ACS Sustainable Chemistry & Engineering
·
2014
·
IF 0
Rui-Ying Bao,Wei Yang,Xin-Feng Wei,Bang-Hu Xie,Ming-Bo Yang
Melt processing of polymers is preferable in industry. Unfortunately, for high molecular weight (Mw) poly(l-lactide)/poly(d-lactide) (PLLA/PDLA) blends, exclusive formation of stereocomplex (sc) crystallites from the melt has never been achieved. We proposed a new and simple approach to enhance the melt crystallization of sc crystallites from high Mw PLLA/PDLA by using poly(ethylene glycol) (PEG). The crystallizability of the PLLA/PDLA blend is greatly enhanced by PEG during crystallization from the melt. The resulted crystalline structures depend on the Mw and content of PEG, and the crystallinity of sc crystallites increases with increasing content or decreasing Mw of PEG. More importantly, exclusive formation of sc crystallites is achieved in the blends with 10% PEG having Mw values of 1000 or 2000 g mol–1. Polarized optical microscopy (POM) observation shows that the spherulitic growth rates of sc crystallites are accelerated. The results demonstrate that segmental mobility of polylactides (PLA) chains plays a dominant role on the formation of sc crystallites from melt and provide a simple way to prepare sc crystallites from high Mw PLA by melt blending and enlarge the applications of PLA.
研究领域:
高分子科学
·
材料工程
·
聚合物结晶
✓ 已验证
DOI
ACS Applied Materials & Interfaces
·
2022
·
IF 10.383
Haoqiang Wang,Yu Wang,Yani Liu,Shuming Dou,Wei Gan,Qunhui Yuan
To alleviate kinetics imbalance and capacity insufficiency simultaneously, a novel hierarchical structure (SnCu2Se4/d-Ti3C2Tx/NPC) composed of delaminated Ti3C2Tx, SnCu2Se4 nanoparticles, and N-doped porous carbon layers is designed as a battery-type anode for lithium/sodium ion hybrid capacitor (LIC/SIC). The combination of SnCu2Se4 nanoparticles with high specific capacity, d-Ti3C2Tx with accelerated ion diffusion path, and NPC with enhanced electronic conductivity makes the SnCu2Se4/d-Ti3C2Tx/NPC composite possess excellent cycling stabilities in half-cell lithium-ion and sodium-ion batteries (LIB and SIB), with capacities of 114 mAh g–1 after 6000 cycles at 10 A g–1 for LIB and 296 mAh g–1 after 900 cycles at 1.0 A g–1 for SIB. The rate performance is also outstanding, with recovered capacity of 738 mAh g–1 at 0.1 A g–1 after cycles at current densities up to 50 A g–1 for LIB. Subsequently, LIC and SIC based on the SnCu2Se4/d-Ti3C2Tx/NPC anode and activated carbon cathode exhibit high energy densities of 147.9 and 158.6 Wh kg–1 at a power density of 100 W kg–1, respectively. They also possess distinctive long lifespans with capacity retentions of 78 and 81% after 10,000 cycles at 1.0 A g–1, respectively, demonstrating the feasibility of SnCu2Se4/d-Ti3C2Tx/NPC toward energy devices requiring high energy density, power density, and long-term stability.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Sustainable Chemistry & Engineering
·
2022
·
IF 9.224
Yu Peng,Luyao Jiang,Junhua Di,Cuiluan Ma,Qi Li,Yucai He
Biobased 2,5-bis(hydroxymethyl)furan is a versatile building block for the production of drugs, polymers, crown ethers, bioactive compounds, and value-added intermediates. To explore a more efficient route to synthesize 2,5-bis(hydroxymethyl)furan, a tandem transformation by quick dehydration with a deep eutectic solvent betaine:benzenesulfonic acid (Bet:BSA) and mild bioreduction with recombinant Escherichia coli (E. coli) DCF was developed for converting d-fructose into 2,5-bis(hydroxymethyl)furan. The 5-hydroxymethylfurfural yield reached 62.3 ± 1.6% (based on d-fructose) in Bet:BSA at 120 °C after a short time (2 min). d-Fructose-valorized 5-hydroxymethylfurfural was biologically transformed to 2,5-bis(hydroxymethyl)furan by newly constructed recombinant E. coli DCF containing reductase and formate dehydrogenase at 40 °C and pH 7.5 after 48 h, with a yield of 99.6 ± 0.1% (based on 5-hydroxymethylfurfural) in Bet:BSA-water containing the cosubstrate HCOONa (5-HMF-to-HCOONa molar ratio, 1:2.5). Meanwhile, 150 mM commercial 5-hydroxymethylfurfural was transformed into 2,5-bis(hydroxymethyl)furan in a yield of 94.4 ± 0.9%. An efficient hybrid process was constructed to valorize d-fructose to 2,5-bis(hydroxymethyl)furan in Bet:BSA-water, which has good industrial application potential.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
·
2022
·Vol. 103
·期 2
·779-791
·
IF 4.125
Huanhuan Teng,Yi Zhang,Chuanshan Jin,Tongsheng Wang,Shengzhuo Huang,Lei Li,Songzi Xie,Deling Wu,Fengqing Xu
