Journal of Biobased Materials and Bioenergy
·
2016
·Vol. 10
·期 5
·378-384
·
IF 0.635
Chen Wei,Jiang Yetao,Sun Yong,Wang Yanjun,Li Zheng,Wang Xiaoyu,Zeng Xianhai,Liu Shijie,Lin Lu
5-Dimethylaminomethyl-2-Furanmethanol (DMMF) is an essential precursor for the production of ranitidine, a drug for gastropathy. Herein a facile pathway to the value-added pharmaceutical intermediate DMMF from carbohydrates, such as glucose and fructose, was developed for the first
time. The reaction was carried out under catalyst-free conditions using N, N-dimethyl formamide (DMF) as the amine donor in formic acid (FA). A plausible reaction mechanism from carbohydrates to DMMF was also proposed.
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高影响因子
JOURNAL OF CATALYSIS
·
2019
·
IF 7.723
Kaikai Liu,Hongliang Xin,Minghan Han
The phosphorus (III) ligands were crucial for the further improvement of homogeneous nickel catalysts that were employed in the isomerization of 2-methyl-3-butenenitrile (2M3BN) to 3-pentenenitrile (3PN). The catalytic behavior of 1,4-bis(diphenylphosphino)butane (dppb 1 )Ni complex was improved in cumene and the conversion of 2M3BN showed zero-order kinetic. The mechanism behind the isomerization was amended and the density functional theory (DFT) calculations suggested that the reductive elimination step forming 3PN was kinetically relevant in catalytic cycles. An optimal bite angle of nickel-diphosphine complex around 104.7° provided excellent catalytic performance. The key factors governing isomerization were unraveled. The steric effect determined the reactivity, while the electronic effect governed the selectivity of the isomerization reaction. The bite angle – a vital descriptor – would associate with the steric and electronic effects of diphosphines. These structure-activity relationships provided important guidance for ligand design in the isomerization of 2M3BN.
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RSC Advances
·
2015
·Vol. 5
·期 20
·15668-15673
·
IF 3.84
Xian-Dong Lang,Shuai Zhang,Qing-Wen Song,Liang-Nian He
An easily prepared amino acid ionic liquid (AAIL) i.e. [TBP][Arg] comprising a tetra-butylphosphonium cation and an arginine anion was found to be an efficient and recyclable catalyst for the synthesis of quinazoline-2,4(1H,3H)-diones from 2-aminobenzonitriles and CO2 under solvent-free conditions. As a result, various 2-aminobenzonitriles bearing electron-withdrawing or electron-donating substituents worked well to afford quinazoline-2,4(1H,3H)-diones in excellent yields. Notably, this type of AAIL showed good stability, and could be easily recovered and reused five times without significant loss of its catalytic activity. This process represents an alternative approach for greener chemical fixation of CO2 to afford valuable compounds.
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Journal of the American Chemical Society
·
2018
·
IF 14.357
Mei-Ling Feng,Debajit Sarma,Yu-Jie Gao,Xing-Hui Qi,Wei-An Li,Xiao-Ying Huang,Mercouri G. Kanatzidis
Unconventional ion exchangers can achieve efficient removal of [UO2]2+, Cs+, and Sr2+ ions from complex aqueous solutions and are of great interest for environmental remediation. We report two new gallium thioantimonates, [Me2NH2]2[Ga2Sb2S7]·H2O (FJSM-GAS-1) and [Et2NH2]2[Ga2Sb2S7]·H2O (FJSM-GAS-2), which present excellent ion exchange properties for [UO2]2+, Cs+, and Sr2+ ions. They exhibit high ion exchange capacities for [UO2]2+, Cs+, and Sr2+ ions (qmU = 196 mg/g, qmCs = 164 mg/g, and qmSr = 80 mg/g for FJSM-GAS-1, qmU = 144 mg/g for FJSM-GAS-2) and short equilibrium times for [UO2]2+ ion exchange (5 min for FJSM-GAS-1 and 15 min for FJSM-GAS-2, respectively). Both compounds display active ion exchange with [UO2]2+ in the pH range of 2.9–10.5. Moreover, the sulfide compounds could maintain high distribution coefficients KdU even in the presence of excess Na+, Ca2+, and HCO3–. The distribution coefficient KdU of 6.06 × 106 mL/g exhibited by FJSM-GAS-1 is the highest among the reported U adsorbents. The [UO2]2+-laden products can be recycled by conveniently eluting the uranium with a low-cost method. These advantages combined with facile synthesis, as well as β and γ radiation resistance, make FJSM-GAS-1 and FJSM-GAS-2 promising for selective separations in nuclear waste remediation.
