MICROCHEMICAL JOURNAL
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2026
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IF 5.2
Shulan Chen,Jiang Huang,Wenyue Chen,Hongwen Wu,Hongliang Tan
Hybridization gating reduces fluorophore ratio-control constraints. • Post-activation dye recruitment limits background from pre-integrated signal dyes. • Immunomagnetic enrichment provides target selectivity for ATP-based sensing. • Chitosan-modified hydrogel limits acid-induced background in portable readout. Rapid bacterial detection in dairy food safety monitoring requires portable platforms that combine analytical sensitivity with target selectivity. Here, we report a hybridization-gated zeolitic imidazolate framework-8 (ZIF-8) ratiometric nanoprobe, designated RSZ, for portable detection of Staphylococcus aureus ( S. aureus ) through adenosine triphosphate (ATP)-triggered DNA duplex signaling. The RSZ probe adopts a dual-zone architecture with Ru(bpy) 3 2+ and ssDNA1 embedded within the ZIF-8 particle interior and ssDNA2 adsorbed on the exterior surface. This architecture separates the stable reference channel from the formation of the responsive fluorescence channel, thereby reducing dependence on precise dual-fluorophore loading and limiting background associated with a pre-integrated responsive fluorophore. Upon ATP-induced framework disruption, ssDNA1 becomes accessible for hybridization with ssDNA2, and the resulting duplex recruits SYBR Green I from solution to generate the responsive fluorescence channel relative to the stable Ru(bpy) 3 2+ reference. To enable field-deployable detection, the nanoprobe is embedded in a chitosan-modified agarose hydrogel in which chitosan maintains a near-neutral microenvironment and limits acid-induced nonspecific activation. Fe 3 O 4 nanoparticles conjugated with porcine immunoglobulin G (Fe 3 O 4 -pIgG) are integrated upstream to selectively capture S. aureus via protein A-pIgG recognition, followed by smartphone red-green-blue analysis without specialized instrumentation. The integrated platform achieves a detection limit of 6 CFU/mL and recoveries of 98.8–101.7% in spiked milk. Therefore, this study demonstrates a hybridization-gated strategy for translating stimulus-induced ZIF-8 disruption into controlled ratiometric signal generation for portable bacterial sensing in food analysis. Download: Download high-res image (106KB) Download: Download full-size image
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SEPARATION AND PURIFICATION TECHNOLOGY
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2026
·
IF 9.1
Chang Liu,Xing Luo,Guowang Shen,Fengfeng Gao,Xueli Huang,Xueying Wang,Qinglong Luo
Ag NPs@Cu-ZIF-8: ZIF-8 modified by partial Cu 2+ doping and Ag NPs loading. • The electrode maintains 128.2 mg・g −1 capacity after 10 Br − cycles. • At optimal conditions, the electrode achieves 147.2 mg·g −1 maximum Br − capacity. • DFT proves Cu 2+ -Ag modification enhances Br − adsorption. Bromide ions (Br − ) are finite and non-renewable strategic resources, and their highly selective recovery is of great significance for the sustainable utilization of brine resources and ecological environmental protection. To address the shortcomings of conventional adsorbents such as poor electrical conductivity and insufficient active sites, an Ag NPs@Cu-ZIF-8 composite was successfully constructed via a synergistic modification strategy involving copper framework doping and silver nanoparticle loading in this study. The composite not only retains the inherent porous structural advantages of ZIF-8 but also effectively overcomes its poor electrical conductivity. Systematic material characterizations combined with density functional theory (DFT) calculations were employed to reveal the microscopic adsorption mechanism of the composite toward Br − in aqueous solution. The results demonstrate that the introduction of silver nanoparticles significantly enhances the electrical conductivity of the material and provides abundant active adsorption sites for Br − capture. Electrochemical test results reveal that the Ag NPs@Cu-ZIF-8 membrane electrode achieves a maximum bromide adsorption capacity of 147.2 mg·g −1 under optimal experimental conditions. The adsorbed bromide can be converted into elemental bromine through extraction, realizing efficient resource recovery. Cycling experiments indicate that the adsorption capacity only drops from 139.7 mg·g −1 to 93.5 mg·g −1 after ten adsorption-desorption cycles under conventional conditions, which reflects outstanding cycling stability. This material presents prominent advantages for the green and efficient recovery of bromine resources. Download: Download high-res image (104KB) Download: Download full-size image
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2026
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IF 5.4
Yanjun Ye,Wenqi Feng,Hui Wang,Honghui Jiang,Juan Liu,Tongxiang Liang
