HIGH PERFORMANCE POLYMERS
·
2019
·
IF 1.584
Huabo Huang,Renpeng Chen,Shuaiyi Yang,Liang Li,Yulan Liu,Juan Huang
To obtain the promising pseudocapacitance of MnO2, the composite hydrogel of MnO2 and polyaniline (PANI) was fabricated using in situ polymerization of aniline hydrochloride in the aqueous solution containing commercial MnO2 nanoparticles and additives. Both scanning electron microscopy and transmission electron microscopy results indicated that the composite hydrogel exhibited a 3-D porous structure, within which MnO2 nanoparticles were uniformly embedded. The investigations of cyclic voltammetry, galvanostatic charge−discharge, and electrochemical impedance spectroscopy demonstrated superior supercapacitor (SC) performance of the hydrogel electrode even with high loading. The electrode with loading of 1.5 mg cm–2 showed a favorable specific capacitance (293 F g–1, 10 mV s–1), which only decreased to 258 F g–1 when the loading of the electrode was seven times higher (10.8 mg cm–2). Furthermore, the hydrogel electrode displayed good cycle stability in the acidic solution (81% capacitance retention after 1000 charge/discharge cycles). The favorable electrochemical performance of the composite hydrogel should be attributed to the fast electron/ion transport and good protection for MnO2 in the 3-D porous structure. Due to the facile one-pot synthesis and optimized nanostructure, it could be expected that MnO2-embedded 3-D porous PANI composite hydrogels have great application in the field of high-performance electrode with high loading for SCs.
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APOPTOSIS
·
2019
·Vol. 24
·期 3
·312-325
·
IF 4.021
Zhang Cheng-cheng,Li Chen-guang,Wang Yao-feng,Xu Li-hui,He Xian-hui,Zeng Qiong-zhen,Zeng Chen-ying,Mai Feng-yi,Hu Bo,Ouyang Dong-yun
Gasdermin E (GSDME) has an important role in inducing secondary necrosis/pyroptosis. Upon apoptotic stimulation, it can be cleaved by activated caspase-3 to generate its N-terminal fragment (GSDME-NT), which executes pyroptosis by perforating the plasma membrane. GSDME is expressed in many human lung cancers including A549 cells. Paclitaxel and cisplatin are two representative chemotherapeutic agents for lung cancers, which induce apoptosis via different action mechanisms. However, it remains unclear whether they can induce GSDME-mediated secondary necrosis/pyroptosis in lung A549 cancer cells. Here we showed that both paclitaxel and cisplatin evidently induced apoptosis in A549 cells as revealed by the activation of multiple apoptotic markers. Notably, some of the dying cells displayed characteristic morphology of secondary necrosis/pyroptosis, by blowing large bubbles from the cellular membrane accompanied by caspase-3 activation and GSDME-NT generation. But the ability of cisplatin to induce this phenomenon was much stronger than that of paclitaxel. Consistent with this, cisplatin triggered much higher activation of caspase-3 and generation of GSDME-NT than paclitaxel, suggesting that the levels of secondary necrosis/pyroptosis correlated with the levels of active caspase-3 and GSDME-NT. Supporting this, caspase-3 specific inhibitor (Ac-DEVD-CHO) suppressed cisplatin-induced GSDME-NT generation and concurrently reduced the secondary necrosis/pyroptosis. Besides, GSDME knockdown significantly inhibited cisplatin- but not paclitaxel-induced secondary necrosis/pyroptosis. These results indicated that cisplatin induced higher levels of secondary necrosis/pyroptosis in A549 cells than paclitaxel, suggesting that cisplatin may provide additional advantages in the treatment of lung cancers with high levels of GSDME expression.
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高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2018
·
IF 2.196
Xiangyu Zhang,Neng Gao,Yongping Wu,Guangming Chen
To improve the performance of an absorption system, ionic liquids (ILs) have been chosen as additives to conventional working fluid (lithium bromide aqueous solution) in recent years. In this paper, 1-ethyl-3-methylimidazolium acetate ([Emim]Ac) was added to lithium bromide aqueous solution (mass ratio LiBr/[Emim]Ac = 3) to measure the vapor–liquid equilibrium (VLE) data of the ternary system. The experiment was conducted by means of boiling point method, at temperatures between 303.94 K and 405.41 K and mass fractions of absorbent between 0.20 and 0.60. The experimental data were regressed using an Antoine-type equation, and the average absolute relative deviation (AARD%) between the experimental and calculated values was 0.34%, which showed excellent accuracy and consistency. The experimental ternary system was compared with the conventional LiBr + H2O system and two other ternary systems from the literature; the result revealed that the experimental ternary system had lower vapor pressures, which will benefit the process of releasing latent heat in absorption cycles.
