IEEE SENSORS JOURNAL
·
2024
·
IF 4.3
Cuixian Luo,Yimeng Dong,Yongjiao Sun,Yurong Huang,Lingrong Xue,Lifang Ren,Daming Wang,Minzhe Qin,Xinke Li
Tungsten disulfide (WS2) is emerging with dazzling visibility as a “layered material beyond graphene and molybdenum disulfide” due to its exquisite tunable electronic, surface structure, high carrier mobility, and physicochemical stability. In this article, In2O3 and Au nanoparticles (NPs) co-modified WS2 microsheets were prepared for detecting NO2 at room temperature (RT). The In2O3 and Au NPs were anchored on the surface of WS2 microsheets, which could be observed by the characterization. The NO2 sensing performance at RT was optimized by adjusting the contents of In2O3 and Au NPs. The proposed gas sensor based on Au1WIn6 (WS2 microsheets co-modified with 6 wt% In2O3 and 1 wt% Au NPs) showed the highest response (46.91 to 50 ppm NO2), limit of detection (LOD; 18.9 ppb), excellent linearity within the test range, and good stability under various relative humidity (RH), bending degrees, and bending times. The excellent result is attributed to the formation of a heterojunction, which increases the number of ionized oxygen adsorption sites and facilitates the reaction between NO2 gas and Au1WIn6. Therefore, it is believed that decorating WS2 microsheets with metal oxide and noble metal NPs is a promising strategy to improve the NO2 sensing property at RT.
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ANALYTICAL BIOCHEMISTRY
·
2024
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IF 2.6
Xiaoting Li,Xin Li,Jiayi Chen,Zuomin Tan,Chuan Wang
Bacteremia , as a serious infectious disease, has an increasing incidence and a high mortality rate . Early diagnosis and early treatment are crucial for improving the cure rate. In this work, we proposed an inductively coupled plasma mass spectrometry (ICP-MS)-based detection method combined with gold nanoparticle (Au NP) and silver nanoparticle (Ag NP) labeling for the simultaneous detection of Salmonella and Escherichia coli ( E. coli O157:H7) in human blood samples. Salmonella and E. coli O157:H7 were captured by magnetic beads coupled with anti-8G3 and anti-7C2, and then specifically labeled by Au NP-anti-5H12 and Ag NP-anti-8B1 respectively, which were used as signal probes for ICP-MS detection. Under the optimal experimental conditions, the limits of detection of 164 CFU mL −1 for Salmonella , 220 CFU mL −1 for E. coli O157:H7 and the linear ranges of 400–80,000 CFU mL −1 Salmonella , 400–60,000 CFU mL −1 E . coli O157:H7 were obtained. The proposed method can realize the simultaneous detection of two types of pathogenic bacteria in human whole blood in 3.5 h, showing great potential for the rapid diagnosis of bacteremia in clinic.
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ACS Applied Nano Materials
·
2024
·
IF 5.3
Mingchong Sui,Fangqing Wang,Caichi Liu,Qiuyan Hao,Ying Li,Hui Liu,Limin Liang
Cobalt–iron layered double hydroxide (CoFe LDH) is considered an advanced electrocatalyst toward the alkaline oxygen evolution reaction (OER), yet its poor stability is still a huge challenge. Here, based on an innovative spontaneous redox reaction (SRR) method, we synthesize a gold-nanoparticle-decorated CoFe LDH heterostructure on nickel foam (Au/CoFe LDH/NF) at room temperature. The heterostructure catalyst not only exhibits a low overpotential of 233 mV at 10 mA cm–2 but also displays 400 h stability without any degradation at ∼200 mA cm–2. The experimental and density functional theory (DFT) calculations validate that Au/CoFe LDH/NF with strong electronic coupling at the interface optimizes the electronic structure, reducing the OER energy barrier. In situ Raman spectra demonstrate that the transfer of electrons from Au nanoparticles to CoFe LDH alleviates the structural distortion of the catalyst during the OER, which is responsible for the strengthened stability.
