JOURNAL OF MOLECULAR LIQUIDS
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2023
·
IF 6
Ji Ma,Guoxia Huang,Changxin Mo,Junsheng Li,Liujuan Yan,Qian Zhang
Benzo[b]fluorathene (BbF) is one of common polycyclic aromatic hydrocarbons with strong carcinogenic and teratogenic properties and mutagenicity in the environment. In this work, the mechanism underlying the relationship between BbF and herring sperm DNA (hs–DNA) in vitro under simulated physiological conditions was studied through multi-spectroscopic approaches (fluorescence spectroscopy, UV–Vis spectroscopy, resonance scattering spectra, and circular dichroism) coupled with agarose gel electrophoresis, fluorescence microscopy, and viscosity measurements. UV–vis and fluorescence spectra results showed that the BbF–DNA complexes formed with a binding constant of 8.95 ± 0.19 × 10 5 L/mol, and BbF bound to DNA by intercalative binding. These findings were further confirmed through circular dichroism, potassium iodide quenching experiment, salt ion effect tests, and viscosity measurement. Obtained from the resonance scattering spectral data, the saturation value of DNA with BbF was 2.4, revealing that BbF may cause DNA damage. The thermodynamic parameters revealed that the binding process was entropically driven by the spontaneous reaction between BbF and DNA. The main stabilizing forces between BbF and DNA were van der Waals force and π-π packing. Agarose gel electrophoresis and fluorescence microscopy results intuitively verified that the interaction mode of BbF and DNA was intercalation. Moreover, on the basis of intercalative binding between BbF and DNA, DNA and magnetic beads were used to selectively capture BbF, and the removal rate of BbF was 98.76%. This study provides mechanisms underlying the toxicity of BbF and novel insights into BbF clearance methods based on BbF–DNA intercalation.
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RESEARCH ON CHEMICAL INTERMEDIATES
·
2026
·
IF 3.3
Ma Yong-hu,Ma Fu,Zhao Tiao-bin,Gao Zi-yi,La Ying-hong,Zhao Hong-jian
Limited interfacial charge separation efficiency and insufficient redox capacity severely hinder the practical application of conventional Bi 2 WO 6 -based photocatalysts. To address these issues, a novel Bi(C 2 O 4 )OH/Bi 2 WO 6 heterojunction was constructed via a facile room-temperature one-pot liquid-phase deposition method. Multiple characterizations confirm the intimate interfacial contact between Bi(C 2 O 4 )OH nanorods and uniformly anchored Bi 2 WO 6 nanoparticles, accompanied by the introduction of abundant oxygen vacancies. On the basis of radical trapping experiments, EPR measurements, and electrochemical tests, an S-scheme charge-transfer model is proposed. This model retains the strong redox potentials of both semiconductors, while oxygen vacancies are speculated to act as efficient interfacial charge-trapping and transfer sites to synergistically promote the migration and separation of photogenerated carriers. The optimized 7%Bi(C 2 O 4 )OH/Bi 2 WO 6 composite achieves an RhB removal efficiency of 97.6% within 60 min for 50 mL of RhB solution (30 mg·L -1 ) under 5-W LED lamp irradiation. Radical trapping and EPR tests confirm that ·O 2 - , h⁺, and ·OH are the dominant active species. This work presents a facile and efficient room-temperature fabrication strategy for Bi-based heterojunctions and systematically elucidates the synergistic promotion mechanism between oxygen vacancies and the proposed S-scheme charge-transfer pathway, offering new insights for designing high-performance photocatalysts for organic wastewater remediation.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2023
·
IF 9.9
Yi Han,Min Chao,Chunjia Luo,Luke Yan
Graphitic carbon nitride (g-C 3 N 4 ) is a promising nonmetallic photocatalyst . In this manuscript, B-doped 3D flower-like g-C 3 N 4 mesoporous nanospheres (BMNS) were successfully prepared by self-assembly method. The doping of B element promotes the internal growth of hollow flower-like g-C 3 N 4 without changing the surface roughness structure, resulting in a porous floc structure, which enhances the light absorption and light reflection ability, thereby improving the light utilization rate. In addition, B element provides lower band gap, which stimulates the carrier movement and increases the activity of photogenerated carriers. The photocatalytic mechanism and process of BMNS were investigated in depth by structural characterization and performance testing. BMNS-10 % shows good degradation for four different pollutants, among which the degradation effect on Rhodamine B (RhB) reaches 97 % in 30 min. The apparent rate constant of RhB degradation by BMNS-10 % is 0.125 min −1 , which is 46 times faster compared to bulk g-C 3 N 4 (BCN). And the photocatalyst also exhibits excellent H 2 O 2 production rate under visible light . Under λ > 420 nm, the H 2 O 2 yield of BMNS-10 % (779.9 μM) in 1 h is 15.9 times higher than that of BCN (48.98 μM). Finally, the photocatalytic mechanism is proposed from the results of free radical trapping experiments.