Renewable-electricity-driven CO₂-to-CO electroreduction is a promising approach for sustainable carbon utilization, yet efficient CO production requires precise control of interfacial adsorption, proton-coupled electron transfer, and competing hydrogen evolution. Isolated metal centers are often constrained by linear scaling relationships, hindering the simultaneous optimization of CO₂ activation, *COOH formation, and suppression of the hydrogen evolution reaction. Herein, we report an N-doped carbon catalyst derived from zeolitic imidazolate framework-8, containing neighboring Cu/Ni sites that cooperatively regulate the CO₂-to-CO pathway. Aberration-corrected high-angle annular dark-field scanning transmission electron microscopy reveals atomically dispersed metal features and neighboring bright-spot configurations with a projected-separation distribution centered at approximately 2.35 Å, while localized electron energy-loss spectroscopy supports Cu/Ni coexistence within representative neighboring regions. The optimized catalyst achieves a CO Faradaic efficiency of approximately 99% at −0.70 V versus the reversible hydrogen electrode, with a corresponding CO partial current density of 31.78 mA cm⁻², and maintains stable operation for 52.3 h. Post-reaction scanning transmission electron microscopy and X-ray photoelectron spectroscopy further indicate that the atomically dispersed metal features and metal–N coordination environments are largely preserved after long-term electrolysis. Density functional theory calculations based on a representative adjacent Cu/Ni–Nₓ model show that the free-energy change for the potential-determining *COOH formation at the Ni-centered site is 1.08 eV. Electronic-structure analyses further suggest that neighboring Cu modulates the local electronic environment of Ni, contributing to site-differentiated interfacial reactivity. This work establishes a link between neighboring Cu/Ni sites, interfacial electronic modulation, and CO₂-to-CO performance, providing an interface-engineering strategy for selective CO₂ electroreduction. Download: Download high-res image (156KB) Download: Download full-size image
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CHEMICAL ENGINEERING JOURNAL
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2026
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IF 12.5
Hai Chen,Lisa Mingzhe Sun,Tianqi Wang,Jinrui Zhou,Jiawei Sun,Zhenyao Wang,Xinping He,Chunhai Yi,Jiaxin Guo,Jin Shang,Alicia Kyoungjin An
Thermally activated ZIF-8 exhibits a narrowed bandgap of 2.19 eV. • PS@ZIF-8-T NFM achieves 98.1% PM 2.5 filtration with low pressure drop. • 90.4% formaldehyde degraded within 1 h under visible light. • 81.25% E. coli inactivation achieved after 30 min illumination. • Superhydrophobic surface (WCA 150.6°) ensures self-cleaning ability. Nanofiber membranes offer significant potential for air purification; however, conventional membranes are typically limited to particle filtration and lack functionality against bacteria or volatile organic compounds. To address this, this study fabricated a multifunctional photocatalytic nanofibrous membrane by electrospinning polystyrene (PS) with ZIF-8-T (the air-thermally treated ZIF-8) as a photocatalyst. ZIF-8-T has a specific functional group, isocyanate (-N=C=O), with a band gap of 2.19 eV and exhibits broad-spectrum photo-response properties (200–800 nm). The optimized membrane with a 150 wt% ZIF-8-T loading demonstrated excellent integrated performance: a high PM 2.5 filtration efficiency of 98.1%, rapid degradation of 90.4% formaldehyde within 1 h under illumination, and superhydrophobicity with a water contact angle of 150.6°. Moreover, it achieved an antibacterial rate of 81.25% against E. coli within 30 mins of light exposure. This work presents a viable strategy for designing MOF-based composite membranes that integrate efficient filtration, photocatalytic degradation, and antibacterial functions for advanced air purification. Download: Download high-res image (261KB) Download: Download full-size image
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Food Chemistry-X
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2026
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IF 9.2
Xinyu She,Qian Zhou,Jingjing Song,Bin Wu,Na Xia,Chao Li,Siming Zhu
Lavender essential oil (LEO) has strong antibacterial and antioxidant properties, but its volatility limits practical use in fruit preservation. To address this limitation, we developed a pH-responsive delivery system (LEO@HZIF-8) using tannic acid (TA)-etched hollow ZIF-8 (HZIF-8) to enable controlled release of LEO. Mild etching generated a hollow structure that increased LEO encapsulation efficiency to 68.96%. Results indicate that LEO@HZIF-8 nanoparticles retain a well-defined crystalline structure and release LEO rapidly under acidic conditions, with a release rate of 73.36% at pH 4.5 after 72 h. Furthermore, LEO@HZIF-8 exhibited strong antioxidant activity, with DPPH and ABTS radical-scavenging rates of 85.48% and 78.24%, respectively, and significant antibacterial activity. When incorporated into a sodium alginate/zein (SA/Zein) coating, LEO@HZIF-8 extended the shelf life of white apricots to 63 days and effectively delayed decay, weight loss, and firmness loss. This study demonstrates an efficient pH-responsive delivery strategy for plant essential oils in freshness preservation and provides a basis for developing next-generation smart, eco-friendly active food packaging materials.