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高影响因子
Materials
·
2018
·Vol. 11
·期 9
·1505
·
IF 2.467
Yan Song,Xu Zong,Nan Wang,Ning Yan,Xueying Shan,Jinchun Li
Lignin can be a candidate as a charring agent applied in halogen-free flame retardant polymers, and incorporation of silicon and nitrogen elements in lignin can benefit to enhancing its thermal stability and charring ability. In the present work, wheat straw alkali lignin (Lig) was modified to incorporate silicon and nitrogen elements by γ-divinyl-3-aminopropyltriethoxysilane, and the modified lignin (CLig) was combined with ammonium polyphosphate (APP) as intumescent flame retardant to be applied in poly(Lactic acid) (PLA). The flame retardancy, combustion behavior and thermal stability of PLA composites were studied by the limited oxygen index (LOI), vertical burning testing (UL-94), cone calorimetry testing (CCT) and thermogravimetric analysis (TGA), respectively. The results showed a significant synergistic effect between CLig and APP in flame retarded PLA (PLA/APP/CLig) occured, and the PLA/APP/CLig had better flame retardancy. CCT data analysis revealed that CLig and APP largely reduced the peak heat release rate (PHRR) and total heat release rate (THR) of PLA, indicating their effectiveness in decreasing the combustion of PLA. TGA results exhibited that APP and CLig improved the thermal stability of PLA at high temperature. The analysis of morphology and structure of residual char indicated that a continuous, compact and intumescent char layer on the material surface formed during firing, and had higher graphitization degree. Mechanical properties data showed that PLA/APP/CLig had higher tensile strength as well as elongation at break.Keywords:wheat straw soda lignin;silicon and nitrogen elements;poly(lactic acid);thermal stability;combustion behavior
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JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2018
·Vol. 102
·期 3
·1414-1424
·
IF 2.956
Yaowu Wei,Tao Zhang,Qi Zhang,Bingqiang Han,Nan Li
Improving the hydration resistance of CaO aggregates is the key to successful application of lime-based refractories in metallurgical industry. Additive Zr(OH) 4 and Al(OH) 3 were introduced in the preparation of CaO granules using granulation equipment and calcination method in this study. The results showed that the hydration resistance of CaO granules was improved significantly, especially for granules with 0.6 wt.% Zr(OH) 4 and 0.9 wt.% Al(OH) 3 , respectively. The shell of CaO granules was relatively dense after calcination and the volume of open pores of CaO granules decreased from 3.56 × 10 −2 to 1.80 × 10 −2 cm 3 /g when additive was introduced. Zr(OH) 4 and Al(OH) 3 have the opposite effect on the closed porosity of CaO granules, the closed porosity of CaO granules was decreased with Zr(OH) 4 addition, but increased with Al(OH) 3 addition.
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高影响因子
Materials Science & Engineering C-Materials for Biological Applications
·
2018
·
IF 5.08
Juan Zhang,Xiao-Tong Guo,Jun-Ping Zhou,Guang-Zhou Liu,Shu-Yong Zhang
A nanocomposite with multi-walled carbon nanotubes (MWCNTs) coated with surface molecularly imprinted polymers (MIPs) poly(3-aminophenylboronic acid) (PAPBA) was successfully prepared via potentiodynamic electropolymerization and tested as an effective electrochemical material for epinephrine (EP) detection. The morphology and properties of the sensing material were characterized with scanning electron microscopy and electrochemical impedance spectroscopy. Compared with MWCNTs or non-imprinted polymers PAPBA modified MWCNTs electrodes, the PAPBA(MIPs)/MWCNTs modified electrode showed a lower charge transfer resistance and enhanced electrochemical performance for EP detection. The improved performance can be attributed to the large amount of specific imprinted cavities with boric acid group which can selectively adsorb EP molecule and the synergistic effect between MWCNTs and PAPBA(MIPs). The effects of pH, the molar ratio between monomer and template molecule, the cycle number of electropolymerization, and the accumulation time of the modified electrode on the sensing performance were investigated. It was found that under the optimal conditions, the PAPBA(MIPs)/MWCNTs sensor could effectively recognize EP from many possible interferents of higher concentration within a wide linear range of 0.2–800 μmol·L −1 , with low detection limit of 35 nmol·L −1 , high sensitivity and good discrimination. The detection of EP in human serum and real injection samples using the PAPBA(MIPs)/MWCNTs sensor also gave satisfactory results.