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PubMed
高影响因子
AMERICAN JOURNAL OF NEPHROLOGY
·
2023
·
IF 4.2
Shi Heng,Zhao Xinhai,Peng Qin,Zhou Xianling,Liu Sisi,Sun Chuanchuan,Cao Qiuyu,Zhu Shiping,Sun Shengyun
Introduction: Di(2-ethylhexyl) phthalate (DEHP) is a common plasticizer. Studies have revealed that DEHP exposure can cause kidney damage. Green tea is among the most popular beverages in China. Green tea polyphenols (GTPs) have been proven to have therapeutic effects on organ damage induced by heavy metal exposure. However, few studies have reported on GTP-relieving DEHP-induced kidney damage. Methods: C57BL/6J male mice aged 6–8 weeks were treated with distilled water (control group), 1,500 mg/kg/d DEHP + corn oil (model group), 1,500 mg/kg/d DEHP + corn oil + 70 mg/kg GTP (treatment group), corn oil (oil group), and 70 mg/kg GTP (GTP group) by gavage for 8 weeks, respectively. The renal function of mice and renal tissue histopathology of each group were evaluated. The renal tissues of mice in the model, treatment, and control groups were analyzed using high-throughput sequencing. We calculated the differentially expressed microRNAs (miRNAs) and messenger RNAs (mRNAs) using the limma R package, the CIBERSORT algorithm was used to predict immune infiltration, the starBase database was used to screen the miRNA-mRNA regulatory axis, and immunohistochemical analyses were performed to verify protein expression. Results: GTP alleviated the deterioration of renal function, renal inflammation and fibrosis, and mitochondrial and endoplasmic reticulum lesions induced by DEHP in mice. Differential immune infiltrations of plasma, dendritic, T, and B cells were noted between the model and treatment groups. We found that three differentially expressed miRNAs (mmu-miR-383-5p, mmu-miR-152-3p, and mmu-miR-144-3p), three differentially expressed mRNAs (Ddit4, Dusp1, and Snx18), and three differentially expressed proteins (Ddit4, Dusp1, and Snx18) played crucial roles in the miRNA-mRNA-protein regulatory axes when GTPs mitigate DEHP-induced kidney damage in mice. Conclusion: GTP can alleviate DEHP-induced kidney damage and regulate immune cell infiltration. We screened four important miRNA-mRNA-protein regulatory axes of GTP, mitigating DEHP-induced kidney damage in mice
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PubMed
高影响因子
SYNTHESIS-STUTTGART
·
2020
·Vol. 53
·期 07
·1341-1348
·
IF 2.675
Xinxin Zhao,Lin Guo,Chao Yang,Wujiong Xia
A highly regioselective [3+2] cyclization of alkenes with 2-iodoanilines under the irradiation of UV light is described. This general, metal-free strategy facilitates the direct preparation of 2-mono-/disubstituted indolines as well as spiroindolines through alkene carboamination in one step. Mechanistic studies suggested that the photochemical protocol proceeded via a radical pathway.