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JOURNAL OF CHEMICAL PHYSICS
·
2024
·Vol. 161
·期 11
·
IF 3.1
Ran Xunan,Chen Zhihua,Ji Hongzhou,Ma Zhaoyu,Xie Yuxi,Li Wenping,Zhang Junying
With advantages such as low cost, high stability, and ease of production, visible light photocatalytic C 3 N 4 with a unique microscopic layered structure holds significant potential for development. However, its hydrogen production efficiency remains low due to the pronounced recombination of photo-generated charge carriers and limited surface reaction sites. Normally, the photocatalytic performance of C 3 N 4 can be enhanced by loading noble metals with surface plasmon resonance. It is worth noting that the size of noble metal nanoparticles has a great influence on photocatalytic performance. In this study, accurate controlling of the size and distribution of Au nanoparticles was achieved on the surface of C 3 N 4 by introducing amino groups to improve photocatalytic performance. Results show that uniformly distributed Au nanoparticles in the range of 2–6 nm can be obtained on C 3 N 4 with a remarkable enhancement of hydrogen production efficiency, which is about 114 times the property of pure C 3 N 4 . The small-sized and uniformly distributed Au nanoparticles can provide more reaction sites and increase the separation of photo-generated charge carriers, in turn improving Au/NH 3 –C 3 N 4 photocatalytic hydrogen release rate to 6.85 mmol g −1 h −1 . This work offers a facile way to enhance photocatalytic performance by controlling the size of metal nanoparticles on C 3 N 4 precisely.
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Materials
·
2025
·Vol. 18
·期 5
·969
·
IF 3.2
Shipeng Chen,Jinglan Xu,Dingchuan Huang,Weiwei Zhang,Tian Zhang,Liangliang Xiong,Xiaoqiang Fan
The Ni-Au coating with its inherent chemical stability is recognized as an effective method for boosting corrosion resistance in humid environments while preserving exceptional electrical conductivity. However, its anti-corrosion performance is affected by the structure characteristics of the coating due to the high corrosion potentials of Au and Ni. To enhance its protection properties, the deposition process parameters, including deposition time, deposition current density, and zincating times, were investigated. The morphology and structure of the coatings were characterized, while its anti-corrosion performance was assessed through electrochemical and accelerated salt-spray tests. Eventually, the elevated current density in the Ni-Au coating resulted in reduced grain size and improved surface morphology, ensuring superior anti-corrosion performance. Additionally, extending the Ni deposition time provided a second physical barrier for the dense and thick Ni layer to resist the invasion of corrosive media. Furthermore, grey theory was applied to predict the service life of the Ni-Au coating. This research provides valuable insights and constructive guidance for optimizing Ni-Au coating in various engineering applications.
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HYDROMETALLURGY
·
2024
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IF 4.8
Ronghao Liu,Jun Li,Xiaoxia Liu,Xiaolu Yin,Yanzhao Yang
The effective and environmentally friendly recovery of gold from secondary resources has recently received increased attention. Hydrophobic deep eutectic solvent (HDES) composed of N , N -di-butylacetamide and 1-decanoic acid was used to construct the liquid-liquid extraction system to extract Au(III) from HCl medium. At first, DSC, TGA, FT-IR, and 1 H NMR were used to describe the evidence of internal hydrogen bond interaction. The above evidence was verified in the molecular dynamics study of HDES. Then, a series of optimization experiments were carried out to investigate the extraction behaviors of HDES. Based on the results of optimization experiments, response surface method was used to explore the best experimental conditions and the results showed that HDES extracted 99% Au(III) under 0.56 mol/L HCl, 2.19 mol/L NaCl, and 5.83 mmol/L Au(III), and the maximum loading reached 77.0 mg/g. Further studies on the kinetics and thermodynamics of the extraction were used to propose an ion association mechanism. In addition, using 0.1 mol/L thiourea as the stripping agent, HDES displayed outstanding Au(III) selectivity and maintained the extraction efficiency in tests which involved 5-cycles. Overall, this study provides a green and efficient Au(III) recovery strategy for secondary resources.