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高影响因子
Journal of Environmental Chemical Engineering
·
2023
·
IF 7.7
Jiapeng Yang,Kai Jia,Shaoyong Lu,Yijun Cao,Grzegorz Boczkaj,Chongqing Wang
In this work, catalytic activity of natural chalcopyrite (CuFeS 2 ) was improved by thermal activation. The modified chalcopyrite was used as efficient catalyst for degradation of organic dye Rhodamine B (RhB) through advanced oxidation process (AOP). Effects of catalyst dosage, H 2 O 2 concentration, reaction temperature, solution pH, anions, and natural organic matter on the degradation efficiency of RhB were investigated. This study revealed that thermal activation at 300 °C changed the chemical valency of surface elements rather than transforming the major chemical phase of natural chalcopyrite. The Fenton-like degradation of RhB was significantly improved by thermally activated chalcopyrite. RhB degradation could be obtained under broad pH and showed high resistance to natural organic matter and anions. Under optimal conditions of H 2 O 2 43.0 mM, catalyst 0.75 g/L, initial pH 5.1, and reaction temperature 25 °C, the degradation of RhB reached 96.7% at 50 min. Based on the rate constant of reaction kinetics, the activation energy for RhB degradation was calculated to be 9 kJ/mol. Radical scavenging experiments and electron paramagnetic resonance (EPR) technique demonstrated that RhB degradation was dominated by the generated hydroxyl radicals in activated chalcopyrite/H 2 O 2 system. The formation of surface sulfates resulted from thermal activation induced the dissolved copper or iron ions, and promoted H 2 O 2 activation and facilitated RhB degradation by reactive hydroxyl radicals. This work provides an in-depth understanding of the mechanism behind thermal activation to enhance the activity of natural chalcopyrite, offering a theoretical basis for utilizing natural minerals for Fenton-like treatment of organic wastewater towards cleaner production.
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JOURNAL OF NATURAL PRODUCTS
·
2022
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IF 4.803
Yichen Tong,Wentao Zhu,Tianzhi Wen,Zere Mukhamejanova,Fang Xu,Qi Xiang,Jiyan Pang
Nonalcoholic fatty liver disease (NAFLD) represents a class of disorders including hepatic steatosis, steatohepatitis, and liver fibrosis. Previous research suggested that xyloketal B (Xyl-B), a marine-derived natural product, could attenuate the NAFLD-related lipid accumulation. Herein, we investigated the protective mechanism of Xyl-B in a high-fat diet (HFD) mice fatty liver model by combining a quantitative proteomic approach with experimental methods. The results showed that the administration of Xyl-B (20 and 40 mg·kg–1·day–1, ip) ameliorated the hepatic steatosis in HFD mice. Proteomic profiling together with bioinformatics analysis highlighted the upregulation of a cluster of peroxisome proliferator-activated receptor-α (PPARα) downstream enzymes mainly related to fatty acid oxidation (FAO) as key changes after the treatment. These changes were subsequently confirmed by bioassays. Moreover, further results showed that the expression levels of PPARα and PPARγ coactivator-1α (PGC1α) were increased after the treatment. The related mode-of-action was confirmed by PPARα inhibition. Furthermore, we evaluated the PPARα-mediated anti-inflammatory and antifibrosis effect of Xyl-B in methionine-choline-deficient (MCD) mice hepatitis and liver fibrosis models. According to the results, the histological features were improved, and the levels of inflammatory factors, adhesion molecules, as well as fibrosis markers were decreased after the treatment. Collectively, these results indicated that Xyl-B ameliorated different phases of NAFLD through activation of the PPARα/PGC1α signaling pathway. Our findings revealed the possible metabolism-regulating mechanism of Xyl-B, broadened the application of xyloketal family compounds, and may provide a new strategy to curb the development of NAFLD.
