as promising circularly polarized luminescence (CPL) emitter candidates hold great potential for high-definition displays and future spin-optoelectronics. The recent challenge lies primarily in developing high-performance red CPL emitters. Here, coupling the f - f transition characteristics of trivalent europium ions (Eu 3+ ) with chirality, we construct the chiral Eu-based halides, ( R / S -3BrMBA) 3 EuCl 6 , which exhibit strong and predictable red emission with large photoluminescence quantum yield (59.8%), narrow bandwidth (≈2 nm), long lifetime (≈2 ms), together with large dissymmetry factor | g lum | of 1.84 × 10 −2 . Compared with the previously reported chiral metal halides, these chiral Eu-based halides show the highest red CPL brightness. Furthermore, the degree of photoluminescence polarization in ( R / S -3BrMBA) 3 EuCl 6 can be manipulated by the external magnetic field. Particularly, benefiting from the field-generated Zeeman splitting and spin mixing at exciton states, an anomalously positive magneto-photoluminescence was observed at room temperature. This work provides an efficient strategy for constructing both high-performance and pure-red CPL emitters. It also opens the door for chiral rare-earth halides toward chiral optoelectronic and spintronic applications.
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Journal of Materials Chemistry C
·
2017
·Vol. 5
·期 7
·1685-1691
·
IF 5.256
Rui Zhou,Qi Zhao,Kai-Kai Liu,Ying-Jie Lu,Lin Dong,Chong-Xin Shan
A hybrid nanostructure based on ZnO quantum dots (QDs) has been fabricated for ratiometric detection of Bacillus anthracis spores, where yellow-emitting ZnO QDs are employed as the internal reference and europium ions (Eu3+) are chelated on the surface of the ZnO QDs as the signal report unit. The Eu3+ exhibits enhanced red luminescence upon bonding with calcium dipicolinate (CaDPA), an important biomarker of Bacillus anthracis spores, while the fluorescence of the ZnO QDs will not be altered. Accordingly, increased CaDPA levels can lead to variation of the two fluorescence intensity ratios of the ZnO/Eu hybrid nanostructure. The time-dependent fluorescence response reveals that the reaction can be completed within 8 s, thus enabling the rapid detection of Bacillus anthracis spores. The detection limit for CaDPA is 3 nM, which is six orders of magnitude lower than an infectious dosage of Bacillus anthracis spores for human beings (60 μM). In addition, the sensor shows a remarkable selectivity for CaDPA over other aromatic ligands, amino acids and common cellular ions. The fast response speed as well as good sensitivity and selectivity means the ZnO/Eu nanostructure has great potential applications in clinical analysis.
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INORGANIC CHEMISTRY
·
2015
·
IF 4.762
Jingyan Sun,Bo Song,Zhiqiang Ye,Jingli Yuan
Singlet oxygen (1O2) plays a key role in the photodynamic therapy (PDT) technique of neoplastic diseases. In this work, by using a 9,10-dimethyl-2-anthryl-containing β-diketone, 1,1,1,2,2-pentafluoro-5-(9′,10′-dimethyl-2′-anthryl)-3,5-pentanedione (Hpfdap), as a 1O2-recognition ligand, a novel β-diketonate–europium(III) complex that can act as a luminescence probe for 1O2, [Eu(pfdap)3(tpy)] (tpy = 2,2′,2″-terpyridine), has been designed and synthesized for the time-gated luminescence detection of 1O2 in living cells. The complex is weakly luminescent due to the quenching effect of 9,10-dimethyl-2-anthryl groups. After reaction with 1O2, accompanied by the formation of endoperoxides of 9,10-dimethyl-2-anthryl groups, the luminescence quenching disappears, so that the long-lived luminescence of the europium(III) complex is switched on. The complex showed highly selective luminescence response to 1O2 with a remarkable luminescence enhancement. Combined with the time-gated luminescence imaging technique, the complex was successfully used as a luminescent probe for the monitoring of the time-dependent generation of 1O2 in 5-aminolevulinic acid (a PDT drug) loaded HepG2 cells during the photodynamic process. In addition, by coloading the complex and a mitochondrial indicator, Mito-Tracker Green, into HepG2 cells, the specific localization of [Eu(pfdap)3(tpy)] molecules in mitochondria of HepG2 cells was demonstrated by confocal fluorescence imaging measurements.