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高影响因子
JOURNAL OF NANOPARTICLE RESEARCH
·
2018
·Vol. 20
·期 6
·1-9
·
IF 2.127
Wu Xiang-Feng,Li Hui,Su Jun-Zhang,Zhang Jia-Rui,Feng Yan-Mei,Pan Jun-Cheng,Zhang Ying,Sun Li-Song,Zhang Wei-Guang,Sun Guo-Wen
The In 2.77 S 4 microspheres had been firstly fabricated by using polyethylene glycol (PEG) as the morphological modifier and then used to hybridize with In(OH) 3 nanocubes by a simply depositional method. The structure, optical properties, morphology, chemical compositions, and charge carrier behaviors of the as-prepared In 2.77 S 4 /In(OH) 3 composites were characterized, respectively. The methyl orange, tetracycline, rhodamine B, and Cr(VI) dilute solution were selected to evaluate their photocatalytic activities. Experimental results showed that In(OH) 3 nanocubes could improve the photocatalytic activity and recyclability of the In 2.77 S 4 microspheres under the visible light irradiation. With the usage of In(OH) 3 increased, the photocatalytic efficiency of the hybrids was firstly increased and then decreased. When the mass ratios of In 2.77 S 4 to In(OH) 3 were 6:2, it reached the maximum of 100% in 15 min for methyl orange, obviously higher than 67.4% of In 2.77 S 4 and 1.1% of In(OH) 3 . Meanwhile, it could also oxidize 85.6% of tetracycline in 20 min, 97.8% of rhodamine B in 7.5 min, and reduce 92.9% of Cr(VI) in 30 min under the visible light irradiation. Moreover, it could still degrade 91.7% of methyl orange solution after 3 cycles, which was much higher than 40.7% of In 2.77 S 4 microspheres. In addition, the possible mechanism of enhancing photocatalytic properties was proposed.
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高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2018
·
IF 3.909
Haifeng Hu,Liu Yang,Zhen Lin,Xiaotong Xiang,Xiancai Jiang,Linxi Hou
A novel magnetic bioadsorbent beads composed of Fe 3 O 4 , chitosan, and Al(OH) 3 (Fe 3 O 4 /CS/Al(OH) 3 ) was synthesized by a modified solvothermal and in-situ reaction. The composite adsorbent was characterized by Fourier-transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, energy dispersive X-ray spectroscopy, and vibrating sample magnetometer, respectively. Adsorption toward F − onto Fe 3 O 4 /CS/Al(OH) 3 was investigated as a function of Fe 3 O 4 concentration, initial solution pH, adsorbent dosage, initial fluorion concentration, co-existing ions in water and initial temperature. The addition of Fe 3 O 4 could enhance the adsorption properties of CS/Al(OH) 3 . The saturated adsorption capacity of magnetic Fe 3 O 4 /CS/Al(OH) 3 calculated from the Langmuir isotherm model was 76.63 mg/g at 298 K. The adsorption isotherm of F − followed Langmuir isotherm model and the adsorption kinetics fitted better to the pseudo-second order kinetic model. The influence of temperature confirmed that the adsorption was spontaneous and endothermic. The magnetic Fe 3 O 4 /CS/Al(OH) 3 beads could be easily separated from water under a low magnetic field.
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2018
·Vol. 135
·期 46
·46764
·
IF 1.901
R. Zhang,L. Wang,C. Zhang,R. Yang,X. Sun,B. Song,C.-P. Wong,Y. Xu
A novel kind of conductive self-assembled colloid particles (CPs) was prepared from poly(3-thiophenecarboxylic acid) (PTPCA) and chitosan (CS) via electrostatic interaction and π–π interaction. The resultant CPs were then cast on the electrode surface to provide a platform for fabricating high-sensitive biosensor. It should be noted that the good conductivity of PTPCA can accelerate the electron transfer and facilitate the signal transduction from the CP film to the underlying electrode. This advantage endowed the biosensor with high sensitivity for H 2 O 2 detection. Under the optimal conditions, a linear range from 1 × 10 −11 to 1 × 10 −5 mol L −1 with a detection limit of 3 × 10 −12 mol L −1 was obtained for H 2 O 2 detection. The biosensor can be used to detect H 2 O 2 in commercial disinfector with satisfactory results. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018 , 135 , 46764.