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ACTA PHARMACOLOGICA SINICA
·
2023
·
IF 8.2
Wu Jun,Zhao Miao,Jin Yu-chen,Li Min,Yu Ke-xin,Yu Hai-bo
Epilepsy is a prevalent and severe neurological disorder and approximately 30% of patients are resistant to existing medications. It is of utmost importance to develop alternative therapies to treat epilepsy. Schisandrin B (SchB) is a major bioactive constituent of Schisandra chinensis (Turcz.) Baill and has multiple neuroprotective effects, sedative and hypnotic activities. In this study, we investigated the antiseizure effect of SchB in various mouse models of seizure and explored the underlying mechanisms. Pentylenetetrazole (PTZ), strychnine (STR), and pilocarpine-induced mouse seizure models were established. We showed that injection of SchB (10, 30, 60 mg/kg, i.p.) dose-dependently delayed the onset of generalized tonic-clonic seizures (GTCS), reduced the incidence of GTCS and mortality in PTZ and STR models. Meanwhile, injection of SchB (30 mg/kg, i.p.) exhibited therapeutic potential in pilocarpine-induced status epilepticus model, which was considered as a drug-resistant model. In whole-cell recording from CHO/HEK-239 cells stably expressing recombinant human GABA A receptors (GABA A Rs) and glycine receptors (GlyRs) and cultured hippocampal neurons, co-application of SchB dose-dependently enhanced GABA or glycine-induced current with EC 50 values at around 5 μM, and application of SchB (10 μM) alone did not activate the channels in the absence of GABA or glycine. Furthermore, SchB (10 μM) eliminated both PTZ-induced inhibition on GABA-induced current ( I GABA ) and strychnine (STR)-induced inhibition on glycine-induced current ( I glycine ). Moreover, SchB (10 μM) efficiently rescued the impaired GABA A Rs associated with genetic epilepsies. In addition, the homologous mutants in both GlyRs-α1(S267Q) and GABA A Rs-α1(S297Q)β2(N289S)γ2L receptors by site-directed mutagenesis tests abolished SchB-induced potentiation of I GABA and I glycine . In conclusion, we have identified SchB as a natural positive allosteric modulator of GABA A Rs and GlyRs, supporting its potential as alternative therapies for epilepsy.
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DIAMOND AND RELATED MATERIALS
·
2023
·
IF 4.1
Jianyun Yang,Xinyue Gu,Liqiong Yang,Minghua Li,Ya Yan,Ye Zhang
Visible-light responsive AgInS 2 (AIS) nanoparticles modified with either pristine multi-walled carbon nanotubes ( p -MWCNTs) or mixed-acid (H 2 SO 4 and HNO 3 ) oxidized multi-walled carbon nanotubes ( o -MWCNTs) were synthesized using a low-temperature liquid phase method. The resulting nanocomposites are denoted as p -MWCNTs/AIS or o -MWCNTs/AIS. The structure, morphology, and optical properties of the samples were characterized using X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), high-resolution transmission electron microscopy (HRTEM), photoluminescence spectroscopy (PL), and ultraviolet-visible diffuse reflectance spectroscopy (UV–Vis DRS). The photocatalytic activity of p / o -MWCNTs/AIS towards the degradation of Rhodamine B (RhB) was investigated, and the optimal proportion of p/o -MWCNTs introduced on AIS was determined. A possible degradation mechanism of RhB over p / o -MWCNTs/AIS was proposed. The results demonstrated that p / o -MWCNTs were successfully incorporated into AIS, and the addition of an appropriate amount of p / o -MWCNTs improved the visible-light photocatalytic activity of AIS. Among the samples, 2 % o -MWCNTs/AIS exhibited the highest visible-light catalytic activity , achieving a degradation efficiency of 95 % within 40 min. The·⋅O 2 − species were identified as the main active species during the photocatalytic degradation process . The introduction of o -MWCNTs not only facilitated the separation of photogenerated electron-hole pairs (e − /h + ) in AIS but also enhanced the visible-light absorption of AIS, leading to a significant improvement in its photocatalytic performance. Furthermore, the incorporation of o -MWCNTs greatly enhanced the cycling stability of AIS for reuse.
