CHEMICAL ENGINEERING JOURNAL
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2025
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IF 13.2
Chuntao Yang,Kaiyong Feng,Jiangchang Chen,Ze Liu,Yingjian Yu
The commercial applications of aqueous rechargeable zinc-ion batteries (ZIBs) remain limited mainly owing to the low capacity storage efficiency and structural deformation of cathode materials, coupled with anode dendrite formation and side reactions that compromise battery performance. Herein, the electronically conductive metal-organic framework (EC-MOF) DDA-Cu was developed and used as the cathode for the first time in ZIBs. The electrode material showed an excellent initial discharge capacity of 249.6 mAh g −1 at 0.2 A g −1 . Notably, it also reached a effective capacity of 120 mAh g −1 after 175 cycles at an increased current density of 1 A g −1 . When used as an interface protective coating for zinc anodes, the uniform pore channels of DDA-Cu facilitated homogeneous zinc-ion deposition, which effectively suppressed dendrite growth and side reactions, typically a hydrogen evolution reaction (HER). Compared with bare zinc anodes, the Zn@DDA-Cu anode significantly extended battery lifespan, demonstrating stable cycling for over 3500 h at 0.5 mA cm −2 . Notably, the full battery with a Zn@DDA-Cu anode and a DDA-Cu cathode exhibited stable cycling for 100 cycles at 1 A g −1 , retaining a capacity of 185.5 mAh g −1 . This study provides an innovative strategy for the development of promising EC-MOFs for practical ZIB application.
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高影响因子
POLYMER BULLETIN
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2025
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IF 4
Shah Nouman Ali,Shakir Namra,Gul Rizwan M.,Xu Jia-Zhuang,Li Zhong-Ming
Ultra-high molecular weight polyethylene (UHMWPE) is a versatile polymer with various industrial applications, particularly in orthopedic implants and structural materials. However, its susceptibility to oxidation limits its utility in demanding environments. This study investigates the potential of d -sorbitol (DS), a natural polyol, in enhancing the oxidation stability and crosslink density of UHMWPE when stabilized with tea polyphenols. Tea polyphenols, such as epigallocatechin gallate (EGCG), have been previously evaluated as a promising candidate to stabilize UHMWPE against oxidation without affecting its crosslink density. However, the higher content of EGCG has adverse effect on its mechanical properties. It is hypothesized that addition of DS to EGCG can improve the oxidation and crosslink density of UHMWPE blends. For this purpose, EGCG/DS was blended with UHMWPE at low antioxidant concentrations (≤ 1 wt%), and its comprehensive performance was evaluated. Results demonstrate that the incorporation of d -sorbitol effectively retards oxidation-induced degradation in tea polyphenol-stabilized UHMWPE. The presence of d -sorbitol enhances the crosslink density within the polymer matrix, thereby improving its resistance to oxidative stress. Furthermore, the study elucidates the underlying mechanisms through which DS interacts with EGCG and UHMWPE, elucidating the formation of stable complexes that mitigate oxidative damage. The in vitro biocompatibility of the blends was also very promising for use in artificial joints.
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DYES AND PIGMENTS
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2025
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IF 4.2
Yizhi Shao,Dandan Liu,Qinwei Xia,Zhendong Song,Wei Chen,Ke Sun,Changjiang Zhou,Yangyang Xu,Tao Gong
The elongation of π-conjugation could efficiently enhance the photophysical performances or photochemical reactivties of organic molecules, which adapts to the requests of both designing fluorescent materials and organic photoinitiators (PIs). However, there is no work attempted to design organic PIs with large molar extinction coefficients and long π-conjugation lengths by using hybridized local and charge-transfer (HLCT) method, which is meaningful to obtain high-performance PIs with significant fluorescence/photoluminence properties. What's more, how to overcome the obstacles derived from the unbalance between high triplet concentrations and photoinitiation abilities of organic PIs seems to be crucial, while PI's design from a view of excited state were rarely reported for rational regulation strategy up to now, we thus introduced four chromophores with D-A structures designed by HLCT method, whose triplet states were confirmed by Ultra-fast absorption spectroscopy, into photopolymerzation, where LEDs in various wavelengths were utilized as the light sources in the present work. Noticeably, some of these dyes could furnish high monomer conversions and rapid photopolymerization rates, not only under the irradiation of 405 nm LED, but also long-wavelength light source at 660 nm, which have been confirmed by the photopolymerization kinetics and 3D printing technique. Here, the spin-orbit coupling (SOC) coefficients were carried out as well, to examine their effects on photoinitiation abilities of investigated molecules, which can be regarded as the first attempt to achieving light-harvesting PIs from excited state design. Finally, the corresponding photochemical mechanisms were investigated by steady state photolysis, fluorescence quenching experiments, particularly by frontier orbit energy and distributions to examine the interactions between these dyes with co-initiator/additives in details.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2014
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IF 3.552
Qiang Zhang,Qinfu Zhao,Ying Zhang,Ning Han,Liang Hu,Chen Zhang,Tongying Jiang,Siling Wang
3-D ordered macroporous (3DOM) materials were customized for BSA adsorption and further oral immunization. These carriers have a high adsorption capacity and our customized carrier showed a distinctive double-plateau adsorption behavior. Different BSA release rates (between the two plateaus) could be obtained by adjusting the ratio of the protein adsorbed on the internal surface and the external surface. This suggests that the release pattern was determined by the adsorption state. One benefit is that the same carrier could have different release profiles making it possible to study the relationship between the release behavior and adjuvant effects without any distractions. Compared with free BSA alone, a significantly higher level of serum IgG, IgA induced by BSA/3DOM was observed and the release profile had an effect on the immunity. The IgG1 and IgG2a titers suggesting that both the Th1 and Th2 mediated immune response were induced. Therefore, this research could help in the development of a novel inorganic oral adjuvant and provide a new avenue for the administration of oral vaccine.