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PubMed
高影响因子
Journal of Environmental Chemical Engineering
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2026
·Vol. 14
·期 3
·123101
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IF 7.5
Deyi Han,Lin Ding,Shujuan Yang,Yong Zhang,Haichuan Zhang
This study reports the one-step in-situ assembly of a polydopamine (PDA)@ZIF-8 functional layer on polyethersulfone (PES) ultrafiltration (UF) membranes for high-flux, antifouling dye/salt separation. Leveraging the synergistic effect of dopamine (DA) self-polymerization and the in-situ growth of ZIF-8 during the nonsolvent-induced phase separation (NIPS) process, a highly integrated PDA@ZIF-8 functional layer was successfully constructed on the PES membrane surface. Strong coordination and chelation interactions among Zn 2 + ions, the catechol moieties of PDA, and 2-methylimidazole (2-MIM) increase the casting solution viscosity, triggering delayed demixing and promoting the migration of hydrophilic precursors toward the membrane interface. Structurally, the in-situ assembly of PDA@ZIF-8 significantly increased the selective layer thickness from 4.73 μm to 33.10 μm. The resulting ultrafiltration membrane exhibited exceptional separation efficiency, delivering a Congo Red (CR) rejection rate of over 99.5% while maintaining a salt rejection rate under 5%, enabling the efficient fractionation of dyes and salts. A high pure water flux of 455 L·m −2 ·h −1 at 0.1 MPa is attained, which is attributed to the enhanced surface hydrophilicity and the intrinsic sub-nanometer microporous channels of ZIF-8. Furthermore, the functionalized layer demonstrates remarkable antifouling properties toward anionic dyes, with a stable flux recovery ratio (FRR) exceeding 85% after multiple cycles of CR filtration. This research presents an effective membrane preparation strategy that enhances separation performance while ensuring excellent long-term antifouling stability.
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MICROCHEMICAL JOURNAL
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2026
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IF 5.2
Qianqian Yu,Jingxiao Yu,Qing Yang,Da-Wen Sun,Hongbin Pu
A novel chiral hierarchical porous ZIF-8/Au@Ag bipyramids SERS substrate (HPZA) was constructed. • Developing a dual-chiral synergistic enhancement strategy. • Pioneering the integration of deep learning algorithm with this chiral SERS platform. The widespread use of combined pesticides has led to increasing concerns over mixed pesticide residues in food, posing significant challenges for rapid and reliable detection. Herein, we develop an intelligent surface-enhanced Raman spectroscopy (SERS) platform by integrating a bichiral nanostructured substrate with deep learning for multiplex pesticide analysis. A hierarchical porous chiral ZIF-8 (HPZ) was engineered using L-histidine as a pore-expanding agent and assembled with L-cysteine-directed Au@Ag bipyramids to form the HPZA substrate, enabling synergistic adsorption enrichment and electromagnetic enhancement. The resulting platform exhibits high sensitivity and stability, achieving a detection limit of 9.54 ng/mL for quinalphos in citrus samples. Moreover, when coupled with a fully connected neural network (FCNN), it enables accurate discrimination of multiple pesticides and their mixtures, reaching an identification accuracy of 93.33%. This work presents an integrated material–algorithm strategy for rapid and intelligent detection of pesticide residues, offering a promising approach for food safety monitoring. Download: Download high-res image (105KB) Download: Download full-size image
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Materials Today Chemistry
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2026
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IF 7.4
Shuoye Yang,Jinpeng Wang,Qianqian Cheng,Huajian Yuan,Lin Ju,Xin Wang,Suxi Liu,Ruolan Song,Ning Li,Lu Zhang,Peng Li