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ACS Applied Nano Materials
·
2025
·
IF 5.5
Baichao Zhang,Lingwei Li,Ruiyuan Zhang,Yu Guo,Jixiang Fang
Promoting the efficiency of placing target molecules into hot spots and anchoring analytes onto the surface of plasmonic nanoparticles to maximize the enhancement effect and further improve the sensitivity of the surface-enhanced Raman spectroscopy (SERS) signal is an important challenge. Here, we report a molecular detection strategy via confined-enhanced Raman spectroscopy on a self-assembled Au nanoparticle (NP) film called solid substrate based confined-enhanced Raman spectroscopy (SS-CERS) to achieve highly sensitive and uniform molecular detection. The SS-CERS substrate was obtained by the interfacial self-assembly process of Au NPs, and then NaCl and AgNO3 were introduced to form a AgCl encapsulation shell on the Au NPs. The in situ packaged active shells formed on the surface of gold nanoparticles can significantly improve overall SERS properties. Importantly, compared with the traditional SERS substrate strategy, in which the limit of detection of crystal violet (CV) molecules is only 10–9 M, SS-CERS has an enhanced sensitivity of 10–12 M for CV molecules and excellent homogeneity with a RSD of about 5.63%. In addition, we applied the nanodetection strategy to the detection of Rhodamine 6G (R6G), Malachite green (MG) in fish, and carbendazim (CBZ) and other molecules in aquatic products, which showed excellent performance with clear Raman peaks obtained at 10–8 M or even lower concentrations. Therefore, this indicates its enormous potential for molecular detection in practical applications.
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MICROCHIMICA ACTA
·
2024
·Vol. 191
·期 11
·1-14
·
IF 5.3
Liu Yansheng,Sun Yukun,Jia Xiaobo,Zhou Jin,Li Kang,Li Zhaoxu,Wang Guofu
A method for detecting methamphetamine (MET), ketamine (KET), and morphine (MOP) molecules is presented using a reusable substrate based on SERS. The SERS substrate was prepared by etching the Au/Ag alloy film to synthesize a nanoporous Au membrane (AuNPM). By optimizing the preparation conditions and using rhodamine 6G (R6G) as an analyte, the AuNPM exhibited good SERS performance with a limit of detection (LOD) of 10 −9 mol L −1 . A competitive immunoassay category has been applied to the detection of MET, KET, and MOP. The MET, KET, and MOP antigens were functionalized on the surface of the AuNPM to specifically bind to the related drug antibodies. The Au nanoparticles (AuNPs) modified with 4-mercaptobenzoic acid (4-MBA) and antibodies against MET, KET, and MOP were used as nanotags. The 4-MBA served as the reporting molecule and drug antibodies were used to bind to free drug molecules in the target solution. The mixture of nanotags and target solution was dropped onto the antigen-modified AuNPM (antigen/AuNPM), and the free nanotags bind to the antigen/AuNPM. By comparing the SERS intensity of 4-MBA with the presence or absence of drug molecules, the drugs were qualitatively and quantitatively identified. Through this category, the LODs for detecting MET, KET, and MOP were 0.1, 1, and 1 ng mL −1 , respectively. This study proposes an effective method for constructing SERS-based detection of drug molecules with good potential for practical applications. Graphical abstract
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MOLECULES
·
2024
·Vol. 29
·期 17
·4051
·
IF 4.2
Chunxia Qi,Ang Li,Baoming Wu,Peisan Wang
Multifunctional targeted drug delivery systems have been explored as a novel cancer treatment strategy to overcome limitations of traditional chemotherapy. The combination of photodynamic therapy and chemotherapy has been shown to enhance efficacy, but the phototoxicity of traditional photosensitizers is a challenge. In this study, we prepared a multi-sensitive composite hydrogel containing gold nanoclusters (Au NCs) and the temperature-sensitive antitumor drug 5-fluorourac il (5-FU) using carboxymethyl cellulose (Carr) as a dual-functional template. Au NCs were synthesized using sodium borohydride as a reducing agent and potassium as a promoter. The resulting Au NCs were embedded in the Carr hydrogel, which was then conjugated with lactobionic acid (LA) as a targeting ligand. The resulting Au NCs/5-FU@Carr-LA composite hydrogel was used for synergistic photodynamic therapy (PDT), photothermal therapy (PTT), and chemotherapy. Au NCs/5-FU@Carr-LA releases the drug faster at pH 5.0 due to the acid sensitivity of the Carr polymer chain. In addition, at 50 °C, the release rate of Au NCs/5-FU@Carr-LA is 78.2%, indicating that the higher temperature generated by the photothermal effect is conducive to the degradation of Carr polymer chains. The Carr hydrogel stabilized the Au NCs and acted as a matrix for drug loading, and the LA ligand facilitated targeted delivery to tumor cells. The composite hydrogel exhibited excellent biocompatibility and synergistic antitumor efficacy, as demonstrated by in vitro and in vivo experiments. In addition, the hydrogel had thermal imaging capabilities, making it a promising multifunctional platform for targeted cancer therapy.