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PubMed
高影响因子
INTERNATIONAL IMMUNOPHARMACOLOGY
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2014
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IF 2.711
Xiaomin Xia,Chuanyang Su,Juanli Fu,Pu Zhang,Xiaoji Jiang,Demei Xu,Lihua Hu,Erqun Song,Yang Song
This study investigated the protective effect of α-lipoic acid (LA) on lipopolysaccharide (LPS)/ d -galactosamine ( d -GalN)-induced fulminant hepatic failure in mice. First, we found that LA markedly reduced LPS/ d -GalN-induced increases in serum ALT and AST activities, which were supplemented with histopathological examination, suggested that LA has a protective effect on this model of hepatic damage. Livers challenged with LPS/ d -GalN exhibited extensive areas of vacuolization with the disappearance of nuclei and the loss of hepatic architecture. On the contrary, these pathological alterations were ameliorated by LA treatment. Next, we found that ROS and TBARS levels were increased in LPS/ d -GalN treated liver homogenates , which were attenuated by LA administration. Consistently, decreases in hepatic CAT and GPx activities were observed in LPS/ d -GalN group and were significantly restored by LA administration. Moreover, pretreatment with LA markedly reduced LPS/ d -GalN-induced iNOS , COX-2, TNF-α, NF-κB, IL-1β and IL-6 expressions. Furthermore, our data showed that TUNEL-positive cells increased in LPS/ d -GalN-treated mice liver which was counteracted by LA administration. LPS/ d -GalN induced apoptosis of hepatocytes, as estimated by caspase 3, caspase 8 and caspase 9 activations. Also, the increasing of Bax and the decreasing of Bcl-2 expressions also supported LPS/ d -GalN induced apoptosis. Interestingly, LA marked relieved these apoptotic features. Taking together, our results indicated that LA plays an important role on LPS/ d -GalN-induced fulminant hepatic failure through its antioxidant, anti-inflammatory and anti-apoptotic activities.
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PubMed
高影响因子
FOOD CHEMISTRY
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2025
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IF 9.8
Yitong Wang,Keyu Qiu,Ruizi Zhou,Shuxian Bai,Chao Ai,Yanan Zhao,Jesus Simal-Gandara,Hui Teng,Lei Chen
Naringin (NRG), despite their demonstrated health benefits as natural bioactive compounds, are hampered by intrinsic hydrophobicity, which consequently impedes processability in aqueous systems and severely constrains oral bioavailability. The aim of this study was to form different type nanoparticles by Zein, TPGS and NRG, nanoparticles were obtained by the anti-solvent method, and to analyze the internal interaction forces, stability and antioxidative. The sequence of the antisolvents used becomes the primary factor influencing the properties of the nanoparticles. Nanoparticles were characterized by multimodal analysis, as spectroscopy, molecular docking, SEM, XRD, FTIR, TGA, and ITC. NRG is stabilized within the Zein matrix through hydrogen bonding involving Gln residues and hydroxyl or carbonyl groups, coupled with hydrophobic sequestration of its aglycone moiety in Pro-rich nonpolar cavities. The encapsulation efficiency of NRG increased up to 72.71 % at ( Z -N)-T, which is the highest stability among different types of nanoparticles. The nanoparticles average size below 105 nm, and the zeta potential is 25.48 mV, and also exhibits significant antioxidant activity. This study architected Zein-based nanoparticles to methodically assess the interaction force and stability, pioneering a formulation approach for engineered carriers in food and drug delivery matrices.