BACKGROUND Polygonatum cyrtonema Hua is cultivated for its edible and medical value. The steam-processed rhizome of P. cyrtonema is the main form for daily consumption and it has been used traditionally in tonics for treating various age-related disorders. The aim of our study was to compare the physicochemical properties and antioxidant activity of polysaccharides respectively extracted from crude P. Cyrtonema (PCPC), and steam-processed P. cyrtonema (PCPS), and to explore a possible underlying antioxidant mechanism. RESULTS The PCPC with a molecular weight of 4.35 × 10 3 Da mainly consisted of fructose and trace amounts of glucose, whereas PCPS with 4.24 × 10 4 Da was composed of fructose, arabinose, glucose, xylose, mannose, galacturonic acid and glucuronic acid. The PCPC had a triple-helical conformation whereas PCPS was a random coil. Both exhibited free radicals- scavenging activity in vitro . In a mouse model of oxidative damage, PCPC or PCPS treatment significantly reversed histopathological alterations, reactive oxygen species (ROS) accumulation and the reduction of antioxidant enzyme activity. They both also promoted Nrf2 nuclear transport by decreasing Keap-1 expression and increasing HO-1 expression. Both in vitro and in vivo , PCPS exhibited more potent antioxidant activity than PCPC. CONCLUSION Overall, the results suggest that PCPS has a stronger effect on the prevention of oxidative damage by activating Nrf2/HO-1 antioxidant signaling. This study demonstrates the role of steam-processed P. cyrtonema rhizome and provides valuable perspective for PCPS as a functional agent. © 2022 Society of Chemical Industry.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2022
·
IF 12.545
Fei Chen,Daian Chen,Ting Deng,Jishan Li
Pathogenic bacteria are a major cause of foodborne diseases, which not only seriously threaten human safety but also cause significant losses for the national economy. Therefore, it is very important and urgent to develop a method for the detection of pathogenic bacteria with high accuracy, high sensitivity, and easy interpretation for use in food safety and medical hygiene. Herein, based upon the sensitive color changes induced by the dispersion and aggregation states of gold nanoparticles (AuNPs), a point-of-care (POCT) colorimetric assay was constructed for the rapid and sensitive visual detection of pathogenic bacteria. The POCT visual sensing system is composed of two individual elements: (1) an alkaline phosphatase/graphene oxide (GO@PEI-ALP) nanoconjugate that can release free ALP molecules in the presence of pathogenic bacteria; (2) D-glucose-6-phosphate (pGlu) and 3-aminobenzene boric acid (AMBA)-functionalized AuNPs (pGlu/AMBA-AuNPs) that are cross-linked upon the digestion of pGlu by free ALP molecules, resulting in a significant color change. Under optimized conditions, the detection limit of this sensing system for target bacteria was as low as 24 CFU mL −1 and was successfully applied to complex real samples. This proposed rapid colorimetric assay has high sensitivity, accuracy, and practicability with an intuitive signal and is expected to provide new inspiration for the detection of pathogenic bacteria.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2022
·Vol. 139
·期 22
·52268
·
IF 3.057
Zhixiang Cui,Yue Fan,Xiaolong Liu,Junhui Si,Qianting Wang
Nowadays, the environmental problems caused by industrial oily wastewater and offshore oil leakage are becoming more and more serious. Here, the 3-D porous polyurethane/deacetylated acetate cellulose (TPU/d-CA) composite foam with outstanding mechanical property and oil/water separation performance was successfully prepared. The morphology, wettability, mechanical properties, and oil/water separation performances had been systematically studied. The results showed that TPU/d-CA composite foam could be used as water and oil removing material, respectively, for a series of oil/water mixture only under gravity force, due to its lipophilicity and hydrophilicity. It has high-separation flux, which can reach up to 43,000 L/m 2 ·h and 85,000 L/m 2 ·h for water and oil, respectively and all the separation efficiency exceeds 98%. It also can be used as adsorbent material to absorb various oils, and the absorption capacity for carbon tetrachloride reached up to 34 g/g. Moreover, it can selectively, rapidly, and continuously separate oil or water by assisted peristaltic pump. After 15 cycle times, its separation efficiency is still as high as 98%. It has excellent comprehensive mechanical properties and antifouling ability. These results indicated that 3-D TPU/d-CA composite foam has broadly application prospects in oil/water separation field.