Chemotherapy drugs are often associated with toxic side effects and low bioavailability, while solid tumors like breast cancer frequently exhibit multidrug resistance, which limits the clinical efficacy of chemotherapy and other monotherapies. To address these challenges, there is a need for the development of efficient delivery systems capable of transporting various therapeutic agents while introducing novel programmed death mechanisms to achieve synergistic antitumor effects. In this study, zeolite imidazole-8 (ZIF-8) was utilized as a core carrier to load doxorubicin (DOX) and photothermal agent CuS, and further coated by folic acid (FA)-functionalized red blood cell membranes (RBCM) to fabricate the FRCZD delivery system. This system possessed the capacity to target breast cancer MCF-7 cells and their drug-resistant strain, MCF-7/ADR cells. Notably, DOX and CuS were rapidly released in response to both the tumor microenvironment (TME) and near-infrared radiation (NIR). Under light stimulation, CuS induced photothermal therapy (PTT), which further enhanced localized drug accumulation while catalyzing H 2 O 2 to produce toxic hydroxyl radicals (⋅OH) that triggered chemodynamic therapy (CDT). Moreover, excessive intake of Cu 2+ led to mitochondrial metabolic dysfunctions that ultimately initiated cuproptosis. The results demonstrated that FRCZD combined with NIR accelerated cell apoptosis while interfering with cell cycle distribution, consequently inhibiting tumor cell proliferation and migration. In vivo experiment results further corroborated that FRCZD + NIR significantly inhibited tumor growth more effectively than other experimental groups while exhibiting favorable biological safety profiles. Overall, the integrated platform FRCZD could substantially enhance treatment outcomes by inducing cuproptosis in conjunction with chemotherapy, PTT, and CDT approaches, thus holding promise for advancing therapies against drug-resistant tumors.
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高影响因子
ACS Omega
·
2026
·
IF 5.2
Tao Yang,Tao Wang,Tao Shen,Mingrong Dong,Jinkun Liu,Ming Ni,Yan Zhu
Targeting tumor-specific characteristics of acidic microenvironment, elevated H2O2 levels, and thermosensitivity, this study proposed and developed a copper-doped ZIF-8 nanoplatform coloaded with indocyanine green (ICG) and doxorubicin hydrochloride (DOX), designated as Cu-ZIF-8@ICG&DOX (CZID), to establish a multimodal therapeutic system integrating chemodynamic therapy, photothermal therapy, and chemotherapy. Results showed that the 25% copper doping level optimized the structure, achieving 7.46% actual doping content while limiting the average nanoparticle size to 99.6 nm. Dual loading of ICG and DOX induced morphological transition to spherical core–shell architectures, as confirmed by zeta potential reversal, with maximum drug loading capacities of 23.01 μg/mg for ICG and 122.43 μg/mg for DOX. The ZIF-8 framework exhibited pH-responsive degradation under acidic conditions. Released Cu2+ ions mediated continuous hydroxyl radical generation through glutathione-depletion redox cycling, confirming chemodynamic efficacy. Under 808 nm laser irradiation, ICG enabled enhanced photothermal conversion, showing concentration- and power-dependent temperature elevation. Cellular assays revealed efficient CZID internalization by MCF-7 cells, generating significantly higher intracellular reactive oxygen species levels under irradiation and more intense dead cell staining compared to CZI and CZD groups. Such an enhancement was attributed to photothermally accelerated ZIF-8 degradation, promoting Cu2+ ions and DOX release, thereby strengthening chemodynamic–chemotherapy synergy. At the working concentration of 50 μg/mL, CZID induced 95.36% apoptosis in MCF-7 cells while maintaining over 70% viability in MCF-10A normal cells, validating its precise antitumor potential.