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PubMed
高影响因子
Food Bioscience
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2025
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IF 5.9
Chenxi Gu,Liyan Yang,Susu Han,Dengfeng Yang,Xiaodong Xu,WenChao Zhang,Mingguo Jiang,Lixia Pan
Cold-active chitinases that maintain robust catalytic performance at low temperatures are gaining attention as eco-friendly biocatalysts for energy-saving bioprocesses. In this study, a novel multifunctional chitinase of GH18 ( Cm Chi18B) was successfully cloned from a newly identified mangrove-associated bacterium Chitinibacter mangrovi FCG-7 T in Escherichia coli . The enzyme Cm Chi18B demonstrated adaptability to cold environments, retaining 55% of its maximal activity at 0°C. It displayed optimal activity at 55°C and pH 5.5. Cm Chi18B demonstrated high activity across a broad pH range of 4.0-12.0. Substrate hydrolysis analysis indicated that Cm Chi18B possesses bi-functional capabilities, including exochitinase and N-acetyl-β-D-glucosaminidase activities. After 24 h of incubation with colloidal chitin at 30°C, the enzyme achieved a N-acetyl-D-glucosamine (GlcNAc) conversion rate of 91.15% with a purity exceeding 98%. Intriguingly, the hydrolysis time for GlcNAc production varied with temperatures, with 0°C significantly impairing N-acetyl-β-glucosaminidase activity. These attributes position Cm Chi18B as a promising, low-energy biocatalyst for the sustainable production of GlcNAc and the valorization of chitin waste streams.
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BIOCHEMICAL ENGINEERING JOURNAL
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2024
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IF 3.7
Yun Liu,Ao Huang,Xiaowei Wen
Phospholipase D (PLD) is essential for the bioconversion of phosphatidylcholine (PC) to phosphatidylserine (PS), a process valuable in functional food and medicine. This study explores the stability and catalytic properties of PLD immobilized on chitosan-encapsulated magnetic nanoparticles (CMNPs), utilizing oxidized dextran (DX) and glutaraldehyde (Glu) as cross-linkers. The cross-linker concentration and immobilization time were optimized to assess their effects on PLD catalytic performance. PLD immobilized on CMNPs with DX (DX-CMNPs-PLD) exhibited optimal activity at pH 8.0 and 30 °C, retaining over 40 % activity after 14 cycles, while Glu-cross-linked PLD (Glu-CMNPs-PLD) retained approximately 65 %. DX-CMNPs-PLD demonstrated superior pH, temperature, and operational stability compared to free PLD. Additionally, the immobilized PLD was characterized using transmission electron microscopy, X-ray diffraction, and Fourier-transform infrared spectroscopy. Kinetics parameters (V max and K m ) of the immobilized PLD were also studied with free PLD serving as a control. Conformational analyses indicated a significant change in PLD's secondary structure, particularly in β-sheet content, which likely contributed to the enhanced stability and activity. These findings suggest a promising approach for PLD immobilization on CMNPs, with notable implications for biotechnological applications.
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高影响因子
ANALYTICA CHIMICA ACTA
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2022
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IF 6.911
Yanan Deng,Zihao Zhang,Yuanhao Pang,Xueying Zhou,Yu Wang,Yun Zhang,Yali Yuan
The poly-L-cysteine modified Au nanoparticles (Au@p-L-Cys) were constructed on electrode surface as a highly efficient chiral interface for tryptophan (Trp) enantiomers recognition via one step electropolymerization. With the aid of Cu 2+ , L-Cys residues and D-Trp target formed a sandwich complex D-Trp-Cu 2+ -L-Cys, while L-Trp was unable to form such complex due to the steric hindrance provided by the chiral interface, which was confirmed by the electrochemical and SEM results. With the introduction of ferricyanide probe, D-Trp produced significant current decrease while L-Trp produced a slight current increase, which implied the successful enantioselective recognition of Trp enantiomers (specifically D-Trp) in the true sense. This novel sensor showed a surprisingly wide linear range toward D-Trp of 6 × 10 −7 M to 1 × 10 −2 M, with a detection limit as low as 75 nM (S/N = 3). Moreover, the exclusive enantioselectivity toward D-Trp was discovered since other amino acids showed negligible interference to detection of D-Trp. The recovery of D-Trp in human serum was between 91.30 and 109.3%, which further verified the satisfying specificity and practicality of the proposed strategy. The coordination thermodynamics by UV–Vis spectroscopy and DFT simulation were also used to investigate the enantioselective mechanism. These results highlight the great potential of using Au@p-L-Cys to construct chiral interface for enantiomers recognition and hold the promise of practical application of electrochemical chiral sensors in fields like pharmaceutics and bioanalysis .