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Talanta Open
·
2024
·
IF 4.1
Chen-Xi Zhao,Xiao-Xia Li,Yang Shu
Abnormal alkaline phosphatase levels have been associated with several diseases, including tumor growth, diabetes, liver dysfunction and so on. Generally, the occurrence and prognosis of these diseases can be reflected by the serum alkaline phosphatase level. In this work, Eu/DBM@SiO 2 @SiO 2 is prepared to protect the internal Eu complex from the external environment by wrapping Eu/DBM inside the silica shell. Then, Eu/DBM@SiO 2 @SiO 2 /MnO 2 , a sensor consists of Eu/DBM@SiO 2 @SiO 2 and MnO 2 , is prepared and applied for alkaline phosphatase detection. MnO 2 is used as the response part of alkaline phosphatase, which can be degraded to Mn 2+ by ascorbic acid. Ascorbic acid is the hydrolysate of alkaline phosphatase. In the process of this reaction, UV–vis absorption of Eu/DBM@SiO 2 @SiO 2 /MnO 2 is reduced and fluorescence is turned on. Alkaline phosphatase concentration is linearly correlated with the logarithmic value of fluorescence enhancement in the range of 10.0–100.0 U/L with linear equation of Lg(F/F 0 )=0.008C-0.030 (R 2 =0.99). For fluorescence method, the LOQ is 10.0 U/L and the LOD is 4.4 U/L. For colorimetric method, the concentration of alkaline phosphatase is linearly correlated with the decrease of absorption intensity in the range of 20.0–90.0 U/L with the linear equation of A/A 0 =-0.012C+1.148 (R 2 =0.99). The LOQ is 20.0 U/L and the LOD is 7.2 U/L. The detection system has good selectivity and can detect alkaline phosphatase in human serum samples, the accuracy of the detection system is verified by the experiment of spike-in experiment. The RSD of alkaline phosphatase concentration in serum samples is in the range of 1.4–8.4 %. This method has potential application in the detection of ALP activity in biological samples.
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TALANTA
·
2024
·
IF 5.6
Chen-Xi Zhao,Xiao-Xia Li,Yang Shu
Alkaline phosphatase (ALP) is abnormally expressed in some cancers and promotes the growth, metastasis, and invasion of cancer cells. The detection of ALP is of great significance for both pathological study and clinical detection. In this work, a europium (Eu)-based fluorescence detection sensor was prepared in a mild reaction condition. LaF 3 :Eu nanoparticles was mixed with ethylene imine polymer (PEI) and Ag + ions. PEI was used as stabilizer and reducing agent, and Ag + ions were reduced as molecular-like silver clusters (ML-Ag NCs). The fluorescence of LaF 3 :Eu nanoparticles was enhanced by ML-Ag NCs through energy transfer. When ascorbic acid 2-phosphate (AAP) was hydrolyzed to ascorbic acid (AA) in the presence of ALP, AA reduced Ag + ions to silver nanoparticles (Ag NPs) and quenched the fluorescence of LaF 3 :Eu/PEI/Ag. The activity of ALP was detected by measuring the fluorescence intensity of Eu 3+ at 618 nm. In the concentration range from 2.0 to 16.0 U/L, the fluorescence intensity ratio ((F 0 –F)/F 0 ) had a linear relationship with the logarithm of ALP concentration. The limit of detection (LOD) was 1.3 U/L. Moreover, the ALP activity was detected successfully in cancer cells by this method. The sensing platform has application potential in the detection of ALP activity in biological systems.
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Journal of Materials Chemistry C
·
2024
·Vol. 12
·期 6
·2258-2264
·
IF 5.7
Gang Ren,Zhouyuanhang Wang,Yan Kuai,Zhigang Cao,Feng Xu,Yu Liu,Kang Xie,Siqi Li,Benli Yu,Zhijia Hu
Scintillating fibers have been widely used in medical diagnostics, high-energy physics, and industrial inspection. However, the fabrication of scintillating fibers with excellent radiation stability and high luminescence remains a major challenge. Here, we report a new plastic scintillation fiber with Eu (TTA)3(TPPO)2 as the core scintillator (Eu-PSF). The Eu-PSF can avoid the self-absorption phenomenon and has a high light yield of 9000 photons per MeV. The luminescence of Eu-PSF decreases by only about 5% after one hour of X-ray exposure at 0.555 μGy s−1 and 8.325 μGy s−1. Attractively, Eu-PSF has an excellent linear relationship with X-ray dose, with a detection limit of 555 nGy s−1, well below the standard dose for X-ray diagnosis (5.5 μGy s−1). This suggests that Eu-PSF can be used to detect low doses of radiation, particularly in medical diagnosis. In addition, we have conducted X-ray imaging studies using Eu-PSF fiber arrays, demonstrating the feasibility of Eu-PSF for X-ray imaging. Due to the good light conductivity of optical fibers, Eu-PSF has great potential for radiation detection over long distances.