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高影响因子
JOURNAL OF CHEMICAL RESEARCH
·
2018
·
IF 0.668
Da-Hua Shi,Xiao-Dong Ma,Yu-Wei Liu,Wei Min,Fu-Jun Yin,Zong-Ming Tang,Meng-Qiu Song,Chen Lu,Xiao-Kai Song,Wei-Wei Liu,Tong Dong
To find novel butyrylcholinesterase inhibitors, three novel 2-phenylthiazole derivatives were synthesised. The synthesised compounds were characterised by NMR and single-crystal X-ray diffraction analysis. Hirshfeld surface analysis and two-dimensional fingerprint plots of the compounds were used as a theoretical approach to assess the driving force for crystal structure formation via the intermolecular interactions in the crystal lattices of the synthesised compounds. Among the three compounds, N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro- 1H-pyrazol-4-yl)-2-(4-methoxyphenyl)thiazole-4-carboxamide showed the best butyrylcholinesterase-inhibition activity with an IC50 value of 75.12 μM. A docking study demonstrated that this compound interacts with the peripheral anionic site of butyrylcholinesterase.
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高影响因子
JOURNAL OF LUMINESCENCE
·
2022
·
IF 4.171
Xueai Yin,Shuchen Lü
In this study, Sr 0.3 Ca 0.7 (MoO 4 ) 2 :xDy 3+ , yEu 3+ phosphors with and without charge compensation were produced using the coprecipitation method. Their crystal structure, luminescence performances, charge compensation, fluorescence lifetime , thermal extinguishing behavior as well as energy transfer mechanism were explored in detail. The X-ray diffraction patterns show that the appropriate amount of Dy 3+ /Eu 3+ single and co-doped in the lattice has no obvious influence on the crystal structure. The luminescence results showed that Sr 0.3 Ca 0.55 (MoO 4 ) 2 : 0.1Eu 3+ with charge compensation exhibited luminescence intensity 4.98 times higher than that of Sr 0.3 Ca 0.6 (MoO 4 ) 2 : 0.1Eu 3+ non-charge compensation. The luminescence intensity of Dy 3+ /Eu 3+ co-doped Sr 0.3 Ca 0.7 (MoO 4 ) 2 phosphors was significantly improved by charge compensation. Furthermore, efficient energy transfer from Dy 3+ → Eu 3+ was confirmed by emission spectra , excitation spectra, attenuation curves, and thermal quenching curves. This suggests that the charge compensation could significantly improve the Eu 3+ red emission. Therefore, the investigated SrCa(MoO 4 ) 2 : Eu 3+ , Dy 3+ phosphors may be a favorable candidate for promising applications in lighting.
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高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2018
·
IF 3.779
Jiaguang Zheng,Xuezhang Xiao,Yan He,Man Chen,Meijia Liu,Shouquan Li,Lixin Chen
The Mg(BH 4 ) 2 -AlH 3 - x LiH ( x = 0, 0.5, 1) novel ternary composites have been synthesized through mechanical ball milling, their favorable dehydrogenation properties and mechanism have been experimentally investigated. It can be found that during ball milling, a slight amount of Mg(BH 4 ) 2 would react with LiH and transform into LiBH 4 , while most Mg(BH 4 ) 2 remained stable after ball milling. Two major dehydrogenation steps can be detected in the Mg(BH 4 ) 2 -AlH 3 - x LiH composite, which belong to the decomposition of AlH 3 and Mg(BH 4 ) 2 , respectively. Remarkably, the onset hydrogen desorption temperature of Mg(BH 4 ) 2 -AlH 3 - x LiH composite can be reduced to 125.9 °C, with a total hydrogen desorption capacity of 10.3 wt%. It is worth emphasizing that the reversible dehydrogenation capacity is obviously improved to 3.8 wt%, compared to the Mg(BH 4 ) 2 -AlH 3 composite. This reversible capacity can be held for 3 cycles without obvious degeneration. Microstructural analysis on de/rehydrogenated composite has identified the regeneration of [BH 4 ] - in Mg(BH 4 ) 2 -AlH 3 -0.5LiH composite and revealed the role of LiH in the cycling hydrogen desorption and absorption processes. The formation of LiBH 4 and MgH 2 resulted from the rehydrogenation between MgAlB 4 and LiH could be helpful for the stability of reversible hydrogen storage performance.