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高影响因子
Frontiers in Microbiology
·
2024
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IF 4
Yuhan Zheng,Feiyang Sun,Siyi Liu,Gang Wang,Huan Chen,Yongxin Guo,Xiufeng Wang,Maia Lia Escobar Bonora,Sitong Zhang,Yanli Li,Guang Chen
Background: The production of D-lactic acid (D-LA) from non-detoxified corn stover hydrolysate is hindered by substrate-mediated inhibition and low cell utilization times. In this study, we developed a novel temperature-sensitive hydrogel, F127-IEA, for efficient D-LA production using a cell-recycle batch fermentation process.Results: F127-IEA exhibited a porous structure with an average pore size of approximately 1 μm, facilitating the formation of stable Lactobacillus bulgaricus clusters within the gel matrix. It also maintains excellent mechanical properties. It also maintains excellent mechanical properties. F127-IEA immobilized Lactobacillus bulgaricus T15 (F127-IEA-T15) can be used in cell-recycle fermentation for over 150 days from glucose and 50 days from corn stover hydrolysate, achieving high production rates of D-LA from glucose (2.71 ± 0.85 g/L h) and corn stover hydrolysate (1.29 ± 0.39 g/L h). F127-IEA-T15 enhanced D-LA production by adsorbing and blocking toxic substances present in corn stover hydrolysate that are detrimental to cellular activity.Conclusions: The newly developed hydrogels in this study provide a robust platform for large-scale extraction of D-LA from non-detoxified corn stover.
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PubMed
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2025
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IF 8.3
Yixin Sun,Jiawen Liu,Xinyang Xu,Zhonghua Li
In the strategies of modifying g-C 3 N 4 by changing its electron transport structure, it has been demonstrated that constructing donor-acceptor (D-A) or D-π-A g–C 3 N 4 –based conjugated copolymers can obviously accelerate the separation of charge carriers. Inspired by their advantages, a novel g–C 3 N 4 –based D-A 1 -π-A 2 type polymer was designed and synthesized via the thermal copolymerization of urea and PA-PM (the product of the amidation reaction between PA and PM). As a result, the prepared CN-PA-PM photocatalysts with D-A 1 -π-A 2 structure not only improve visible-light response, but also promote the separation of charge carriers, thereby achieving superior photocatalytic hydrogen evolution activity. The optimized CN-PA-PM-13 polymer has the best hydrogen evolution efficiency of 17.79 mmol g −1 h −1 under visible light (λ > 420 nm), which is 33.7 times that of pure g-C 3 N 4 . This work presents a new design concept for g–C 3 N 4 –based polymer photocatalysts with high optical absorption capability and effective carrier separation ability.
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高影响因子
JOURNAL OF CATALYSIS
·
2025
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IF 6.5
Chengliang Wang,Xia Guo,Jinbian Lv,Yin Zhang,Haitao Li,Jie Gao,Wei Wei,Di Zhang,Yongxiang Zhao
The primary products of the direct hydrogenation of Maleic Anhydride (MA) are Succinic Anhydride (SAH) and γ-butyrolactone (GBL). Achieving selective synthesis of these products by regulating the composition, structure, and textural properties remains a focal point in the research field of maleic anhydride hydrogenation. Based on the characteristic of atomic level uniform distribution of cations of layered double hydroxides (LDHs), a highly loaded, highly dispersed and homogenized NiCu alloy bimetallic catalyst was synthesized using NiCuAl-LDHs as precursor. Compared with Ni/Al 2 O 3 catalyst derived from NiAl-LDHs, the introduction of Cu can effectively improve the hydrogenation activity of C=C bonds while inhibiting the hydrogenolysis of C=O bonds. Under identical reaction conditions, the primary product of the Ni/Al 2 O 3 catalyst was γ-butyrolactone (GBL) with a yield of 94.2 %, whereas the primary product of the NiCu 0.4 /Al 2 O 3 catalyst was Succinic Anhydride (SAH) with a yield of 90.5 %. The introduction of Cu resulted in the formation of a homogeneous NiCu alloy phase in the catalyst, which significantly influenced the adsorption configurations and adsorption energies of the reactants and intermediates. This effect can be attributed to the electronic interactions between Ni and Cu, which shift the d-band center of Ni away from the Fermi energy level, thereby facilitating the directed synthesis of Succinic Anhydride (SAH) and γ-butyrolactone (GBL). These findings were confirmed by various characterization techniques and DFT theoretical calculations. Future catalyst development in maleic anhydride hydrogenation will significantly benefit from the design approach and research ideas presented in this study.
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危险品化学品经营许可证（带存储）