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2021
·
IF 7.514
Dan Bu,Zong-cai Tu,Hui Wang,Yue-ming Hu,Qing Sun,Guang-xian Liu
The mechanism of d -allose in reducing the allergenicity and digestibility of ultrasound-pretreated α-lactalbumin (α-LA) was studied. The intensity reduction and peak red shift occurred in fluorescence spectra of glycated samples. Enzyme-linked immunosorbent assay and basophil degranulation analysis showed that d -allose significantly reduced the allergenicity of α-LA, and ultrasound-pretreated α-LA showed the lowest allergenicity after glycation. Compared with α-LA, the degree of hydrolysis decreased in glycated samples. Size-exclusion high-performance liquid chromatography showed that the glycated α-LA was resistant to digestive enzymes. The glycated sites and average degree of substitution per peptide molecule were determined using LC Orbitrap MS/MS. These results suggested that the masking of linear allergenic epitopes by glycation could reduce the allergenicity. Therefore, the combination of ultrasound pretreatment and glycation is a potential method to reduce protein allergenicity in food processing and provides a useful approach for the application of rare sugars in food processing.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Advanced Healthcare Materials
·
2023
·
IF 10
Pengfei Sun,Wan Yang,Jiarong He,Liuliang He,Pengfei Chen,Wenjuan Xu,Qingming Shen,Daifeng Li,Quli Fan
Cancer seriously affects the quality of life of patients with the disease. Synergistic chemotherapy and photothermal therapy (PTT) have emerged as a promising anticancer paradigm to achieve expected therapeutic effects while mitigating side effects. However, the chemo/PTT combination therapy suffers from limited penetration depth, thermo-resistance performance of tumor cells, and low drug bioavailability. Herein, we developed multifunctional nanoparticles (BTP/DOX/2DG NPs) coloaded with near-infrared region II (NIR-II) light excitation donor–acceptor–donor (D-A-D) small molecules, doxorubicin (DOX), and 2-deoxy-D-glucose (2-DG) for reinforced starvation/chemo/NIR-II PTT combination therapy. Our synthesized phenylboronic acid (PBA)-modified water-soluble D-A-D molecule (BBT-TF-PBA) not only exhibits high binding ability to DOX and 2-DG through donor–acceptor coordination interactions PBA-diol bonds but also serve as a photoactive agent for NIR-II fluorescence imaging, NIR-II photoacoustic imaging, and NIR-II PTT. Under the acidic and oxidizing conditions in the tumor microenvironment, donor–acceptor coordination interactions and PBA-diol bond are decomposed, simultaneously releasing DOX and 2-DG from BTP/DOX/2DG NPs to achieve effective chemotherapy and starvation therapy. 2-DG also effectively inhibits the expression of heat shock protein and further enhances NIR-II PTT and chemotherapy efficiency. In vitro and in vivo experiments demonstrated the combination effect of BTP/DOX/2DG NPs for chemotherapy, NIR-II PTT, and starvation therapy. This article is protected by copyright. All rights reserved
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2021
·
IF 6.953
Junxin Zhao,Shichang Liu,Yifang Gao,Maomao Ma,Xianghui Yan,Ding Cheng,Dongman Wan,Zheling Zeng,Ping Yu,Deming Gong
Enzymatic degradation has become the most promising approach to degrading organic ester compounds. In this study, Bacillus licheniformis NCU CS-5 was isolated from the spoilage of Cinnamomum camphora seed kernel, and its extracellular lipase was purified, with a specific activity of 192.98 U/mg. The lipase was found to be a trimeric protein as it showed a single band of 27 kDa in SDS-PAGE and 81 kDa in Native-PAGE. It was active in a wide range of temperatures (5–55 °C) and pH values (6.0–9.0), and the optimal temperature and pH value were 40 °C and 8.0, respectively. The enzyme was active in the presence of various organic solvents, metal ions, inhibitors and surfactants. Both crude and purified lipase retained more than 80% activity after 5 h in the presence of commercial detergents, suggesting its great application potential in detergent industry. The highest activity was found to be towards medium- and long-chain fatty acids (C 6 -C 18 ). Peptide mass spectrometric analysis of the purified lipase showed similarity to the lipase family of B. licheniformis . Furthermore, it degraded more than 90% 2,4-D butyl ester to its hydrolysate 2,4-D within 24 h, indicating that the novel lipase may be applied to degrade organic ester pesticides.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TALANTA