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JOURNAL OF MOLECULAR LIQUIDS
·
2023
·
IF 6
Cheng Peng,Xinyu Chen,Yu Yang,Feiyang Luo,Xuehui He,Yan Yu,Qiao Deng,Tianding Hu,Shaoyun Shan,Yunfei Zhi,Lihong Jiang,Hongying Su
The development of advanced strategy to activate persulfate for wastewater treatment is an ever-hot research topic. Herein, a high-performance composite catalyst MIL-68(Fe)/CuBi 2 O 4 (30 %) (M-CBO-30) was prepared by in-situ synthesizing MIL-68(Fe) in the CuBi 2 O 4 . The catalytic performances of M-CBO-30 as heterogeneous catalyst to activate PDS for the Rhodamine B (RhB) degradation were systematically studied. It was shown that the M-CBO-30/PDS system presented an ultrahigh RhB degradation efficiency which could remove 100 % RhB within 5 min only using 0.4 g L − 1 catalyst and 0.4 mM PDS. In addition, the M-CBO-30 could remove RhB at a wide pH range (2–10). One should note that the M-CBO-30 exhibited outstanding reusability which afforded high degradation efficiency after 5 successive recycles. And the catalyst structure remained still after being used for 5 catalytic cycles. Heavy metal ions leaching experiment indicated that Cu 2+ leaching concentration of M-CBO-30 was far lower than that of the city water criterion in Europe. The RhB degradation mechanism by M-CBO-30/PDS system was proposed based on the result of electrochemical experiment, radical quenching test, electron paramagnetic resonance and XPS analysis. The RhB degradation was attributed to the oxidization of reactive oxygen species (i.e., SO 4 •− , •OH and 1 O 2 ). The synergistic effect of redox cycle of surface Fe, Bi and Cu were responsible for the high-efficient PDS activation. The excellent recyclability, outstanding structural stability, wide pH application range, less heavy metal leaching and superhigh RhB degradation efficiency highlights the light application prospect of M-CBO-30 in SR-AOPs-driven RhB decontamination.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2023
·
IF 7.2
Yanbing Sun,Huimin He,Dezhou Zheng,Fuxin Wang,Fanyuan Meng,Wei Xu,Gang Huang,Jing Zhao,Daize Mo,Mark C. Wiliiams,Qi Feng
Recently, ruthenium telluride (RuTe 2 ) has received widespread attention as an effective HER catalyst. In this work, ultrafine and well-dispersed RuTe 2 nanoparticles anchored on nitrogen and boron co-doped graphene (RuTe 2 /BNG) was developed by freeze-drying and facile pyrolysis method, demonstrating a brilliant HER performance. The overpotential of RuTe 2 /BNG at the current density of 10 mA cm −2 is only 34 and 16 mV in 0.5 M H 2 SO 4 and 1.0 M KOH solution, respectively. More importantly, the RuTe 2 /BNG can also maintain significantly robust HER stability during long-term chronopotentiometry measurements. The outstanding HER activity of RuTe 2 /BNG should be ascribed to its properties with abundant defects, large specific surface area, high electronic conductivity and short mass transfer path. Our work offers a new path to fabricate efficient HER catalysts by homogeneously anchoring RuTe 2 on B, N co-doped graphene.