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CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Menglu Jiao,Xiaoyu Mu,Si Sun,Haiyu Yang,Lufei Ouyang,Shaofang Zhang,Jiao Guo,Jian Meng,Ya Liu,Huizhen Ma,Hao Wang,Jiahui Pei,Ruoli Zhao,Tianyu Liu,Wei Long,Xiao-Dong Zhang,Ruiping Zhang
Modulation of radiation biological process at atomic and molecular level is closely related to biocatalytic process, redox biology and multisystem inflammation. Thus, it is necessary to clarify the exact relationship between the biocatalytic process and radiation biology, and further establish the corresponding intrinsic mechanism. In this work, we employed a serial of single atom substitutional gold clusters, which show different biocatalytic activity and selectivity for radiation induced redox modulation. The single atomic Er-substituted Au clusters show the highest antioxidant activity, and clearance rate to reactive oxygen and nitrogen species (RONS), such as peroxynitrite (ONOO − ), nitric oxide ( NO) and hydroxyl radicals ( OH). Meanwhile, single atomic Cu- or Pt-substituted Au clusters exhibit excellent catalase-like (CAT-like) activity. Moreover, the single atomic Pt-substituted Au clusters also show the best ability to oxidate H 2 O molecules to OH − . Biological experiments show that Er-substituted Au clusters have good radioreduction ability, which can increase the survival rate of irradiated mice from 40% to 90%. On the contrary, Au clusters substituted by Cu or Pt have the effect of promoting radioxidation, reducing the survival rate of mice to 30% and 0%. These results suggest that antioxidant capacity, RONS scavenging ability and reducibility are closely related to radioreduction, while CAT-like activity and oxidativeness promote radioxidation.
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TALANTA
·
2024
·
IF 5.6
Anni Cui,Jialu Zhang,Zhifei Liu,Xin Mu,Xiahua Zhong,Haitao Xu,Guiye Shan
Epinephrine (EP) is a crucial neurotransmitter in the central nervous system. However, an abnormal level of EP in biological fluids can lead to various diseases. Therefore, it is essential to rapidly and accurately detect EP content. Herein, electrically stimulated patterned Au@Ag nanoarrays with laccase-mimicking activity were designed for the dual-mode detection of EP concentration. The patterned Au@Ag nanoarrays exhibit excellent electrochemical properties and electrically stimulated laccase-mimicking activity. They provide sensitive electrochemical responses for detecting EP content. Simultaneously, the Au@Ag nanoarrays can catalyze the oxidation of EP, enabling its detection through a colorimetric process. This dual-mode approach achieves the detection of EP content over a wide linear range of 0.5–200 μM, with a low detection limit of 0.152 μM. Furthermore, the utility of these nanoarrays for sensing EP in human serum was evaluated. This work provides a convenient method using patterned nanozyme array for the visible, rapid and accurate detection of EP content. It provides the important implication for the development of portable and reliable on-site analytical instruments.
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ACS Applied Nano Materials
·
2024
·
IF 5.3
Zhiwei Wang,Yefan Zhou,Junsheng Wang,Yun Wang,Jianwei Zhao,Wenjia Xu,Yuhua Feng
Currently, hybrid noble metal nanostructures have garnered significant interest due to their exceptional properties and diverse applications in fields such as catalysis, energy conversion, plasmonic sensing, and surface-enhanced Raman scattering (SERS). In this work, we report the highly site-specific growth of a single Ag island on both the concave face and the sharp tip of concave Au nanocube (c-AuNC) seeds, resulting in different c-AuNC-Ag Janus heterostructures. This site specificity was achieved by combining the surface curvature effect of the c-AuNCs with strong ligand-mediated interfacial energy control. Further integration of interfacial energy and growth kinetic control led to the formation of c-AuNC-(Ag)n core–satellite structures with varying numbers of Ag satellites. Benefiting from the continuous tunability of the interfacial energy and growth kinetics, the structural evolution of the c-AuNC-Ag hybrid structures continuously occurred, enabling precise control of the Au–Ag bimetallic structures. Notably, the resulting c-AuNC-Ag structures showed tunable intense localized surface plasmon resonance (LSPR) absorptions within the 400–1000 nm wavelength along with strong SERS signals. The broad spectral absorption and strong SERS made the c-AuNC-Ag structures promising candidates for SERS and LSPR-based applications, including sensing, imaging, light energy harvesting, and conversion. Moreover, the effective synthetic control demonstrated in this work could facilitate the development of advanced hybrid metal nanomaterials with valuable properties, further broadening their application potential across various fields.
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