·
2021
·
IF 6.057
Haizhi Zhang,Huanyu Yang,Pei Liu,Xinguang Qin,Gang Liu
A rapid colorimetric method for detecting sodium benzoate in food products was established based on the d -amino acid oxidase (DAAO) and 2D metal organic framework (2D MOF) nanosheets mediated cascade enzyme reactions. Firstly, the synthesized 2D MOF nanosheets served as high efficient nanozyme with outstanding peroxidase-like catalytic activity and catalyzed the color reaction between H 2 O 2 and 3, 3’, 5, 5′- tetramethylbenzidine. Secondly, sodium benzoate as a competitive inhibitor of DAAO, could influence the production of H 2 O 2 in DAAO mediated oxidation reaction. After a combination of those two reactions, this colorimetric quantitative method was constructed and validated for sodium benzoate determination with wide linear range (2.0–200.0 μM), low limit of detection (2.0 μM), high accuracy (recovery rate in 95.80–108.00%) and satisfied selectivity . Lastly, this method was utilized to analyze sodium benzoate concentration in juice, wine and vinegar by naked eyes.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2020
·Vol. 56
·期 1
·731-745
·
IF 3.553
Wang Jingguang,Gao Huichang,Hu Yang,Zhang Naiyue,Zhou Wuyi,Wang Chaoyang,Binks Bernard P.,Yang Zhuohong
Abstract Biocompatible and bioactive scaffolds with multiscale porosity, shape memory effect and drug delivery performance are highly promising in bone tissue engineering applications within the approach of minimally invasive surgical implantation. In this study, we report an effective method to fabricate multiscale porous bioactive (MPB) scaffolds with shape memory effect by freeze drying of 3D printed high internal phase Pickering emulsion (Pickering HIPE) templates stabilized by hydrophobically modified hydroxyapatite and silica nanoparticles. MPB scaffolds containing a shape memory polymer matrix of poly(D,L-lactide-co-trimethylene carbonate) display high porosity and fully interconnected filament networks with multiscale pore structures. The in vitro biomineralization study verifies that MPB scaffolds are bioactive with the apatite formation ability. The thermal property testing shows that the glass transition temperature of MPB scaffolds is easily tuned to fall between 45.9 and 49.1 °C by varying the HIPE composition. Moreover, MPB scaffolds exhibit observable shape memory properties with fast shape recovery. The antibacterial drug enrofloxacin can be efficiently loaded into MPB scaffolds and then released in a sustained manner displaying effective antimicrobial effect. Furthermore, cell culture assays confirm that MPB scaffolds could sustain the cell growth, proliferation and osteogenic differentiation, indicating the cytocompatibility and osteoinduction activity of MPB scaffolds. Therefore, combining freeze drying with 3D printing of Pickering HIPE templates paves the way towards MPB scaffolds with shape memory effect, which are promising as minimally invasive implantation scaffolds in bone tissue engineering applications. Graphic Abstract
✓ 已验证
产品关联
DOI
高影响因子
NATURAL PRODUCT RESEARCH
·
2020
·
IF 2.158
Xiaomei Li,Xiaoman Li,Jing Zhu,Haoxin Wang,Chunhua Lu
One new carbamothioic S-acid derivative (1) and five known kigamicin derivatives (2–6) were isolated from the fermentation extract of Amycolatopsis alba DSM 44262Δabm9 elicited by N-acetyl-D-glucosamine. HPLC-DAD-UV analyses indicated that the DSM 44262Δabm9 strain did not produce these metabolites originally and the production of 1–6 was induced by adding 25 mM N-acetyl-D-glucosamine in the culture medium. The structures of 1–6 were identified on the basis of NMR spectroscopic data and high-resolution ESIMS. These results highlight that addition of N-acetyl-D-glucosamine in the microbial culture medium could activate cryptic gene expression, induce and increase the production of new or known secondary metabolites.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）