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Nano Research
·
2019
·Vol. 12
·期 8
·1937-1942
·
IF 8.515
Sun Hongxia,Du Haoran,Yu Mengkang,Huang Kuangfu,Yu Nan,Geng Baoyou
Vesicular lithium vanadium phosphate/carbon hollow mesoporous microspheres were fabricated using a facile polyvinylpyrrolidone-assisted aerosol-spray-assisted method and subsequent heat-treatment. While changing the content of polyvinylpyrrolidone, we found that carbon content was adjustable on the surface of lithium vanadium phosphate. By optimizing the carbon content among the composites, the electrochemical performance can be enhanced significantly. The results of electrochemical performance tests suggested that the samples exhibited good cycle performance and high discharge capability in the voltages between 3.0–4.8 V. The observed excellent electrochemical performances could be attributed to the proper content of carbon coating and the vesicular hollow mesoporous microsphere structure, increasing the transmission rate of lithium ions and reducing the structural change during charging and discharging effectively.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2019
·
IF 2.931
Jing Zou,Yixin Huang,Lirong Zhu,Zheng Cui,Baoling Yuan
A spectrophotometric method using 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonate) (ABTS) as the indicator was proposed for measuring persulfates, i.e., peroxymonosulfate (PMS) and peroxydisulfate (PDS). This method was based on the direct oxidation of the colorless ABTS by PMS/PDS to generate the green-colored ABTS + at neutral pH and room temperature . The generated ABTS + had four different characteristic absorption peaks at 820 nm, 732 nm, 650 nm and 415 nm. The absorption values at these wavelengths increased with the increase of PMS/PDS concentration, and there were well linear relationships (R 2 > 0.998) between the corresponding absorption values and the concentrations of PMS/PDS in the range of 3–500 μM. Monitoring the change of PMS/PDS concentration by the proposed ABTS method was in good agreement with that monitored by the common spectrophotometric method using potassium iodide as the indicator. The green-colored waste solutions produced after PMS/PDS analysis with the ABTS method showed no bactericidal effect towards Escherichia coli . The proposed multi-wavelength spectrophotometric method using ABTS as the indicator could be employed as a candidate method for the accurate and convenient measurement of PMS/PDS in water.
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高影响因子
CHEMISTRY-A EUROPEAN JOURNAL
·
2018
·Vol. 24
·期 52
·13830-13838
·
IF 5.16
Xiangming Li,Yihe Zhang,Zequn Ma,Meng Fu,Qi An
Graphical The heat is on : A facile and efficient approach for the preparation of pH responsive self-assembled (electrostatic interactions) rGO-polymer-DOX nanocomposites for photothermal and chemical therapy is reported (see figure). The development of well-controlled drug carriers that are stable and highly effective for the delivery of anticancer agents is challenging. Herein, we report a novel pH-controlled drug delivery system, utilizing reducing graphene oxide (rGO)-polymer self-assembly films as carriers, for the preparation of effective drug nanorods and nanoparticles. In this system, the rGO-polymer carriers were constructed by the alternating assembly of poly- l -lysine (PLL) and polyaspartic acid (PASP) around the rGO sheets. Furthermore, the rGO-polymer cores, which possess a positively charged surface as the desired template, could assemble with negatively charged doxorubicin (DOX) via electrostatic interactions. The DOX embedding efficiency and the morphology of the drug nanocomposites could be controlled by the number of rGO-polymer bilayers and concentration of the rGO-polymer bilayers and the initial DOX concentration. Importantly, the release of DOX could be regulated by controlling the pH and by using a NIR laser. Under acidic conditions, the interactions between the PASP layer and DOX molecules can be broken, resulting in gradual release of the DOX molecules. Upon NIR irradiation, the release of DOX could be further accelerated and a photothermal effect from rGO induced. Cellular uptake and cytotoxicity experiments indicate that the drug nanocomposites possess effective anticancer activity. Thus, in this work, we present a useful strategy for the fabrication of pH-responsive drug nanocomposites for combined photothermal and chemical therapy. The nanocomposite can be used as a potential drug delivery system for practical cancer treatment.
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