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Advanced Science
·
2023
·Vol. 10
·期 32
·2302618
·
IF 15.1
Wei Zhou,Changsheng Song,Shuyang Li,Miao Liu,Huiwen He,Shaoyu Yang,Jin Xie,Fei Wang,Fang Fang,Dalin Sun,Jie Zhao,Yun Song
All-solid-state sodium-ion batteries have the potential to improve safety and mitigate the cost bottlenecks of the current lithium-ion battery system if a high-performance electrolyte with cost advantages can be easily synthesized. In this study, a one-step dehydrogenation-assisted strategy to synthesize the novel thio-borohydride (Na-B-H-S) electrolyte is proposed, in which both raw material cost and preparation temperature are significantly reduced. By using sodium borohydride (NaBH 4 ) instead of B as a starting material, B atoms can be readily released from NaBH 4 with much less energy and thus became more available to generate thio-borohydride. The synthesized Na-B-H-S (NaBH 4 /Na-B-S) electrolyte exhibits excellent compatibility with current cathode materials, including FeF 3 (1.0–4.5 V), Na 3 V 2 (PO 4 ) 3 (2.0–4.0 V), and S (1.2–2.8 V). This novel Na-B-H-S electrolyte will take a place in mainstream electrolytes because of its advantages in preparation, cost, and compatibility with various cathode materials.
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高影响因子
MOLECULES
·
2023
·Vol. 28
·期 21
·7310
·
IF 4.6
Yiting Gu,Xin Du,Feng Hua,Jianfeng Wen,Ming Li,Tao Tang
Inorganic halide perovskite CsPbI3is highly promising in the photocatalytic field for its strong absorption of UV and visible light. Among the crystal phases of CsPbI3, the δ-phase as the most aqueous stability; however, directly using it in water is still not applicable, thus limiting its dye photodegradation applications in aqueous solutions. Via adopting nitrogen-doped graphene quantum dots (NGQDs) as surfactants to prepare δ-phase CsPbI3nanocrystals, we obtained a water-stable material, NGQDs-CsPbI3. Such a material can be well dispersed in water for a month without obvious deterioration. High-resolution transmission electron microscopy and X-ray diffractometer characterizations showed that NGQDs-CsPbI3is also a δ-phase CsPbI3after NGQD coating. The ultraviolet-visible absorption spectra indicated that compared to δ-CsPbI3, NGQDs-CsPbI3has an obvious absorption enhancement of visible light, especially near the wavelength around 521 nm. The good dispersity and improved visible-light absorption of NGQDs-CsPbI3benefit their aqueous photocatalytic applications. NGQDs-CsPbI3alone can photodegrade 67% rhodamine B (RhB) in water, while after compositing with TiO2, NGQDs-CsPbI3/TiO2exhibits excellent visible-light photocatalytic ability, namely, it photodegraded 96% RhB in 4 h. The strong absorption of NGQDs-CsPbI3in the visible region and effective transfer of photogenerated carriers from NGQDs-CsPbI3to TiO2play the key roles in dye photodegradation. We highlight NGQDs-CsPbI3as a water-stable halide perovskite material and effective photocatalytic adjuvant.Keywords:nitrogen doping;graphene quantum dot;perovskite;photodegradation
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CERAMICS INTERNATIONAL
·
2023
·
IF 5.2
Hong Zhao,Dan Xu,Xiaoyang Duan,Xinyuan Zhou,Wenjun Jia,Wenjie Zhao
In this work, 5 wt‰ Li 2 CO 3 -doped 0.88Ba 0.8 Sr 0.2 TiO 3 -0.12BiMeO 3 (BST-BMe+5‰Li 2 CO 3 , Me = Al 3+ , Ga 3+ , Ta 5+ , and In 3+ ) ceramics were fabricated using solid phase sintering approach. The impacts of different B-site Me ions on the crystalline structure, permittivity stability, energy density , and energy storage efficiency of these ceramics were studied. The XRD results revealed that the mixed tetragonal (T) and pseudo cubic (pC) phase structure was obtained for all the samples. The In/5‰Li 2 CO 3 sample exhibits the optimal energy density of W rec = 1.04 J/cm 3 and the energy efficiency of η = 96% at 170 kV/cm. Meanwhile, the sample shows outstanding temperature stability satisfying the EIA-X8R criteria, which is ascribed to the combined roles of defect dipoles and large lattice distortion. Li 2 CO 3 plays a key role in reducing the sintering temperature , raising the breakdown strength , enhancing the relaxation characteristics, and improving the thermal stability of energy efficiency of the ceramics.
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