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ACS Applied Nano Materials
·
2024
·
IF 5.3
Yali Qiao,Yujing Han,Jinfang Shan
Rapid and sensitive detection of tetracyclines (TCs) is an urgent requirement for effective food safety control and human health protection. Herein, we presented an approach utilizing europium (III−functionalized fluorescent polyethylenimine-based nonconjugated polymer nanodots (PEI-PDs-Eu3+) for ratiometric and signal-amplified sensing of TCs. The PEI-PDs-Eu3+ were synthesized via a simple one-pot one-step reaction of PEI, Eu3+, and l-ascorbic acid (AA). PEI-PDs not only served as a reference signal but also as nanocarriers chelating response signal Eu3+ on matrix of nanodots. The Eu3+ doping could lead to the increase in size of nanodots. In this protocol, the red fluorescence of the Eu3+ complex could be effectively enhanced by TCs through the antenna effect (AE), while the blue fluorescence of PEI-PDs almost remained. The PEI-PDs-Eu3+−based nanoprobe exhibited good detection limits as low as 5.6, 5.9, and 10.8 nM for tetracycline (TET), oxytetracycline (OXY), and doxycycline (DOX), respectively. The high sensitivity was attributed to the dense chelation of the Eu3+ complex on the nanomatrix of PEI-PDs endowing the PEI-PDs-Eu3+−based nanoprobe realization of a signal amplification effect for sensing of TCs. The application of the assay platform for the detection of TET in milk samples was demonstrated. Accordingly, the as-developed nanoprobe demonstrated the advantages of low cost, easy preparation, and desirable specificity and sensitivity.
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FOOD CHEMISTRY
·
2024
·
IF 8.5
Lin-Lin Zhang,Li Li,Dan Wang,Yanping Hong,Kaijie Tang,Jiaxin Hong,Zeng Chen,Wuying Yang,Limin Lu,Lu-Ying Duan
A facile, fast and visible sensing platform for ascorbic acid (AA) detection has been developed based on self-assembled hydrangea-like europium metal-organic framework (HL-EuMOF). HL-EuMOF was synthesized through a simple one-step mixing process with Eu 3+ and 1, 10-phenanthroline-2, 9-dicarboxylic acid at room temperature , which exhibited excellent properties including strong red fluorescence, long decay lifetime (548.623 μs) and good luminescent stability. Based on the specific redox reaction between Fe 3+ and AA, the HL-EuMOF@Fe 3+ was fabricated with “turn-off” response for AA, where the resulting Fe 2+ displayed effective fluorescence quenching ability toward HL-EuMOF. The sensor demonstrated low detection limit (31.94 nM), rapid response time (30 s) and high selectivity. Integration of smartphone-assisted RGB analysis with HL-EuMOF@Fe 3+ permitted convenient and visible quantitative determination of AA level. This approach also presented good detection performances in complex human serum and beverage samples, which could provide a valuable tool for AA detection in biomedical research and food industry.
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BIOSENSORS & BIOELECTRONICS
·
2021
·
IF 10.618
Qian Han,Cun Wang,Pingkun Liu,Gui Zhang,Li Song,Yingzi Fu
The excellent characteristics of porphyrins have inspired widespread interest in electrochemiluminescence (ECL). However, the limited ECL intensity and poor stability of porphyrins in aqueous solution are still severely restricted further biological application . Here, we subtly synthesized a functionalized europium and 5,10,15,20-tetrakis (4-carboxyphenyl) porphyrin (TCPP) coordination polymer (Eu-PCP) by a one-step solvothermal method . In sharp contrast to the pristine TCPP, Eu-PCP showed a higher and more stable ECL red-light emission (673 nm) at low potential (−1.1 V, vs Ag/AgCl), which was 7.7-fold higher ECL intensity and 4.6-fold efficiency. In view of the crucial role of mucin 1 (MUC1) in tumor overexpression , it was selected as the target molecule. Combined with exonuclease III (Exo III)-assisted recycling amplification strategy, a ternary ECL biosensor was constructed for the MUC1 detection based on Eu-PCP as a satisfied ECL emitter, gold nanoparticles capped CeO 2 (CeO 2 @Au) as the coreactant accelerator and peroxydisulfate as coreactant. Meanwhile, gold nanoparticles capped MnO 2 (MnO 2 @Au) was used as the quenching probe to achieve a highly sensitive detection of MUC1. The proposed biosensor exhibited a wide linear range from 1 fg mL −1 to 10 ng mL −1 with a low limit of detection (0.32 fg mL −1 ). By changing the corresponding target recognition DNA , this strategy could be expanded to detect other biomarkers.
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FOOD CHEMISTRY
·
2022
·
IF 9.231
Mi Yuan,Yu Jin,Long Yu,Yiming Bu,Mingtai Sun,Chao Yuan,Suhua Wang
Development of selective and sensitive methods for the detection of 2, 6-dipicolinic acid (DPA), a biomarker produced by bacterial spores, is of great significance for maintaining public health and food safety. Herein, a ratiometric fluorescence strategy using graphene carbon nitride (g-C 3 N 4 ) coupled with Eu 3+ is designed for the assay of DPA. As the concentration of DPA increases, the emission intensity of g-C 3 N 4 kept constant which acted as a stable internal reference, while the fluorescence of Eu 3+ was enhanced obviously due to the antenna effect. The linear calibration ranged from 0.1 to 15 μM with a detection limit of 13 nM was obtained. More Importantly, a paper-based sensor with a smartphone was successfully combined to perform colorimetric and visual detection of DPA in situ. This method has good performance for the detection of DPA, which is expected to broaden the application prospects of preliminary biomarker monitoring.
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