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PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2026
·
IF 9.1
Ying Jiang,Wanting Wang,Guichun Luo,Yungui Li,Yapeng Dong,Xiuyuan Zuo,Hai Liang
ZIF-8-decorated biochar hold great potential for heavy metal contaminated wastewater remediation due to the superior adsorption performance of ZIF-8. However, the inevitable blockage of nature pore during preparation restricted the enhancement of adsorption performance and further practical applications. Herein, a novel Zn(NO 3 ) 2 activation-combined in-situ growth strategy was established for porous ZIF-8-decorated biochar (AI-BC@ZIF-8) preparation, this strategy enables the synergistic promotion of porous structure and distribution of ZIF-8 for adsorbent. The AI-BC@ZIF-8 exhibited an excellent adsorption capacity of 249.63 mg/g for Pb, achieving removal efficiency of 99.8% for conventional 50 mg/L Pb-containing wastewater. The adsorption process conforms to the pseudo-second-order kinetic model and the Langmuir isothermal model, indicating the monolayer chemical adsorption mechanism. The results of FTIR, BET and XPS analyses indicate that the adsorption mechanism of AI-BC@ZIF-8 is electrostatic interaction, N-coordination, precipitation, ion-exchange and pore-filling. Overall, this adsorbent demonstrates outstanding adsorption performance, showing its great potential in efficient and low-cost water purification. This work provides a viable strategy for the synthesis of highly porous and efficient ZIF-8-decorated biochar for heavy metal removal from wastewater.
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JOURNAL OF MEMBRANE SCIENCE
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2026
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IF 8.8
Haojie Ren,Zongkai Liu,Bingquan Hua,Nan Yang,Zhengqi Chen,Xiuxiu Ren,Meng Guo,Guanying Dong,Jing Zhong,Yatao Zhang
Seamless integration at the interphase is the foremost issue delaying the development of high-performance mixed matrix membranes (MMMs). Here we report an in-situ crosslinking strategy to effectively integrate the solvent-assisted linker exchange (SALE)-derived ZIF-8 with amidoxime-modified PIM-1 (AOPIM-1) for the challenging propylene/propane separation. In this crosslinking system, the AOPIM-1 polymer matrix can chemically anchor to the surrounding ZIF-8 fillers, promoting the formation of core-shell-like structures, thereby improving interfacial compatibility and filler dispersion. As a result, both high propylene permeability and high selectivity are readily achieved at a low filler loading (10 wt%), significantly surpassing the single- and mixed-gas upper bounds. Additionally, we demonstrate a contraction behavior in ZIF-8 unit cells that correlates with filler loading. Despite the persistence of excellent filler dispersion in highly loaded MMMs, excessive unit cell contraction leads to undesirable interfacial debonding and blocked transport through filler, ultimately deteriorating separation performance. Thus, the in-situ crosslinking imparts a ‘double-edged sword’ effect―simultaneously ensuring superior interfacial compatibility while inducing controllable ZIF-8 lattice contraction. These insights are expected to provide valuable guidance for the rational design and performance optimization of MOF-based MMMs via in-situ crosslinking.
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Food Analytical Methods
·
2026
·Vol. 19
·期 9
·248
·
IF 3
Qin Shili,Zhao Dongsheng,Jin Fenglong,Qin Yuting,Liang Xinyu,Liu Jingwen,Chu Hongtao,Gao Lidi,Zhao Ming
In this study, the octahedral core–shell ZIF-8@UiO-66-NH 2 composite, exhibiting high crystallinity, microporous structural properties and multifunctional groups, was synthesized, characterized, and applied for the first time as stationary phase in capillary electrochromatography. The baseline separation of four groups containing 14 analytes was achieved within 11.6 min, with resolution of at least 1.51. Compared to the individual components of ZIF-8 and UiO-66-NH 2 used as chromatographic stationary phase, the bonded capillary column based on ZIF-8@UiO-66-NH 2 exhibited the improvement in resolution and column efficiency (theoretical plate numbers) ranging from 68.14 to 918.75% and from 3.92 to 398.31%, respectively, and sample loading capacity increased by ≥ 26.8%. Furthermore, an accurate, rapid, and reliable electrochromatography method was developed for the qualitative and quantitative analysis of thiamphenicol and florfenicol in pork meat. The limits of detection and quantification for thiamphenicol were 0.34 μg/mL and 1.75 μg/mL, and for florfenicol, 1.00 μg/mL and 5.82 μg/mL, with sample recoveries in the range of 96.00 to 108.00% and the standard deviations less than 4.59%. This work not only confirmed the potential of MOF@MOF composite as high-performance stationary phases but also broadened the electrochromatography application in food inspection. Graphical
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危险品化学品经营许可证（带存储）