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ECS Journal of Solid State Science and Technology
·
2021
·Vol. 10
·期 10
·106011
·
IF 2.07
Jie Yang,Bo Ruan,Wang Ni,Lung-Chang Tsai,Ning Ma,Dean Shi,Tao Jiang,Fang-Chang Tsai
Carbon dots (CDs) has been widely applied in LED diodes, sensing and bioimaging. However, the fluorescence property of CDs is limited because of the solid-state aggregation-caused quenching (ACQ). Metal-organic frameworks (MOFs), due to their high surface area, porosity and tunable pore size, are considered suitable hosts to inhibit the ACQ of CDs. Herein, the Zr-MOFs (UiO-66-(OH)2) is chosen as a host to encapsulate CDs. The dual-emitting CDs@MOFs system is constructed, which overcomes the problem of solid-state aggregation-caused quenching of carbon dots to gain the blue-emitting CDs@UiO-66-(OH)2. With the volume of CDs increased, the fluorescence of CDs@UiO-66-(OH)2 has changed simultaneously. When the volume reaches 3 ml, CDs@UiO-66-(OH)2 begin to cause fluorescence quenching. The correlated color temperatures (CCT) of CDs@UiO-66-(OH)2 are transformed from cold light to warm light. That can be further researched in electroluminescent diodes, ion-sensor, environmental monitoring, biological imaging and developments in other related biochemical fields.
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Research
·
2023
·
IF 11
Guangchun Song,Jia Xu,Hong Zhong,Qi Zhang,Xin Wang,Yitong Lin,Scott P. Beckman,Yunbo Luo,Xiaoyun He,Jin-Cheng Li,Kunlun Huang,Nan Cheng
The enzyme-mimicking catalytic activity of single-atom nanozymes has been widely used in tumor treatment. However, research on alleviating metabolic diseases, such as hyperglycemia, has not been reported. Herein, we found that the single-atom Ce-N4-C-(OH)2 (SACe-N4-C-(OH)2) nanozyme promoted glucose absorption in lysosomes, resulting in increased reactive oxygen species production in HepG2 cells. Furthermore, the SACe-N4-C-(OH)2 nanozyme initiated a cascade reaction involving superoxide dismutase-, oxidase-, catalase-, and peroxidase-like activity to overcome the limitations associated with the substrate and produce •OH, thus improving glucose intolerance and insulin resistance by increasing the phosphorylation of protein kinase B and glycogen synthase kinase 3β, and the expression of glycogen synthase, promoting glycogen synthesis to improve glucose intolerance and insulin resistance in high-fat diet-induced hyperglycemic mice. Altogether, these results demonstrated that the novel nanozyme SACe-N4-C-(OH)2 alleviated the effects of hyperglycemia without evident toxicity, demonstrating its excellent clinical application potential.
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高影响因子
NEW JOURNAL OF CHEMISTRY
·
2020
·Vol. 44
·期 37
·15908-15918
·
IF 3.288
Xiuna Yu,Zhixiang Liu,Yemei Wang,Hongyu Luo,Xu Tang
Insights into active sites and charge transport behavior are challenging topics for fabricating composite photocatalysts and investigating their photocatalytic degradation reaction mechanisms. Herein, novel composites comprising biomass charcoal and graphitic carbon nitride (CN) were fabricated via facial alkali catalysis and thermal condensation of corncob and melamine precursors. By fine-tuning the calcination temperature, the carbonization temperature of corncob-derived biomass charcoal was controlled, which had a great influence on the optimal photocatalytic activity of C–CN-600, which was 90% of the degradation activity of 2-mercaptobenzothiazole (MBT), and about 2-fold higher than that of pure CN. The corncob not only acts as a precursor for biomass charcoal, but can also prevent the agglomeration of CN at high temperature. Moreover, the charge carrier lifetime, visible light absorption and surface area are also revealed in detail by systematic characterization. In addition, the intermediate products of MBT, the degradation reaction pathway, and the mechanism over C–CN are revealed in depth.
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高影响因子
危险品化学品经营许可证（带存储）